Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2155650069', 'doi': 'https://doi.org/10.1007/s00705-008-0110-1', 'title': 'Effect of siRNA on HSV-1 plaque formation and relative expression levels of UL39 mRNA', 'display_name': 'Effect of siRNA on HSV-1 plaque formation and relative expression levels of UL39 mRNA', 'publication_year': 2008, 'publication_date': '2008-06-13', 'ids': {'openalex': 'https://openalex.org/W2155650069', 'doi': 'https://doi.org/10.1007/s00705-008-0110-1', 'mag': '2155650069', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18551244'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00705-008-0110-1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S57491091', 'display_name': 'Archives of Virology', 'issn_l': '0304-8608', 'issn': ['0304-8608', '1432-8798'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084078237', 'display_name': 'Zhe Ren', 'orcid': 'https://orcid.org/0000-0001-7573-5288'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ren Zhe', 'raw_affiliation_strings': ['College of Life Sciences of Sichuan University, Chengdu, Sichuan, 610000, China'], 'affiliations': [{'raw_affiliation_string': 'College of Life Sciences of Sichuan University, Chengdu, Sichuan, 610000, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033267594', 'display_name': 'Meiying Zhang', 'orcid': 'https://orcid.org/0000-0002-1785-573X'}, 'institutions': [{'id': 'https://openalex.org/I159948400', 'display_name': 'Jinan University', 'ror': 'https://ror.org/02xe5ns62', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I159948400']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhang Mei-Ying', 'raw_affiliation_strings': ['Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510000, China'], 'affiliations': [{'raw_affiliation_string': 'Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510000, China', 'institution_ids': ['https://openalex.org/I159948400']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066962081', 'display_name': 'Kaio Kitazato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kaio Kitazato', 'raw_affiliation_strings': ['Laboratory of Molecular Biology of Infectious Agents, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Molecular Biology of Infectious Agents, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012893337', 'display_name': 'Nobuyuki Kobayash', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Nobuyuki Kobayash', 'raw_affiliation_strings': ['Laboratory of Molecular Biology of Infectious Agents, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Molecular Biology of Infectious Agents, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100519581', 'display_name': 'Qinchang Zhu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159948400', 'display_name': 'Jinan University', 'ror': 'https://ror.org/02xe5ns62', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I159948400']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhu Qin-Chang', 'raw_affiliation_strings': ['Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510000, China'], 'affiliations': [{'raw_affiliation_string': 'Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510000, China', 'institution_ids': ['https://openalex.org/I159948400']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016460712', 'display_name': 'Pei‐Zhuo Zhang', 'orcid': 'https://orcid.org/0000-0002-4137-9489'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhang Pei-Zhuo', 'raw_affiliation_strings': ['Shanghai GenePharma Co., Ltd, Shanghai, 201203, China'], 'affiliations': [{'raw_affiliation_string': 'Shanghai GenePharma Co., Ltd, Shanghai, 201203, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100297294', 'display_name': 'Zhirong Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159948400', 'display_name': 'Jinan University', 'ror': 'https://ror.org/02xe5ns62', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I159948400']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yang Zhi-Rong', 'raw_affiliation_strings': ['Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510630, China'], 'affiliations': [{'raw_affiliation_string': 'Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510630, China', 'institution_ids': ['https://openalex.org/I159948400']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103664701', 'display_name': 'Wang Yi-fei', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159948400', 'display_name': 'Jinan University', 'ror': 'https://ror.org/02xe5ns62', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I159948400']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wang Yi-Fei', 'raw_affiliation_strings': ['Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510000, China'], 'affiliations': [{'raw_affiliation_string': 'Biomedicine Research and Development Center of Jinan University, Guangzhou, Guangdong, 510000, China', 'institution_ids': ['https://openalex.org/I159948400']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.645, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.84657, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '153', 'issue': '7', 'first_page': '1401', 'last_page': '1406'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10625', 'display_name': 'Herpesviruses: Epidemiology, Pathogenesis, and Management', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10625', 'display_name': 'Herpesviruses: Epidemiology, Pathogenesis, and Management', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10613', 'display_name': 'Gene Therapy Techniques and Applications', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10725', 'display_name': 'Mechanisms and Applications of RNA Interference', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ribonucleotide-reductase', 'display_name': 'Ribonucleotide reductase', 'score': 0.78027093}, {'id': 'https://openalex.org/keywords/rna-interference', 'display_name': 'RNA Interference', 'score': 0.593517}, {'id': 'https://openalex.org/keywords/therapeutic-rnai', 'display_name': 'Therapeutic RNAi', 'score': 0.525462}, {'id': 'https://openalex.org/keywords/sirna-therapeutics', 'display_name': 'siRNA Therapeutics', 'score': 0.522686}, {'id': 'https://openalex.org/keywords/trans-acting-sirna', 'display_name': 'Trans-acting siRNA', 'score': 0.49707487}, {'id': 'https://openalex.org/keywords/rna-silencing', 'display_name': 'RNA silencing', 'score': 0.48343906}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8399863}, {'id': 'https://openalex.org/C166703698', 'wikidata': 'https://www.wikidata.org/wiki/Q201993', 'display_name': 'RNA interference', 'level': 4, 'score': 0.8050045}, {'id': 'https://openalex.org/C4710235', 'wikidata': 'https://www.wikidata.org/wiki/Q420089', 'display_name': 'Ribonucleotide reductase', 'level': 4, 'score': 0.78027093}, {'id': 'https://openalex.org/C22615655', 'wikidata': 'https://www.wikidata.org/wiki/Q203221', 'display_name': 'Small interfering RNA', 'level': 4, 'score': 0.751701}, {'id': 'https://openalex.org/C2781196997', 'wikidata': 'https://www.wikidata.org/wiki/Q655331', 'display_name': 'Herpes simplex virus', 'level': 3, 'score': 0.64901423}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.54701674}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.53340626}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.498796}, {'id': 'https://openalex.org/C60723119', 'wikidata': 'https://www.wikidata.org/wiki/Q7833577', 'display_name': 'Trans-acting siRNA', 'level': 5, 'score': 0.49707487}, {'id': 'https://openalex.org/C2191507', 'wikidata': 'https://www.wikidata.org/wiki/Q7277185', 'display_name': 'RNA silencing', 'level': 5, 'score': 0.48343906}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.4817262}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.473997}, {'id': 'https://openalex.org/C54009773', 'wikidata': 'https://www.wikidata.org/wiki/Q1429031', 'display_name': 'Transfection', 'level': 3, 'score': 0.4215037}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.41618037}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.3278467}, {'id': 'https://openalex.org/C104292427', 'wikidata': 'https://www.wikidata.org/wiki/Q899781', 'display_name': 'Protein subunit', 'level': 3, 'score': 0.2765081}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13622943}], 'mesh': [{'descriptor_ui': 'D018259', 'descriptor_name': 'Herpesvirus 1, Human', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D034741', 'descriptor_name': 'RNA, Small Interfering', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D010948', 'descriptor_name': 'Viral Plaque Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002522', 'descriptor_name': 'Chlorocebus aethiops', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020868', 'descriptor_name': 'Gene Silencing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018259', 'descriptor_name': 'Herpesvirus 1, Human', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018259', 'descriptor_name': 'Herpesvirus 1, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034741', 'descriptor_name': 'RNA, Small Interfering', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014709', 'descriptor_name': 'Vero Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00705-008-0110-1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S57491091', 'display_name': 'Archives of Virology', 'issn_l': '0304-8608', 'issn': ['0304-8608', '1432-8798'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18551244', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.42}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1664735557', 'https://openalex.org/W1684170753', 'https://openalex.org/W1947168737', 'https://openalex.org/W1967248009', 'https://openalex.org/W1974303227', 'https://openalex.org/W1978155015', 'https://openalex.org/W1992501118', 'https://openalex.org/W1995768712', 'https://openalex.org/W1996498777', 'https://openalex.org/W2006902703', 'https://openalex.org/W2008631953', 'https://openalex.org/W2024825275', 'https://openalex.org/W2036776952', 'https://openalex.org/W2041024249', 'https://openalex.org/W2049265285', 'https://openalex.org/W2056650797', 'https://openalex.org/W2058247709', 'https://openalex.org/W2071596792', 'https://openalex.org/W2078949471', 'https://openalex.org/W2087846171', 'https://openalex.org/W2107277218', 'https://openalex.org/W2112349562', 'https://openalex.org/W2117648777', 'https://openalex.org/W2123365280', 'https://openalex.org/W2124694752', 'https://openalex.org/W2128212057', 'https://openalex.org/W2149316882', 'https://openalex.org/W2167414261', 'https://openalex.org/W2178778111', 'https://openalex.org/W2351256540', 'https://openalex.org/W2361709420'], 'related_works': ['https://openalex.org/W2783595154', 'https://openalex.org/W2392176201', 'https://openalex.org/W2373307833', 'https://openalex.org/W2167018286', 'https://openalex.org/W2160381063', 'https://openalex.org/W2074731420', 'https://openalex.org/W2044279756', 'https://openalex.org/W2039740951', 'https://openalex.org/W1968291875', 'https://openalex.org/W1930224804'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2155650069', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-08-15T13:28:21.834168', 'created_date': '2016-06-24'}