Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2157274804', 'doi': 'https://doi.org/10.1002/ana.410430406', 'title': 'Valproate, lamotrigine, and insulin‐mediated risks in women with epilepsy', 'display_name': 'Valproate, lamotrigine, and insulin‐mediated risks in women with epilepsy', 'publication_year': 1998, 'publication_date': '1998-04-01', 'ids': {'openalex': 'https://openalex.org/W2157274804', 'doi': 'https://doi.org/10.1002/ana.410430406', 'mag': '2157274804', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9546324'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/ana.410430406', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114530997', 'display_name': 'Annals of Neurology', 'issn_l': '0364-5134', 'issn': ['0364-5134', '1531-8249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5060176494', 'display_name': 'Jouko Isojärvi', 'orcid': 'https://orcid.org/0000-0002-1620-0280'}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': True, 'raw_author_name': 'Jouko I. T. Isojärvi', 'raw_affiliation_strings': ['Department of Neurology, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017684078', 'display_name': 'Johanna Rättyä', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Johanna Rättyä', 'raw_affiliation_strings': ['Department of Neurology, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005022085', 'display_name': 'Vilho V. Myllylä', 'orcid': 'https://orcid.org/0000-0003-3736-7095'}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Vilho V. Myllylä', 'raw_affiliation_strings': ['Department of Neurology, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000141478', 'display_name': 'Mikael Knip', 'orcid': 'https://orcid.org/0000-0003-0474-0033'}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Mikael Knip', 'raw_affiliation_strings': ['Department of Pediatrics, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056891937', 'display_name': 'Riitta Koivunen', 'orcid': 'https://orcid.org/0000-0002-4257-9335'}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Riitta Koivunen', 'raw_affiliation_strings': ['Department of Obstetrics and Gynecology, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynecology, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013863914', 'display_name': 'A. Pakarinen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799272722', 'display_name': 'Oulu University Hospital', 'ror': 'https://ror.org/045ney286', 'country_code': 'FI', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799272722']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Arto J. Pakarinen', 'raw_affiliation_strings': ['Laboratory of Oulu University Hospital, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Oulu University Hospital, Oulu, Finland', 'institution_ids': ['https://openalex.org/I2799272722']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039077529', 'display_name': 'Aydin Tekay', 'orcid': 'https://orcid.org/0000-0002-4746-8837'}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Aydin Tekay', 'raw_affiliation_strings': ['Department of Obstetrics and Gynecology, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynecology, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009732804', 'display_name': 'Juha S. Tapanainen', 'orcid': 'https://orcid.org/0000-0002-3139-9128'}, 'institutions': [{'id': 'https://openalex.org/I98381234', 'display_name': 'University of Oulu', 'ror': 'https://ror.org/03yj89h83', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I98381234']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Juha S. Tapanainen', 'raw_affiliation_strings': ['Department of Obstetrics and Gynecology, University of Oulu, Oulu, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynecology, University of Oulu, Oulu, Finland', 'institution_ids': ['https://openalex.org/I98381234']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5060176494'], 'corresponding_institution_ids': ['https://openalex.org/I98381234'], 'apc_list': {'value': 3610, 'currency': 'USD', 'value_usd': 3610, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 25.061, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 338, 'citation_normalized_percentile': {'value': 0.98433, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '43', 'issue': '4', 'first_page': '446', 'last_page': '451'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12229', 'display_name': 'Prenatal Exposure to Antiepileptic Drugs', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12229', 'display_name': 'Prenatal Exposure to Antiepileptic Drugs', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10554', 'display_name': 'Genetic and Clinical Aspects of Hemoglobin Disorders', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10094', 'display_name': 'Epilepsy and Seizures', 'score': 0.9923, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hyperandrogenism', 'display_name': 'Hyperandrogenism', 'score': 0.8689368}, {'id': 'https://openalex.org/keywords/hyperinsulinemia', 'display_name': 'Hyperinsulinemia', 'score': 0.86038476}, {'id': 'https://openalex.org/keywords/maternal-epilepsy', 'display_name': 'Maternal Epilepsy', 'score': 0.474927}], 'concepts': [{'id': 'https://openalex.org/C2780186808', 'wikidata': 'https://www.wikidata.org/wiki/Q10529545', 'display_name': 'Hyperandrogenism', 'level': 5, 'score': 0.8689368}, {'id': 'https://openalex.org/C2780988686', 'wikidata': 'https://www.wikidata.org/wiki/Q14375936', 'display_name': 'Hyperinsulinemia', 'level': 4, 'score': 0.86038476}, {'id': 'https://openalex.org/C2778802184', 'wikidata': 'https://www.wikidata.org/wiki/Q410346', 'display_name': 'Lamotrigine', 'level': 3, 'score': 0.82525635}, {'id': 'https://openalex.org/C3018442814', 'wikidata': 'https://www.wikidata.org/wiki/Q500816', 'display_name': 'Polycystic ovary', 'level': 4, 'score': 0.7114734}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6905116}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6673869}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.65024066}, {'id': 'https://openalex.org/C2778186239', 'wikidata': 'https://www.wikidata.org/wiki/Q41571', 'display_name': 'Epilepsy', 'level': 2, 'score': 0.64460886}, {'id': 'https://openalex.org/C2780221984', 'wikidata': 'https://www.wikidata.org/wiki/Q131191', 'display_name': 'Body mass index', 'level': 2, 'score': 0.46608752}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.30898666}, {'id': 'https://openalex.org/C2777391703', 'wikidata': 'https://www.wikidata.org/wiki/Q1053470', 'display_name': 'Insulin resistance', 'level': 3, 'score': 0.24362367}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.09362456}], 'mesh': [{'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D004827', 'descriptor_name': 'Epilepsy', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D017588', 'descriptor_name': 'Hyperandrogenism', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D006946', 'descriptor_name': 'Hyperinsulinism', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D010053', 'descriptor_name': 'Ovary', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D011085', 'descriptor_name': 'Polycystic Ovary Syndrome', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D014227', 'descriptor_name': 'Triazines', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D014635', 'descriptor_name': 'Valproic Acid', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000704', 'descriptor_name': 'Analysis of Variance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D008076', 'descriptor_name': 'Cholesterol, HDL', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008076', 'descriptor_name': 'Cholesterol, HDL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004827', 'descriptor_name': 'Epilepsy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004827', 'descriptor_name': 'Epilepsy', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017588', 'descriptor_name': 'Hyperandrogenism', 'qualifier_ui': 'Q000000981', 'qualifier_name': 'diagnostic imaging', 'is_major_topic': False}, {'descriptor_ui': 'D017588', 'descriptor_name': 'Hyperandrogenism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006946', 'descriptor_name': 'Hyperinsulinism', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D006946', 'descriptor_name': 'Hyperinsulinism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077213', 'descriptor_name': 'Lamotrigine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008597', 'descriptor_name': 'Menstrual Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010053', 'descriptor_name': 'Ovary', 'qualifier_ui': 'Q000000981', 'qualifier_name': 'diagnostic imaging', 'is_major_topic': False}, {'descriptor_ui': 'D010053', 'descriptor_name': 'Ovary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011085', 'descriptor_name': 'Polycystic Ovary Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011085', 'descriptor_name': 'Polycystic Ovary Syndrome', 'qualifier_ui': 'Q000000981', 'qualifier_name': 'diagnostic imaging', 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014227', 'descriptor_name': 'Triazines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D014227', 'descriptor_name': 'Triazines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014463', 'descriptor_name': 'Ultrasonography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014635', 'descriptor_name': 'Valproic Acid', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D014635', 'descriptor_name': 'Valproic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/ana.410430406', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114530997', 'display_name': 'Annals of Neurology', 'issn_l': '0364-5134', 'issn': ['0364-5134', '1531-8249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9546324', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.8, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1969062482', 'https://openalex.org/W1973962145', 'https://openalex.org/W1984513597', 'https://openalex.org/W1988297715', 'https://openalex.org/W2003517642', 'https://openalex.org/W2015605491', 'https://openalex.org/W2029582373', 'https://openalex.org/W2039674635', 'https://openalex.org/W2048606830', 'https://openalex.org/W2079769181', 'https://openalex.org/W2092413298', 'https://openalex.org/W2094881693', 'https://openalex.org/W2096773810', 'https://openalex.org/W2120557435', 'https://openalex.org/W2150121392', 'https://openalex.org/W2161305604', 'https://openalex.org/W2163597003', 'https://openalex.org/W2170407184', 'https://openalex.org/W2318408074', 'https://openalex.org/W2322086287', 'https://openalex.org/W2338906118', 'https://openalex.org/W2341665659', 'https://openalex.org/W2416940695', 'https://openalex.org/W4248786607', 'https://openalex.org/W4251533758', 'https://openalex.org/W4319308421'], 'related_works': ['https://openalex.org/W3199496467', 'https://openalex.org/W2955334283', 'https://openalex.org/W2564128998', 'https://openalex.org/W2434689181', 'https://openalex.org/W2365997838', 'https://openalex.org/W2130343438', 'https://openalex.org/W2074654627', 'https://openalex.org/W2036554817', 'https://openalex.org/W2000231342', 'https://openalex.org/W1555836579'], 'abstract_inverted_index': {'We': [0], 'recently': [1], 'reported': [2], 'the': [3, 31, 42, 54, 74, 92, 123, 132], 'frequent': [4], 'occurrence': [5], 'of': [6, 25, 148], 'polycystic': [7, 48, 149, 181], 'ovaries': [8, 49, 150], 'and': [9, 15, 37, 60, 62, 73, 106, 114, 118, 180], 'hyperandrogenism': [10, 51], 'associated': [11, 104], 'with': [12, 46, 103, 129, 167, 174, 185], 'weight': [13], 'gain': [14], 'hyperinsulinemia': [16, 36, 105], 'in': [17, 53, 151, 183], 'women': [18, 45, 84, 90, 153, 184], 'taking': [19], 'valproate': [20, 72, 98, 128, 158, 166], 'for': [21, 71, 78, 196], 'epilepsy.': [22, 186], 'The': [23, 111, 145], 'purpose': [24], 'this': [26], 'study': [27], 'was': [28, 58, 69], 'to': [29, 34, 141, 160], 'evaluate': [30], 'risks': [32, 189], 'related': [33], 'valproate-induced': [35], 'their': [38], 'reversibility': [39], 'after': [40, 126, 164], 'discontinuing': [41], 'medication.': [43], 'Sixteen': [44], 'valproate-related': [47, 188], 'or': [50], 'participated': [52], 'study.': [55], 'Vaginal': [56], 'ultrasonography': [57], 'performed,': [59], 'endocrine': [61], 'lipid': [63, 109, 178], 'parameters': [64], 'were': [65, 76], 'measured.': [66], 'Thereafter,': [67], 'lamotrigine': [68, 130, 195], 'substituted': [70], 'patients': [75], 'observed': [77], '12': [79], 'months.': [80], 'Twenty-four': [81], 'healthy': [82], 'age-matched': [83], 'served': [85], 'as': [86], 'control': [87], 'subjects.': [88], 'Twelve': [89], 'completed': [91], '12-month': [93], 'follow-up.': [94], 'While': [95], 'still': [96], 'on': [97], 'they': [99], 'had': [100], 'centripetal': [101, 175], 'obesity': [102], 'unfavorable': [107], 'serum': [108, 116], 'profiles.': [110], 'body-mass': [112], 'index': [113], 'fasting': [115], 'insulin': [117], 'testosterone': [119], 'concentrations': [120], 'decreased': [121, 154], 'during': [122, 157], 'first': [124], 'year': [125, 163], 'replacing': [127, 165], 'whereas': [131], 'HDL-cholesterol/total': [133], 'cholesterol': [134], 'ratios': [135], 'increased': [136], 'from': [137, 155], '0.17': [138], '+/-': [139, 143], '0.06': [140], '0.26': [142], '0.05.': [144], 'total': [146], 'number': [147], 'these': [152], '20': [156], 'medication': [159], '11': [161], 'one': [162], 'lamotrigine.': [168], 'Valproate': [169], 'induces': [170], 'a': [171], 'metabolic': [172], 'syndrome': [173], 'obesity,': [176], 'hyperinsulinemia,': [177], 'abnormalities,': [179], 'ovaries/hyperandrogenism': [182], 'These': [187], 'can': [190], 'be': [191], 'reduced': [192], 'by': [193], 'substituting': [194], 'valproate.': [197]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2157274804', 'counts_by_year': [{'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 13}], 'updated_date': '2024-09-01T04:21:03.566386', 'created_date': '2016-06-24'}