A Pathway-Dependent on ApoE, ApoAI, and ABCA1 Determines Formation of Buoyant High-Density Lipoprotein by Macrophage Foam Cells

Name: Work Video:
Duration: 3 min 30 s
Patricia G. Yancey; Hong Yu; MacRae F. Linton; Sergio Fazio
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152], '&gt;1.21g/mL,': [88], 'whereas': [89], '1.09': [98], 'to': [99, 209, 218], '1.17g/mL': [100], 'paralleled': [102], 'cholesterol.': [106], 'With': [107], 'apoAI,': [108, 146, 204], 'stimulation': [110], 'increased': [111], '139%': [114], '86%': [116], 'resulting': [123], 'a': [125, 215], 'large': [126], 'difference': [127], '(29.5%±0.2%': [130], 'versus': [131, 175], '17.0%±0.5%).': [132], 'The': [133], 'cholesterol': [138, 160], 'did': [142], 'not': [143], 'change': [144], 'with': [145, 195], 'most': [148], 'apoAI': [149, 158], '≥1.17g/mL.': [153], 'In': [154], 'density,': [164], 'but': [165], 'peak': [167], 'fraction': [168], 'contained': [170], '4': [171], 'μg': [172], 'cholesterol/mg': [173], 'protein': [174], '18': [176], 'WT': [178], 'cells.': [179], 'Conclusions—': [180], 'Macrophage': [181], 'requires': [183], 'for': [185], 'lipoprotein.': [189], 'ApoAI': [190], 'facilitates': [191], 'association': [192], 'more': [196], 'buoyant': [197], 'lipoprotein,': [199], 'suggesting': [200], 'that': [201], 'apoE,': [202], 'plasma': [203], 'together': [208], 'optimize': [210], 'mobilization': [211], 'macrophage': [213], 'process': [216], 'critical': [217], 'limiting': [219], 'plaque': [220], 'development.': [221]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2151211162', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-15T15:25:02.346810', 'created_date': '2016-06-24'}
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