Title: Confirmatory Seamless Phase II/III Clinical Trials with Hypotheses Selection at Interim: Opportunities and Limitations
Abstract: This is a discussion of the following two papers in this special issue on adaptive designs: 'Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: General concepts' by Frank Bretz, Heinz Schmidli, Franz König, Amy Racine and Willi Maurer, and 'Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: Applications and practical considerations' by Heinz Schmidli, Frank Bretz, Amy Racine and Willi Maurer.
Publication Year: 2006
Publication Date: 2006-08-01
Language: en
Type: letter
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 44
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