Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2158315626', 'doi': 'https://doi.org/10.1016/j.bmcl.2004.10.036', 'title': 'Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers', 'display_name': 'Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers', 'publication_year': 2005, 'publication_date': '2005-01-01', 'ids': {'openalex': 'https://openalex.org/W2158315626', 'doi': 'https://doi.org/10.1016/j.bmcl.2004.10.036', 'mag': '2158315626', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15582421'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bmcl.2004.10.036', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30970080', 'display_name': 'Bioorganic & Medicinal Chemistry Letters', 'issn_l': '0960-894X', 'issn': ['0960-894X', '1464-3405'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5053040103', 'display_name': 'Timothy A. Blizzard', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Timothy A. Blizzard', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091681945', 'display_name': 'Frank DiNinno', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Frank DiNinno', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081107625', 'display_name': 'Jerry D Morgan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jerry D. Morgan', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001026535', 'display_name': 'Helen Y. Chen', 'orcid': 'https://orcid.org/0000-0002-1212-943X'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Helen Y. Chen', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008942444', 'display_name': 'Jane Y. Wu', 'orcid': 'https://orcid.org/0000-0003-1794-1213'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jane Y. Wu', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085626805', 'display_name': 'Seongkon Kim', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Seongkon Kim', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041443546', 'display_name': 'Wanda Chan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Wanda Chan', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017198901', 'display_name': 'Elizabeth T. Birzin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Elizabeth T. Birzin', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048242655', 'display_name': 'Yi Yang', 'orcid': 'https://orcid.org/0000-0002-0003-8426'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yi Tien Yang', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064988841', 'display_name': 'Lee-Yuh Pai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lee-Yuh Pai', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008026883', 'display_name': 'Paul J. Fitzgerald', 'orcid': 'https://orcid.org/0000-0002-5216-2189'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paula M.D. Fitzgerald', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072534812', 'display_name': 'Nandini Sharma', 'orcid': 'https://orcid.org/0000-0003-4053-2186'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nandini Sharma', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100414006', 'display_name': 'Ying Li', 'orcid': 'https://orcid.org/0000-0001-5759-8291'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ying Li', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012706313', 'display_name': 'Zhoupeng Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Zhoupeng Zhang', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087658167', 'display_name': 'Edward C. Hayes', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Edward C. Hayes', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045325672', 'display_name': 'Carolyn DaSilva', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Carolyn A. DaSilva', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101624212', 'display_name': 'Wei Tang', 'orcid': 'https://orcid.org/0000-0001-8811-4798'}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Wei Tang', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003433094', 'display_name': 'Susan P. Rohrer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Susan P. Rohrer', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077963933', 'display_name': 'James M. Schaeffer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James M. Schaeffer', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5071129219', 'display_name': 'Milton L. Hammond', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1285764155', 'display_name': 'MSD (United States)', 'ror': 'https://ror.org/02891sr49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1285764155']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Milton L. Hammond', 'raw_affiliation_strings': ['Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA'], 'affiliations': [{'raw_affiliation_string': 'Merck Research Laboratories, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA', 'institution_ids': ['https://openalex.org/I1285764155']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5053040103'], 'corresponding_institution_ids': ['https://openalex.org/I1285764155'], 'apc_list': {'value': 3660, 'currency': 'USD', 'value_usd': 3660, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.382, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 57, 'citation_normalized_percentile': {'value': 0.921214, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '15', 'issue': '1', 'first_page': '107', 'last_page': '113'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10756', 'display_name': 'Mechanisms of Estrogen Receptor Signaling', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10756', 'display_name': 'Mechanisms of Estrogen Receptor Signaling', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T14099', 'display_name': 'Recent Advances in Triazine Chemistry', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T13833', 'display_name': 'Bioorganometallic Chemistry of Ferrocene Derivatives', 'score': 0.9952, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/side-chain', 'display_name': 'Side chain', 'score': 0.8868414}, {'id': 'https://openalex.org/keywords/pyrrolidine', 'display_name': 'Pyrrolidine', 'score': 0.83724725}, {'id': 'https://openalex.org/keywords/linker', 'display_name': 'Linker', 'score': 0.70804363}, {'id': 'https://openalex.org/keywords/estrogen-receptor-modulators', 'display_name': 'Estrogen Receptor Modulators', 'score': 0.516367}], 'concepts': [{'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.92577475}, {'id': 'https://openalex.org/C204921945', 'wikidata': 'https://www.wikidata.org/wiki/Q899689', 'display_name': 'Side chain', 'level': 3, 'score': 0.8868414}, {'id': 'https://openalex.org/C2778851528', 'wikidata': 'https://www.wikidata.org/wiki/Q408898', 'display_name': 'Pyrrolidine', 'level': 2, 'score': 0.83724725}, {'id': 'https://openalex.org/C164361826', 'wikidata': 'https://www.wikidata.org/wiki/Q177604', 'display_name': 'Alkylation', 'level': 3, 'score': 0.7873723}, {'id': 'https://openalex.org/C2780557392', 'wikidata': 'https://www.wikidata.org/wiki/Q523796', 'display_name': 'Linker', 'level': 2, 'score': 0.70804363}, {'id': 'https://openalex.org/C2780263894', 'wikidata': 'https://www.wikidata.org/wiki/Q335268', 'display_name': 'Alkyl', 'level': 2, 'score': 0.67996806}, {'id': 'https://openalex.org/C84606932', 'wikidata': 'https://www.wikidata.org/wiki/Q416496', 'display_name': 'Estrogen receptor', 'level': 4, 'score': 0.5599044}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.46970293}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.4295892}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.28124923}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.20626664}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.09416294}, {'id': 'https://openalex.org/C521977710', 'wikidata': 'https://www.wikidata.org/wiki/Q81163', 'display_name': 'Polymer', 'level': 2, 'score': 0.07089016}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D010075', 'descriptor_name': 'Oxathiins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D011759', 'descriptor_name': 'Pyrrolidines', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011960', 'descriptor_name': 'Receptors, Estrogen', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D020845', 'descriptor_name': 'Selective Estrogen Receptor Modulators', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010075', 'descriptor_name': 'Oxathiins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D010075', 'descriptor_name': 'Oxathiins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011759', 'descriptor_name': 'Pyrrolidines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011960', 'descriptor_name': 'Receptors, Estrogen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011960', 'descriptor_name': 'Receptors, Estrogen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020845', 'descriptor_name': 'Selective Estrogen Receptor Modulators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bmcl.2004.10.036', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30970080', 'display_name': 'Bioorganic & Medicinal Chemistry Letters', 'issn_l': '0960-894X', 'issn': ['0960-894X', '1464-3405'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15582421', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1967004474', 'https://openalex.org/W1969707775', 'https://openalex.org/W2008838316', 'https://openalex.org/W2017030929', 'https://openalex.org/W2028574653', 'https://openalex.org/W2046011994', 'https://openalex.org/W2053259468', 'https://openalex.org/W2055543195', 'https://openalex.org/W2092411075', 'https://openalex.org/W2098010773', 'https://openalex.org/W2101016189', 'https://openalex.org/W2108117526', 'https://openalex.org/W2136139793', 'https://openalex.org/W2148979187', 'https://openalex.org/W2171759718', 'https://openalex.org/W2173110470', 'https://openalex.org/W2177009684', 'https://openalex.org/W2180265416', 'https://openalex.org/W2952501501', 'https://openalex.org/W4237692195'], 'related_works': ['https://openalex.org/W4236406106', 'https://openalex.org/W3174292366', 'https://openalex.org/W2953278966', 'https://openalex.org/W2952344522', 'https://openalex.org/W2949545772', 'https://openalex.org/W2923362377', 'https://openalex.org/W2158315626', 'https://openalex.org/W2086147088', 'https://openalex.org/W2028512683', 'https://openalex.org/W1967275488'], 'abstract_inverted_index': {'A': [0], 'series': [1], 'of': [2], 'dihydrobenzoxathiin': [3], 'SERAMs': [4], 'with': [5], 'alkylated': [6, 11], 'pyrrolidine': [7], 'side': [8, 19], 'chains': [9], 'or': [10, 21], 'linkers': [12], 'was': [13], 'prepared.': [14], 'Minor': [15], 'modifications': [16], 'in': [17, 24, 31], 'the': [18], 'chain': [20], 'linker': [22], 'resulted': [23], 'significant': [25], 'effects': [26], 'on': [27], 'biological': [28], 'activity,': [29], 'especially': [30], 'uterine': [32], 'tissue.': [33]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2158315626', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-09-01T04:23:02.058240', 'created_date': '2016-06-24'}