Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2159437534', 'doi': 'https://doi.org/10.1111/j.1600-079x.2009.00719.x', 'title': 'RETRACTED: Changes in the expression of melatonin receptors induced by melatonin treatment in hepatocarcinoma HepG2 cells', 'display_name': 'RETRACTED: Changes in the expression of melatonin receptors induced by melatonin treatment in hepatocarcinoma HepG2 cells', 'publication_year': 2009, 'publication_date': '2009-10-10', 'ids': {'openalex': 'https://openalex.org/W2159437534', 'doi': 'https://doi.org/10.1111/j.1600-079x.2009.00719.x', 'mag': '2159437534', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19817970'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1600-079x.2009.00719.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114728194', 'display_name': 'Journal of Pineal Research', 'issn_l': '0742-3098', 'issn': ['0742-3098', '1600-079X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5036229059', 'display_name': 'Sara Carbajo‐Pescador', 'orcid': 'https://orcid.org/0000-0002-6751-4597'}, 'institutions': [{'id': 'https://openalex.org/I4210132431', 'display_name': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas', 'ror': 'https://ror.org/03cn6tr16', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132431']}, {'id': 'https://openalex.org/I8833935', 'display_name': 'Universidad de León', 'ror': 'https://ror.org/02tzt0b78', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I8833935']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Sara Carbajo‐Pescador', 'raw_affiliation_strings': ['Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain'], 'affiliations': [{'raw_affiliation_string': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain', 'institution_ids': ['https://openalex.org/I4210132431', 'https://openalex.org/I8833935']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076215344', 'display_name': 'Javier Martín‐Renedo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210132431', 'display_name': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas', 'ror': 'https://ror.org/03cn6tr16', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132431']}, {'id': 'https://openalex.org/I8833935', 'display_name': 'Universidad de León', 'ror': 'https://ror.org/02tzt0b78', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I8833935']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Javier Martín‐Renedo', 'raw_affiliation_strings': ['Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain'], 'affiliations': [{'raw_affiliation_string': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain', 'institution_ids': ['https://openalex.org/I4210132431', 'https://openalex.org/I8833935']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039090336', 'display_name': 'Andrés García‐Palomo', 'orcid': 'https://orcid.org/0000-0002-9159-9025'}, 'institutions': [], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Andrés García‐Palomo', 'raw_affiliation_strings': ['Service of Oncology, Complejo Asistencial de León, León, Spain'], 'affiliations': [{'raw_affiliation_string': 'Service of Oncology, Complejo Asistencial de León, León, Spain', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042870785', 'display_name': 'María J. Tuñón', 'orcid': 'https://orcid.org/0000-0001-7827-5918'}, 'institutions': [{'id': 'https://openalex.org/I4210132431', 'display_name': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas', 'ror': 'https://ror.org/03cn6tr16', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132431']}, {'id': 'https://openalex.org/I8833935', 'display_name': 'Universidad de León', 'ror': 'https://ror.org/02tzt0b78', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I8833935']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'María J. Tuñón', 'raw_affiliation_strings': ['Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain'], 'affiliations': [{'raw_affiliation_string': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain', 'institution_ids': ['https://openalex.org/I4210132431', 'https://openalex.org/I8833935']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035398172', 'display_name': 'José L. Mauriz', 'orcid': 'https://orcid.org/0000-0003-3160-8599'}, 'institutions': [{'id': 'https://openalex.org/I4210132431', 'display_name': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas', 'ror': 'https://ror.org/03cn6tr16', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132431']}, {'id': 'https://openalex.org/I8833935', 'display_name': 'Universidad de León', 'ror': 'https://ror.org/02tzt0b78', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I8833935']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'José L. Mauriz', 'raw_affiliation_strings': ['Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain'], 'affiliations': [{'raw_affiliation_string': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain', 'institution_ids': ['https://openalex.org/I4210132431', 'https://openalex.org/I8833935']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5084567869', 'display_name': 'Javier González‐Gallego', 'orcid': 'https://orcid.org/0000-0002-4386-9342'}, 'institutions': [{'id': 'https://openalex.org/I4210132431', 'display_name': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas', 'ror': 'https://ror.org/03cn6tr16', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210132431']}, {'id': 'https://openalex.org/I8833935', 'display_name': 'Universidad de León', 'ror': 'https://ror.org/02tzt0b78', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I8833935']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Javier González‐Gallego', 'raw_affiliation_strings': ['Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain'], 'affiliations': [{'raw_affiliation_string': 'Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) and Institute of Biomedicine, University of León, León, Spain', 'institution_ids': ['https://openalex.org/I4210132431', 'https://openalex.org/I8833935']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4530, 'currency': 'USD', 'value_usd': 4530, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.274, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 46, 'citation_normalized_percentile': {'value': 0.886821, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '47', 'issue': '4', 'first_page': '330', 'last_page': '338'}, 'is_retracted': True, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10342', 'display_name': 'Circadian rhythm and melatonin', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10342', 'display_name': 'Circadian rhythm and melatonin', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2778182776', 'wikidata': 'https://www.wikidata.org/wiki/Q180912', 'display_name': 'Melatonin', 'level': 2, 'score': 0.9842703}, {'id': 'https://openalex.org/C2781269140', 'wikidata': 'https://www.wikidata.org/wiki/Q24784310', 'display_name': 'Melatonin receptor', 'level': 3, 'score': 0.8138372}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.68610823}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.6421119}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6367297}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5439768}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.5015321}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.48307064}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.47931778}, {'id': 'https://openalex.org/C63932345', 'wikidata': 'https://www.wikidata.org/wiki/Q422500', 'display_name': 'Nuclear receptor', 'level': 4, 'score': 0.41419733}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.23649076}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.08381978}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.053911656}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D008550', 'descriptor_name': 'Melatonin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044122', 'descriptor_name': 'Receptor, Melatonin, MT1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044123', 'descriptor_name': 'Receptor, Melatonin, MT2', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044094', 'descriptor_name': 'Receptors, Melatonin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020133', 'descriptor_name': 'Reverse Transcriptase Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1600-079x.2009.00719.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114728194', 'display_name': 'Journal of Pineal Research', 'issn_l': '0742-3098', 'issn': ['0742-3098', '1600-079X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19817970', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.81, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 66, 'referenced_works': ['https://openalex.org/W1543856977', 'https://openalex.org/W1629179716', 'https://openalex.org/W1656460628', 'https://openalex.org/W1945927531', 'https://openalex.org/W1964314898', 'https://openalex.org/W1971261522', 'https://openalex.org/W1972185917', 'https://openalex.org/W1974447083', 'https://openalex.org/W1975241900', 'https://openalex.org/W1978466903', 'https://openalex.org/W1983566539', 'https://openalex.org/W1991186732', 'https://openalex.org/W1994933445', 'https://openalex.org/W1998121995', 'https://openalex.org/W2002746961', 'https://openalex.org/W2009244828', 'https://openalex.org/W2011638807', 'https://openalex.org/W2012204755', 'https://openalex.org/W2012960060', 'https://openalex.org/W2017352677', 'https://openalex.org/W2019961689', 'https://openalex.org/W2020181071', 'https://openalex.org/W2021371462', 'https://openalex.org/W2025044870', 'https://openalex.org/W2025132816', 'https://openalex.org/W2026605955', 'https://openalex.org/W2027499519', 'https://openalex.org/W2028085265', 'https://openalex.org/W2031562023', 'https://openalex.org/W2033147224', 'https://openalex.org/W2034928061', 'https://openalex.org/W2034963335', 'https://openalex.org/W2047224082', 'https://openalex.org/W2047587215', 'https://openalex.org/W2057248051', 'https://openalex.org/W2062274317', 'https://openalex.org/W2069389572', 'https://openalex.org/W2069866574', 'https://openalex.org/W2076789904', 'https://openalex.org/W2083510568', 'https://openalex.org/W2084352422', 'https://openalex.org/W2084789130', 'https://openalex.org/W2086224879', 'https://openalex.org/W2093060455', 'https://openalex.org/W2094560884', 'https://openalex.org/W2098094265', 'https://openalex.org/W2107102357', 'https://openalex.org/W2107277218', 'https://openalex.org/W2110433560', 'https://openalex.org/W2120234752', 'https://openalex.org/W2120854324', 'https://openalex.org/W2135912670', 'https://openalex.org/W2145966572', 'https://openalex.org/W2149150530', 'https://openalex.org/W2150775371', 'https://openalex.org/W2155791164', 'https://openalex.org/W2156108044', 'https://openalex.org/W2165729917', 'https://openalex.org/W2167797983', 'https://openalex.org/W2170596902', 'https://openalex.org/W2274421275', 'https://openalex.org/W2402351661', 'https://openalex.org/W2437355544', 'https://openalex.org/W2472549011', 'https://openalex.org/W3021350529', 'https://openalex.org/W4240999623'], 'related_works': ['https://openalex.org/W4206018501', 'https://openalex.org/W2969654250', 'https://openalex.org/W2096715356', 'https://openalex.org/W2084352422', 'https://openalex.org/W2082186207', 'https://openalex.org/W2042910156', 'https://openalex.org/W2003400611', 'https://openalex.org/W1978208951', 'https://openalex.org/W1977214231', 'https://openalex.org/W1976493197'], 'abstract_inverted_index': {'Hepatocellular': [0], 'carcinoma': [1], '(HCC)': [2], 'is': [3, 13], 'one': [4], 'of': [5, 68, 79, 99, 154, 185, 209, 224, 245, 249], 'the': [6, 51, 63, 76, 80, 92, 97, 145, 152, 177, 207, 221, 243], 'most': [7], 'common': [8], 'cancers': [9], 'and': [10, 24, 65, 111, 121, 133, 162, 167, 188], 'its': [11, 86, 231], 'incidence': [12], 'increasing': [14], 'worldwide.': [15], 'Melatonin,': [16], 'an': [17, 142, 149], 'indoleamine': [18], 'hormone,': [19], 'exerts': [20], 'anti-oxidant,': [21], 'immunomodulatory,': [22], 'anti-aging,': [23], 'antitumor': [25, 222], 'effects.': [26], 'Previous': [27], 'studies': [28], 'have': [29, 58], 'shown': [30], 'that': [31, 230], 'melatonin': [32, 69, 82, 100, 112, 165, 196, 225], 'can': [33], 'act': [34], 'through': [35], 'specific': [36], 'receptors,': [37], 'including': [38], 'MT(1),': [39, 186], 'MT(2),': [40], 'MT(3)': [41], 'receptors': [42, 84], 'as': [43, 45], 'well': [44], 'a': [46, 131, 168, 203], 'nuclear': [47, 53], 'receptor': [48, 54, 113], 'belonging': [49], 'to': [50, 240], 'orphan': [52, 191], 'family.': [55], 'Recently,': [56], 'we': [57, 95], 'described': [59], 'their': [60, 246], 'role': [61, 78], 'in': [62, 144, 151, 156, 182, 206, 226, 238], 'oncostatic': [64, 232], 'pro-apoptotic': [66], 'effects': [67, 88], 'on': [70, 85, 102, 136, 171, 242], 'HepG2': [71, 103], 'human': [72, 104], 'HCC': [73, 105, 227], 'cells.': [74], 'However,': [75], 'potential': [77], 'different': [81, 247], 'cellular': [83], 'antiproliferative': [87], 'remains': [89], 'unknown.': [90], 'In': [91], 'present': [93], 'study,': [94], 'examined': [96], 'effect': [98, 223], 'treatment': [101, 140], 'cells,': [106, 228], 'analyzing': [107], 'cell': [108, 137, 146, 174, 215], 'cycle': [109, 216], 'arrest': [110], 'expression.': [114], 'Melatonin': [115, 129], 'was': [116], 'administered': [117], 'for': [118], '2,': [119], '4,': [120], '6': [122], 'days': [123], 'at': [124, 159, 236], '1000': [125, 161], 'or': [126], '2500': [127, 163], 'microm.': [128], 'induced': [130], 'dose-': [132], 'time-dependent': [134], 'inhibition': [135], 'proliferation.': [138], 'This': [139], 'caused': [141], 'alteration': [143], 'cycle,': [147], 'with': [148, 202], 'increase': [150, 170], 'number': [153], 'cells': [155], 'G(2)/M': [157], 'phase': [158, 173], 'both': [160], 'microm': [164], 'concentrations,': [166], 'significant': [169, 204], 'S': [172], 'percentage': [175], 'by': [176], 'highest': [178], 'dose.': [179], 'Furthermore,': [180], 'increases': [181, 199], 'protein': [183], 'expression': [184, 208, 244], 'MT(3),': [187], 'retinoic': [189], 'acid-related': [190], 'receptor-alpha': [192], 'were': [193, 200], 'found': [194], 'after': [195], 'treatments.': [197], 'These': [198], 'coincident': [201], 'induction': [205], 'p21': [210], 'protein,': [211], 'which': [212], 'negatively': [213], 'regulates': [214], 'progression.': [217], 'Our': [218], 'results': [219], 'confirm': [220], 'suggesting': [229], 'properties': [233], 'are': [234], 'related,': [235], 'least': [237], 'part,': [239], 'changes': [241], 'subtypes': [248], 'receptors.': [250]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2159437534', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-30T02:00:50.599489', 'created_date': '2016-06-24'}