Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2156017880', 'doi': 'https://doi.org/10.1099/0022-1317-68-5-1457', 'title': 'Human Monoclonal Antibodies Neutralizing Human Cytomegalovirus', 'display_name': 'Human Monoclonal Antibodies Neutralizing Human Cytomegalovirus', 'publication_year': 1987, 'publication_date': '1987-05-01', 'ids': {'openalex': 'https://openalex.org/W2156017880', 'doi': 'https://doi.org/10.1099/0022-1317-68-5-1457', 'mag': '2156017880', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2437245'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1099/0022-1317-68-5-1457', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S103035011', 'display_name': 'Journal of General Virology', 'issn_l': '0022-1317', 'issn': ['0022-1317', '1465-2099'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320497', 'host_organization_name': 'Microbiology Society', 'host_organization_lineage': ['https://openalex.org/P4310320497'], 'host_organization_lineage_names': ['Microbiology Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1099/0022-1317-68-5-1457', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111600306', 'display_name': 'Yasuhiko Masuho', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90469020', 'display_name': 'Teijin (Japan)', 'ror': 'https://ror.org/038kxkq33', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I90469020']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Y. Masuho', 'raw_affiliation_strings': ['Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191'], 'affiliations': [{'raw_affiliation_string': 'Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191', 'institution_ids': ['https://openalex.org/I90469020']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037797581', 'display_name': 'Yoh‐ichi Matsumoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90469020', 'display_name': 'Teijin (Japan)', 'ror': 'https://ror.org/038kxkq33', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I90469020']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Y.-I. Matsumoto', 'raw_affiliation_strings': ['Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191'], 'affiliations': [{'raw_affiliation_string': 'Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191', 'institution_ids': ['https://openalex.org/I90469020']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111667603', 'display_name': 'T Sugano', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90469020', 'display_name': 'Teijin (Japan)', 'ror': 'https://ror.org/038kxkq33', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I90469020']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'T. Sugano', 'raw_affiliation_strings': ['Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191'], 'affiliations': [{'raw_affiliation_string': 'Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191', 'institution_ids': ['https://openalex.org/I90469020']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113544701', 'display_name': 'S. Fujinaga', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90469020', 'display_name': 'Teijin (Japan)', 'ror': 'https://ror.org/038kxkq33', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I90469020']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'S. Fujinaga', 'raw_affiliation_strings': ['Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191'], 'affiliations': [{'raw_affiliation_string': 'Teijin Institute for Biomedical Research, Asahigaoka, 4-3-2, Hino-city, Tokyo 191', 'institution_ids': ['https://openalex.org/I90469020']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5089040335', 'display_name': 'Yoichi Minamishima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210135803', 'display_name': 'Miyazaki Welfare Medical College', 'ror': 'https://ror.org/03jrtp196', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210135803']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Y. Minamishima', 'raw_affiliation_strings': ['Department of Microbiology, Miyazaki Medical College, Miyazaki, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Miyazaki Medical College, Miyazaki, Japan', 'institution_ids': ['https://openalex.org/I4210135803']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.344, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.891552, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '68', 'issue': '5', 'first_page': '1457', 'last_page': '1461'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10625', 'display_name': 'Herpesvirus Infections and Treatments', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/infectivity', 'display_name': 'Infectivity', 'score': 0.6397607}, {'id': 'https://openalex.org/keywords/cytomegalovirus', 'display_name': 'Cytomegalovirus', 'score': 0.5850986}, {'id': 'https://openalex.org/keywords/cell-fusion', 'display_name': 'Cell fusion', 'score': 0.45337224}], 'concepts': [{'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.87562954}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.8561048}, {'id': 'https://openalex.org/C2779820661', 'wikidata': 'https://www.wikidata.org/wiki/Q6929', 'display_name': 'Human cytomegalovirus', 'level': 3, 'score': 0.7292195}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6913952}, {'id': 'https://openalex.org/C106358424', 'wikidata': 'https://www.wikidata.org/wiki/Q1662346', 'display_name': 'Infectivity', 'level': 3, 'score': 0.6397607}, {'id': 'https://openalex.org/C14086860', 'wikidata': 'https://www.wikidata.org/wiki/Q337120', 'display_name': 'Neutralization', 'level': 3, 'score': 0.6064511}, {'id': 'https://openalex.org/C2777732132', 'wikidata': 'https://www.wikidata.org/wiki/Q6946', 'display_name': 'Cytomegalovirus', 'level': 5, 'score': 0.5850986}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.55300933}, {'id': 'https://openalex.org/C92488253', 'wikidata': 'https://www.wikidata.org/wiki/Q56592403', 'display_name': 'Cell fusion', 'level': 3, 'score': 0.45337224}, {'id': 'https://openalex.org/C2780931953', 'wikidata': 'https://www.wikidata.org/wiki/Q9371', 'display_name': 'Spleen', 'level': 2, 'score': 0.44649473}, {'id': 'https://openalex.org/C2779261636', 'wikidata': 'https://www.wikidata.org/wiki/Q7003054', 'display_name': 'Neutralizing antibody', 'level': 3, 'score': 0.43190098}, {'id': 'https://openalex.org/C195616568', 'wikidata': 'https://www.wikidata.org/wiki/Q128711', 'display_name': 'Epitope', 'level': 3, 'score': 0.42816174}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.29294482}, {'id': 'https://openalex.org/C2776409557', 'wikidata': 'https://www.wikidata.org/wiki/Q149348', 'display_name': 'Herpesviridae', 'level': 4, 'score': 0.28082436}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.26406246}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.23568222}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.1358242}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000914', 'descriptor_name': 'Antibodies, Viral', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D003587', 'descriptor_name': 'Cytomegalovirus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000914', 'descriptor_name': 'Antibodies, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D003587', 'descriptor_name': 'Cytomegalovirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009500', 'descriptor_name': 'Neutralization Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1099/0022-1317-68-5-1457', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S103035011', 'display_name': 'Journal of General Virology', 'issn_l': '0022-1317', 'issn': ['0022-1317', '1465-2099'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320497', 'host_organization_name': 'Microbiology Society', 'host_organization_lineage': ['https://openalex.org/P4310320497'], 'host_organization_lineage_names': ['Microbiology Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2437245', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1099/0022-1317-68-5-1457', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S103035011', 'display_name': 'Journal of General Virology', 'issn_l': '0022-1317', 'issn': ['0022-1317', '1465-2099'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320497', 'host_organization_name': 'Microbiology Society', 'host_organization_lineage': ['https://openalex.org/P4310320497'], 'host_organization_lineage_names': ['Microbiology Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.62, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 13, 'referenced_works': ['https://openalex.org/W1512083200', 'https://openalex.org/W1579549231', 'https://openalex.org/W1867720626', 'https://openalex.org/W1971005837', 'https://openalex.org/W1997885157', 'https://openalex.org/W2002184199', 'https://openalex.org/W2017790686', 'https://openalex.org/W2043917207', 'https://openalex.org/W2093697123', 'https://openalex.org/W2100837269', 'https://openalex.org/W2169367665', 'https://openalex.org/W2329179876', 'https://openalex.org/W983515058'], 'related_works': ['https://openalex.org/W2766580945', 'https://openalex.org/W2156017880', 'https://openalex.org/W2128900924', 'https://openalex.org/W2101049085', 'https://openalex.org/W2087994121', 'https://openalex.org/W2037922132', 'https://openalex.org/W2022468004', 'https://openalex.org/W1990581446', 'https://openalex.org/W1976482169', 'https://openalex.org/W1975565982'], 'abstract_inverted_index': {'Hybridomas': [0], 'producing': [1], 'human': [2, 7, 15, 75], 'monoclonal': [3], 'antibodies': [4], '(MAbs)': [5], 'against': [6, 85], 'cytomegalovirus': [8], '(CMV)': [9], 'were': [10], 'generated': [11], 'by': [12], 'fusion': [13], 'of': [14, 23, 54, 68, 82], 'spleen': [16], 'cells': [17], 'and': [18, 57], 'mouse': [19], 'myeloma': [20], 'cells.': [21, 70], 'Two': [22], 'the': [24, 45, 65], 'six': [25], 'MAbs': [26, 50, 62, 76], 'obtained': [27], 'neutralized': [28], 'viral': [29, 52], 'infectivity': [30], 'even': [31], 'at': [32], 'concentrations': [33], 'lower': [34], 'than': [35], '1': [36], 'microgram/ml.': [37], 'One': [38], 'MAb': [39], 'required': [40], 'complement': [41], 'for': [42], 'neutralization': [43], 'but': [44], 'other': [46], 'did': [47], 'not.': [48], 'Both': [49], 'recognized': [51], 'proteins': [53], 'Mr': [55], '130,000': [56], '55,000.': [58], 'Furthermore,': [59], 'these': [60], 'neutralizing': [61], 'bound': [63], 'to': [64], 'surface': [66], 'membrane': [67], 'CMV-infected': [69], 'These': [71], 'results': [72], 'suggest': [73], 'that': [74], 'may': [77], 'provide': [78], 'a': [79], 'new': [80], 'means': [81], 'passive': [83], 'immunization': [84], 'CMV': [86], 'infection': [87], 'in': [88], 'humans.': [89]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2156017880', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-12-13T14:10:03.822846', 'created_date': '2016-06-24'}