Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2157018093', 'doi': 'https://doi.org/10.1093/nass/nrm107', 'title': 'Repair mechanism of DNA-protein cross-link damage in Escherichia coli', 'display_name': 'Repair mechanism of DNA-protein cross-link damage in Escherichia coli', 'publication_year': 2007, 'publication_date': '2007-11-01', 'ids': {'openalex': 'https://openalex.org/W2157018093', 'doi': 'https://doi.org/10.1093/nass/nrm107', 'mag': '2157018093', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18029662'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nass/nrm107', 'pdf_url': 'https://academic.oup.com/nass/article-pdf/51/1/213/3379077/nrm107.pdf', 'source': {'id': 'https://openalex.org/S193378857', 'display_name': 'Nucleic Acids Symposium Series', 'issn_l': '0261-3166', 'issn': ['0261-3166', '1746-8272'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/nass/article-pdf/51/1/213/3379077/nrm107.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5106892411', 'display_name': 'Toshiaki Nakano', 'orcid': 'https://orcid.org/0000-0002-5274-2909'}, 'institutions': [{'id': 'https://openalex.org/I113306721', 'display_name': 'Hiroshima University', 'ror': 'https://ror.org/03t78wx29', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I113306721']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'T. Nakano', 'raw_affiliation_strings': ['Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and'], 'affiliations': [{'raw_affiliation_string': 'Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and', 'institution_ids': ['https://openalex.org/I113306721']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053518592', 'display_name': 'Shoji Morishita', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I113306721', 'display_name': 'Hiroshima University', 'ror': 'https://ror.org/03t78wx29', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I113306721']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'S. Morishita', 'raw_affiliation_strings': ['Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and'], 'affiliations': [{'raw_affiliation_string': 'Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and', 'institution_ids': ['https://openalex.org/I113306721']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017284430', 'display_name': 'Hiroaki Terato', 'orcid': 'https://orcid.org/0000-0002-7070-5263'}, 'institutions': [{'id': 'https://openalex.org/I113306721', 'display_name': 'Hiroshima University', 'ror': 'https://ror.org/03t78wx29', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I113306721']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'H. Terato', 'raw_affiliation_strings': ['Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and'], 'affiliations': [{'raw_affiliation_string': 'Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and', 'institution_ids': ['https://openalex.org/I113306721']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087977112', 'display_name': 'Seung Pil Pack', 'orcid': 'https://orcid.org/0000-0002-4874-0265'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'S. P. Pack', 'raw_affiliation_strings': ['Institute of Advanced Energy, Kyoto University, Gokasho, Uji 611-0011,Japan'], 'affiliations': [{'raw_affiliation_string': 'Institute of Advanced Energy, Kyoto University, Gokasho, Uji 611-0011,Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083588840', 'display_name': 'Keisuke Makino', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'K. Makino', 'raw_affiliation_strings': ['Institute of Advanced Energy, Kyoto University, Gokasho, Uji 611-0011,Japan'], 'affiliations': [{'raw_affiliation_string': 'Institute of Advanced Energy, Kyoto University, Gokasho, Uji 611-0011,Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5062807755', 'display_name': 'Ide H', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I113306721', 'display_name': 'Hiroshima University', 'ror': 'https://ror.org/03t78wx29', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I113306721']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'H. Ide', 'raw_affiliation_strings': ['Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and'], 'affiliations': [{'raw_affiliation_string': 'Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan and', 'institution_ids': ['https://openalex.org/I113306721']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.506846, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 74, 'max': 76}, 'biblio': {'volume': '51', 'issue': '1', 'first_page': '213', 'last_page': '214'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10878', 'display_name': 'Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins', 'score': 0.9879, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10303', 'display_name': 'Molecular Mechanisms of Photosynthesis and Photoprotection', 'score': 0.9371, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dna-damage', 'display_name': 'DNA Damage', 'score': 0.601072}, {'id': 'https://openalex.org/keywords/cross-link', 'display_name': 'Cross-link', 'score': 0.4570598}], 'concepts': [{'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.8519759}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.70872295}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.7068418}, {'id': 'https://openalex.org/C134935766', 'wikidata': 'https://www.wikidata.org/wiki/Q210538', 'display_name': 'DNA repair', 'level': 3, 'score': 0.6959032}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.51255107}, {'id': 'https://openalex.org/C142708767', 'wikidata': 'https://www.wikidata.org/wiki/Q898597', 'display_name': 'Cross-link', 'level': 3, 'score': 0.4570598}, {'id': 'https://openalex.org/C18231593', 'wikidata': 'https://www.wikidata.org/wiki/Q186161', 'display_name': 'Ionizing radiation', 'level': 3, 'score': 0.41253638}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.40866756}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.38317642}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.37281758}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.36139733}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.19356787}, {'id': 'https://openalex.org/C111337013', 'wikidata': 'https://www.wikidata.org/wiki/Q2737837', 'display_name': 'Irradiation', 'level': 2, 'score': 0.117829144}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C185544564', 'wikidata': 'https://www.wikidata.org/wiki/Q81197', 'display_name': 'Nuclear physics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C521977710', 'wikidata': 'https://www.wikidata.org/wiki/Q81163', 'display_name': 'Polymer', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018736', 'descriptor_name': 'DNA Adducts', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D045643', 'descriptor_name': 'DNA Repair Enzymes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011684', 'descriptor_name': 'Purine Nucleosides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D003432', 'descriptor_name': 'Cross-Linking Reagents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003432', 'descriptor_name': 'Cross-Linking Reagents', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D018736', 'descriptor_name': 'DNA Adducts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018736', 'descriptor_name': 'DNA Adducts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D045647', 'descriptor_name': 'DNA Glycosylases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045647', 'descriptor_name': 'DNA Glycosylases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D045643', 'descriptor_name': 'DNA Repair Enzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005557', 'descriptor_name': 'Formaldehyde', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005557', 'descriptor_name': 'Formaldehyde', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011684', 'descriptor_name': 'Purine Nucleosides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nass/nrm107', 'pdf_url': 'https://academic.oup.com/nass/article-pdf/51/1/213/3379077/nrm107.pdf', 'source': {'id': 'https://openalex.org/S193378857', 'display_name': 'Nucleic Acids Symposium Series', 'issn_l': '0261-3166', 'issn': ['0261-3166', '1746-8272'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18029662', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nass/nrm107', 'pdf_url': 'https://academic.oup.com/nass/article-pdf/51/1/213/3379077/nrm107.pdf', 'source': {'id': 'https://openalex.org/S193378857', 'display_name': 'Nucleic Acids Symposium Series', 'issn_l': '0261-3166', 'issn': ['0261-3166', '1746-8272'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3125757075', 'https://openalex.org/W2760815521', 'https://openalex.org/W2747101336', 'https://openalex.org/W2108718931', 'https://openalex.org/W2107516157', 'https://openalex.org/W2055890925', 'https://openalex.org/W2033918102', 'https://openalex.org/W2004480716', 'https://openalex.org/W1991644354', 'https://openalex.org/W1972094156'], 'abstract_inverted_index': {'DNA-protein': [0], 'cross-link': [1], '(DPC)': [2], 'damage': [3], 'is': [4], 'produced': [5], 'by': [6], 'varieties': [7], 'of': [8, 74], 'genotoxic': [9], 'agents': [10], 'such': [11], 'as': [12], 'ionizing': [13], 'radiation,': [14], 'UV': [15], 'light,': [16], 'aldehydes,': [17], 'and': [18, 63], 'some': [19], 'chemotherapeutic': [20], 'compounds.': [21], 'DPCs': [22, 47, 62], 'would': [23], 'be': [24], 'harmful': [25], 'to': [26, 77], 'cells': [27], 'since': [28], 'proteins': [29], 'immobilized': [30], 'on': [31], 'DNA': [32, 36, 58], 'strands': [33], 'could': [34], 'hamper': [35], 'transactions': [37], 'in': [38, 50], 'cells.': [39, 51], 'However,': [40], 'it': [41], 'has': [42], 'not': [43], 'been': [44], 'clarified': [45], 'how': [46], 'are': [48], 'repaired': [49], 'In': [52], 'the': [53, 72], 'present': [54], 'study,': [55], 'we': [56], 'prepared': [57], 'substrates': [59], 'containing': [60], 'defined': [61], 'tested': [64], 'them': [65], 'for': [66], 'repair': [67], 'enzymes.': [68], 'We': [69], 'also': [70], 'examined': [71], 'sensitivity': [73], 'Escherichia': [75], 'coli': [76], 'DPC-inducing': [78], 'agents.': [79]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2157018093', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-16T06:34:10.242956', 'created_date': '2016-06-24'}