Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2150655309', 'doi': 'https://doi.org/10.1056/nejmoa1300815', 'title': 'Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events', 'display_name': 'Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events', 'publication_year': 2013, 'publication_date': '2013-03-10', 'ids': {'openalex': 'https://openalex.org/W2150655309', 'doi': 'https://doi.org/10.1056/nejmoa1300815', 'mag': '2150655309', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23473369'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1300815', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1300815?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1300815?articleTools=true', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5010571732', 'display_name': 'Deepak L. Bhatt', 'orcid': 'https://orcid.org/0000-0002-1278-6245'}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I2801671727', 'display_name': 'VA Boston Healthcare System', 'ror': 'https://ror.org/04v00sg98', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I2801671727', 'https://openalex.org/I4210095851']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Deepak L. Bhatt', 'raw_affiliation_strings': ["VA Boston Healthcare System, Brigham and Women's Hospital, and Harvard Medical School, Boston"], 'affiliations': [{'raw_affiliation_string': "VA Boston Healthcare System, Brigham and Women's Hospital, and Harvard Medical School, Boston", 'institution_ids': ['https://openalex.org/I1283280774', 'https://openalex.org/I136199984', 'https://openalex.org/I2801671727']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046629853', 'display_name': 'Gregg W. Stone', 'orcid': 'https://orcid.org/0000-0002-3416-8210'}, 'institutions': [{'id': 'https://openalex.org/I2799503643', 'display_name': 'Columbia University Irving Medical Center', 'ror': 'https://ror.org/01esghr10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799503643']}, {'id': 'https://openalex.org/I4210144653', 'display_name': 'Cardiovascular Research Foundation', 'ror': 'https://ror.org/04yxwc698', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210144653']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gregg W. Stone', 'raw_affiliation_strings': ['Columbia University Medical Center and the Cardiovascular Research Foundation, New York'], 'affiliations': [{'raw_affiliation_string': 'Columbia University Medical Center and the Cardiovascular Research Foundation, New York', 'institution_ids': ['https://openalex.org/I2799503643', 'https://openalex.org/I4210144653']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039432822', 'display_name': 'Kenneth W. Mahaffey', 'orcid': 'https://orcid.org/0000-0002-3791-2148'}, 'institutions': [{'id': 'https://openalex.org/I4210088741', 'display_name': 'Clinical Research Institute', 'ror': 'https://ror.org/009ywjj88', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210088741']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kenneth W. Mahaffey', 'raw_affiliation_strings': ['Duke Clinical Research Institute, Durham, NC'], 'affiliations': [{'raw_affiliation_string': 'Duke Clinical Research Institute, Durham, NC', 'institution_ids': ['https://openalex.org/I4210088741']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007026783', 'display_name': 'C. Michael Gibson', 'orcid': 'https://orcid.org/0000-0002-4857-9125'}, 'institutions': [{'id': 'https://openalex.org/I2799899409', 'display_name': 'Hadassah Medical Center', 'ror': 'https://ror.org/01cqmqj90', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799899409']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'C. Michael Gibson', 'raw_affiliation_strings': ['Beth Israel Deaconess Medical Center, Division of Cardiology, Boston'], 'affiliations': [{'raw_affiliation_string': 'Beth Israel Deaconess Medical Center, Division of Cardiology, Boston', 'institution_ids': ['https://openalex.org/I2799899409']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003831287', 'display_name': 'Philippe Gabríel Steg', 'orcid': 'https://orcid.org/0000-0001-6896-2941'}, 'institutions': [{'id': 'https://openalex.org/I169173203', 'display_name': 'Délégation Paris 7', 'ror': 'https://ror.org/00bw5n526', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I169173203']}, {'id': 'https://openalex.org/I4210097159', 'display_name': 'Assistance Publique – Hôpitaux de Paris', 'ror': 'https://ror.org/00pg5jh14', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}, {'id': 'https://openalex.org/I4210145170', 'display_name': 'Hôpital Bichat-Claude-Bernard', 'ror': 'https://ror.org/03fdnmv92', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210145170']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'P. Gabriel Steg', 'raw_affiliation_strings': ['INSERM Unité 698, Université Paris-Diderot, and Hôpital Bichat, Assistance-Publique–Hôpitaux de Paris, Paris'], 'affiliations': [{'raw_affiliation_string': 'INSERM Unité 698, Université Paris-Diderot, and Hôpital Bichat, Assistance-Publique–Hôpitaux de Paris, Paris', 'institution_ids': ['https://openalex.org/I169173203', 'https://openalex.org/I4210097159', 'https://openalex.org/I154526488', 'https://openalex.org/I204730241', 'https://openalex.org/I4210145170']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010936003', 'display_name': 'Christian W. Hamm', 'orcid': 'https://orcid.org/0000-0001-6763-4161'}, 'institutions': [{'id': 'https://openalex.org/I4210133626', 'display_name': 'Kerckhoff Klinik', 'ror': 'https://ror.org/04m54m956', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133626']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Christian W. Hamm', 'raw_affiliation_strings': ['Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany'], 'affiliations': [{'raw_affiliation_string': 'Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany', 'institution_ids': ['https://openalex.org/I4210133626']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069820090', 'display_name': 'Matthew J. Price', 'orcid': 'https://orcid.org/0000-0002-7892-2430'}, 'institutions': [{'id': 'https://openalex.org/I4210146328', 'display_name': 'Scripps Clinic', 'ror': 'https://ror.org/05kwjwj05', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1311914864', 'https://openalex.org/I4210146328']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Matthew J. Price', 'raw_affiliation_strings': ['Scripps Clinic and Scripps Translational Science Institute, La Jolla, CA'], 'affiliations': [{'raw_affiliation_string': 'Scripps Clinic and Scripps Translational Science Institute, La Jolla, CA', 'institution_ids': ['https://openalex.org/I4210146328']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065883685', 'display_name': 'Sergio Leonardi', 'orcid': 'https://orcid.org/0000-0002-4800-6132'}, 'institutions': [{'id': 'https://openalex.org/I4210151645', 'display_name': 'Policlinico San Matteo Fondazione', 'ror': 'https://ror.org/05w1q1c88', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151645', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Sergio Leonardi', 'raw_affiliation_strings': ['Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy'], 'affiliations': [{'raw_affiliation_string': 'Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy', 'institution_ids': ['https://openalex.org/I4210151645', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050920163', 'display_name': 'Dianne Gallup', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210088741', 'display_name': 'Clinical Research Institute', 'ror': 'https://ror.org/009ywjj88', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210088741']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dianne Gallup', 'raw_affiliation_strings': ['Duke Clinical Research Institute, Durham, NC'], 'affiliations': [{'raw_affiliation_string': 'Duke Clinical Research Institute, Durham, NC', 'institution_ids': ['https://openalex.org/I4210088741']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003053153', 'display_name': 'Ezio Bramucci', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151645', 'display_name': 'Policlinico San Matteo Fondazione', 'ror': 'https://ror.org/05w1q1c88', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151645', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Ezio Bramucci', 'raw_affiliation_strings': ['Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy'], 'affiliations': [{'raw_affiliation_string': 'Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy', 'institution_ids': ['https://openalex.org/I4210151645', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042795574', 'display_name': 'Peter W. Radke', 'orcid': 'https://orcid.org/0000-0001-8948-1565'}, 'institutions': [{'id': 'https://openalex.org/I4210112713', 'display_name': 'University Hospital Schleswig-Holstein', 'ror': 'https://ror.org/01tvm6f46', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210112713']}, {'id': 'https://openalex.org/I9341345', 'display_name': 'University of Lübeck', 'ror': 'https://ror.org/00t3r8h32', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I9341345']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Peter W. Radke', 'raw_affiliation_strings': ['Universitätsklinikum Schleswig-Holstein, Lübeck, Germany'], 'affiliations': [{'raw_affiliation_string': 'Universitätsklinikum Schleswig-Holstein, Lübeck, Germany', 'institution_ids': ['https://openalex.org/I4210112713', 'https://openalex.org/I9341345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108266498', 'display_name': 'Petr Widimský', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210156160', 'display_name': 'University Hospital Kralovske Vinohrady', 'ror': 'https://ror.org/04sg4ka71', 'country_code': 'CZ', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210156160']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'Petr Widimský', 'raw_affiliation_strings': ['Fakultni Nemocnice Kralovske Vinohrady, Prague'], 'affiliations': [{'raw_affiliation_string': 'Fakultni Nemocnice Kralovske Vinohrady, Prague', 'institution_ids': ['https://openalex.org/I4210156160']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061794482', 'display_name': 'František Toušek', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210127559', 'display_name': 'Nemocnice České Budějovice', 'ror': 'https://ror.org/02zwjz895', 'country_code': 'CZ', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127559']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'Frantisek Tousek', 'raw_affiliation_strings': ['Nemocnice Ceske Budejovice, Ceske Budejovice'], 'affiliations': [{'raw_affiliation_string': 'Nemocnice Ceske Budejovice, Ceske Budejovice', 'institution_ids': ['https://openalex.org/I4210127559']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091126928', 'display_name': 'Jeffrey Tauth', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210088060', 'display_name': 'Ark Medical Center', 'ror': 'https://ror.org/002bpyg81', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088060']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jeffrey Tauth', 'raw_affiliation_strings': ['National Park Medical Center, Hot Springs, AR'], 'affiliations': [{'raw_affiliation_string': 'National Park Medical Center, Hot Springs, AR', 'institution_ids': ['https://openalex.org/I4210088060']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114051272', 'display_name': 'Douglas Spriggs', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Douglas Spriggs', 'raw_affiliation_strings': ['Clearwater Cardiovascular and Interventional Consultants, Clearwater, FL'], 'affiliations': [{'raw_affiliation_string': 'Clearwater Cardiovascular and Interventional Consultants, Clearwater, FL', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074461963', 'display_name': 'Brent McLaurin', 'orcid': 'https://orcid.org/0000-0002-5561-6107'}, 'institutions': [{'id': 'https://openalex.org/I4210103635', 'display_name': 'AnMed Health', 'ror': 'https://ror.org/019ph5n64', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103635']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Brent T. McLaurin', 'raw_affiliation_strings': ['AnMed Health, Anderson, SC'], 'affiliations': [{'raw_affiliation_string': 'AnMed Health, Anderson, SC', 'institution_ids': ['https://openalex.org/I4210103635']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040418600', 'display_name': 'Dominick J. Angiolillo', 'orcid': 'https://orcid.org/0000-0001-8451-2131'}, 'institutions': [{'id': 'https://openalex.org/I94062374', 'display_name': 'Florida College', 'ror': 'https://ror.org/010bgev76', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I94062374']}, {'id': 'https://openalex.org/I33213144', 'display_name': 'University of Florida', 'ror': 'https://ror.org/02y3ad647', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I33213144']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dominick J. Angiolillo', 'raw_affiliation_strings': ['University of Florida College of Medicine, Jacksonville'], 'affiliations': [{'raw_affiliation_string': 'University of Florida College of Medicine, Jacksonville', 'institution_ids': ['https://openalex.org/I94062374', 'https://openalex.org/I33213144']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007377189', 'display_name': 'Philippe Généreux', 'orcid': 'https://orcid.org/0000-0002-5507-3712'}, 'institutions': [{'id': 'https://openalex.org/I2799503643', 'display_name': 'Columbia University Irving Medical Center', 'ror': 'https://ror.org/01esghr10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799503643']}, {'id': 'https://openalex.org/I4210144653', 'display_name': 'Cardiovascular Research Foundation', 'ror': 'https://ror.org/04yxwc698', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210144653']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Philippe Généreux', 'raw_affiliation_strings': ['Columbia University Medical Center and the Cardiovascular Research Foundation, New York'], 'affiliations': [{'raw_affiliation_string': 'Columbia University Medical Center and the Cardiovascular Research Foundation, New York', 'institution_ids': ['https://openalex.org/I2799503643', 'https://openalex.org/I4210144653']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065179446', 'display_name': 'Tiepu Liu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I203980794', 'display_name': 'Doctors Company (United States)', 'ror': 'https://ror.org/03xm3wq50', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I203980794']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tiepu Liu', 'raw_affiliation_strings': ['Medicines Company, Parsippany, NJ'], 'affiliations': [{'raw_affiliation_string': 'Medicines Company, Parsippany, NJ', 'institution_ids': ['https://openalex.org/I203980794']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086306721', 'display_name': 'Jayne Prats', 'orcid': 'https://orcid.org/0000-0003-2146-9820'}, 'institutions': [{'id': 'https://openalex.org/I203980794', 'display_name': 'Doctors Company (United States)', 'ror': 'https://ror.org/03xm3wq50', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I203980794']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jayne Prats', 'raw_affiliation_strings': ['Medicines Company, Parsippany, NJ'], 'affiliations': [{'raw_affiliation_string': 'Medicines Company, Parsippany, NJ', 'institution_ids': ['https://openalex.org/I203980794']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059307070', 'display_name': 'Meredith Todd', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I203980794', 'display_name': 'Doctors Company (United States)', 'ror': 'https://ror.org/03xm3wq50', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I203980794']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Meredith Todd', 'raw_affiliation_strings': ['Medicines Company, Parsippany, NJ'], 'affiliations': [{'raw_affiliation_string': 'Medicines Company, Parsippany, NJ', 'institution_ids': ['https://openalex.org/I203980794']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040235019', 'display_name': 'Simona Skerjanec', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I203980794', 'display_name': 'Doctors Company (United States)', 'ror': 'https://ror.org/03xm3wq50', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I203980794']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Simona Skerjanec', 'raw_affiliation_strings': ['Medicines Company, Parsippany, NJ'], 'affiliations': [{'raw_affiliation_string': 'Medicines Company, Parsippany, NJ', 'institution_ids': ['https://openalex.org/I203980794']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062843291', 'display_name': 'Harvey D. White', 'orcid': 'https://orcid.org/0000-0001-7712-6750'}, 'institutions': [{'id': 'https://openalex.org/I4210093388', 'display_name': 'Greenlane Clinical Centre', 'ror': 'https://ror.org/00envkz24', 'country_code': 'NZ', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093388', 'https://openalex.org/I4210114327']}], 'countries': ['NZ'], 'is_corresponding': False, 'raw_author_name': 'Harvey D. White', 'raw_affiliation_strings': ['Green Lane Cardiovascular Service, Auckland, New Zealand'], 'affiliations': [{'raw_affiliation_string': 'Green Lane Cardiovascular Service, Auckland, New Zealand', 'institution_ids': ['https://openalex.org/I4210093388']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060370891', 'display_name': 'Robert A. Harrington', 'orcid': 'https://orcid.org/0000-0001-5450-8676'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert A. Harrington', 'raw_affiliation_strings': ['Stanford University Medical School, Stanford, CA'], 'affiliations': [{'raw_affiliation_string': 'Stanford University Medical School, Stanford, CA', 'institution_ids': ['https://openalex.org/I97018004']}]}], 'institution_assertions': [], 'countries_distinct_count': 7, 'institutions_distinct_count': 27, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 67.724, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 769, 'citation_normalized_percentile': {'value': 0.999959, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '368', 'issue': '14', 'first_page': '1303', 'last_page': '1313'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10193', 'display_name': 'Coronary Interventions and Diagnostics', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10292', 'display_name': 'Acute Myocardial Infarction Research', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cangrelor', 'display_name': 'Cangrelor', 'score': 0.9913859}, {'id': 'https://openalex.org/keywords/adenosine-receptor-antagonist', 'display_name': 'Adenosine receptor antagonist', 'score': 0.6318903}, {'id': 'https://openalex.org/keywords/adenosine-diphosphate', 'display_name': 'Adenosine diphosphate', 'score': 0.47318745}], 'concepts': [{'id': 'https://openalex.org/C2776708134', 'wikidata': 'https://www.wikidata.org/wiki/Q3655338', 'display_name': 'Cangrelor', 'level': 5, 'score': 0.9913859}, {'id': 'https://openalex.org/C45393284', 'wikidata': 'https://www.wikidata.org/wiki/Q191012', 'display_name': 'Conventional PCI', 'level': 3, 'score': 0.93127906}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9199809}, {'id': 'https://openalex.org/C2780400711', 'wikidata': 'https://www.wikidata.org/wiki/Q2008344', 'display_name': 'Percutaneous coronary intervention', 'level': 3, 'score': 0.8521727}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.63651794}, {'id': 'https://openalex.org/C2780634109', 'wikidata': 'https://www.wikidata.org/wiki/Q18350222', 'display_name': 'Adenosine receptor antagonist', 'level': 5, 'score': 0.6318903}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.5884998}, {'id': 'https://openalex.org/C2776991684', 'wikidata': 'https://www.wikidata.org/wiki/Q190012', 'display_name': 'Adenosine', 'level': 2, 'score': 0.58348334}, {'id': 'https://openalex.org/C49059817', 'wikidata': 'https://www.wikidata.org/wiki/Q14916330', 'display_name': 'P2Y12', 'level': 4, 'score': 0.5162963}, {'id': 'https://openalex.org/C2777399203', 'wikidata': 'https://www.wikidata.org/wiki/Q185253', 'display_name': 'Adenosine diphosphate', 'level': 4, 'score': 0.47318745}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.46506196}, {'id': 'https://openalex.org/C89560881', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet', 'level': 2, 'score': 0.41340083}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3967032}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.3878402}, {'id': 'https://openalex.org/C2993802102', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet aggregation', 'level': 3, 'score': 0.32159668}, {'id': 'https://openalex.org/C67907053', 'wikidata': 'https://www.wikidata.org/wiki/Q356147', 'display_name': 'Adenosine receptor', 'level': 4, 'score': 0.2830398}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.25915313}, {'id': 'https://openalex.org/C500558357', 'wikidata': 'https://www.wikidata.org/wiki/Q12152', 'display_name': 'Myocardial infarction', 'level': 2, 'score': 0.16253316}, {'id': 'https://openalex.org/C2778938600', 'wikidata': 'https://www.wikidata.org/wiki/Q389934', 'display_name': 'Agonist', 'level': 3, 'score': 0.08064419}], 'mesh': [{'descriptor_ui': 'D000249', 'descriptor_name': 'Adenosine Monophosphate', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D015906', 'descriptor_name': 'Angioplasty, Balloon, Coronary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017202', 'descriptor_name': 'Myocardial Ischemia', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015607', 'descriptor_name': 'Stents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D013927', 'descriptor_name': 'Thrombosis', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D013988', 'descriptor_name': 'Ticlopidine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D000249', 'descriptor_name': 'Adenosine Monophosphate', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000249', 'descriptor_name': 'Adenosine Monophosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000249', 'descriptor_name': 'Adenosine Monophosphate', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015906', 'descriptor_name': 'Angioplasty, Balloon, Coronary', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000077144', 'descriptor_name': 'Clopidogrel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057194', 'descriptor_name': 'Intention to Treat Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053208', 'descriptor_name': 'Kaplan-Meier Estimate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017202', 'descriptor_name': 'Myocardial Ischemia', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D017202', 'descriptor_name': 'Myocardial Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D015607', 'descriptor_name': 'Stents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013927', 'descriptor_name': 'Thrombosis', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D013927', 'descriptor_name': 'Thrombosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013988', 'descriptor_name': 'Ticlopidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013988', 'descriptor_name': 'Ticlopidine', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D013988', 'descriptor_name': 'Ticlopidine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1300815', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1300815?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23473369', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1300815', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1300815?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.84, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1591285', 'https://openalex.org/W1963879877', 'https://openalex.org/W1965705149', 'https://openalex.org/W1973410511', 'https://openalex.org/W1978591428', 'https://openalex.org/W1982658190', 'https://openalex.org/W1991096813', 'https://openalex.org/W1995259829', 'https://openalex.org/W2018234502', 'https://openalex.org/W2032783186', 'https://openalex.org/W2038475174', 'https://openalex.org/W2050027713', 'https://openalex.org/W2050043025', 'https://openalex.org/W2053379248', 'https://openalex.org/W2065390746', 'https://openalex.org/W2071686230', 'https://openalex.org/W2073008923', 'https://openalex.org/W2077401512', 'https://openalex.org/W2090210165', 'https://openalex.org/W2096002945', 'https://openalex.org/W2102951688', 'https://openalex.org/W2111440117', 'https://openalex.org/W2133924558', 'https://openalex.org/W2136228924', 'https://openalex.org/W2138733869', 'https://openalex.org/W2140501627', 'https://openalex.org/W2144206796', 'https://openalex.org/W2153447053', 'https://openalex.org/W2157833432', 'https://openalex.org/W2169387542', 'https://openalex.org/W2170949977', 'https://openalex.org/W2470272844', 'https://openalex.org/W55856558'], 'related_works': ['https://openalex.org/W4311497569', 'https://openalex.org/W4311331586', 'https://openalex.org/W3111251731', 'https://openalex.org/W2555533664', 'https://openalex.org/W2413803679', 'https://openalex.org/W2313052852', 'https://openalex.org/W2186379476', 'https://openalex.org/W2150655309', 'https://openalex.org/W2145062078', 'https://openalex.org/W2006287575'], 'abstract_inverted_index': {'The': [0, 79, 112, 156, 213, 243], 'intensity': [1], 'of': [2, 14, 63, 71, 77, 87, 124, 158, 190, 215, 264], 'antiplatelet': [3], 'therapy': [4, 56], 'during': [5, 270], 'percutaneous': [6], 'coronary': [7], 'intervention': [8], '(PCI)': [9], 'is': [10, 19], 'an': [11], 'important': [12], 'determinant': [13], 'PCI-related': [15], 'ischemic': [16, 265], 'complications.': [17], 'Cangrelor': [18], 'a': [20, 35, 59, 68, 85], 'potent': [21], 'intravenous': [22], 'adenosine': [23], 'diphosphate': [24], '(ADP)-receptor': [25], 'antagonist': [26], 'that': [27], 'acts': [28], 'rapidly': [29], 'and': [30, 52, 61, 136, 170, 197], 'has': [31], 'quickly': [32], 'reversible': [33], 'effects.In': [34], 'double-blind,': [36], 'placebo-controlled': [37], 'trial,': [38], 'we': [39], 'randomly': [40], 'assigned': [41], '11,145': [42], 'patients': [43, 192], 'who': [44], 'were': [45, 53, 223], 'undergoing': [46], 'either': [47], 'urgent': [48], 'or': [49, 65, 74, 93], 'elective': [50], 'PCI': [51], 'receiving': [54], 'guideline-recommended': [55], 'to': [57, 66, 153, 182, 210, 219, 249], 'receive': [58, 67], 'bolus': [60], 'infusion': [62], 'cangrelor': [64, 134, 168, 195, 236, 246], 'loading': [69], 'dose': [70], '600': [72], 'mg': [73, 76], '300': [75], 'clopidogrel.': [78], 'primary': [80, 113, 126, 160, 251], 'efficacy': [81, 127], 'end': [82, 104, 115, 128, 162, 252], 'point': [83, 105, 116, 129, 163, 253], 'was': [84, 106, 117, 130, 164, 254], 'composite': [86], 'death,': [88], 'myocardial': [89], 'infarction,': [90], 'ischemia-driven': [91], 'revascularization,': [92], 'stent': [94, 107, 268], 'thrombosis': [95, 108, 186], 'at': [96, 109, 120], '48': [97, 110, 121], 'hours': [98], 'after': [99], 'randomization;': [100], 'the': [101, 125, 133, 139, 159, 167, 173, 191, 194, 201, 220, 250, 262, 281], 'key': [102], 'secondary': [103], 'hours.': [111], 'safety': [114, 161], 'severe': [118, 277], 'bleeding': [119], 'hours.The': [122], 'rate': [123, 157, 263], '4.7%': [131], 'in': [132, 138, 166, 172, 188, 193, 198, 200, 225, 276], 'group': [135, 141, 169, 175, 196, 203], '5.9%': [137], 'clopidogrel': [140, 174, 202, 239], '(adjusted': [142], 'odds': [143], 'ratio': [144], 'with': [145, 235, 238, 247, 272], 'cangrelor,': [146], '0.78;': [147], '95%': [148, 179, 207], 'confidence': [149], 'interval': [150], '[CI],': [151], '0.66': [152], '0.93;': [154], 'P=0.005).': [155], '0.16%': [165], '0.11%': [171], '(odds': [176, 204], 'ratio,': [177, 205], '1.50;': [178], 'CI,': [180, 208], '0.53': [181], '4.22;': [183], 'P=0.44).': [184], 'Stent': [185], 'developed': [187], '0.8%': [189], '1.4%': [199], '0.62;': [206], '0.43': [209], '0.90;': [211], 'P=0.01).': [212], 'rates': [214], 'adverse': [216], 'events': [217], 'related': [218], 'study': [221], 'treatment': [222], 'low': [224], 'both': [226], 'groups,': [227], 'though': [228], 'transient': [229], 'dyspnea': [230], 'occurred': [231], 'significantly': [232, 260], 'more': [233], 'frequently': [234], 'than': [237], '(1.2%': [240], 'vs.': [241], '0.3%).': [242], 'benefit': [244], 'from': [245], 'respect': [248], 'consistent': [255], 'across': [256], 'multiple': [257], 'prespecified': [258], 'subgroups.Cangrelor': [259], 'reduced': [261], 'events,': [266], 'including': [267], 'thrombosis,': [269], 'PCI,': [271], 'no': [273], 'significant': [274], 'increase': [275], 'bleeding.': [278], '(Funded': [279], 'by': [280], 'Medicines': [282], 'Company;': [283], 'CHAMPION': [284], 'PHOENIX': [285], 'ClinicalTrials.gov': [286], 'number,': [287], 'NCT01156571.).': [288]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2150655309', 'counts_by_year': [{'year': 2024, 'cited_by_count': 47}, {'year': 2023, 'cited_by_count': 46}, {'year': 2022, 'cited_by_count': 40}, {'year': 2021, 'cited_by_count': 44}, {'year': 2020, 'cited_by_count': 48}, {'year': 2019, 'cited_by_count': 59}, {'year': 2018, 'cited_by_count': 70}, {'year': 2017, 'cited_by_count': 76}, {'year': 2016, 'cited_by_count': 94}, {'year': 2015, 'cited_by_count': 90}, {'year': 2014, 'cited_by_count': 83}, {'year': 2013, 'cited_by_count': 68}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-30T00:07:38.099017', 'created_date': '2016-06-24'}