Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2160464112', 'doi': 'https://doi.org/10.1128/jcm.00785-13', 'title': 'Comparison of Pyrosequencing, Sanger Sequencing, and Melting Curve Analysis for Detection of Low-Frequency Macrolide-Resistant Mycoplasma pneumoniae Quasispecies in Respiratory Specimens', 'display_name': 'Comparison of Pyrosequencing, Sanger Sequencing, and Melting Curve Analysis for Detection of Low-Frequency Macrolide-Resistant Mycoplasma pneumoniae Quasispecies in Respiratory Specimens', 'publication_year': 2013, 'publication_date': '2013-08-01', 'ids': {'openalex': 'https://openalex.org/W2160464112', 'doi': 'https://doi.org/10.1128/jcm.00785-13', 'mag': '2160464112', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23720793', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3719661'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jcm.00785-13', 'pdf_url': 'https://jcm.asm.org/content/jcm/51/8/2592.full.pdf', 'source': {'id': 'https://openalex.org/S53087977', 'display_name': 'Journal of Clinical Microbiology', 'issn_l': '0095-1137', 'issn': ['0095-1137', '1070-633X', '1098-660X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://jcm.asm.org/content/jcm/51/8/2592.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5075755208', 'display_name': 'Kwok‐Hung Chan', 'orcid': 'https://orcid.org/0000-0003-1771-8249'}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Kwok-Hung Chan', 'raw_affiliation_strings': ['Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024396216', 'display_name': 'Kelvin Kai‐Wang To', 'orcid': 'https://orcid.org/0000-0002-1921-5824'}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Kelvin K. W. To', 'raw_affiliation_strings': ['Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'Research Centre of Infection and Immunology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Research Centre of Infection and Immunology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008903272', 'display_name': 'Betsy W. K. Chan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Betsy W. K. Chan', 'raw_affiliation_strings': ['Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035318435', 'display_name': 'Clara P. Y. Li', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Clara P. Y. Li', 'raw_affiliation_strings': ['Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005235378', 'display_name': 'Susan S. Chiu', 'orcid': 'https://orcid.org/0000-0002-3908-1974'}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Susan S. Chiu', 'raw_affiliation_strings': ['Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074675036', 'display_name': 'Kwok‐Yung Yuen', 'orcid': 'https://orcid.org/0000-0002-2083-1552'}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Kwok-Yung Yuen', 'raw_affiliation_strings': ['Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'Research Centre of Infection and Immunology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Research Centre of Infection and Immunology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5040618269', 'display_name': 'Pak‐Leung Ho', 'orcid': 'https://orcid.org/0000-0002-8811-1308'}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Pak-Leung Ho', 'raw_affiliation_strings': ['Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'Research Centre of Infection and Immunology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Research Centre of Infection and Immunology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}, {'raw_affiliation_string': 'Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China', 'institution_ids': ['https://openalex.org/I889458895']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.009, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 27, 'citation_normalized_percentile': {'value': 0.931775, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '51', 'issue': '8', 'first_page': '2592', 'last_page': '2598'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10654', 'display_name': 'Management and Epidemiology of Pneumonia', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10654', 'display_name': 'Management and Epidemiology of Pneumonia', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11688', 'display_name': 'Bacterial Pathogenesis in Animal and Human Health', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10873', 'display_name': 'Epidemiology and Pathogenesis of Bacterial Meningitis', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/viral-quasispecies', 'display_name': 'Viral quasispecies', 'score': 0.96117544}, {'id': 'https://openalex.org/keywords/sanger-sequencing', 'display_name': 'Sanger sequencing', 'score': 0.95365334}, {'id': 'https://openalex.org/keywords/pyrosequencing', 'display_name': 'Pyrosequencing', 'score': 0.936934}, {'id': 'https://openalex.org/keywords/melting-curve-analysis', 'display_name': 'Melting curve analysis', 'score': 0.5253008}, {'id': 'https://openalex.org/keywords/mycoplasma', 'display_name': 'Mycoplasma', 'score': 0.453155}], 'concepts': [{'id': 'https://openalex.org/C14500911', 'wikidata': 'https://www.wikidata.org/wiki/Q3413375', 'display_name': 'Viral quasispecies', 'level': 4, 'score': 0.96117544}, {'id': 'https://openalex.org/C76818968', 'wikidata': 'https://www.wikidata.org/wiki/Q181940', 'display_name': 'Sanger sequencing', 'level': 4, 'score': 0.95365334}, {'id': 'https://openalex.org/C125009961', 'wikidata': 'https://www.wikidata.org/wiki/Q2342248', 'display_name': 'Pyrosequencing', 'level': 3, 'score': 0.936934}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.71910226}, {'id': 'https://openalex.org/C2779215961', 'wikidata': 'https://www.wikidata.org/wiki/Q310904', 'display_name': 'Mycoplasma pneumoniae', 'level': 3, 'score': 0.6266484}, {'id': 'https://openalex.org/C84133368', 'wikidata': 'https://www.wikidata.org/wiki/Q6813768', 'display_name': 'Melting curve analysis', 'level': 4, 'score': 0.5253008}, {'id': 'https://openalex.org/C51679486', 'wikidata': 'https://www.wikidata.org/wiki/Q380546', 'display_name': 'DNA sequencing', 'level': 3, 'score': 0.45700634}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.43930146}, {'id': 'https://openalex.org/C49105822', 'wikidata': 'https://www.wikidata.org/wiki/Q176996', 'display_name': 'Polymerase chain reaction', 'level': 3, 'score': 0.35942167}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.32840744}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.32607377}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.20139816}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.11786416}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.091750056}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.061262935}, {'id': 'https://openalex.org/C2777914695', 'wikidata': 'https://www.wikidata.org/wiki/Q12192', 'display_name': 'Pneumonia', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2776408679', 'wikidata': 'https://www.wikidata.org/wiki/Q708693', 'display_name': 'Hepatitis C virus', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D024881', 'descriptor_name': 'Drug Resistance, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018942', 'descriptor_name': 'Macrolides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D009177', 'descriptor_name': 'Mycoplasma pneumoniae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D044366', 'descriptor_name': 'Transition Temperature', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004275', 'descriptor_name': 'DNA, Ribosomal', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D004275', 'descriptor_name': 'DNA, Ribosomal', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004275', 'descriptor_name': 'DNA, Ribosomal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018942', 'descriptor_name': 'Macrolides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009177', 'descriptor_name': 'Mycoplasma pneumoniae', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009177', 'descriptor_name': 'Mycoplasma pneumoniae', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D009177', 'descriptor_name': 'Mycoplasma pneumoniae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011019', 'descriptor_name': 'Pneumonia, Mycoplasma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011019', 'descriptor_name': 'Pneumonia, Mycoplasma', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jcm.00785-13', 'pdf_url': 'https://jcm.asm.org/content/jcm/51/8/2592.full.pdf', 'source': {'id': 'https://openalex.org/S53087977', 'display_name': 'Journal of Clinical Microbiology', 'issn_l': '0095-1137', 'issn': ['0095-1137', '1070-633X', '1098-660X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3719661', 'pdf_url': 'https://europepmc.org/articles/pmc3719661?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719661', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23720793', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jcm.00785-13', 'pdf_url': 'https://jcm.asm.org/content/jcm/51/8/2592.full.pdf', 'source': {'id': 'https://openalex.org/S53087977', 'display_name': 'Journal of Clinical Microbiology', 'issn_l': '0095-1137', 'issn': ['0095-1137', '1070-633X', '1098-660X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.67, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W149336651', 'https://openalex.org/W1757145451', 'https://openalex.org/W1964402677', 'https://openalex.org/W1967305082', 'https://openalex.org/W1970012514', 'https://openalex.org/W1973461089', 'https://openalex.org/W1974257388', 'https://openalex.org/W1977559696', 'https://openalex.org/W1988795407', 'https://openalex.org/W1993802862', 'https://openalex.org/W2004963563', 'https://openalex.org/W2005490754', 'https://openalex.org/W2006938589', 'https://openalex.org/W2012575234', 'https://openalex.org/W2018680667', 'https://openalex.org/W2019523835', 'https://openalex.org/W2060421888', 'https://openalex.org/W2060820177', 'https://openalex.org/W2065899164', 'https://openalex.org/W2072980776', 'https://openalex.org/W2083627256', 'https://openalex.org/W2096418370', 'https://openalex.org/W2098294680', 'https://openalex.org/W2098990854', 'https://openalex.org/W2105795595', 'https://openalex.org/W2109226805', 'https://openalex.org/W2114786387', 'https://openalex.org/W2117363503', 'https://openalex.org/W2119307837', 'https://openalex.org/W2119446608', 'https://openalex.org/W2121943744', 'https://openalex.org/W2127233477', 'https://openalex.org/W2130924724', 'https://openalex.org/W2133663415', 'https://openalex.org/W2134314196', 'https://openalex.org/W2135452247', 'https://openalex.org/W2136167339', 'https://openalex.org/W2136732990', 'https://openalex.org/W2148331516', 'https://openalex.org/W2152556112', 'https://openalex.org/W2152999502', 'https://openalex.org/W2160218755', 'https://openalex.org/W2163593399', 'https://openalex.org/W2165053145', 'https://openalex.org/W2165306143', 'https://openalex.org/W2166785990', 'https://openalex.org/W2167740716', 'https://openalex.org/W2417338971', 'https://openalex.org/W2486541549', 'https://openalex.org/W27875946'], 'related_works': ['https://openalex.org/W2472738690', 'https://openalex.org/W2413853260', 'https://openalex.org/W2349520025', 'https://openalex.org/W2226596076', 'https://openalex.org/W2160464112', 'https://openalex.org/W2152215405', 'https://openalex.org/W2086729134', 'https://openalex.org/W2024880418', 'https://openalex.org/W2001808934', 'https://openalex.org/W1970852420'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Macrolide-resistant': [1], 'Mycoplasma': [2], 'pneumoniae': [3, 71, 216], '(MRMP)': [4], 'is': [5], 'emerging': [6], 'worldwide': [7], 'and': [8, 29, 40, 55, 65, 132, 233, 238], 'has': [9], 'been': [10], 'associated': [11], 'with': [12, 34, 44, 104, 199, 229, 234], 'treatment': [13], 'failure.': [14], 'In': [15], 'this': [16], 'study,': [17], 'we': [18, 30], 'used': [19], 'pyrosequencing': [20, 56, 110], 'to': [21, 113, 142, 156, 212], 'detect': [22], 'low-frequency': [23], 'MRMP': [24, 89, 139, 195, 200], 'quasispecies': [25, 90, 107, 116, 140, 224], 'in': [26, 92], 'respiratory': [27], 'specimens,': [28, 73], 'compared': [31], 'the': [32, 69, 82, 96, 105, 179, 190], 'findings': [33], 'those': [35, 145, 152], 'obtained': [36, 236], 'by': [37, 109, 117, 129, 151, 172, 189, 202], 'Sanger': [38, 51, 118, 133, 173, 203], 'sequencing': [39, 119, 134, 204], 'SimpleProbe': [41, 53, 121, 130, 158], 'PCR': [42, 131, 159], 'coupled': [43], 'a': [45, 208], 'melting': [46], 'curve': [47], 'analysis': [48], '(SimpleProbe': [49], 'PCR).': [50], 'sequencing,': [52], 'PCR,': [54], 'were': [57, 111, 165, 181, 187], 'successfully': [58], 'performed': [59], 'for': [60], '96.7%': [61, 63], '(88/91),': [62, 64], '93.4%': [66], '(85/91)': [67], 'of': [68, 95, 101, 138, 178, 194, 222], 'M.': [70, 215], '-positive': [72], 'respectively.': [74], 'The': [75, 123, 175, 219], 'A-to-G': [76], 'transition': [77], 'at': [78], 'position': [79], '2063': [80], 'was': [81], 'only': [83], 'mutation': [84], 'identified.': [85], 'Pyrosequencing': [86], 'identified': [87, 166, 201], 'A2063G': [88, 106, 115], 'populations': [91, 232], '78.8%': [93], '(67/88)': [94], 'specimens.': [97], 'Only': [98], '38.8%': [99], '(26/67)': [100], 'these': [102], 'specimens': [103, 124, 163, 235], 'detected': [108, 128, 150], 'found': [112], 'be': [114, 127, 149, 226], 'or': [120, 170, 192], 'PCR.': [122], 'that': [125, 146, 164], 'could': [126, 147], 'had': [135], 'higher': [136], 'frequencies': [137], '(51%': [141], '100%)': [143], 'than': [144], 'not': [148, 182], 'two': [153], 'methods': [154], '(1%': [155], '44%).': [157], 'correctly': [160], 'categorized': [161], 'all': [162], 'as': [167], 'wild': [168], 'type': [169], 'mutant': [171, 223], 'sequencing.': [174], 'clinical': [176, 220], 'characteristics': [177], 'patients': [180, 198], 'significantly': [183], 'different': [184], 'when': [185], 'they': [186], 'grouped': [188], 'presence': [191], 'absence': [193], 'quasispecies,': [196], 'while': [197], 'more': [205], 'often': [206], 'required': [207], 'switch': [209], 'from': [210], 'macrolides': [211], 'an': [213], 'alternative': [214], '-targeted': [217], 'therapy.': [218, 241], 'significance': [221], 'should': [225], 'investigated': [227], 'further': [228], 'larger': [230], 'patient': [231], 'before': [237], 'after': [239], 'macrolide': [240]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2160464112', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-11T16:12:54.891672', 'created_date': '2016-06-24'}