Title: Debaryomyces hansenii L2-enriched diet enhances the immunity status, gene expression and intestine functionality in gilthead seabream (Sparus aurata L.)
Abstract: This study evaluates the effects of the dietary administration of the live yeast Debaryomyces hansenii strain L2 on the immune responses of gilthead seabream for 4 weeks. Cellular immune parameters were measured from serum and head-kidney leucocytes respectively. The expression levels of immune-associated genes were quantified by real-time polymerase chain reaction. In addition, the profile of intestinal microbiota was studied by denaturing gradient gel electrophoresis. The results showed that seabream fed a diet containing D. hansenii had significantly increased cellular immune parameters. The yeast-supplemented diet up-regulated the expression of most seabream genes at week 2 and down-regulated all of them at week 4, except in the head-kidney. Finally, a reduction in the diversity of the intestinal microbiota was detected in those specimens receiving the yeast-supplemented diet. These results support the idea that the live yeast D. hansenii strain L2 stimulates the immune system of gilthead seabream.
Publication Year: 2011
Publication Date: 2011-07-05
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 28
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