Publication Information

{'id': 'https://openalex.org/W2154156472', 'doi': 'https://doi.org/10.7326/0003-4819-143-8-200510180-00007', 'title': 'Effect of a Second-Generation Venous Catheter Impregnated with Chlorhexidine and Silver Sulfadiazine on Central Catheter–Related Infections', 'display_name': 'Effect of a Second-Generation Venous Catheter Impregnated with Chlorhexidine and Silver Sulfadiazine on Central Catheter–Related Infections', 'publication_year': 2005, 'publication_date': '2005-10-18', 'ids': {'openalex': 'https://openalex.org/W2154156472', 'doi': 'https://doi.org/10.7326/0003-4819-143-8-200510180-00007', 'mag': '2154156472', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16230723'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/0003-4819-143-8-200510180-00007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5009557285', 'display_name': 'Mark E. Rupp', 'orcid': 'https://orcid.org/0000-0001-8946-8272'}, 'institutions': [{'id': 'https://openalex.org/I59130452', 'display_name': 'University of Nebraska Medical Center', 'ror': 'https://ror.org/00thqtb16', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I59130452']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Mark E. Rupp', 'raw_affiliation_strings': ['University of Nebraska Medical Center, Omaha, Nebraska, USA. [email protected]'], 'affiliations': [{'raw_affiliation_string': 'University of Nebraska Medical Center, Omaha, Nebraska, USA. [email protected]', 'institution_ids': ['https://openalex.org/I59130452']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5009557285'], 'corresponding_institution_ids': ['https://openalex.org/I59130452'], 'apc_list': None, 'apc_paid': None, 'fwci': 23.644, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 231, 'citation_normalized_percentile': {'value': 0.979632, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '143', 'issue': '8', 'first_page': '570', 'last_page': '570'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10641', 'display_name': 'Central Venous Catheters and Hemodialysis', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/3604', 'display_name': 'Emergency Medical Services'}, 'field': {'id': 'https://openalex.org/fields/36', 'display_name': 'Health Professions'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10641', 'display_name': 'Central Venous Catheters and Hemodialysis', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/3604', 'display_name': 'Emergency Medical Services'}, 'field': {'id': 'https://openalex.org/fields/36', 'display_name': 'Health Professions'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11153', 'display_name': 'Streptococcal Infections and Treatments', 'score': 0.9749, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11000', 'display_name': 'Infection Control in Healthcare', 'score': 0.9718, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/antiseptic', 'display_name': 'Antiseptic', 'score': 0.74270535}, {'id': 'https://openalex.org/keywords/silver-sulfadiazine', 'display_name': 'Silver sulfadiazine', 'score': 0.6354942}, {'id': 'https://openalex.org/keywords/central-venous-catheter', 'display_name': 'Central venous catheter', 'score': 0.5238804}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.90085936}, {'id': 'https://openalex.org/C2781267111', 'wikidata': 'https://www.wikidata.org/wiki/Q652297', 'display_name': 'Catheter', 'level': 2, 'score': 0.7655697}, {'id': 'https://openalex.org/C2781460226', 'wikidata': 'https://www.wikidata.org/wiki/Q274493', 'display_name': 'Antiseptic', 'level': 2, 'score': 0.74270535}, {'id': 'https://openalex.org/C2776532303', 'wikidata': 'https://www.wikidata.org/wiki/Q420984', 'display_name': 'Silver sulfadiazine', 'level': 3, 'score': 0.6354942}, {'id': 'https://openalex.org/C2777084678', 'wikidata': 'https://www.wikidata.org/wiki/Q15646788', 'display_name': 'Chlorhexidine', 'level': 2, 'score': 0.6118556}, {'id': 'https://openalex.org/C2778446481', 'wikidata': 'https://www.wikidata.org/wiki/Q190404', 'display_name': 'Central venous catheter', 'level': 3, 'score': 0.5238804}, {'id': 'https://openalex.org/C166888038', 'wikidata': 'https://www.wikidata.org/wiki/Q4118322', 'display_name': 'Infection control', 'level': 2, 'score': 0.48408973}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.48314828}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34997892}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.3331277}, {'id': 'https://openalex.org/C2780269544', 'wikidata': 'https://www.wikidata.org/wiki/Q1509074', 'display_name': 'Wound healing', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C199343813', 'wikidata': 'https://www.wikidata.org/wiki/Q12128', 'display_name': 'Dentistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000891', 'descriptor_name': 'Anti-Infective Agents, Local', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D016470', 'descriptor_name': 'Bacteremia', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D002405', 'descriptor_name': 'Catheterization, Central Venous', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': True}, {'descriptor_ui': 'D002408', 'descriptor_name': 'Catheters, Indwelling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002710', 'descriptor_name': 'Chlorhexidine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D012837', 'descriptor_name': 'Silver Sulfadiazine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000891', 'descriptor_name': 'Anti-Infective Agents, Local', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016470', 'descriptor_name': 'Bacteremia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002405', 'descriptor_name': 'Catheterization, Central Venous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002710', 'descriptor_name': 'Chlorhexidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004866', 'descriptor_name': 'Equipment Contamination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012837', 'descriptor_name': 'Silver Sulfadiazine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/0003-4819-143-8-200510180-00007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16230723', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.67, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 25, 'referenced_works': ['https://openalex.org/W1949131150', 'https://openalex.org/W1965191517', 'https://openalex.org/W1992651335', 'https://openalex.org/W2010074829', 'https://openalex.org/W2013128224', 'https://openalex.org/W2017319091', 'https://openalex.org/W2022056467', 'https://openalex.org/W2025288141', 'https://openalex.org/W2028812334', 'https://openalex.org/W2037918377', 'https://openalex.org/W2071109466', 'https://openalex.org/W2105157052', 'https://openalex.org/W2127048943', 'https://openalex.org/W2128173445', 'https://openalex.org/W2161182983', 'https://openalex.org/W2168664318', 'https://openalex.org/W2169113006', 'https://openalex.org/W2314608485', 'https://openalex.org/W2315332680', 'https://openalex.org/W2325546012', 'https://openalex.org/W2398868417', 'https://openalex.org/W2413051274', 'https://openalex.org/W2616153379', 'https://openalex.org/W2616251258', 'https://openalex.org/W2781474784'], 'related_works': ['https://openalex.org/W3153916057', 'https://openalex.org/W2802429509', 'https://openalex.org/W2526846910', 'https://openalex.org/W2473004373', 'https://openalex.org/W2429033381', 'https://openalex.org/W2344261407', 'https://openalex.org/W2189175684', 'https://openalex.org/W2033547664', 'https://openalex.org/W2010070306', 'https://openalex.org/W106414831'], 'abstract_inverted_index': {'Background:': [0], 'Central': [1], 'venous': [2, 75], 'catheter–related': [3], 'infections': [4], 'are': [5, 13], 'a': [6, 21, 81, 85], 'significant': [7], 'medical': [8, 63], 'problem.': [9], 'Improved': [10], 'preventive': [11], 'measures': [12], 'needed.': [14], 'Objective:': [15], 'To': [16], 'ascertain': [17], '1)': [18], 'effectiveness': [19], 'of': [20, 28, 37, 42, 51, 115, 126, 152, 194, 306], 'second-generation': [22, 292], 'antiseptic-coated': [23], 'catheter': [24, 83, 86, 97, 117, 230, 270, 295, 308], 'in': [25, 68, 254], 'the': [26, 49, 116, 123, 150, 212, 228, 242, 307], 'prevention': [27], 'microbial': [29, 304], 'colonization': [30, 98, 176, 305], 'and': [31, 35, 45, 90, 99, 107, 136, 181, 237, 278], 'infection;': [32], '2)': [33], 'safety': [34], 'tolerability': [36], 'this': [38], 'device;': [39], '3)': [40], 'microbiology': [41], 'infected': [43], 'catheters;': [44], '4)': [46], 'propensity': [47], 'for': [48, 139, 175, 178, 211, 227, 261], 'development': [50], 'antiseptic': [52, 229, 269], 'resistance.': [53], 'Design:': [54], 'Multicenter,': [55], 'randomized,': [56], 'double-blind,': [57], 'controlled': [58], 'trial.': [59], 'Setting:': [60], '9': [61], 'university-affiliated': [62], 'centers.': [64], 'Patients:': [65], '780': [66], 'patients': [67], 'intensive': [69], 'care': [70], 'units': [71], 'who': [72], 'required': [73], 'central': [74], 'catheterization.': [76], 'Intervention:': [77], 'Patients': [78, 121], 'received': [79], 'either': [80, 265], 'standard': [82], 'or': [84], 'coated': [87], 'with': [88, 122, 155, 274, 310], 'chlorhexidine': [89], 'silver': [91], 'sulfadiazine.': [92], 'Measurements:': [93], 'The': [94, 169, 192, 268, 291], 'authors': [95], 'assessed': [96], 'catheter-related': [100, 196], 'infection,': [101], 'characterized': [102], 'microbes': [103, 245, 262], 'by': [104], 'molecular': [105], 'typing,': [106], 'determined': [108], 'their': [109], 'susceptibility': [110, 258], 'to': [111, 146, 190, 206, 222, 246, 302], 'antiseptics.': [112], 'Patient': [113], 'tolerance': [114], 'was': [118, 185, 199, 259, 271], 'monitored.': [119], 'Results:': [120], '2': [124], 'types': [125], 'catheters': [127, 142, 157, 162], 'had': [128], 'similar': [129, 253, 260], 'demographic': [130], 'features,': [131], 'clinical': [132], 'interventions,': [133], 'laboratory': [134], 'values,': [135], 'risk': [137], 'factors': [138], 'infection.': [140, 289], 'Antiseptic': [141, 257, 299], 'were': [143, 241, 252], 'less': [144], 'likely': [145], 'be': [147, 282], 'colonized': [148, 161], 'at': [149], 'time': [151], 'removal': [153], 'compared': [154, 273, 309], 'control': [156, 213], '(13.3': [158], 'vs.': [159], '24.1': [160], 'per': [163, 201, 208, 217, 224], '1000': [164, 202, 209, 218, 225], 'catheter-days;': [165], 'P': [166], '<': [167], '0.01).': [168], 'center-stratified': [170], 'Cox': [171], 'regression': [172], 'hazard': [173], 'ratio': [174], 'controlling': [177], 'sampling': [179], 'design': [180], 'potentially': [182], 'confounding': [183], 'variables': [184], '0.45': [186], '(95%': [187], 'CI,': [188], '0.25': [189], '0.78).': [191], 'rate': [193], 'definitive': [195], 'bloodstream': [197, 288], 'infection': [198], '1.24': [200], 'catheter-days': [203, 219], '(CI,': [204, 220], '0.26': [205], '3.62': [207], 'catheter-days)': [210, 226], 'group': [214, 231], 'versus': [215], '0.42': [216], '0.01': [221], '2.34': [223], '(P': [232], '=': [233], '0.6).': [234], 'Coagulase-negative': [235], 'staphylococci': [236], 'other': [238], 'gram-positive': [239], 'organisms': [240], 'most': [243], 'frequent': [244], 'colonize': [247], 'catheters.': [248], 'Noninfectious': [249], 'adverse': [250], 'events': [251], 'both': [255], 'groups.': [256], 'recovered': [263], 'from': [264], 'group.': [266], 'Limitations:': [267], 'not': [272], 'an': [275, 311], 'antibiotic-coated': [276], 'catheter,': [277], 'no': [279], 'conclusion': [280], 'can': [281], 'made': [283], 'regarding': [284], 'its': [285], 'effect': [286], 'on': [287], 'Conclusions:': [290], 'chlorhexidine–silver': [293], 'sulfadiazine': [294], 'is': [296], 'well': [297], 'tolerated.': [298], 'coating': [300], 'appears': [301], 'reduce': [303], 'uncoated': [312], 'catheter.': [313]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2154156472', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 16}, {'year': 2016, 'cited_by_count': 15}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 20}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 18}], 'updated_date': '2024-12-14T05:59:17.124452', 'created_date': '2016-06-24'}