Title: Two Cases of the Nephrotic Syndrome Associated with the Unilateral Renal Vein Thrombosis
Abstract: The unilateral renal vein thrombosis is often associated with the nephrotic syndrome demonstrating histologic findings similar to the membraneous or membrano-proliferative glomerulonephritis. Most studies have suggested that the renal vein thrombosis may be a complication of the nephrotic syndrome, which has been induced by its hypercoagulable state rather than its cause. However, others suppose that the unilateral renal vein thrombosis is an initial event and the membraneous glomerulonephritis is due to the immunologic injuries of glomeruli induced by the renal vein thrombosis. Two cases of the nephrotic syndrome associated with the unilateral renal vein thrombosis have been reported. Case 1 was a 48 year old female. She had the Sjögren's syndrome. She had the left renal vein thrombosis associated with the nephrotic syndrome but no hypercoagulable state. The immunofluorescent studies on kidey biopsy specimens demonstrated the presence of the immune complex nephritis. Case 2 was a 31 year old male. He had the nephrotic syndrome associated with the left renal vein thrombosis and the myocardial infarction. He had a hypercoagulable state. Histological examinations of kidney biopsy specimens revealed the minimal change lesions and no depositions of IgG and β1C were demonstrated by immunofluorescence.