Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2150854138', 'doi': 'https://doi.org/10.1111/iwj.12140', 'title': 'Biological properties of dehydrated human amnion/chorion composite graft: implications for chronic wound healing', 'display_name': 'Biological properties of dehydrated human amnion/chorion composite graft: implications for chronic wound healing', 'publication_year': 2013, 'publication_date': '2013-08-01', 'ids': {'openalex': 'https://openalex.org/W2150854138', 'doi': 'https://doi.org/10.1111/iwj.12140', 'mag': '2150854138', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23902526', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4228928'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/iwj.12140', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/iwj.12140', 'source': {'id': 'https://openalex.org/S118780703', 'display_name': 'International Wound Journal', 'issn_l': '1742-4801', 'issn': ['1742-4801', '1742-481X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/iwj.12140', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5046932964', 'display_name': 'Thomas J. Koob', 'orcid': 'https://orcid.org/0000-0001-6162-4202'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Thomas J Koob', 'raw_affiliation_strings': ['MiMedx Group, Inc., Marietta, GA, USA'], 'affiliations': [{'raw_affiliation_string': 'MiMedx Group, Inc., Marietta, GA, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102936845', 'display_name': 'Robert C. Rennert', 'orcid': 'https://orcid.org/0000-0001-6779-3592'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert Rennert', 'raw_affiliation_strings': ['Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041188105', 'display_name': 'Nicole Zabek', 'orcid': None}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nicole Zabek', 'raw_affiliation_strings': ['MiMedx Group, Inc., Marietta, GA, USA'], 'affiliations': [{'raw_affiliation_string': 'MiMedx Group, Inc., Marietta, GA, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056961606', 'display_name': 'Michelle Massee', 'orcid': 'https://orcid.org/0000-0001-9025-0879'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michelle Massee', 'raw_affiliation_strings': ['MiMedx Group, Inc., Marietta, GA, USA'], 'affiliations': [{'raw_affiliation_string': 'MiMedx Group, Inc., Marietta, GA, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063420325', 'display_name': 'Jeremy J. Lim', 'orcid': 'https://orcid.org/0000-0002-6424-2696'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jeremy J Lim', 'raw_affiliation_strings': ['MiMedx Group, Inc., Marietta, GA, USA'], 'affiliations': [{'raw_affiliation_string': 'MiMedx Group, Inc., Marietta, GA, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048802181', 'display_name': 'Johnna S. Temenoff', 'orcid': 'https://orcid.org/0000-0002-9066-7954'}, 'institutions': [{'id': 'https://openalex.org/I2802612298', 'display_name': 'The Wallace H. Coulter Department of Biomedical Engineering', 'ror': 'https://ror.org/02j15s898', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130701444', 'https://openalex.org/I150468666', 'https://openalex.org/I2802612298']}, {'id': 'https://openalex.org/I130701444', 'display_name': 'Georgia Institute of Technology', 'ror': 'https://ror.org/01zkghx44', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130701444']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Johnna S Temenoff', 'raw_affiliation_strings': ['Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA'], 'affiliations': [{'raw_affiliation_string': 'Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA', 'institution_ids': ['https://openalex.org/I2802612298', 'https://openalex.org/I130701444']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025408245', 'display_name': 'William W. Li', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800764247', 'display_name': 'Angiogenesis Foundation', 'ror': 'https://ror.org/00ww7tv14', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2800764247']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'William W Li', 'raw_affiliation_strings': ['The Angiogenesis Foundation, Cambridge, MA, USA'], 'affiliations': [{'raw_affiliation_string': 'The Angiogenesis Foundation, Cambridge, MA, USA', 'institution_ids': ['https://openalex.org/I2800764247']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009803821', 'display_name': 'Geoffrey C. Gurtner', 'orcid': 'https://orcid.org/0000-0001-6118-7161'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Geoffrey Gurtner', 'raw_affiliation_strings': ['Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, CA, USA', 'institution_ids': ['https://openalex.org/I97018004']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5046932964'], 'corresponding_institution_ids': [], 'apc_list': {'value': 2532, 'currency': 'USD', 'value_usd': 2532, 'provenance': 'doaj'}, 'apc_paid': {'value': 2532, 'currency': 'USD', 'value_usd': 2532, 'provenance': 'doaj'}, 'fwci': 12.415, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 269, 'citation_normalized_percentile': {'value': 0.939563, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '10', 'issue': '5', 'first_page': '493', 'last_page': '500'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11828', 'display_name': 'Corneal Tissue Engineering and Regeneration', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11828', 'display_name': 'Corneal Tissue Engineering and Regeneration', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10771', 'display_name': 'Wound Healing and Regeneration', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11966', 'display_name': 'Biomedical Applications of Silk Biomaterials', 'score': 0.9935, 'subfield': {'id': 'https://openalex.org/subfields/2502', 'display_name': 'Biomaterials'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/amnion', 'display_name': 'Amnion', 'score': 0.74449635}, {'id': 'https://openalex.org/keywords/growth-factors', 'display_name': 'Growth Factors', 'score': 0.490571}, {'id': 'https://openalex.org/keywords/keratinocyte-growth-factor', 'display_name': 'Keratinocyte growth factor', 'score': 0.4528443}], 'concepts': [{'id': 'https://openalex.org/C2780646683', 'wikidata': 'https://www.wikidata.org/wiki/Q473749', 'display_name': 'Amnion', 'level': 4, 'score': 0.74449635}, {'id': 'https://openalex.org/C2780269544', 'wikidata': 'https://www.wikidata.org/wiki/Q1509074', 'display_name': 'Wound healing', 'level': 2, 'score': 0.72334915}, {'id': 'https://openalex.org/C198826908', 'wikidata': 'https://www.wikidata.org/wiki/Q1922379', 'display_name': 'Mesenchymal stem cell', 'level': 2, 'score': 0.6914754}, {'id': 'https://openalex.org/C2777587049', 'wikidata': 'https://www.wikidata.org/wiki/Q20969945', 'display_name': 'Basic fibroblast growth factor', 'level': 4, 'score': 0.6304883}, {'id': 'https://openalex.org/C2775960820', 'wikidata': 'https://www.wikidata.org/wiki/Q408378', 'display_name': 'Growth factor', 'level': 3, 'score': 0.62243307}, {'id': 'https://openalex.org/C2776362946', 'wikidata': 'https://www.wikidata.org/wiki/Q424374', 'display_name': 'Epidermal growth factor', 'level': 3, 'score': 0.6138125}, {'id': 'https://openalex.org/C118131993', 'wikidata': 'https://www.wikidata.org/wiki/Q423671', 'display_name': 'Transforming growth factor', 'level': 2, 'score': 0.56730723}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.54914767}, {'id': 'https://openalex.org/C74373430', 'wikidata': 'https://www.wikidata.org/wiki/Q24727126', 'display_name': 'Fibroblast growth factor', 'level': 3, 'score': 0.54762024}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.5451663}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.54147255}, {'id': 'https://openalex.org/C2778615670', 'wikidata': 'https://www.wikidata.org/wiki/Q3811988', 'display_name': 'Keratinocyte growth factor', 'level': 4, 'score': 0.4528443}, {'id': 'https://openalex.org/C180361614', 'wikidata': 'https://www.wikidata.org/wiki/Q7202242', 'display_name': 'Platelet-derived growth factor receptor', 'level': 4, 'score': 0.4446062}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.43620265}, {'id': 'https://openalex.org/C201750760', 'wikidata': 'https://www.wikidata.org/wiki/Q1896218', 'display_name': 'Progenitor cell', 'level': 3, 'score': 0.42415458}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.33774963}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.3368952}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2354157}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.20716223}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.20493144}, {'id': 'https://openalex.org/C172680121', 'wikidata': 'https://www.wikidata.org/wiki/Q26513', 'display_name': 'Fetus', 'level': 3, 'score': 0.10232586}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000650', 'descriptor_name': 'Amnion', 'qualifier_ui': 'Q000637', 'qualifier_name': 'transplantation', 'is_major_topic': True}, {'descriptor_ui': 'D002823', 'descriptor_name': 'Chorion', 'qualifier_ui': 'Q000637', 'qualifier_name': 'transplantation', 'is_major_topic': True}, {'descriptor_ui': 'D059630', 'descriptor_name': 'Mesenchymal Stem Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D033581', 'descriptor_name': 'Stem Cell Transplantation', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D009927', 'descriptor_name': 'Tissue and Organ Procurement', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D014945', 'descriptor_name': 'Wound Healing', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D014947', 'descriptor_name': 'Wounds and Injuries', 'qualifier_ui': 'Q000601', 'qualifier_name': 'surgery', 'is_major_topic': True}, {'descriptor_ui': 'D000650', 'descriptor_name': 'Amnion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000650', 'descriptor_name': 'Amnion', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002823', 'descriptor_name': 'Chorion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002823', 'descriptor_name': 'Chorion', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D002908', 'descriptor_name': 'Chronic Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003681', 'descriptor_name': 'Dehydration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059630', 'descriptor_name': 'Mesenchymal Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D033581', 'descriptor_name': 'Stem Cell Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009927', 'descriptor_name': 'Tissue and Organ Procurement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014945', 'descriptor_name': 'Wound Healing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014947', 'descriptor_name': 'Wounds and Injuries', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014947', 'descriptor_name': 'Wounds and Injuries', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014947', 'descriptor_name': 'Wounds and Injuries', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/iwj.12140', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/iwj.12140', 'source': {'id': 'https://openalex.org/S118780703', 'display_name': 'International Wound Journal', 'issn_l': '1742-4801', 'issn': ['1742-4801', '1742-481X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4228928', 'pdf_url': 'https://europepmc.org/articles/pmc4228928?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228928', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23902526', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/iwj.12140', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/iwj.12140', 'source': {'id': 'https://openalex.org/S118780703', 'display_name': 'International Wound Journal', 'issn_l': '1742-4801', 'issn': ['1742-4801', '1742-481X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.49}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W129305155', 'https://openalex.org/W1573296762', 'https://openalex.org/W1800576749', 'https://openalex.org/W1870482595', 'https://openalex.org/W1949832432', 'https://openalex.org/W1965560753', 'https://openalex.org/W1969716818', 'https://openalex.org/W1970794616', 'https://openalex.org/W1970964721', 'https://openalex.org/W1975231119', 'https://openalex.org/W1975667857', 'https://openalex.org/W2004418591', 'https://openalex.org/W2007409518', 'https://openalex.org/W2018540691', 'https://openalex.org/W2021489532', 'https://openalex.org/W2053406714', 'https://openalex.org/W2056235630', 'https://openalex.org/W2058460635', 'https://openalex.org/W2069014648', 'https://openalex.org/W2074016493', 'https://openalex.org/W2084565323', 'https://openalex.org/W2086012829', 'https://openalex.org/W2095132685', 'https://openalex.org/W2110541594', 'https://openalex.org/W2120500721', 'https://openalex.org/W2126067465', 'https://openalex.org/W2137487929', 'https://openalex.org/W2159634847', 'https://openalex.org/W66624148'], 'related_works': ['https://openalex.org/W80164971', 'https://openalex.org/W318183733', 'https://openalex.org/W3031715957', 'https://openalex.org/W2388082204', 'https://openalex.org/W2348536875', 'https://openalex.org/W2054269366', 'https://openalex.org/W2008791580', 'https://openalex.org/W1980398407', 'https://openalex.org/W1562279196', 'https://openalex.org/W1512484541'], 'abstract_inverted_index': {'Human': [0], 'amnion/chorion': [1, 43], 'tissue': [2, 44, 60], 'derived': [3], 'from': [4, 141, 145, 210], 'the': [5, 22, 52, 80, 118, 133, 142, 161, 204, 212, 250], 'placenta': [6], 'is': [7], 'rich': [8], 'in': [9, 181, 184, 193, 213, 216, 263], 'cytokines': [10], 'and': [11, 59, 75, 108, 124, 126, 130, 154, 173, 215, 234, 257, 271], 'growth': [12, 55, 82, 85, 90, 97, 101, 105, 137], 'factors': [13, 138, 228], 'known': [14], 'to': [15, 147, 203, 246, 252], 'promote': [16], 'wound': [17, 247, 264, 288], 'healing;': [18], 'however,': [19], 'preservation': [20], 'of': [21, 25, 54, 62, 73, 79, 120, 136, 157, 175, 206, 230, 273, 281], 'biological': [23, 165, 243], 'activities': [24, 166, 244], 'therapeutic': [26], 'allografts': [27, 45], 'during': [28], 'processing': [29], 'remains': [30], 'a': [31, 194, 278], 'challenge.': [32], 'In': [33, 236], 'this': [34], 'study,': [35], 'PURION®': [36, 238], '(MiMedx,': [37], 'Marietta,': [38], 'GA)': [39], 'processed': [40, 239], 'dehydrated': [41], 'human': [42, 169, 176], '(dHACM,': [46], 'EpiFix®,': [47], 'MiMedx)': [48], 'were': [49, 69], 'evaluated': [50], 'for': [51, 283, 287], 'presence': [53, 119], 'factors,': [56], 'interleukins': [57], '(ILs)': [58], 'inhibitors': [61], 'metalloproteinases': [63], '(TIMPs).': [64], 'Enzyme-linked': [65], 'immunosorbent': [66], 'assays': [67, 115], '(ELISA)': [68], 'performed': [70], 'on': [71], 'samples': [72], 'dHACM': [74, 163, 190, 222, 240, 284], 'showed': [76, 188], 'quantifiable': [77], 'levels': [78], 'following': [81], 'factors:': [83], 'platelet-derived': [84], 'factor-AA': [86], '(PDGF-AA),': [87], 'PDGF-BB,': [88], 'transforming': [89], 'factor': [91, 98, 102, 106, 111], 'α': [92], '(TGFα),': [93], 'TGFβ1,': [94], 'basic': [95], 'fibroblast': [96, 171], '(bFGF),': [99], 'epidermal': [100], '(EGF),': [103], 'placental': [104], '(PLGF)': [107], 'granulocyte': [109], 'colony-stimulating': [110], '(GCSF).': [112], 'The': [113, 208], 'ELISA': [114], 'also': [116], 'confirmed': [117], 'IL-4,': [121], '6,': [122], '8': [123], '10,': [125], 'TIMP': [127], '1,': [128], '2': [129], '4.': [131], 'Moreover,': [132], 'relative': [134], 'elution': [135], 'into': [139], 'saline': [140], 'allograft': [143], 'ranged': [144], '4%': [146], '62%,': [148], 'indicating': [149], 'that': [150, 167, 189, 221], 'there': [151], 'are': [152], 'bound': [153], 'unbound': [155], 'fractions': [156], 'these': [158], 'compounds': [159], 'within': [160], 'allograft.': [162], 'retained': [164], 'cause': [168], 'dermal': [170], 'proliferation': [172], 'migration': [174, 233], 'mesenchymal': [177, 199], 'stem': [178], 'cells': [179], '(MSCs)': [180], 'vitro.': [182], 'An': [183], 'vivo': [185, 217], 'mouse': [186], 'model': [187, 197], 'when': [191, 285], 'tested': [192], 'skin': [195], 'flap': [196], 'caused': [198], 'progenitor': [200, 274], 'cell': [201, 266], 'recruitment': [202, 272], 'site': [205], 'implantation.': [207], 'results': [209], 'both': [211], 'vitro': [214], 'experiments': [218], 'clearly': [219], 'established': [220], 'contains': [223], 'one': [224], 'or': [225], 'more': [226], 'soluble': [227], 'capable': [229], 'stimulating': [231], 'MSC': [232], 'recruitment.': [235], 'summary,': [237], 'retains': [241], 'its': [242], 'related': [245], 'healing,': [248], 'including': [249], 'potential': [251], 'positively': [253], 'affect': [254], 'four': [255], 'distinct': [256], 'pivotal': [258], 'physiological': [259], 'processes': [260], 'intimately': [261], 'involved': [262], 'healing:': [265], 'proliferation,': [267], 'inflammation,': [268], 'metalloproteinase': [269], 'activity': [270], 'cells.': [275], 'This': [276], 'suggests': [277], 'paracrine': [279], 'mechanism': [280], 'action': [282], 'used': [286], 'healing': [289], 'applications.': [290]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2150854138', 'counts_by_year': [{'year': 2024, 'cited_by_count': 14}, {'year': 2023, 'cited_by_count': 21}, {'year': 2022, 'cited_by_count': 30}, {'year': 2021, 'cited_by_count': 33}, {'year': 2020, 'cited_by_count': 37}, {'year': 2019, 'cited_by_count': 31}, {'year': 2018, 'cited_by_count': 20}, {'year': 2017, 'cited_by_count': 29}, {'year': 2016, 'cited_by_count': 22}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 13}], 'updated_date': '2024-09-13T10:55:49.716576', 'created_date': '2016-06-24'}