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'secondary': [37, 68, 158, 187], 'binding': [38, 74], 'site,': [39], 'were': [40, 133], 'characterized': [41], 'order': [43], 'to': [44, 52, 84, 164], 'understand': [45], 'why': [46], 'disruption': [47], 'this': [49], 'site': [50, 75, 160, 189], 'leads': [51], 'enhanced': [53, 81, 117], 'filament': [54], 'disassembly.': [55], 'Crystal': [56], 'structures': [57], 'showed': [61], 'mutations': [64], 'specifically': [65], 'affect': [66], 'actin‐binding': [69, 159, 188], 'interface,': [70], 'leaving': [71], 'primary': [73], 'unaltered.': [76], 'The': [77], 'mutant': [78, 143], 'cofilins': [79, 144], 'show': [80], 'activity': [82], 'compared': [83], 'wild‐type': [85, 106, 131], 'cofilin': [86, 175], 'severing': [88, 138], 'disassembling': [90], 'filaments.': [92, 169], 'Electron': [93], 'microscopy': [94, 121], 'image': [96], 'analysis': [97], 'revealed': [98], 'long': [99], 'while': [108], 'induced': [111], 'many': [112], 'short': [113], 'filaments,': [114], 'consistent': [115], 'with': [116], 'severing.': [118], 'Real‐time': [119], 'fluorescence': [120], 'labeled': [123], 'confirmed': [126], 'mutants,': [129], 'unlike': [130], 'functioning': [134], 'as': [135], 'constitutively': [136], 'active': [137], 'proteins.': [139], 'In': [140], 'cells,': [141], 'delayed': [145], 'endocytosis,': [146], 'which': [147], 'depends': [148], 'rapid': [150], 'turnover.': [152], 'We': [153, 170], 'conclude': [154], 'mutating': [156], 'increases': [161], 'ability': [163], 'sever': [165], 'de‐polymerize': [167], 'hypothesize': [171], 'activators': [173], 'severing,': [176], 'like': [177], 'Aip1p,': [178], 'may': [179], 'act': [180], 'by': [181], 'disrupting': [182], 'interface': [184], 'between': [185], 'filament.': [193], '©': [194], '2014': [195], 'Wiley': [196], 'Periodicals,': [197], 'Inc.': [198]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2154617002', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 3}], 'updated_date': '2024-08-15T13:27:02.797970', 'created_date': '2016-06-24'}