Publication Information

{'id': 'https://openalex.org/W2159336227', 'doi': 'https://doi.org/10.1242/jcs.112.10.1477', 'title': 'The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment', 'display_name': 'The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment', 'publication_year': 1999, 'publication_date': '1999-05-15', 'ids': {'openalex': 'https://openalex.org/W2159336227', 'doi': 'https://doi.org/10.1242/jcs.112.10.1477', 'mag': '2159336227', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10212142'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/jcs.112.10.1477', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5061871754', 'display_name': 'Julie Greenfield', 'orcid': 'https://orcid.org/0000-0003-2876-4849'}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Julia J. A. Greenfield', 'raw_affiliation_strings': ['University of Manchester, 2.205 Stopford Building, Oxford Road School of Biological Sciences , , Manchester M13 9PT, UK'], 'affiliations': [{'raw_affiliation_string': 'University of Manchester, 2.205 Stopford Building, Oxford Road School of Biological Sciences , , Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068891892', 'display_name': 'Stephen High', 'orcid': 'https://orcid.org/0000-0002-4532-8152'}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Stephen High', 'raw_affiliation_strings': ['University of Manchester, 2.205 Stopford Building, Oxford Road School of Biological Sciences , , Manchester M13 9PT, UK'], 'affiliations': [{'raw_affiliation_string': 'University of Manchester, 2.205 Stopford Building, Oxford Road School of Biological Sciences , , Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.971, 'has_fulltext': False, 'cited_by_count': 123, 'citation_normalized_percentile': {'value': 0.999781, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '112', 'issue': '10', 'first_page': '1477', 'last_page': '1486'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12610', 'display_name': 'RNA regulation and disease', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10407', 'display_name': 'Lipid Membrane Structure and Behavior', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sec61', 'display_name': 'Sec61', 'score': 0.90858614}, {'id': 'https://openalex.org/keywords/cell-fractionation', 'display_name': 'Cell fractionation', 'score': 0.45520025}], 'concepts': [{'id': 'https://openalex.org/C113584667', 'wikidata': 'https://www.wikidata.org/wiki/Q16946673', 'display_name': 'Sec61', 'level': 5, 'score': 0.90858614}, {'id': 'https://openalex.org/C119062480', 'wikidata': 'https://www.wikidata.org/wiki/Q83181', 'display_name': 'Golgi apparatus', 'level': 3, 'score': 0.7255212}, {'id': 'https://openalex.org/C199229279', 'wikidata': 'https://www.wikidata.org/wiki/Q610647', 'display_name': 'Translocon', 'level': 4, 'score': 0.61129177}, {'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.58304596}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.57754236}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5326663}, {'id': 'https://openalex.org/C24530287', 'wikidata': 'https://www.wikidata.org/wiki/Q424204', 'display_name': 'Transmembrane protein', 'level': 3, 'score': 0.47095662}, {'id': 'https://openalex.org/C27239569', 'wikidata': 'https://www.wikidata.org/wiki/Q189029', 'display_name': 'Cell fractionation', 'level': 3, 'score': 0.45520025}, {'id': 'https://openalex.org/C98539663', 'wikidata': 'https://www.wikidata.org/wiki/Q220599', 'display_name': 'Cytosol', 'level': 3, 'score': 0.41703194}, {'id': 'https://openalex.org/C144647389', 'wikidata': 'https://www.wikidata.org/wiki/Q423042', 'display_name': 'Membrane protein', 'level': 3, 'score': 0.41120693}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.36119378}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25847384}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.21814844}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.09152332}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006056', 'descriptor_name': 'Golgi Apparatus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020126', 'descriptor_name': 'Brefeldin A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020126', 'descriptor_name': 'Brefeldin A', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D019556', 'descriptor_name': 'COS Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006056', 'descriptor_name': 'Golgi Apparatus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049452', 'descriptor_name': 'Green Fluorescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008164', 'descriptor_name': 'Luminescent Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008164', 'descriptor_name': 'Luminescent Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008856', 'descriptor_name': 'Microscopy, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011500', 'descriptor_name': 'Protein Synthesis Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011500', 'descriptor_name': 'Protein Synthesis Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000069816', 'descriptor_name': 'SEC Translocation Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/jcs.112.10.1477', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10212142', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life on land', 'id': 'https://metadata.un.org/sdg/15', 'score': 0.49}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W1497042513', 'https://openalex.org/W1499727792', 'https://openalex.org/W1607363788', 'https://openalex.org/W1852053696', 'https://openalex.org/W1852712855', 'https://openalex.org/W1972341173', 'https://openalex.org/W1976601347', 'https://openalex.org/W1982198203', 'https://openalex.org/W1983986068', 'https://openalex.org/W1991736711', 'https://openalex.org/W1998492766', 'https://openalex.org/W1998711108', 'https://openalex.org/W2003144507', 'https://openalex.org/W2007670768', 'https://openalex.org/W2016184277', 'https://openalex.org/W2017765863', 'https://openalex.org/W2026896701', 'https://openalex.org/W2029152767', 'https://openalex.org/W2029193330', 'https://openalex.org/W2030463413', 'https://openalex.org/W2031814212', 'https://openalex.org/W2036130921', 'https://openalex.org/W2045571454', 'https://openalex.org/W2052504607', 'https://openalex.org/W2054593368', 'https://openalex.org/W2058971645', 'https://openalex.org/W2064859908', 'https://openalex.org/W2065736462', 'https://openalex.org/W2069116829', 'https://openalex.org/W2071748696', 'https://openalex.org/W2075819285', 'https://openalex.org/W2079869381', 'https://openalex.org/W2082103548', 'https://openalex.org/W2083210641', 'https://openalex.org/W2087113665', 'https://openalex.org/W2087662274', 'https://openalex.org/W2088819006', 'https://openalex.org/W2099616208', 'https://openalex.org/W2102751763', 'https://openalex.org/W2103356759', 'https://openalex.org/W2104360518', 'https://openalex.org/W2107886504', 'https://openalex.org/W2118016880', 'https://openalex.org/W2120636641', 'https://openalex.org/W2142329004', 'https://openalex.org/W2157729659', 'https://openalex.org/W2158097661', 'https://openalex.org/W2167988140', 'https://openalex.org/W2168860268', 'https://openalex.org/W2409054733', 'https://openalex.org/W2412433213', 'https://openalex.org/W4248568661', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4394856260', 'https://openalex.org/W4394841675', 'https://openalex.org/W4390144315', 'https://openalex.org/W4323031742', 'https://openalex.org/W4298182251', 'https://openalex.org/W4292283928', 'https://openalex.org/W3081591791', 'https://openalex.org/W2999361287', 'https://openalex.org/W2093399201', 'https://openalex.org/W2012738583'], 'abstract_inverted_index': {'ABSTRACT': [0], 'The': [1, 143], 'heteromeric': [2], 'Sec61': [3, 25, 50, 147], 'complex': [4, 26, 51], 'is': [5], 'composed': [6], 'of': [7, 17, 23, 48, 91, 114, 140, 145, 170, 213], 'α,': [8], 'β': [9, 123], 'and': [10, 13, 36, 57, 77, 94, 107, 124, 126, 136, 161], 'γ': [11], 'subunits': [12, 148], 'forms': [14], 'the': [15, 18, 24, 39, 45, 49, 68, 75, 78, 86, 105, 108, 111, 134, 137, 141, 146, 159, 166, 193, 210, 214, 223, 232], 'core': [16, 211], 'mammalian': [19, 215], 'ER': [20, 40, 76, 106, 135, 160, 216, 233], 'translocon.': [21], 'Oligomers': [22], 'form': [27], 'a': [28, 150, 235], 'transmembrane': [29], 'channel': [30], 'where': [31], 'proteins': [32, 99, 156], 'are': [33, 100, 129, 218, 229], 'translocated': [34], 'across': [35], 'integrated': [37], 'into': [38], 'membrane.': [41], 'We': [42, 186], 'have': [43, 118], 'studied': [44], 'subcellular': [46, 115, 204], 'localisation': [47], 'using': [52], 'both': [53, 74, 104, 133], 'wild-type': [54, 121], 'COS1': [55], 'cells': [56, 58], 'transfected': [59], 'with': [60], 'GFP-tagged': [61, 69, 127], 'Sec61α.': [62], 'By': [63], 'double': [64], 'labelling': [65], 'immunofluorescence': [66], 'microscopy': [67], 'Sec61α': [70], 'was': [71, 196], 'found': [72, 188], 'in': [73, 85, 103, 132, 149, 198, 222, 231], 'ER-Golgi': [79], 'intermediate': [80], 'compartment': [81, 152], '(ERGIC)': [82], 'but': [83, 225], 'not': [84, 219], 'trans-Golgi': [87], 'network.': [88], 'Immunofluorescence': [89], 'studies': [90], 'endogenous': [92], 'Sec61β': [93], 'Sec61γ': [95], 'showed': [96], 'that': [97, 120, 154, 168, 189, 209, 227], 'these': [98, 155], 'also': [101, 187], 'located': [102], 'ERGIC.': [109], 'Using': [110], 'alternative': [112], 'strategy': [113], 'fractionation,': [116], 'we': [117], 'shown': [119], 'Sec61α,': [122, 128], 'γ,': [125], 'all': [130], 'present': [131, 197], 'ERGIC/Golgi': [138], 'fractions': [139], 'gradient.': [142], 'presence': [144], 'post-ER': [151, 199], 'suggests': [153], 'can': [157], 'escape': [158], 'be': [162], 'recycled': [163], 'back,': [164], 'despite': [165], 'fact': [167], 'none': [169], 'them': [171], 'contain': [172], 'any': [173], 'known': [174], 'membrane': [175], 'protein': [176], 'retrieval': [177, 237], 'signals': [178], 'such': [179], 'as': [180, 201], 'cytosolic': [181], 'di-lysine': [182], 'or': [183], 'di-arginine': [184], 'motifs.': [185], 'another': [190], 'translocon': [191, 217], 'component,': [192], 'glycoprotein': [194], 'TRAM,': [195], 'compartments': [200], 'demonstrated': [202], 'by': [203, 234], 'fractionation.': [205], 'Our': [206], 'data': [207], 'indicate': [208], 'components': [212], 'permanently': [220], 'resident': [221], 'ER,': [224], 'rather': [226], 'they': [228], 'maintained': [230], 'specific': [236], 'mechanism.': [238]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2159336227', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-18T17:07:04.142127', 'created_date': '2016-06-24'}