Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2154041910', 'doi': 'https://doi.org/10.1083/jcb.200303158', 'title': 'Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation', 'display_name': 'Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation', 'publication_year': 2003, 'publication_date': '2003-09-01', 'ids': {'openalex': 'https://openalex.org/W2154041910', 'doi': 'https://doi.org/10.1083/jcb.200303158', 'mag': '2154041910', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12952940', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2172823'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.200303158', 'pdf_url': 'https://rupress.org/jcb/article-pdf/162/5/899/1310052/jcb1625899.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://rupress.org/jcb/article-pdf/162/5/899/1310052/jcb1625899.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5046244490', 'display_name': 'Lilia Topol', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090236', 'display_name': 'National Human Genome Research Institute', 'ror': 'https://ror.org/00baak391', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210090236']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lilia Topol', 'raw_affiliation_strings': ['Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892'], 'affiliations': [{'raw_affiliation_string': 'Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892', 'institution_ids': ['https://openalex.org/I4210090236', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103571856', 'display_name': 'Xueyuan Jiang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090236', 'display_name': 'National Human Genome Research Institute', 'ror': 'https://ror.org/00baak391', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210090236']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Xueyuan Jiang', 'raw_affiliation_strings': ['Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892'], 'affiliations': [{'raw_affiliation_string': 'Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892', 'institution_ids': ['https://openalex.org/I4210090236', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5104098077', 'display_name': 'Hosoon Choi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090236', 'display_name': 'National Human Genome Research Institute', 'ror': 'https://ror.org/00baak391', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210090236']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hosoon Choi', 'raw_affiliation_strings': ['Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892'], 'affiliations': [{'raw_affiliation_string': 'Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892', 'institution_ids': ['https://openalex.org/I4210090236', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069944202', 'display_name': 'Lisa Garrett‐Beal', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090236', 'display_name': 'National Human Genome Research Institute', 'ror': 'https://ror.org/00baak391', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210090236']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lisa Garrett-Beal', 'raw_affiliation_strings': ['Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892'], 'affiliations': [{'raw_affiliation_string': 'Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892', 'institution_ids': ['https://openalex.org/I4210090236', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009116940', 'display_name': 'Peter J. Carolan', 'orcid': 'https://orcid.org/0000-0003-4386-0310'}, 'institutions': [{'id': 'https://openalex.org/I4210090236', 'display_name': 'National Human Genome Research Institute', 'ror': 'https://ror.org/00baak391', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210090236']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Peter J. Carolan', 'raw_affiliation_strings': ['Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892'], 'affiliations': [{'raw_affiliation_string': 'Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892', 'institution_ids': ['https://openalex.org/I4210090236', 'https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5016326637', 'display_name': 'Yingzi Yang', 'orcid': 'https://orcid.org/0000-0003-3933-887X'}, 'institutions': [{'id': 'https://openalex.org/I4210090236', 'display_name': 'National Human Genome Research Institute', 'ror': 'https://ror.org/00baak391', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210090236']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yingzi Yang', 'raw_affiliation_strings': ['Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892'], 'affiliations': [{'raw_affiliation_string': 'Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892', 'institution_ids': ['https://openalex.org/I4210090236', 'https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 12.591, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 716, 'citation_normalized_percentile': {'value': 0.999978, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '162', 'issue': '5', 'first_page': '899', 'last_page': '908'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9744, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/beta-catenin', 'display_name': 'Beta-catenin', 'score': 0.79212606}, {'id': 'https://openalex.org/keywords/lrp5', 'display_name': 'LRP5', 'score': 0.7323928}, {'id': 'https://openalex.org/keywords/lrp6', 'display_name': 'LRP6', 'score': 0.72063255}, {'id': 'https://openalex.org/keywords/wnt3a', 'display_name': 'WNT3A', 'score': 0.4614474}], 'concepts': [{'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.9673372}, {'id': 'https://openalex.org/C2779324961', 'wikidata': 'https://www.wikidata.org/wiki/Q1634046', 'display_name': 'Beta-catenin', 'level': 4, 'score': 0.79212606}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7852671}, {'id': 'https://openalex.org/C182819311', 'wikidata': 'https://www.wikidata.org/wiki/Q18028670', 'display_name': 'LRP5', 'level': 4, 'score': 0.7323928}, {'id': 'https://openalex.org/C170320316', 'wikidata': 'https://www.wikidata.org/wiki/Q18028667', 'display_name': 'LRP6', 'level': 4, 'score': 0.72063255}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.66867596}, {'id': 'https://openalex.org/C30145163', 'wikidata': 'https://www.wikidata.org/wiki/Q384104', 'display_name': 'Catenin', 'level': 4, 'score': 0.63080484}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.4622521}, {'id': 'https://openalex.org/C2779131293', 'wikidata': 'https://www.wikidata.org/wiki/Q18048098', 'display_name': 'WNT3A', 'level': 4, 'score': 0.4614474}], 'mesh': [{'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D038362', 'descriptor_name': 'Glycogen Synthase Kinase 3', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D025601', 'descriptor_name': 'Adenomatous Polyposis Coli Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025601', 'descriptor_name': 'Adenomatous Polyposis Coli Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054732', 'descriptor_name': 'Calcium-Calmodulin-Dependent Protein Kinase Type 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017871', 'descriptor_name': 'Calcium-Calmodulin-Dependent Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017871', 'descriptor_name': 'Calcium-Calmodulin-Dependent Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046508', 'descriptor_name': 'Culture Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004622', 'descriptor_name': 'Embryo, Mammalian', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D004622', 'descriptor_name': 'Embryo, Mammalian', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004622', 'descriptor_name': 'Embryo, Mammalian', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004628', 'descriptor_name': 'Embryonic Structures', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004628', 'descriptor_name': 'Embryonic Structures', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017930', 'descriptor_name': 'Genes, Reporter', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D038362', 'descriptor_name': 'Glycogen Synthase Kinase 3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050778', 'descriptor_name': 'NFATC Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071818', 'descriptor_name': 'Wnt-5a Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.200303158', 'pdf_url': 'https://rupress.org/jcb/article-pdf/162/5/899/1310052/jcb1625899.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2172823', 'pdf_url': 'https://europepmc.org/articles/pmc2172823?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172823', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12952940', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.200303158', 'pdf_url': 'https://rupress.org/jcb/article-pdf/162/5/899/1310052/jcb1625899.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1485377536', 'https://openalex.org/W1489145497', 'https://openalex.org/W1494249446', 'https://openalex.org/W1500827124', 'https://openalex.org/W1504655784', 'https://openalex.org/W1521657513', 'https://openalex.org/W1554815317', 'https://openalex.org/W1569503463', 'https://openalex.org/W1572014524', 'https://openalex.org/W1611720630', 'https://openalex.org/W1664587663', 'https://openalex.org/W1974921930', 'https://openalex.org/W1978047924', 'https://openalex.org/W1982266611', 'https://openalex.org/W1984273067', 'https://openalex.org/W1989361508', 'https://openalex.org/W1997829008', 'https://openalex.org/W2000352591', 'https://openalex.org/W2005096820', 'https://openalex.org/W2020484263', 'https://openalex.org/W2020634703', 'https://openalex.org/W2023002592', 'https://openalex.org/W2027932074', 'https://openalex.org/W2030556604', 'https://openalex.org/W2037128138', 'https://openalex.org/W2039285533', 'https://openalex.org/W2046386430', 'https://openalex.org/W2048471338', 'https://openalex.org/W2051788298', 'https://openalex.org/W2060089472', 'https://openalex.org/W2064537289', 'https://openalex.org/W2075726466', 'https://openalex.org/W2078016003', 'https://openalex.org/W2083573833', 'https://openalex.org/W2087393103', 'https://openalex.org/W2090851532', 'https://openalex.org/W2091605975', 'https://openalex.org/W2098067206', 'https://openalex.org/W2100070586', 'https://openalex.org/W2101713299', 'https://openalex.org/W2102512718', 'https://openalex.org/W2105565758', 'https://openalex.org/W2107106369', 'https://openalex.org/W2111334408', 'https://openalex.org/W2114163924', 'https://openalex.org/W2131151657', 'https://openalex.org/W2140328069', 'https://openalex.org/W2141108067', 'https://openalex.org/W2144212847', 'https://openalex.org/W2146167376', 'https://openalex.org/W2147257521', 'https://openalex.org/W2150589615', 'https://openalex.org/W2155348369', 'https://openalex.org/W2159831275', 'https://openalex.org/W2161073961', 'https://openalex.org/W2164964874', 'https://openalex.org/W2165061154', 'https://openalex.org/W2166254889', 'https://openalex.org/W2185588425', 'https://openalex.org/W2274730818', 'https://openalex.org/W4213241491'], 'related_works': ['https://openalex.org/W2768101470', 'https://openalex.org/W2143353042', 'https://openalex.org/W2107825767', 'https://openalex.org/W2087124418', 'https://openalex.org/W2078040721', 'https://openalex.org/W2054774672', 'https://openalex.org/W1993933453', 'https://openalex.org/W1982773061', 'https://openalex.org/W1974997800', 'https://openalex.org/W1965766281'], 'abstract_inverted_index': {'Wnts': [0], 'are': [1], 'secreted': [2], 'signaling': [3], 'molecules': [4], 'that': [5, 69], 'can': [6], 'transduce': [7], 'their': [8], 'signals': [9], 'through': [10, 39], 'several': [11], 'different': [12], 'pathways.': [13], 'Wnt-5a': [14, 41, 70], 'is': [15, 55], 'considered': [16], 'a': [17, 35], 'noncanonical': [18, 37], 'Wnt': [19, 45], 'as': [20], 'it': [21], 'does': [22], 'not': [23], 'signal': [24], 'by': [25, 47], 'stabilizing': [26], 'beta-catenin': [27, 77], 'in': [28, 73, 79, 86], 'many': [29], 'biological': [30], 'systems.': [31], 'We': [32], 'have': [33], 'uncovered': [34], 'new': [36], 'pathway': [38, 46, 54], 'which': [40], 'antagonizes': [42], 'the': [43, 49], 'canonical': [44], 'promoting': [48], 'degradation': [50, 78], 'of': [51], 'beta-catenin.': [52], 'This': [53], 'Siah2': [56], 'and': [57, 62, 84], 'APC': [58], 'dependent,': [59], 'but': [60], 'GSK-3': [61], 'beta-TrCP': [63], 'independent.': [64], 'Furthermore,': [65], 'we': [66], 'provide': [67], 'evidence': [68], 'also': [71], 'acts': [72], 'vivo': [74], 'to': [75], 'promote': [76], 'regulating': [80], 'mammalian': [81], 'limb': [82], 'development': [83], 'possibly': [85], 'suppressing': [87], 'tumor': [88], 'formation.': [89]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2154041910', 'counts_by_year': [{'year': 2024, 'cited_by_count': 11}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 30}, {'year': 2020, 'cited_by_count': 25}, {'year': 2019, 'cited_by_count': 25}, {'year': 2018, 'cited_by_count': 25}, {'year': 2017, 'cited_by_count': 25}, {'year': 2016, 'cited_by_count': 30}, {'year': 2015, 'cited_by_count': 50}, {'year': 2014, 'cited_by_count': 39}, {'year': 2013, 'cited_by_count': 41}, {'year': 2012, 'cited_by_count': 38}], 'updated_date': '2024-12-16T15:04:28.416954', 'created_date': '2016-06-24'}