Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2160775085', 'doi': 'https://doi.org/10.1146/annurev-biochem-060713-035324', 'title': 'Lipidomics: Analysis of the Lipid Composition of Cells and Subcellular Organelles by Electrospray Ionization Mass Spectrometry', 'display_name': 'Lipidomics: Analysis of the Lipid Composition of Cells and Subcellular Organelles by Electrospray Ionization Mass Spectrometry', 'publication_year': 2014, 'publication_date': '2014-03-08', 'ids': {'openalex': 'https://openalex.org/W2160775085', 'doi': 'https://doi.org/10.1146/annurev-biochem-060713-035324', 'mag': '2160775085', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24606142'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1146/annurev-biochem-060713-035324', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53860259', 'display_name': 'Annual Review of Biochemistry', 'issn_l': '0066-4154', 'issn': ['0066-4154', '1545-4509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320373', 'host_organization_name': 'Annual Reviews', 'host_organization_lineage': ['https://openalex.org/P4310320373'], 'host_organization_lineage_names': ['Annual Reviews'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5112377122', 'display_name': 'Britta Brügger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Britta Brügger', 'raw_affiliation_strings': ['Heidelberg University Biochemistry Center (BZH), 69120 Heidelberg, Germany;'], 'affiliations': [{'raw_affiliation_string': 'Heidelberg University Biochemistry Center (BZH), 69120 Heidelberg, Germany;', 'institution_ids': ['https://openalex.org/I223822909']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5112377122'], 'corresponding_institution_ids': ['https://openalex.org/I223822909'], 'apc_list': None, 'apc_paid': None, 'fwci': 2.632, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 253, 'citation_normalized_percentile': {'value': 0.992933, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '83', 'issue': '1', 'first_page': '79', 'last_page': '98'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques and Applications', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques and Applications', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10836', 'display_name': 'Metabolomics and Mass Spectrometry Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11844', 'display_name': 'Lipid metabolism and biosynthesis', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/organelle', 'display_name': 'Organelle', 'score': 0.6037694}, {'id': 'https://openalex.org/keywords/extractive-electrospray-ionization', 'display_name': 'Extractive electrospray ionization', 'score': 0.5773329}, {'id': 'https://openalex.org/keywords/lipidome', 'display_name': 'Lipidome', 'score': 0.45195407}], 'concepts': [{'id': 'https://openalex.org/C58017582', 'wikidata': 'https://www.wikidata.org/wiki/Q6556376', 'display_name': 'Lipidomics', 'level': 2, 'score': 0.89602995}, {'id': 'https://openalex.org/C40684141', 'wikidata': 'https://www.wikidata.org/wiki/Q902061', 'display_name': 'Electrospray ionization', 'level': 3, 'score': 0.702084}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.65854466}, {'id': 'https://openalex.org/C162356407', 'wikidata': 'https://www.wikidata.org/wiki/Q180809', 'display_name': 'Mass spectrometry', 'level': 2, 'score': 0.6395639}, {'id': 'https://openalex.org/C168240541', 'wikidata': 'https://www.wikidata.org/wiki/Q45948', 'display_name': 'Organelle', 'level': 2, 'score': 0.6037694}, {'id': 'https://openalex.org/C75233609', 'wikidata': 'https://www.wikidata.org/wiki/Q5422190', 'display_name': 'Extractive electrospray ionization', 'level': 5, 'score': 0.5773329}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.5190854}, {'id': 'https://openalex.org/C2780241833', 'wikidata': 'https://www.wikidata.org/wiki/Q6556375', 'display_name': 'Lipidome', 'level': 3, 'score': 0.45195407}, {'id': 'https://openalex.org/C40231798', 'wikidata': 'https://www.wikidata.org/wiki/Q1333743', 'display_name': 'Composition (language)', 'level': 2, 'score': 0.44283274}, {'id': 'https://openalex.org/C202157981', 'wikidata': 'https://www.wikidata.org/wiki/Q7251488', 'display_name': 'Protein mass spectrometry', 'level': 4, 'score': 0.3827719}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.30115128}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D008055', 'descriptor_name': 'Lipids', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D021241', 'descriptor_name': 'Spectrometry, Mass, Electrospray Ionization', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002308', 'descriptor_name': 'Cardiolipins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002308', 'descriptor_name': 'Cardiolipins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002627', 'descriptor_name': 'Chemistry, Physical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019295', 'descriptor_name': 'Computational Biology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008055', 'descriptor_name': 'Lipids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015388', 'descriptor_name': 'Organelles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015388', 'descriptor_name': 'Organelles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012997', 'descriptor_name': 'Solvents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012997', 'descriptor_name': 'Solvents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D021241', 'descriptor_name': 'Spectrometry, Mass, Electrospray Ionization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1146/annurev-biochem-060713-035324', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53860259', 'display_name': 'Annual Review of Biochemistry', 'issn_l': '0066-4154', 'issn': ['0066-4154', '1545-4509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320373', 'host_organization_name': 'Annual Reviews', 'host_organization_lineage': ['https://openalex.org/P4310320373'], 'host_organization_lineage_names': ['Annual Reviews'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24606142', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.44, 'display_name': 'Life on land', 'id': 'https://metadata.un.org/sdg/15'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 143, 'referenced_works': ['https://openalex.org/W1555054913', 'https://openalex.org/W1569454591', 'https://openalex.org/W1585562280', 'https://openalex.org/W1587539418', 'https://openalex.org/W164569191', 'https://openalex.org/W1808583155', 'https://openalex.org/W1890757015', 'https://openalex.org/W1964480443', 'https://openalex.org/W1964598018', 'https://openalex.org/W1965779137', 'https://openalex.org/W1967324781', 'https://openalex.org/W1968072363', 'https://openalex.org/W1969461041', 'https://openalex.org/W1969770915', 'https://openalex.org/W1970395441', 'https://openalex.org/W1972262472', 'https://openalex.org/W1974282614', 'https://openalex.org/W1975783279', 'https://openalex.org/W1977221909', 'https://openalex.org/W1981926613', 'https://openalex.org/W1982555544', 'https://openalex.org/W1983266711', 'https://openalex.org/W1983741550', 'https://openalex.org/W1984630839', 'https://openalex.org/W1984954439', 'https://openalex.org/W1986274674', 'https://openalex.org/W1986477156', 'https://openalex.org/W1988359982', 'https://openalex.org/W1988661228', 'https://openalex.org/W1988665826', 'https://openalex.org/W1988886825', 'https://openalex.org/W1989378845', 'https://openalex.org/W1995272207', 'https://openalex.org/W1997243317', 'https://openalex.org/W1998699136', 'https://openalex.org/W2000983103', 'https://openalex.org/W2001934773', 'https://openalex.org/W2004421311', 'https://openalex.org/W2006767554', 'https://openalex.org/W2007924265', 'https://openalex.org/W2009453329', 'https://openalex.org/W2011078603', 'https://openalex.org/W2011195483', 'https://openalex.org/W2015643261', 'https://openalex.org/W2015675759', 'https://openalex.org/W2016572177', 'https://openalex.org/W2017109633', 'https://openalex.org/W2017770030', 'https://openalex.org/W2018176211', 'https://openalex.org/W2020271697', 'https://openalex.org/W2022787379', 'https://openalex.org/W2024062720', 'https://openalex.org/W2024609981', 'https://openalex.org/W2026190396', 'https://openalex.org/W2027030291', 'https://openalex.org/W2029835453', 'https://openalex.org/W2029997837', 'https://openalex.org/W2034954688', 'https://openalex.org/W2037320975', 'https://openalex.org/W2037833102', 'https://openalex.org/W2042184375', 'https://openalex.org/W2043458312', 'https://openalex.org/W2043775257', 'https://openalex.org/W2044075316', 'https://openalex.org/W2045144594', 'https://openalex.org/W2048645427', 'https://openalex.org/W2048856163', 'https://openalex.org/W2049190436', 'https://openalex.org/W2052454481', 'https://openalex.org/W2053254030', 'https://openalex.org/W2054241405', 'https://openalex.org/W2055167993', 'https://openalex.org/W2056189730', 'https://openalex.org/W2059544508', 'https://openalex.org/W2066385795', 'https://openalex.org/W2068880228', 'https://openalex.org/W2070903093', 'https://openalex.org/W2070958222', 'https://openalex.org/W2071796811', 'https://openalex.org/W2072384875', 'https://openalex.org/W2072672665', 'https://openalex.org/W2073292063', 'https://openalex.org/W2074619822', 'https://openalex.org/W2074972538', 'https://openalex.org/W2077727777', 'https://openalex.org/W2079325827', 'https://openalex.org/W2079435449', 'https://openalex.org/W2081618928', 'https://openalex.org/W2082009865', 'https://openalex.org/W2087431894', 'https://openalex.org/W2087839268', 'https://openalex.org/W2089122504', 'https://openalex.org/W2089780431', 'https://openalex.org/W2092058086', 'https://openalex.org/W2093020484', 'https://openalex.org/W2095535218', 'https://openalex.org/W2098083113', 'https://openalex.org/W2103292401', 'https://openalex.org/W2104372768', 'https://openalex.org/W2104514258', 'https://openalex.org/W2106062306', 'https://openalex.org/W2106412980', 'https://openalex.org/W2107814511', 'https://openalex.org/W2111187697', 'https://openalex.org/W2116687544', 'https://openalex.org/W2118524679', 'https://openalex.org/W2119429228', 'https://openalex.org/W2119764013', 'https://openalex.org/W2126089474', 'https://openalex.org/W2127031535', 'https://openalex.org/W2128817061', 'https://openalex.org/W2131402057', 'https://openalex.org/W2134866108', 'https://openalex.org/W2135177750', 'https://openalex.org/W2135592618', 'https://openalex.org/W2136242062', 'https://openalex.org/W2139076333', 'https://openalex.org/W2141554292', 'https://openalex.org/W2144447780', 'https://openalex.org/W2146367740', 'https://openalex.org/W2147621341', 'https://openalex.org/W2148767345', 'https://openalex.org/W2149136509', 'https://openalex.org/W2149329792', 'https://openalex.org/W2149691867', 'https://openalex.org/W2150635383', 'https://openalex.org/W2151156336', 'https://openalex.org/W2152311269', 'https://openalex.org/W2154159866', 'https://openalex.org/W2154262768', 'https://openalex.org/W2157240187', 'https://openalex.org/W2157388299', 'https://openalex.org/W2158138282', 'https://openalex.org/W2158158759', 'https://openalex.org/W2165009222', 'https://openalex.org/W2166628970', 'https://openalex.org/W2167376541', 'https://openalex.org/W2168526937', 'https://openalex.org/W2300552860', 'https://openalex.org/W2335725835', 'https://openalex.org/W2412442244', 'https://openalex.org/W2412650844', 'https://openalex.org/W49360248'], 'related_works': ['https://openalex.org/W594333660', 'https://openalex.org/W4317479263', 'https://openalex.org/W4248445944', 'https://openalex.org/W3207725197', 'https://openalex.org/W2986402841', 'https://openalex.org/W2768723747', 'https://openalex.org/W2732317838', 'https://openalex.org/W2087839268', 'https://openalex.org/W2004863300', 'https://openalex.org/W1995155492'], 'abstract_inverted_index': {'Lipidomics': [0, 14], 'aims': [1], 'to': [2, 71, 89], 'quantitatively': [3, 90], 'define': [4], 'lipid': [5, 32, 92], 'classes,': [6], 'including': [7], 'their': [8], 'molecular': [9], 'species,': [10], 'in': [11, 25, 112], 'biological': [12, 115], 'systems.': [13], 'has': [15], 'experienced': [16], 'rapid': [17], 'progress,': [18], 'mainly': [19], 'because': [20], 'of': [21, 38, 45, 51, 58, 74, 94, 105, 108], 'continuous': [22], 'technical': [23], 'advances': [24], 'instrumentation': [26], 'that': [27], 'are': [28, 68], 'now': [29], 'enabling': [30], 'quantitative': [31], 'analyses': [33], 'with': [34, 54], 'an': [35], 'unprecedented': [36], 'level': [37], 'sensitivity': [39], 'and': [40, 66, 86, 96], 'precision.': [41], 'The': [42], 'still-growing': [43], 'category': [44], 'lipids': [46], 'includes': [47], 'a': [48, 55, 102], 'broad': [49], 'diversity': [50], 'chemical': [52], 'structures': [53], 'wide': [56], 'range': [57], 'physicochemical': [59], 'properties.': [60], 'Reflecting': [61], 'this': [62], 'diversity,': [63], 'different': [64], 'methods': [65], 'strategies': [67], 'being': [69], 'applied': [70], 'the': [72, 106], 'quantification': [73], 'lipids.': [75], 'Here,': [76], 'I': [77, 100], 'review': [78], 'state-of-the-art': [79], 'electrospray': [80], 'ionization': [81], 'tandem': [82], 'mass': [83, 109], 'spectrometric': [84], 'approaches': [85], 'direct': [87], 'infusion': [88], 'assess': [91], 'compositions': [93], 'cells': [95], 'subcellular': [97], 'fractions.': [98], 'Finally,': [99], 'discuss': [101], 'few': [103], 'examples': [104], 'power': [107], 'spectrometry-based': [110], 'lipidomics': [111], 'addressing': [113], 'cell': [114], 'questions.': [116]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2160775085', 'counts_by_year': [{'year': 2024, 'cited_by_count': 15}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 27}, {'year': 2020, 'cited_by_count': 30}, {'year': 2019, 'cited_by_count': 37}, {'year': 2018, 'cited_by_count': 29}, {'year': 2017, 'cited_by_count': 25}, {'year': 2016, 'cited_by_count': 27}, {'year': 2015, 'cited_by_count': 23}, {'year': 2014, 'cited_by_count': 5}], 'updated_date': '2024-12-15T20:06:57.709923', 'created_date': '2016-06-24'}