Publication Information

{'id': 'https://openalex.org/W2163640310', 'doi': 'https://doi.org/10.1002/jnr.21946', 'title': 'Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus', 'display_name': 'Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus', 'publication_year': 2008, 'publication_date': '2008-11-19', 'ids': {'openalex': 'https://openalex.org/W2163640310', 'doi': 'https://doi.org/10.1002/jnr.21946', 'mag': '2163640310', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19021291'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/jnr.21946', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jnr.21946', 'source': {'id': 'https://openalex.org/S76417895', 'display_name': 'Journal of Neuroscience Research', 'issn_l': '0360-4012', 'issn': ['0360-4012', '1097-4547'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jnr.21946', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019697077', 'display_name': 'Akvilė Norkutė', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Akvile Norkute', 'raw_affiliation_strings': ['A. Norkute and A. Hieble contributed equally to this work.', 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}, {'raw_affiliation_string': 'A. Norkute and A. Hieble contributed equally to this work.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079411410', 'display_name': 'Andrea Hieble', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Andrea Hieble', 'raw_affiliation_strings': ['A. Norkute and A. Hieble contributed equally to this work.', 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}, {'raw_affiliation_string': 'A. Norkute and A. Hieble contributed equally to this work.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103443326', 'display_name': 'Alena Braun', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Alena Braun', 'raw_affiliation_strings': ['Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048788839', 'display_name': 'Sonja Johann', 'orcid': 'https://orcid.org/0000-0002-9312-2220'}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Sonja Johann', 'raw_affiliation_strings': ['Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034723198', 'display_name': 'Tim Clarner', 'orcid': 'https://orcid.org/0000-0002-8180-7775'}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Tim Clarner', 'raw_affiliation_strings': ['Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069807833', 'display_name': 'Werner Baumgärtner', 'orcid': 'https://orcid.org/0000-0002-3160-2050'}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Werner Baumgartner', 'raw_affiliation_strings': ['Department of Cellular Neurobionics, Institute of Zoology, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cellular Neurobionics, Institute of Zoology, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088104480', 'display_name': 'Cordian Beyer', 'orcid': 'https://orcid.org/0000-0003-3926-2553'}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Cordian Beyer', 'raw_affiliation_strings': ['Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063091682', 'display_name': 'Markus Kipp', 'orcid': 'https://orcid.org/0000-0001-5043-9052'}, 'institutions': [{'id': 'https://openalex.org/I887968799', 'display_name': 'RWTH Aachen University', 'ror': 'https://ror.org/04xfq0f34', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I887968799']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Markus Kipp', 'raw_affiliation_strings': ['Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany', 'institution_ids': ['https://openalex.org/I887968799']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5063091682'], 'corresponding_institution_ids': ['https://openalex.org/I887968799'], 'apc_list': {'value': 4640, 'currency': 'USD', 'value_usd': 4640, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.315, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 109, 'citation_normalized_percentile': {'value': 0.873915, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '87', 'issue': '6', 'first_page': '1343', 'last_page': '1355'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10608', 'display_name': 'Neurogenesis and neuroplasticity mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10608', 'display_name': 'Neurogenesis and neuroplasticity mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10137', 'display_name': 'Multiple Sclerosis Research Studies', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/astrocytosis', 'display_name': 'Astrocytosis', 'score': 0.94462156}], 'concepts': [{'id': 'https://openalex.org/C2908656565', 'wikidata': 'https://www.wikidata.org/wiki/Q4811564', 'display_name': 'Astrocytosis', 'level': 3, 'score': 0.94462156}, {'id': 'https://openalex.org/C2781161787', 'wikidata': 'https://www.wikidata.org/wiki/Q48360', 'display_name': 'Hippocampus', 'level': 2, 'score': 0.81580305}, {'id': 'https://openalex.org/C2779830541', 'wikidata': 'https://www.wikidata.org/wiki/Q1622829', 'display_name': 'Microglia', 'level': 3, 'score': 0.65029246}, {'id': 'https://openalex.org/C148762608', 'wikidata': 'https://www.wikidata.org/wiki/Q3748185', 'display_name': 'Hippocampal formation', 'level': 2, 'score': 0.5843911}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.56882894}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.5540923}, {'id': 'https://openalex.org/C2780640218', 'wikidata': 'https://www.wikidata.org/wiki/Q8277', 'display_name': 'Multiple sclerosis', 'level': 2, 'score': 0.51001084}, {'id': 'https://openalex.org/C2778609137', 'wikidata': 'https://www.wikidata.org/wiki/Q105790271', 'display_name': 'Myelin', 'level': 3, 'score': 0.47529233}, {'id': 'https://openalex.org/C2781192897', 'wikidata': 'https://www.wikidata.org/wiki/Q822050', 'display_name': 'White matter', 'level': 3, 'score': 0.4600179}, {'id': 'https://openalex.org/C2776464000', 'wikidata': 'https://www.wikidata.org/wiki/Q545787', 'display_name': 'Dentate gyrus', 'level': 3, 'score': 0.4426005}, {'id': 'https://openalex.org/C2776168963', 'wikidata': 'https://www.wikidata.org/wiki/Q7168164', 'display_name': 'Perforant path', 'level': 4, 'score': 0.41087055}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.3744442}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36050886}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.2220822}, {'id': 'https://openalex.org/C143409427', 'wikidata': 'https://www.wikidata.org/wiki/Q161238', 'display_name': 'Magnetic resonance imaging', 'level': 2, 'score': 0.19833833}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.18920416}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.07387453}, {'id': 'https://openalex.org/C126838900', 'wikidata': 'https://www.wikidata.org/wiki/Q77604', 'display_name': 'Radiology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003471', 'descriptor_name': 'Cuprizone', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D003711', 'descriptor_name': 'Demyelinating Diseases', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003471', 'descriptor_name': 'Cuprizone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003711', 'descriptor_name': 'Demyelinating Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003711', 'descriptor_name': 'Demyelinating Diseases', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D005911', 'descriptor_name': 'Gliosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005911', 'descriptor_name': 'Gliosis', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D005911', 'descriptor_name': 'Gliosis', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017628', 'descriptor_name': 'Microglia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017628', 'descriptor_name': 'Microglia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008854', 'descriptor_name': 'Microscopy, Electron', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009103', 'descriptor_name': 'Multiple Sclerosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009186', 'descriptor_name': 'Myelin Sheath', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D009186', 'descriptor_name': 'Myelin Sheath', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009836', 'descriptor_name': 'Oligodendroglia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009836', 'descriptor_name': 'Oligodendroglia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D020133', 'descriptor_name': 'Reverse Transcriptase Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/jnr.21946', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jnr.21946', 'source': {'id': 'https://openalex.org/S76417895', 'display_name': 'Journal of Neuroscience Research', 'issn_l': '0360-4012', 'issn': ['0360-4012', '1097-4547'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19021291', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/jnr.21946', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jnr.21946', 'source': {'id': 'https://openalex.org/S76417895', 'display_name': 'Journal of Neuroscience Research', 'issn_l': '0360-4012', 'issn': ['0360-4012', '1097-4547'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.81, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 70, 'referenced_works': ['https://openalex.org/W1536622417', 'https://openalex.org/W1552123779', 'https://openalex.org/W1678027485', 'https://openalex.org/W1966515383', 'https://openalex.org/W1969710690', 'https://openalex.org/W1971728959', 'https://openalex.org/W1974525090', 'https://openalex.org/W1976451072', 'https://openalex.org/W1981912305', 'https://openalex.org/W1982783229', 'https://openalex.org/W1985853441', 'https://openalex.org/W1987057401', 'https://openalex.org/W1994127066', 'https://openalex.org/W1994718306', 'https://openalex.org/W1999811418', 'https://openalex.org/W2001356567', 'https://openalex.org/W2003681394', 'https://openalex.org/W2004912900', 'https://openalex.org/W2005768872', 'https://openalex.org/W2007948644', 'https://openalex.org/W2011164123', 'https://openalex.org/W2016284100', 'https://openalex.org/W2016436821', 'https://openalex.org/W2017271286', 'https://openalex.org/W2019533732', 'https://openalex.org/W2025070618', 'https://openalex.org/W2025351121', 'https://openalex.org/W2030377258', 'https://openalex.org/W2030496214', 'https://openalex.org/W2031781387', 'https://openalex.org/W2036675289', 'https://openalex.org/W2037653184', 'https://openalex.org/W2042271113', 'https://openalex.org/W2044282009', 'https://openalex.org/W2050788121', 'https://openalex.org/W2051385458', 'https://openalex.org/W2051887885', 'https://openalex.org/W2059195671', 'https://openalex.org/W2060129459', 'https://openalex.org/W2065806194', 'https://openalex.org/W2068390593', 'https://openalex.org/W2069400081', 'https://openalex.org/W2071263945', 'https://openalex.org/W2071946866', 'https://openalex.org/W2075358654', 'https://openalex.org/W2077013720', 'https://openalex.org/W2084887202', 'https://openalex.org/W2090929107', 'https://openalex.org/W2096980', 'https://openalex.org/W2100657212', 'https://openalex.org/W2100904149', 'https://openalex.org/W2101502818', 'https://openalex.org/W2103029732', 'https://openalex.org/W2104218779', 'https://openalex.org/W2118516890', 'https://openalex.org/W2118917448', 'https://openalex.org/W2123947993', 'https://openalex.org/W2128752949', 'https://openalex.org/W2135012547', 'https://openalex.org/W2139039927', 'https://openalex.org/W2145944042', 'https://openalex.org/W2148353419', 'https://openalex.org/W2153387493', 'https://openalex.org/W2158064024', 'https://openalex.org/W2164721910', 'https://openalex.org/W2167975586', 'https://openalex.org/W2327520147', 'https://openalex.org/W4235275354', 'https://openalex.org/W4242191995', 'https://openalex.org/W4250145052'], 'related_works': ['https://openalex.org/W2412674874', 'https://openalex.org/W2402272727', 'https://openalex.org/W2168377218', 'https://openalex.org/W2153376189', 'https://openalex.org/W2147376325', 'https://openalex.org/W2086005278', 'https://openalex.org/W2050305231', 'https://openalex.org/W2031089116', 'https://openalex.org/W2029517162', 'https://openalex.org/W1979133354'], 'abstract_inverted_index': {'Abstract': [0], 'Memory': [1], 'impairment': [2], 'is': [3], 'outstanding': [4], 'within': [5], 'the': [6, 21, 47, 57, 127, 132, 140, 192], 'spectrum': [7], 'of': [8, 24, 29, 38, 49, 99, 120, 194], 'cognitive': [9, 39], 'deficits': [10], 'in': [11, 20, 32, 64, 107, 117, 139], 'multiple': [12], 'sclerosis': [13], '(MS)': [14], 'patients.': [15, 26], 'Demyelination': [16, 114], 'has': [17, 52], 'been': [18, 53], 'reported': [19], 'hippocampus': [22, 30, 50, 101, 195], 'formation': [23], 'MS': [25, 33], 'The': [27, 70], 'degree': [28], 'lesions': [31], 'strongly': [34], 'correlates': [35], 'with': [36], 'progression': [37], 'dysfunction.': [40], 'Because': [41], 'no': [42], 'appropriate': [43, 188], 'animal': [44, 184], 'model': [45, 60, 185], 'for': [46, 80, 191], 'study': [48], 'demyelination': [51, 63, 98, 180], 'established,': [54], 'we': [55], 'used': [56], 'cuprizone': [58], 'mouse': [59], 'to': [61, 103, 186], 'investigated': [62, 167], 'young': [65, 108], 'adult': [66, 109], 'and': [67, 82, 87, 110, 122, 145, 154, 173], 'aged': [68, 111], 'mice.': [69, 113], 'myelin': [71], 'status': [72], 'was': [73, 115, 163], 'analyzed': [74], 'by': [75], 'classical': [76], 'histological': [77], 'staining,': [78], 'immunocytochemistry': [79], 'proteolipoprotein,': [81], 'electron': [83], 'microscopy.': [84], 'Oligodendrocyte,': [85], 'astroglial,': [86], 'microglia': [88, 161], 'markers': [89], 'were': [90], 'studied.': [91], 'Cuprizone': [92], 'intoxication': [93], 'induced': [94], 'an': [95, 182], 'almost': [96], 'complete': [97], 'distinct': [100], 'subregions': [102], 'a': [104, 118], 'similar': [105], 'extent': [106], 'male': [112], 'pronounced': [116], 'subset': [119], 'white': [121], 'gray': [123], 'matter': [124], 'areas,': [125], 'i.e.,': [126], 'stratum': [128, 137], 'lacunosum': [129], 'moleculare': [130], 'containing': [131], 'perforant': [133], 'path,': [134], 'medial': [135], 'alveus,': [136], 'pyramidale': [138], 'cornu': [141], 'ammonis': [142], '2/3': [143], 'region,': [144], 'hilus': [146], 'region.': [147], 'Besides': [148], 'demyelination,': [149], 'affected': [150], 'areas': [151], 'displayed': [152], 'hypertrophic': [153], 'hyperplastic': [155], 'astrocytosis.': [156], 'No': [157], 'significant': [158], 'effect': [159], 'on': [160], 'invasion': [162], 'detected': [164], 'at': [165], 'any': [166], 'time': [168], 'point': [169], '(0,': [170], '3,': [171], '5,': [172], '7': [174], 'weeks).': [175], 'We': [176], 'conclude': [177], 'that': [178], 'cuprizone‐induced': [179], 'provides': [181], 'adequate': [183], 'investigate': [187], 'therapy': [189], 'strategies': [190], 'prevention': [193], 'demyelination.': [196], '©': [197], '2008': [198], 'Wiley‐Liss,': [199], 'Inc.': [200]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2163640310', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-28T07:27:03.637133', 'created_date': '2016-06-24'}