Title: Dydrogesterone support in threatened miscarriage
Abstract: Introduction The aim of this study was to determine whether dydrogesterone helps to preserve pregnancy in women with threatened miscarriage. Methods 146 women who presented with mild or moderate vaginal bleeding during the first trimester of pregnancy were randomised to receive oral dydrogesterone (10 mg b.i.d.) (n = 86) or no treatment (n = 60). Dydrogesterone was continued until 1 week after the bleeding had stopped. All women received standard supportive care. Results The incidence of miscarriage was significantly lower in the dydrogesterone group than in the untreated group (17.5% vs. 25%; p < 0.05). There were no statistically significant differences between the groups with respect to pregnancy complications or congenital abnormalities. Conclusion Dydrogesterone appears to have beneficial effects in women with threatened miscarriage.
Publication Year: 2009
Publication Date: 2009-12-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 76
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