Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2159534153', 'doi': 'https://doi.org/10.1242/dev.125.13.2381', 'title': '<i>Fgf8</i> is mutated in zebrafish <i>acerebellar</i> (<i>ace</i>) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesisy', 'display_name': '<i>Fgf8</i> is mutated in zebrafish <i>acerebellar</i> (<i>ace</i>) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesisy', 'publication_year': 1998, 'publication_date': '1998-07-01', 'ids': {'openalex': 'https://openalex.org/W2159534153', 'doi': 'https://doi.org/10.1242/dev.125.13.2381', 'mag': '2159534153', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9609821'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/dev.125.13.2381', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5072648742', 'display_name': 'Frank Reifers', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Frank Reifers', 'raw_affiliation_strings': ['University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany 1 Department of Neurobiology ,'], 'affiliations': [{'raw_affiliation_string': 'University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany 1 Department of Neurobiology ,', 'institution_ids': ['https://openalex.org/I223822909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062892008', 'display_name': 'Heike Böhli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Heike Böhli', 'raw_affiliation_strings': ['University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany 1 Department of Neurobiology ,'], 'affiliations': [{'raw_affiliation_string': 'University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany 1 Department of Neurobiology ,', 'institution_ids': ['https://openalex.org/I223822909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103832932', 'display_name': 'Emily C. Walsh', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Emily C. Walsh', 'raw_affiliation_strings': ['University of California San Francisco 2 Department of Biochemistry and Biophysics , , San Francisco, CA 94143-0554, USA'], 'affiliations': [{'raw_affiliation_string': 'University of California San Francisco 2 Department of Biochemistry and Biophysics , , San Francisco, CA 94143-0554, USA', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012511240', 'display_name': 'Philip H. Crossley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Phillip H. Crossley', 'raw_affiliation_strings': ['University of California San Francisco 2 Department of Biochemistry and Biophysics , , San Francisco, CA 94143-0554, USA'], 'affiliations': [{'raw_affiliation_string': 'University of California San Francisco 2 Department of Biochemistry and Biophysics , , San Francisco, CA 94143-0554, USA', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089780494', 'display_name': 'Didier Y. R. Stainier', 'orcid': 'https://orcid.org/0000-0002-0382-0026'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Didier Y. R. Stainier', 'raw_affiliation_strings': ['University of California San Francisco 2 Department of Biochemistry and Biophysics , , San Francisco, CA 94143-0554, USA'], 'affiliations': [{'raw_affiliation_string': 'University of California San Francisco 2 Department of Biochemistry and Biophysics , , San Francisco, CA 94143-0554, USA', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5050047419', 'display_name': 'Michael Brand', 'orcid': 'https://orcid.org/0000-0001-5711-6512'}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Michael Brand', 'raw_affiliation_strings': ['University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany 1 Department of Neurobiology ,'], 'affiliations': [{'raw_affiliation_string': 'University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany 1 Department of Neurobiology ,', 'institution_ids': ['https://openalex.org/I223822909']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 13.117, 'has_fulltext': False, 'cited_by_count': 691, 'citation_normalized_percentile': {'value': 0.999971, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '125', 'issue': '13', 'first_page': '2381', 'last_page': '2395'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11677', 'display_name': 'Molecular Mechanisms of Cardiac Development and Regeneration', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11677', 'display_name': 'Molecular Mechanisms of Cardiac Development and Regeneration', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10268', 'display_name': 'Notch Signaling Pathway in Development and Disease', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11685', 'display_name': 'Zebrafish as a Model Organism for Multidisciplinary Research', 'score': 0.9827, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/fgf8', 'display_name': 'FGF8', 'score': 0.9864043}, {'id': 'https://openalex.org/keywords/somitogenesis', 'display_name': 'Somitogenesis', 'score': 0.92675066}, {'id': 'https://openalex.org/keywords/hindbrain', 'display_name': 'Hindbrain', 'score': 0.8976803}, {'id': 'https://openalex.org/keywords/zebrafish', 'display_name': 'Zebrafish', 'score': 0.452258}], 'concepts': [{'id': 'https://openalex.org/C2776094402', 'wikidata': 'https://www.wikidata.org/wiki/Q17927891', 'display_name': 'FGF8', 'level': 4, 'score': 0.9864043}, {'id': 'https://openalex.org/C16693951', 'wikidata': 'https://www.wikidata.org/wiki/Q3489847', 'display_name': 'Somitogenesis', 'level': 5, 'score': 0.92675066}, {'id': 'https://openalex.org/C2777075493', 'wikidata': 'https://www.wikidata.org/wiki/Q1137072', 'display_name': 'Hindbrain', 'level': 3, 'score': 0.8976803}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.87809473}, {'id': 'https://openalex.org/C129536746', 'wikidata': 'https://www.wikidata.org/wiki/Q1141026', 'display_name': 'Gastrulation', 'level': 4, 'score': 0.86654925}, {'id': 'https://openalex.org/C2776878037', 'wikidata': 'https://www.wikidata.org/wiki/Q169444', 'display_name': 'Zebrafish', 'level': 3, 'score': 0.83520085}, {'id': 'https://openalex.org/C552161191', 'wikidata': 'https://www.wikidata.org/wiki/Q185080', 'display_name': 'Midbrain', 'level': 3, 'score': 0.60416126}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.5037355}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4986415}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.44145644}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.42970467}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.34753323}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.2497584}, {'id': 'https://openalex.org/C2779018604', 'wikidata': 'https://www.wikidata.org/wiki/Q1427600', 'display_name': 'Somite', 'level': 4, 'score': 0.22640023}, {'id': 'https://openalex.org/C74373430', 'wikidata': 'https://www.wikidata.org/wiki/Q24727126', 'display_name': 'Fibroblast growth factor', 'level': 3, 'score': 0.21014085}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.20245555}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17472193}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.06292829}], 'mesh': [{'descriptor_ui': 'D019521', 'descriptor_name': 'Body Patterning', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D005346', 'descriptor_name': 'Fibroblast Growth Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D005346', 'descriptor_name': 'Fibroblast Growth Factors', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001756', 'descriptor_name': 'Blastoderm', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001756', 'descriptor_name': 'Blastoderm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019521', 'descriptor_name': 'Body Patterning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000002', 'qualifier_name': 'abnormalities', 'is_major_topic': False}, {'descriptor_ui': 'D002531', 'descriptor_name': 'Cerebellum', 'qualifier_ui': 'Q000002', 'qualifier_name': 'abnormalities', 'is_major_topic': False}, {'descriptor_ui': 'D002531', 'descriptor_name': 'Cerebellum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002645', 'descriptor_name': 'Chickens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003433', 'descriptor_name': 'Crosses, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004627', 'descriptor_name': 'Embryonic Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004627', 'descriptor_name': 'Embryonic Induction', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051524', 'descriptor_name': 'Fibroblast Growth Factor 8', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005346', 'descriptor_name': 'Fibroblast Growth Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005346', 'descriptor_name': 'Fibroblast Growth Factors', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': False}, {'descriptor_ui': 'D005775', 'descriptor_name': 'Gastrula', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005775', 'descriptor_name': 'Gastrula', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006579', 'descriptor_name': 'Heterozygote', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015347', 'descriptor_name': 'RNA Probes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016415', 'descriptor_name': 'Sequence Alignment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017386', 'descriptor_name': 'Sequence Homology, Amino Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019170', 'descriptor_name': 'Somites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/dev.125.13.2381', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9609821', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.58, 'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 91, 'referenced_works': ['https://openalex.org/W1502842089', 'https://openalex.org/W1518312269', 'https://openalex.org/W170742439', 'https://openalex.org/W1773483894', 'https://openalex.org/W1811188705', 'https://openalex.org/W1851680357', 'https://openalex.org/W1854803455', 'https://openalex.org/W1859795936', 'https://openalex.org/W1869819849', 'https://openalex.org/W1871313898', 'https://openalex.org/W1888475523', 'https://openalex.org/W1907712000', 'https://openalex.org/W1922106993', 'https://openalex.org/W1932906170', 'https://openalex.org/W1961074127', 'https://openalex.org/W1963463566', 'https://openalex.org/W1964795153', 'https://openalex.org/W1965444020', 'https://openalex.org/W1967198448', 'https://openalex.org/W1967630734', 'https://openalex.org/W1972115003', 'https://openalex.org/W1972727772', 'https://openalex.org/W1976886867', 'https://openalex.org/W1977025966', 'https://openalex.org/W1977253322', 'https://openalex.org/W1978809889', 'https://openalex.org/W1980688235', 'https://openalex.org/W1985360296', 'https://openalex.org/W1992665853', 'https://openalex.org/W1993101422', 'https://openalex.org/W2002651590', 'https://openalex.org/W2005391395', 'https://openalex.org/W2005494875', 'https://openalex.org/W2006136865', 'https://openalex.org/W2010206624', 'https://openalex.org/W2010585318', 'https://openalex.org/W2011257584', 'https://openalex.org/W2017204222', 'https://openalex.org/W2017549518', 'https://openalex.org/W2022384673', 'https://openalex.org/W2032288446', 'https://openalex.org/W2032382800', 'https://openalex.org/W2033291406', 'https://openalex.org/W2056016311', 'https://openalex.org/W2058528119', 'https://openalex.org/W2059204642', 'https://openalex.org/W2061191160', 'https://openalex.org/W2062053824', 'https://openalex.org/W2063852715', 'https://openalex.org/W2065220482', 'https://openalex.org/W2068801415', 'https://openalex.org/W2069022895', 'https://openalex.org/W2072303535', 'https://openalex.org/W2073908723', 'https://openalex.org/W2074210550', 'https://openalex.org/W2077236080', 'https://openalex.org/W2077802746', 'https://openalex.org/W2090533250', 'https://openalex.org/W2090821553', 'https://openalex.org/W2092079816', 'https://openalex.org/W2092423326', 'https://openalex.org/W2094999649', 'https://openalex.org/W2096329642', 'https://openalex.org/W2099002558', 'https://openalex.org/W2102320296', 'https://openalex.org/W2107071468', 'https://openalex.org/W2110825450', 'https://openalex.org/W2111479560', 'https://openalex.org/W2118544547', 'https://openalex.org/W2119800709', 'https://openalex.org/W2120398270', 'https://openalex.org/W2125295969', 'https://openalex.org/W2125349610', 'https://openalex.org/W2127312018', 'https://openalex.org/W2138643777', 'https://openalex.org/W2148091108', 'https://openalex.org/W2164386538', 'https://openalex.org/W2170251919', 'https://openalex.org/W2172110892', 'https://openalex.org/W2181939690', 'https://openalex.org/W2183330297', 'https://openalex.org/W2184559181', 'https://openalex.org/W2188737084', 'https://openalex.org/W2285008745', 'https://openalex.org/W2345927070', 'https://openalex.org/W2403316467', 'https://openalex.org/W2409783973', 'https://openalex.org/W2444619274', 'https://openalex.org/W3021597811', 'https://openalex.org/W4246928882', 'https://openalex.org/W4254469900'], 'related_works': ['https://openalex.org/W2601198612', 'https://openalex.org/W2414258062', 'https://openalex.org/W2171521049', 'https://openalex.org/W2164655566', 'https://openalex.org/W2159534153', 'https://openalex.org/W2026613468', 'https://openalex.org/W2006136865', 'https://openalex.org/W1999118637', 'https://openalex.org/W1994751359', 'https://openalex.org/W1969897072'], 'abstract_inverted_index': {'ABSTRACT': [0], 'We': [1, 77], 'describe': [2], 'the': [3, 27, 30, 54, 119, 134, 166, 175, 182, 196], 'isolation': [4], 'of': [5, 29, 68, 95, 165, 190], 'zebrafish': [6, 39, 197], 'Fgf8': [7, 31, 40, 45, 58, 80, 96, 127, 136, 149, 171, 184], 'and': [8, 16, 24, 53, 70, 81, 93, 125, 146], 'its': [9], 'expression': [10, 67], 'during': [11, 123, 130, 144], 'gastrulation,': [12, 124], 'somitogenesis,': [13], 'fin': [14], 'bud': [15], 'early': [17], 'brain': [18], 'development.': [19], 'By': [20], 'demonstrating': [21], 'genetic': [22], 'linkage': [23], 'by': [25], 'analysing': [26], 'structure': [28], 'gene,': [32], 'we': [33], 'show': [34, 78, 156], 'that': [35, 42, 79, 88, 103, 111, 126], 'acerebellar': [36, 48, 154], 'is': [37, 60, 137, 185], 'a': [38, 51, 141], 'mutation': [41], 'may': [43, 200], 'inactivate': [44], 'function.': [46], 'Homozygous': [47], 'embryos': [49, 102], 'lack': [50], 'cerebellum': [52], 'midbrain-hindbrain': [55, 120], 'boundary': [56, 121], 'organizer.': [57], 'function': [59], 'required': [61, 187], 'to': [62, 132], 'maintain,': [63], 'but': [64, 199], 'not': [65], 'initiate,': [66], 'Pax2.1': [69, 82], 'other': [71], 'marker': [72], 'genes': [73], 'in': [74, 85, 99, 118, 140, 163, 172, 181, 188, 195], 'this': [75], 'area.': [76], 'are': [83, 104, 115, 178], 'activated': [84, 117], 'adjacent': [86], 'domains': [87], 'only': [89, 157], 'later': [90, 129], 'become': [91], 'overlapping,': [92], 'activation': [94], 'occurs': [97], 'normally': [98], 'no': [100], 'isthmus': [101], 'mutant': [105], 'for': [106, 170, 205], 'Pax2.1.': [107], 'These': [108], 'findings': [109], 'suggest': [110], 'multiple': [112], 'signaling': [113, 193], 'pathways': [114], 'independently': [116], 'primordium': [122], 'functions': [128], 'somitogenesis': [131], 'polarize': [133], 'midbrain.': [135], 'also': [138], 'expressed': [139, 148], 'dorsoventral': [142, 159], 'gradient': [143], 'gastrulation': [145], 'ectopically': [147], 'can': [150], 'dorsalize': [151], 'embryos.': [152], 'Nevertheless,': [153], 'mutants': [155], 'mild': [158], 'patterning': [160], 'defects.': [161], 'Also,': [162], 'spite': [164], 'prominent': [167], 'role': [168], 'suggested': [169], 'limb': [173], 'development,': [174], 'pectoral': [176], 'fins': [177], 'largely': [179], 'unaffected': [180], 'mutants.': [183], 'therefore': [186], 'development': [189], 'several': [191], 'important': [192], 'centers': [194], 'embryo,': [198], 'be': [201], 'redundant': [202], 'or': [203], 'dispensable': [204], 'others.': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2159534153', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 9}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 10}, {'year': 2020, 'cited_by_count': 17}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 19}, {'year': 2017, 'cited_by_count': 16}, {'year': 2016, 'cited_by_count': 13}, {'year': 2015, 'cited_by_count': 19}, {'year': 2014, 'cited_by_count': 22}, {'year': 2013, 'cited_by_count': 31}, {'year': 2012, 'cited_by_count': 23}], 'updated_date': '2024-09-17T16:47:23.562934', 'created_date': '2016-06-24'}