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'secreted': [6], 'preferentially': [7], 'by': [8, 140, 166], 'cortical': [9], 'γ-aminobutyric': [10], 'acid-ergic': [11], '(GABAergic)': [12], 'interneurons': [13, 33], '(layers': [14], 'I': [15], 'and': [16, 59, 73, 104, 115, 120, 149, 156, 158, 204, 212, 232, 240], 'II)': [17], 'that': [18, 49, 57, 202, 251, 270, 278], 'binds': [19], 'to': [20, 74, 168, 208, 216], 'integrin': [21], 'receptors': [22], 'located': [23], 'on': [24, 31], 'dendritic': [25], 'spines': [26], 'of': [27, 34, 90, 97, 152, 223, 230, 236, 263], 'pyramidal': [28], 'neurons': [29, 137], 'or': [30, 132, 174, 221], 'GABAergic': [32], 'layers': [35], 'III': [36], 'through': [37], 'V': [38], 'expressing': [39], 'the': [40, 249, 261, 264, 276], 'disabled-1': [41], 'gene': [42], 'product': [43], '(DAB1),': [44], 'cytosolic': [46], 'adaptor': [47], 'protein': [48], 'mediates': [50], 'RELN': [51, 58, 153, 203, 231], 'action.': [52], 'To': [53], 'replicate': [54], 'earlier': [55], 'findings': [56], 'glutamic': [60], 'acid': [61], 'decarboxylase': [62], '(GAD)<sub>67</sub>,': [63], 'but': [64, 179], 'not': [65, 180], 'DAB1': [66], 'expression,': [67], 'are': [68, 254], 'down-regulated': [69], 'in': [70, 170, 181, 257, 272], 'schizophrenic': [71], 'brains,': [72, 93], 'verify': [75], 'whether': [76], 'other': [77], 'psychiatric': [78], 'disorders': [79], 'express': [80], 'similar': [81], 'deficits,': [82], 'we': [83], 'analyzed,': [84], 'blind,': [85], 'an': [86], 'entirely': [87], 'new': [88], 'cohort': [89], '60': [91], 'postmortem': [92, 217], 'including': [94], 'equal': [95], 'numbers': [96], 'patients': [98, 171, 237], 'matched': [99], 'for': [100, 197], 'schizophrenia,': [101], 'unipolar': [102, 184], 'depression,': [103], 'bipolar': [105, 175, 241], 'disorder': [106, 176, 242], 'with': [107, 125, 172, 177, 183, 190, 238, 248], 'nonpsychiatric': [108, 191], 'subjects.': [109, 192], '<h3>Methods</h3>': [110], 'Reelin,': [111], 'GAD<sub>65</sub>,': [112], 'GAD<sub>67</sub>,': [113], 'DAB1,': [114], 'neuron-specific–enolase': [116, 199], 'messenger': [117], 'RNAs': [118], '(mRNAs)': [119], 'respective': [121], 'proteins': [122], 'were': [123, 138, 195, 206], 'measured': [124], 'quantitative': [126], 'reverse': [127], 'transcriptase–polymerase': [128], 'chain': [129], 'reaction': [130], '(RT-PCR)': [131], 'Western': [133], 'blot': [134], 'analyses.': [135], 'Reelin-positive': [136], 'identified': [139], 'immunohistochemistry': [141], 'using': [142], 'monoclonal': [144], 'antibody.': [145], '<h3>Results</h3>': [146], 'Prefrontal': [147], 'cortex': [148, 160, 235], 'cerebellar': [150], 'expression': [151, 200], 'mRNA,': [154, 157], 'GAD<sub>67</sub>protein': [155], 'prefrontal': [159, 234], 'RELN-positive': [161], 'cells': [162], 'was': [163], 'significantly': [164], 'decreased': [165], '30%': [167], '50%': [169], 'schizophrenia': [173, 239], 'psychosis,': [178], 'those': [182], 'depression': [185], 'without': [186], 'psychosis': [187, 245], 'when': [188], 'compared': [189], 'Group': [193], 'differences': [194], 'absent': [196], 'DAB1,GAD<sub>65</sub>and': [198], 'implying': [201], 'GAD<sub>67</sub>down-regulations': [205], 'unrelated': [207, 215], 'neuronal': [209], 'damage.': [210], 'GAD<sub>67</sub>were': [213], 'also': [214], 'intervals,': [218], 'dose,': [219], 'duration,': [220], 'presence': [222], 'antipsychotic': [224], 'medication.': [225], '<h3>Conclusions</h3>': [226], 'The': [227], 'selective': [228], 'down-regulation': [229], 'GAD<sub>67</sub>in': [233], 'who': [243], 'have': [244], 'consistent': [247], 'hypothesis': [250, 277], 'these': [252, 267, 279], 'parameters': [253, 269], 'vulnerability': [255], 'factors': [256, 284], 'psychosis;': [258], 'this': [259], 'plus': [260], 'loss': [262], 'correlation': [265], 'between': [266], '2': [268], 'exists': [271], 'nonpsychotic': [273], 'subjects': [274], 'support': [275], 'changes': [280], 'may': [281], 'be': [282], 'liability': [283], 'underlying': [285], 'psychosis.': [286]}, 'cited_by_api_url': 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