Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2152826047', 'doi': 'https://doi.org/10.1177/1352458512444327', 'title': 'The quality of reports of randomized trials in multiple sclerosis: a review', 'display_name': 'The quality of reports of randomized trials in multiple sclerosis: a review', 'publication_year': 2012, 'publication_date': '2012-04-11', 'ids': {'openalex': 'https://openalex.org/W2152826047', 'doi': 'https://doi.org/10.1177/1352458512444327', 'mag': '2152826047', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22495947'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1177/1352458512444327', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136332993', 'display_name': 'Multiple Sclerosis Journal', 'issn_l': '1352-4585', 'issn': ['1352-4585', '1477-0970'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028388712', 'display_name': 'Alessio Signori', 'orcid': 'https://orcid.org/0000-0001-6289-9144'}, 'institutions': [{'id': 'https://openalex.org/I83816512', 'display_name': 'University of Genoa', 'ror': 'https://ror.org/0107c5v14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I83816512']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Alessio Signori', 'raw_affiliation_strings': ['Department of Health Sciences, University of Genoa, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, University of Genoa, Italy', 'institution_ids': ['https://openalex.org/I83816512']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030118088', 'display_name': 'Alice Baccino', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83816512', 'display_name': 'University of Genoa', 'ror': 'https://ror.org/0107c5v14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I83816512']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Alice Baccino', 'raw_affiliation_strings': ['Department of Health Sciences, University of Genoa, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, University of Genoa, Italy', 'institution_ids': ['https://openalex.org/I83816512']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061993323', 'display_name': 'Maria Pia Sormani', 'orcid': 'https://orcid.org/0000-0001-6892-104X'}, 'institutions': [{'id': 'https://openalex.org/I83816512', 'display_name': 'University of Genoa', 'ror': 'https://ror.org/0107c5v14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I83816512']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Maria Pia Sormani', 'raw_affiliation_strings': ['Department of Health Sciences, University of Genoa, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, University of Genoa, Italy', 'institution_ids': ['https://openalex.org/I83816512']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.456, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.381818, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 86}, 'biblio': {'volume': '18', 'issue': '6', 'first_page': '776', 'last_page': '781'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11235', 'display_name': 'Statistical Methods in Clinical Trials', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/2613', 'display_name': 'Statistics and Probability'}, 'field': {'id': 'https://openalex.org/fields/26', 'display_name': 'Mathematics'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11235', 'display_name': 'Statistical Methods in Clinical Trials', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/2613', 'display_name': 'Statistics and Probability'}, 'field': {'id': 'https://openalex.org/fields/26', 'display_name': 'Mathematics'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10206', 'display_name': 'Meta-analysis and systematic reviews', 'score': 0.9664, 'subfield': {'id': 'https://openalex.org/subfields/1804', 'display_name': 'Statistics, Probability and Uncertainty'}, 'field': {'id': 'https://openalex.org/fields/18', 'display_name': 'Decision Sciences'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, {'id': 'https://openalex.org/T10804', 'display_name': 'Health Systems, Economic Evaluations, Quality of Life', 'score': 0.9649, 'subfield': {'id': 'https://openalex.org/subfields/2002', 'display_name': 'Economics and Econometrics'}, 'field': {'id': 'https://openalex.org/fields/20', 'display_name': 'Economics, Econometrics and Finance'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/blinding', 'display_name': 'Blinding', 'score': 0.8534297}, {'id': 'https://openalex.org/keywords/subgroup-analysis', 'display_name': 'Subgroup analysis', 'score': 0.5528064}], 'concepts': [{'id': 'https://openalex.org/C2771230', 'wikidata': 'https://www.wikidata.org/wiki/Q4926699', 'display_name': 'Blinding', 'level': 3, 'score': 0.8534297}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.8003824}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.63874745}, {'id': 'https://openalex.org/C2780640218', 'wikidata': 'https://www.wikidata.org/wiki/Q8277', 'display_name': 'Multiple sclerosis', 'level': 2, 'score': 0.57486427}, {'id': 'https://openalex.org/C187960798', 'wikidata': 'https://www.wikidata.org/wiki/Q7631152', 'display_name': 'Subgroup analysis', 'level': 3, 'score': 0.5528064}, {'id': 'https://openalex.org/C204243189', 'wikidata': 'https://www.wikidata.org/wiki/Q1363085', 'display_name': 'Randomization', 'level': 3, 'score': 0.5442666}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.47869542}, {'id': 'https://openalex.org/C2779473830', 'wikidata': 'https://www.wikidata.org/wiki/Q1540899', 'display_name': 'MEDLINE', 'level': 2, 'score': 0.4212621}, {'id': 'https://openalex.org/C19527891', 'wikidata': 'https://www.wikidata.org/wiki/Q1120908', 'display_name': 'Medical physics', 'level': 1, 'score': 0.33698553}, {'id': 'https://openalex.org/C95190672', 'wikidata': 'https://www.wikidata.org/wiki/Q815382', 'display_name': 'Meta-analysis', 'level': 2, 'score': 0.20805588}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.15767074}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.13756347}, {'id': 'https://openalex.org/C17744445', 'wikidata': 'https://www.wikidata.org/wiki/Q36442', 'display_name': 'Political science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199539241', 'wikidata': 'https://www.wikidata.org/wiki/Q7748', 'display_name': 'Law', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D009103', 'descriptor_name': 'Multiple Sclerosis', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D016032', 'descriptor_name': 'Randomized Controlled Trials as Topic', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': True}, {'descriptor_ui': 'D012107', 'descriptor_name': 'Research Design', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': True}, {'descriptor_ui': 'D003627', 'descriptor_name': 'Data Interpretation, Statistical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035081', 'descriptor_name': 'Editorial Policies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023381', 'descriptor_name': 'Endpoint Determination', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': False}, {'descriptor_ui': 'D023381', 'descriptor_name': 'Endpoint Determination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019317', 'descriptor_name': 'Evidence-Based Medicine', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': False}, {'descriptor_ui': 'D019317', 'descriptor_name': 'Evidence-Based Medicine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017408', 'descriptor_name': 'Guidelines as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009103', 'descriptor_name': 'Multiple Sclerosis', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D009103', 'descriptor_name': 'Multiple Sclerosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010506', 'descriptor_name': 'Periodicals as Topic', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': False}, {'descriptor_ui': 'D010506', 'descriptor_name': 'Periodicals as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016032', 'descriptor_name': 'Randomized Controlled Trials as Topic', 'qualifier_ui': 'Q000706', 'qualifier_name': 'statistics & numerical data', 'is_major_topic': False}, {'descriptor_ui': 'D016032', 'descriptor_name': 'Randomized Controlled Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012107', 'descriptor_name': 'Research Design', 'qualifier_ui': 'Q000706', 'qualifier_name': 'statistics & numerical data', 'is_major_topic': False}, {'descriptor_ui': 'D012107', 'descriptor_name': 'Research Design', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1177/1352458512444327', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136332993', 'display_name': 'Multiple Sclerosis Journal', 'issn_l': '1352-4585', 'issn': ['1352-4585', '1477-0970'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22495947', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1501619595', 'https://openalex.org/W1828984482', 'https://openalex.org/W1968023538', 'https://openalex.org/W1977833499', 'https://openalex.org/W2021424396', 'https://openalex.org/W2022866457', 'https://openalex.org/W2049103906', 'https://openalex.org/W2060979566', 'https://openalex.org/W2062539335', 'https://openalex.org/W2074801739', 'https://openalex.org/W2078110114', 'https://openalex.org/W2095294795', 'https://openalex.org/W2099086046', 'https://openalex.org/W2108233388', 'https://openalex.org/W2108696783', 'https://openalex.org/W2117619079', 'https://openalex.org/W2118277450', 'https://openalex.org/W2121392364', 'https://openalex.org/W2142960568', 'https://openalex.org/W2144504916', 'https://openalex.org/W2153143281', 'https://openalex.org/W2165547142', 'https://openalex.org/W2185543853', 'https://openalex.org/W2340533542', 'https://openalex.org/W2795972393', 'https://openalex.org/W4210548604', 'https://openalex.org/W4233954896'], 'related_works': ['https://openalex.org/W4238788738', 'https://openalex.org/W2971237856', 'https://openalex.org/W2781743445', 'https://openalex.org/W2616226136', 'https://openalex.org/W2275660195', 'https://openalex.org/W2089908284', 'https://openalex.org/W2029114449', 'https://openalex.org/W2002981128', 'https://openalex.org/W1989626097', 'https://openalex.org/W1831094849'], 'abstract_inverted_index': {'Randomized': [0], 'clinical': [1], 'trials': [2, 162], '(RCT)': [3], 'in': [4, 31, 42, 95, 108, 148, 163], 'multiple': [5], 'sclerosis': [6], '(MS)': [7], 'have': [8], 'a': [9, 27, 71], 'recent': [10], 'tradition,': [11], 'but': [12], 'their': [13], 'number': [14], 'has': [15], 'been': [16], 'exponentially': [17], 'increasing': [18], 'since': [19], 'the': [20, 24, 35, 51, 96, 100, 109, 113, 129, 158], 'first': [21], 'study': [22], 'detecting': [23], 'efficacy': [25], 'of': [26, 38, 40, 53, 73, 99, 111, 121, 140, 160], 'disease': [28], 'modifying': [29], 'drug': [30], 'MS.': [32, 164], 'To': [33], 'examine': [34], 'methodological': [36, 77, 101], 'details': [37, 80], 'reports': [39, 52, 61, 92], 'RCT': [41, 54], 'MS,': [43], 'we': [44], 'extracted': [45], 'from': [46], 'five': [47], 'leading': [48], 'journals': [49], 'all': [50], 'published': [55], 'between': [56], '1993': [57], 'and': [58, 83, 118, 128, 137], '2010.': [59], 'Trial': [60], 'were': [62, 93], 'compared': [63], 'for': [64, 70, 124, 157], 'different': [65], 'periods': [66], '(1993–2001,': [67], '2002–2006,': [68], '2007–2010)': [69], 'set': [72], 'indicator': [74], 'variables': [75], 'reflecting': [76], 'quality': [78, 110], '(including': [79], 'about': [81], 'randomization': [82], 'blinding,': [84], 'statistical': [85, 130], 'methods,': [86], 'results': [87], 'reporting,': [88, 112], 'subgroup': [89, 133], 'analyses).': [90], 'Fifty-three': [91], 'included': [94], 'analysis.': [97, 134], 'All': [98], 'items': [102], 'indicated': [103], 'an': [104, 149], 'improvement': [105], 'over': [106], 'time': [107], 'main': [114], 'weaknesses': [115], 'being': [116], 'frequent': [117], 'inappropriate': [119], 'use': [120], 'significance': [122], 'testing': [123], 'assessing': [125], 'baseline': [126], 'imbalances': [127], 'approach': [131], 'to': [132], 'A': [135], 'complete': [136], 'transparent': [138], 'reporting': [139], 'trial': [141], 'methodology': [142], 'is': [143], 'becoming': [144], 'even': [145], 'more': [146], 'important': [147], 'era': [150], 'when': [151], 'new': [152], 'design': [153], 'strategies': [154], 'are': [155], 'required': [156], 'feasibility': [159], 'future': [161]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2152826047', 'counts_by_year': [{'year': 2018, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-13T18:53:25.753060', 'created_date': '2016-06-24'}