Title: Diastereoselective synthesis of γ-hydroxy-β-amino alcohols, (2S, 3S)- and (2S, 3R)-threoninol and -hydroxyphenylalaninol, from (R)-glycidol via the derived 4-hydroxymethyloxazolidinone
Abstract: Syntheses of enantiomerically pure (2S,3S)- and (2S,3R)-threoninol and (2S,3R)-hydroxyphenylalaninol are demonstrated starting from (R)-glycidol via (S)-4-methoxycarbonyl-2-oxazolidinone by monoalkylation of the ester followed by diastereoselective reduction.
Publication Year: 1994
Publication Date: 1994-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 19
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