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'antibiotic': [8, 37, 89, 125, 157, 169, 180, 208, 245], 'treatment': [9, 90, 181], 'for': [10, 31, 200], '7': [11], 'to': [12, 79, 196, 226], '21': [13], 'd.': [14], 'Procalcitonin': [15, 153, 241], 'is': [16], 'elevated': [17], 'in': [18, 39, 212, 217, 231, 247], 'bacterial': [19], 'infections,': [20], 'and': [21, 34, 64, 67, 134, 146, 149, 179, 256], 'its': [22], 'dynamics': [23], 'have': [24, 253], 'prognostic': [25], 'implications.Objective:': [26], 'To': [27], 'assess': [28], 'procalcitonin': [29, 84, 95, 214], 'guidance': [30, 154, 242], 'the': [32, 83, 204, 213, 218], 'initiation': [33], 'duration': [35, 182], 'of': [36, 131, 207, 239], 'therapy': [38], 'pneumonia.Methods:': [41], 'a': [43], 'randomized': [44], 'intervention': [45], 'trial,': [46], '302': [47], 'consecutive': [48], 'suspected': [51], 'pneumonia': [53], 'were': [54, 57, 129, 141], 'included.': [55], 'Data': [56], 'assessed': [58], 'at': [59], 'baseline,': [60, 138], 'after': [61, 68], '4,': [62], '6,': [63], '8': [65], 'd,': [66], '6': [69], 'wk.The': [70], 'control': [71, 219], 'group': [72, 85, 215, 220], '(n': [73, 86], '=': [74, 87], '151)': [75], 'received': [76], 'antibiotics': [77], 'according': [78, 195], 'usual': [80], 'practice.': [81], '151),': [88], 'was': [91, 124, 210, 229], 'based': [92], 'on': [93, 171], 'serum': [94], 'concentrations': [96], 'as': [97], 'follows:': [98], 'strongly': [99, 115], 'discouraged,': [100, 105], 'less': [101, 106], 'than': [102, 107, 112, 118, 216], '0.1': [103], 'μg/L;': [104, 109, 114], '0.25': [108, 113], 'encouraged,': [110, 116], 'greater': [111, 117], '0.5': [119], 'μg/L.': [120], 'The': [121], 'primary': [122], 'endpoint': [123], 'use;': [126], 'secondary': [127], 'endpoints': [128], 'measures': [130], 'clinical,': [132, 144], 'laboratory,': [133, 145], 'radiographic': [135], 'outcome.Results:': [136], 'At': [137], 'both': [139, 232], 'groups': [140], 'similar': [142, 230], 'regarding': [143], 'microbiology': [147], 'characteristics,': [148], 'Pneumonia': [150, 201], 'Severity': [151, 202], 'Index.': [152], 'reduced': [155], 'total': [156], 'exposure': [158], '(relative': [159], 'risk,': [160], '0.52;': [161], '95%': [162, 222], 'confidence': [163, 223], 'interval,': [164, 224], '0.48–0.55;': [165], 'p': [166, 176, 188], '<': [167, 177, 189], '0.001),': [168, 178], 'prescriptions': [170], 'admission': [172], '(85': [173], 'vs.': [174, 185], '99%;': [175], '(median,': [183], '5': [184], '12': [186], 'd;': [187], '0.001)': [190], 'compared': [191], 'treated': [194], 'guidelines.': [197], 'After': [198], 'adjustment': [199], 'Index,': [203], 'hazard': [205], 'ratio': [206], 'discontinuation': [209], 'higher': [211], '(3.2;': [221], '2.5': [225], '4.2).': [227], 'Outcome': [228], 'groups,': [233], 'an': [235], 'overall': [236], 'success': [237], 'rate': [238], '83%.Conclusions:': [240], 'substantially': [243], 'reduces': [244], 'use': [246], 'pneumonia.': [249], 'These': [250], 'findings': [251], 'may': [252], 'important': [254], 'clinical': [255], 'public': [257], 'health': [258], 'implications.': [259]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2158000594', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 24}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 31}, {'year': 2020, 'cited_by_count': 34}, {'year': 2019, 'cited_by_count': 32}, {'year': 2018, 'cited_by_count': 38}, {'year': 2017, 'cited_by_count': 44}, {'year': 2016, 'cited_by_count': 45}, {'year': 2015, 'cited_by_count': 40}, {'year': 2014, 'cited_by_count': 46}, {'year': 2013, 'cited_by_count': 54}, {'year': 2012, 'cited_by_count': 81}], 'updated_date': '2024-09-16T06:11:17.226093', 'created_date': '2016-06-24'}