Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2157335263', 'doi': 'https://doi.org/10.1172/jci69736', 'title': 'Harnessing the potential of epigenetic therapy to target solid tumors', 'display_name': 'Harnessing the potential of epigenetic therapy to target solid tumors', 'publication_year': 2014, 'publication_date': '2014-01-02', 'ids': {'openalex': 'https://openalex.org/W2157335263', 'doi': 'https://doi.org/10.1172/jci69736', 'mag': '2157335263', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24382390', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3871229'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci69736', 'pdf_url': 'http://www.jci.org/articles/view/69736/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.jci.org/articles/view/69736/files/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5090054973', 'display_name': 'Nita Ahuja', 'orcid': 'https://orcid.org/0000-0001-8293-1893'}, 'institutions': [{'id': 'https://openalex.org/I4210164401', 'display_name': 'Sidney Kimmel Comprehensive Cancer Center', 'ror': 'https://ror.org/05m5b8x20', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I2799853436', 'https://openalex.org/I4210164401']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nita Ahuja', 'raw_affiliation_strings': ['The Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'The Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210164401', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034057788', 'display_name': 'Hariharan Easwaran', 'orcid': 'https://orcid.org/0000-0002-5517-2972'}, 'institutions': [{'id': 'https://openalex.org/I4210164401', 'display_name': 'Sidney Kimmel Comprehensive Cancer Center', 'ror': 'https://ror.org/05m5b8x20', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I2799853436', 'https://openalex.org/I4210164401']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hariharan Easwaran', 'raw_affiliation_strings': ['The Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'The Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210164401', 'https://openalex.org/I145311948']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058612163', 'display_name': 'Stephen B. Baylin', 'orcid': 'https://orcid.org/0000-0003-3697-3798'}, 'institutions': [{'id': 'https://openalex.org/I4210164401', 'display_name': 'Sidney Kimmel Comprehensive Cancer Center', 'ror': 'https://ror.org/05m5b8x20', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I2799853436', 'https://openalex.org/I4210164401']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stephen B. Baylin', 'raw_affiliation_strings': ['The Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'The Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210164401', 'https://openalex.org/I145311948']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.962, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 140, 'citation_normalized_percentile': {'value': 0.999748, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '124', 'issue': '1', 'first_page': '56', 'last_page': '63'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetic Modifications and Their Functional Implications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetic Modifications and Their Functional Implications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11736', 'display_name': 'Role of Histone Deacetylases in Cellular Regulation', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12820', 'display_name': 'Chromatin Remodeling in Cancer and Development', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/reprogramming', 'display_name': 'Reprogramming', 'score': 0.7909471}, {'id': 'https://openalex.org/keywords/cancer-epigenetics', 'display_name': 'Cancer Epigenetics', 'score': 0.628157}, {'id': 'https://openalex.org/keywords/epigenetic-therapy', 'display_name': 'Epigenetic Therapy', 'score': 0.619072}, {'id': 'https://openalex.org/keywords/epigenetic-reprogramming', 'display_name': 'Epigenetic Reprogramming', 'score': 0.564927}, {'id': 'https://openalex.org/keywords/epigenetics', 'display_name': 'Epigenetics', 'score': 0.554812}, {'id': 'https://openalex.org/keywords/epigenesis', 'display_name': 'Epigenesis', 'score': 0.5481588}, {'id': 'https://openalex.org/keywords/epigenetic-regulation', 'display_name': 'Epigenetic Regulation', 'score': 0.541332}, {'id': 'https://openalex.org/keywords/cancer-therapy', 'display_name': 'Cancer therapy', 'score': 0.45708513}, {'id': 'https://openalex.org/keywords/epigenomics', 'display_name': 'Epigenomics', 'score': 0.42215517}, {'id': 'https://openalex.org/keywords/targeted-therapy', 'display_name': 'Targeted therapy', 'score': 0.41060305}], 'concepts': [{'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.81537986}, {'id': 'https://openalex.org/C77255625', 'wikidata': 'https://www.wikidata.org/wiki/Q402093', 'display_name': 'Reprogramming', 'level': 3, 'score': 0.7909471}, {'id': 'https://openalex.org/C2780737395', 'wikidata': 'https://www.wikidata.org/wiki/Q18353741', 'display_name': 'Epigenetic therapy', 'level': 5, 'score': 0.7233633}, {'id': 'https://openalex.org/C2779343474', 'wikidata': 'https://www.wikidata.org/wiki/Q3109175', 'display_name': 'Context (archaeology)', 'level': 2, 'score': 0.6385767}, {'id': 'https://openalex.org/C179463898', 'wikidata': 'https://www.wikidata.org/wiki/Q10273301', 'display_name': 'Epigenesis', 'level': 5, 'score': 0.5481588}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.49890256}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.457345}, {'id': 'https://openalex.org/C2983331546', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer therapy', 'level': 3, 'score': 0.45708513}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.4481024}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.44744733}, {'id': 'https://openalex.org/C121912465', 'wikidata': 'https://www.wikidata.org/wiki/Q3589153', 'display_name': 'Epigenomics', 'level': 5, 'score': 0.42215517}, {'id': 'https://openalex.org/C2781230642', 'wikidata': 'https://www.wikidata.org/wiki/Q492646', 'display_name': 'Targeted therapy', 'level': 3, 'score': 0.41060305}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.40721577}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37260553}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.22024417}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13152236}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.11003703}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.06486672}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D044127', 'descriptor_name': 'Epigenesis, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D004248', 'descriptor_name': 'DNA (Cytosine-5-)-Methyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004248', 'descriptor_name': 'DNA (Cytosine-5-)-Methyltransferases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D004248', 'descriptor_name': 'DNA (Cytosine-5-)-Methyltransferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015894', 'descriptor_name': 'Genome, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058990', 'descriptor_name': 'Molecular Targeted Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci69736', 'pdf_url': 'http://www.jci.org/articles/view/69736/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3871229', 'pdf_url': 'https://europepmc.org/articles/pmc3871229?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871229', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24382390', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci69736', 'pdf_url': 'http://www.jci.org/articles/view/69736/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.77}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 127, 'referenced_works': ['https://openalex.org/W1484293540', 'https://openalex.org/W1490231232', 'https://openalex.org/W1504303645', 'https://openalex.org/W1513468396', 'https://openalex.org/W1521333964', 'https://openalex.org/W1528728961', 'https://openalex.org/W1533942477', 'https://openalex.org/W1567517848', 'https://openalex.org/W1619517967', 'https://openalex.org/W1676204041', 'https://openalex.org/W1964767882', 'https://openalex.org/W1964963969', 'https://openalex.org/W1969670934', 'https://openalex.org/W1975141727', 'https://openalex.org/W1975522050', 'https://openalex.org/W1980051146', 'https://openalex.org/W1980937575', 'https://openalex.org/W1983015568', 'https://openalex.org/W1984562049', 'https://openalex.org/W1986586739', 'https://openalex.org/W1987557775', 'https://openalex.org/W1988756388', 'https://openalex.org/W1990381590', 'https://openalex.org/W1995105508', 'https://openalex.org/W1997981312', 'https://openalex.org/W2000156285', 'https://openalex.org/W2001511669', 'https://openalex.org/W2002197756', 'https://openalex.org/W2004380688', 'https://openalex.org/W2007470097', 'https://openalex.org/W2007576179', 'https://openalex.org/W2008051478', 'https://openalex.org/W2008878539', 'https://openalex.org/W2009218955', 'https://openalex.org/W2015085004', 'https://openalex.org/W2017492512', 'https://openalex.org/W2021803200', 'https://openalex.org/W2022240113', 'https://openalex.org/W2025183726', 'https://openalex.org/W2025209702', 'https://openalex.org/W2027591636', 'https://openalex.org/W2027873015', 'https://openalex.org/W2032627213', 'https://openalex.org/W2034352044', 'https://openalex.org/W2034852369', 'https://openalex.org/W2034879676', 'https://openalex.org/W2035393182', 'https://openalex.org/W2036986058', 'https://openalex.org/W2040257851', 'https://openalex.org/W2041396419', 'https://openalex.org/W2041535798', 'https://openalex.org/W2041686632', 'https://openalex.org/W2042087070', 'https://openalex.org/W2044971936', 'https://openalex.org/W2056925335', 'https://openalex.org/W2061946349', 'https://openalex.org/W2063544405', 'https://openalex.org/W2064188460', 'https://openalex.org/W2066818898', 'https://openalex.org/W2074051915', 'https://openalex.org/W2076333986', 'https://openalex.org/W2078972833', 'https://openalex.org/W2081279521', 'https://openalex.org/W2081295565', 'https://openalex.org/W2082477824', 'https://openalex.org/W2082594247', 'https://openalex.org/W2082739830', 'https://openalex.org/W2083960349', 'https://openalex.org/W2089263351', 'https://openalex.org/W2090757807', 'https://openalex.org/W2091685314', 'https://openalex.org/W2092015664', 'https://openalex.org/W2092620739', 'https://openalex.org/W2092761963', 'https://openalex.org/W2094703195', 'https://openalex.org/W2096083625', 'https://openalex.org/W2096283457', 'https://openalex.org/W2099343472', 'https://openalex.org/W2100325414', 'https://openalex.org/W2105100844', 'https://openalex.org/W2106391833', 'https://openalex.org/W2106482095', 'https://openalex.org/W2106584820', 'https://openalex.org/W2107972234', 'https://openalex.org/W2108691088', 'https://openalex.org/W2109710744', 'https://openalex.org/W2113950481', 'https://openalex.org/W2116068882', 'https://openalex.org/W2116739152', 'https://openalex.org/W2117247812', 'https://openalex.org/W2121010151', 'https://openalex.org/W2122953117', 'https://openalex.org/W2123032740', 'https://openalex.org/W2123419812', 'https://openalex.org/W2123731635', 'https://openalex.org/W2124652061', 'https://openalex.org/W2125154191', 'https://openalex.org/W2126665584', 'https://openalex.org/W2126817554', 'https://openalex.org/W2132243740', 'https://openalex.org/W2132310381', 'https://openalex.org/W2134061682', 'https://openalex.org/W2136905998', 'https://openalex.org/W2138809265', 'https://openalex.org/W2139077902', 'https://openalex.org/W2141410747', 'https://openalex.org/W2141476381', 'https://openalex.org/W2142711018', 'https://openalex.org/W2147516356', 'https://openalex.org/W2147944526', 'https://openalex.org/W2148064779', 'https://openalex.org/W2148428508', 'https://openalex.org/W2149426454', 'https://openalex.org/W2150136461', 'https://openalex.org/W2151783390', 'https://openalex.org/W2154313451', 'https://openalex.org/W2156517973', 'https://openalex.org/W2158900087', 'https://openalex.org/W2162093159', 'https://openalex.org/W2167903105', 'https://openalex.org/W2168889003', 'https://openalex.org/W2169903102', 'https://openalex.org/W2170210082', 'https://openalex.org/W2171365282', 'https://openalex.org/W2262414037', 'https://openalex.org/W2275877493', 'https://openalex.org/W2328946792'], 'related_works': ['https://openalex.org/W4389786764', 'https://openalex.org/W4229335609', 'https://openalex.org/W3095323983', 'https://openalex.org/W2540215816', 'https://openalex.org/W2507652170', 'https://openalex.org/W2064121515', 'https://openalex.org/W2046783559', 'https://openalex.org/W2043014869', 'https://openalex.org/W2034557579', 'https://openalex.org/W2010174303'], 'abstract_inverted_index': {'Epigenetic': [0], 'therapies': [1, 123], 'may': [2, 52], 'play': [3], 'a': [4, 54, 63], 'prominent': [5], 'role': [6], 'in': [7, 25, 44, 69, 74, 91, 101, 106], 'the': [8, 19, 72, 77, 92, 119], 'future': [9, 120], 'management': [10], 'of': [11, 22, 80, 94, 103, 113, 121], 'solid': [12, 45, 60], 'tumors.': [13, 46], 'This': [14], 'possibility': [15], 'is': [16], 'based': [17], 'on': [18], 'clinical': [20, 38], 'efficacy': [21], 'existing': [23], 'drugs': [24, 51, 115], 'treating': [26], 'defined': [27], 'hematopoietic': [28], 'neoplasms,': [29], 'paired': [30], 'with': [31, 71, 108], 'promising': [32], 'new': [33, 114], 'data': [34], 'from': [35], 'preclinical': [36], 'and': [37, 82, 97, 100], 'studies': [39], 'that': [40, 49, 65, 87, 110], 'examined': [41], 'these': [42], 'agents': [43], 'We': [47, 85], 'suggest': [48], 'current': [50], 'represent': [53], 'targeted': [55, 89], 'therapeutic': [56], 'approach': [57], 'for': [58, 124], 'reprogramming': [59], 'tumor': [61], 'cells,': [62], 'strategy': [64], 'must': [66], 'be': [67], 'pursued': [68], 'concert': [70], 'explosion': [73], 'knowledge': [75], 'about': [76], 'molecular': [78], 'underpinnings': [79], 'normal': [81], 'cancer': [83], 'epigenomes.': [84], 'hypothesize': [86], 'understanding': [88], 'proteins': [90, 109], 'context': [93], 'their': [95, 104], 'enzymatic': [96], 'scaffolding': [98], 'functions': [99], 'terms': [102], 'interactions': [105], 'complexes': [107], 'are': [111], 'targets': [112], 'under': [116], 'development': [117], 'defines': [118], 'epigenetic': [122], 'cancer.': [125]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2157335263', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 22}, {'year': 2016, 'cited_by_count': 24}, {'year': 2015, 'cited_by_count': 21}, {'year': 2014, 'cited_by_count': 9}], 'updated_date': '2024-09-16T07:10:30.906249', 'created_date': '2016-06-24'}