Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2150226930', 'doi': 'https://doi.org/10.1128/aac.01809-10', 'title': 'Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells', 'display_name': 'Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells', 'publication_year': 2011, 'publication_date': '2011-05-01', 'ids': {'openalex': 'https://openalex.org/W2150226930', 'doi': 'https://doi.org/10.1128/aac.01809-10', 'mag': '2150226930', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21343444', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3088206'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01809-10', 'pdf_url': 'https://aac.asm.org/content/aac/55/5/1961.full.pdf', 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://aac.asm.org/content/aac/55/5/1961.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5003499287', 'display_name': 'Dimitri Topalis', 'orcid': 'https://orcid.org/0000-0002-2640-3671'}, 'institutions': [{'id': 'https://openalex.org/I24156275', 'display_name': 'Rega Institute for Medical Research', 'ror': 'https://ror.org/03w5j8p12', 'country_code': 'BE', 'type': 'facility', 'lineage': ['https://openalex.org/I24156275']}, {'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'D. Topalis', 'raw_affiliation_strings': ['Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium', 'institution_ids': ['https://openalex.org/I24156275', 'https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025580157', 'display_name': 'Ilya Lebeau', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24156275', 'display_name': 'Rega Institute for Medical Research', 'ror': 'https://ror.org/03w5j8p12', 'country_code': 'BE', 'type': 'facility', 'lineage': ['https://openalex.org/I24156275']}, {'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'I. Lebeau', 'raw_affiliation_strings': ['Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium', 'institution_ids': ['https://openalex.org/I24156275', 'https://openalex.org/I99464096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024818475', 'display_name': 'Marcela Krečmerová', 'orcid': 'https://orcid.org/0000-0001-7780-1795'}, 'institutions': [{'id': 'https://openalex.org/I4210145889', 'display_name': 'Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry', 'ror': 'https://ror.org/04nfjn472', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I202391551', 'https://openalex.org/I4210145889']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'M. Krečmerová', 'raw_affiliation_strings': ['Gilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Centre for New Antivirals and Antineoplastics (IOCB), Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Gilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Centre for New Antivirals and Antineoplastics (IOCB), Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic', 'institution_ids': ['https://openalex.org/I4210145889']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030479730', 'display_name': 'Graciela Andreï', 'orcid': 'https://orcid.org/0000-0003-2609-4896'}, 'institutions': [{'id': 'https://openalex.org/I24156275', 'display_name': 'Rega Institute for Medical Research', 'ror': 'https://ror.org/03w5j8p12', 'country_code': 'BE', 'type': 'facility', 'lineage': ['https://openalex.org/I24156275']}, {'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'G. Andrei', 'raw_affiliation_strings': ['Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium', 'institution_ids': ['https://openalex.org/I24156275', 'https://openalex.org/I99464096']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5085228034', 'display_name': 'Robert Snoeck', 'orcid': 'https://orcid.org/0000-0002-7586-5434'}, 'institutions': [{'id': 'https://openalex.org/I24156275', 'display_name': 'Rega Institute for Medical Research', 'ror': 'https://ror.org/03w5j8p12', 'country_code': 'BE', 'type': 'facility', 'lineage': ['https://openalex.org/I24156275']}, {'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': True, 'raw_author_name': 'R. Snoeck', 'raw_affiliation_strings': ['Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium', 'institution_ids': ['https://openalex.org/I24156275', 'https://openalex.org/I99464096']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5085228034'], 'corresponding_institution_ids': ['https://openalex.org/I24156275', 'https://openalex.org/I99464096'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.688, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.845758, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '55', 'issue': '5', 'first_page': '1961', 'last_page': '1967'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11827', 'display_name': 'Polyomavirus-Associated Carcinogenesis and Clinical Manifestations', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11827', 'display_name': 'Polyomavirus-Associated Carcinogenesis and Clinical Manifestations', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12849', 'display_name': 'Parvovirus B19 Infection and Pathogenesis', 'score': 0.9169, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12791', 'display_name': 'Challenges and Opportunities in Full-Duplex Wireless Communication', 'score': 0.9075, 'subfield': {'id': 'https://openalex.org/subfields/2208', 'display_name': 'Electrical and Electronic Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cidofovir', 'display_name': 'Cidofovir', 'score': 0.9736433}, {'id': 'https://openalex.org/keywords/polyomavirus-infections', 'display_name': 'Polyomavirus Infections', 'score': 0.5739128}, {'id': 'https://openalex.org/keywords/phosphonate', 'display_name': 'Phosphonate', 'score': 0.56574416}, {'id': 'https://openalex.org/keywords/viral-nephropathy', 'display_name': 'Viral Nephropathy', 'score': 0.499883}, {'id': 'https://openalex.org/keywords/cytosine', 'display_name': 'Cytosine', 'score': 0.47124487}], 'concepts': [{'id': 'https://openalex.org/C2776824251', 'wikidata': 'https://www.wikidata.org/wiki/Q423445', 'display_name': 'Cidofovir', 'level': 3, 'score': 0.9736433}, {'id': 'https://openalex.org/C2778199330', 'wikidata': 'https://www.wikidata.org/wiki/Q582873', 'display_name': 'BK virus', 'level': 4, 'score': 0.8778373}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.6699737}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.57901734}, {'id': 'https://openalex.org/C2909782663', 'wikidata': 'https://www.wikidata.org/wiki/Q18670504', 'display_name': 'Polyomavirus Infections', 'level': 5, 'score': 0.5739128}, {'id': 'https://openalex.org/C2777626080', 'wikidata': 'https://www.wikidata.org/wiki/Q422733', 'display_name': 'Phosphonate', 'level': 2, 'score': 0.56574416}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53746104}, {'id': 'https://openalex.org/C2776023528', 'wikidata': 'https://www.wikidata.org/wiki/Q178425', 'display_name': 'Cytosine', 'level': 3, 'score': 0.47124487}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.46749532}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.38328102}, {'id': 'https://openalex.org/C2780303639', 'wikidata': 'https://www.wikidata.org/wiki/Q740909', 'display_name': 'Kidney transplantation', 'level': 3, 'score': 0.31673652}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.1270487}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001739', 'descriptor_name': 'BK Virus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D009705', 'descriptor_name': 'Nucleosides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D063065', 'descriptor_name': 'Organophosphonates', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D001739', 'descriptor_name': 'BK Virus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D000077404', 'descriptor_name': 'Cidofovir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003561', 'descriptor_name': 'Cytarabine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003561', 'descriptor_name': 'Cytarabine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003596', 'descriptor_name': 'Cytosine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003596', 'descriptor_name': 'Cytosine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': False}, {'descriptor_ui': 'D003596', 'descriptor_name': 'Cytosine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007555', 'descriptor_name': 'Isoxazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007555', 'descriptor_name': 'Isoxazoles', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D000077339', 'descriptor_name': 'Leflunomide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009705', 'descriptor_name': 'Nucleosides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D063065', 'descriptor_name': 'Organophosphonates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014740', 'descriptor_name': 'Vidarabine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014740', 'descriptor_name': 'Vidarabine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01809-10', 'pdf_url': 'https://aac.asm.org/content/aac/55/5/1961.full.pdf', 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3088206', 'pdf_url': 'https://europepmc.org/articles/pmc3088206?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088206', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21343444', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.01809-10', 'pdf_url': 'https://aac.asm.org/content/aac/55/5/1961.full.pdf', 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.82, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1599295812', 'https://openalex.org/W1743283402', 'https://openalex.org/W1969536860', 'https://openalex.org/W1989408309', 'https://openalex.org/W1994960623', 'https://openalex.org/W1997204666', 'https://openalex.org/W2000379621', 'https://openalex.org/W2002700895', 'https://openalex.org/W2009992204', 'https://openalex.org/W2011096245', 'https://openalex.org/W2012567881', 'https://openalex.org/W2015970664', 'https://openalex.org/W2032465802', 'https://openalex.org/W2033949362', 'https://openalex.org/W2047248494', 'https://openalex.org/W2048541780', 'https://openalex.org/W2067222383', 'https://openalex.org/W2071073000', 'https://openalex.org/W2085030852', 'https://openalex.org/W2085487956', 'https://openalex.org/W2088168913', 'https://openalex.org/W2088530937', 'https://openalex.org/W2097904456', 'https://openalex.org/W2098871385', 'https://openalex.org/W2102565837', 'https://openalex.org/W2107610513', 'https://openalex.org/W2116016714', 'https://openalex.org/W2116375742', 'https://openalex.org/W2119749824', 'https://openalex.org/W2122060603', 'https://openalex.org/W2122403434', 'https://openalex.org/W2136143258', 'https://openalex.org/W2139759293', 'https://openalex.org/W2140463009', 'https://openalex.org/W2147145007', 'https://openalex.org/W2147930927', 'https://openalex.org/W2148284922', 'https://openalex.org/W2154801452', 'https://openalex.org/W2155620154', 'https://openalex.org/W2160994473', 'https://openalex.org/W2169726349', 'https://openalex.org/W2224780480', 'https://openalex.org/W2256756668', 'https://openalex.org/W2301716535', 'https://openalex.org/W2316912275', 'https://openalex.org/W2372039679', 'https://openalex.org/W318219195', 'https://openalex.org/W3217730596', 'https://openalex.org/W93885486'], 'related_works': ['https://openalex.org/W4298177886', 'https://openalex.org/W2953944003', 'https://openalex.org/W2414055449', 'https://openalex.org/W2337912353', 'https://openalex.org/W2205973852', 'https://openalex.org/W2150226930', 'https://openalex.org/W2132342887', 'https://openalex.org/W2067721689', 'https://openalex.org/W2033769541', 'https://openalex.org/W1977007881'], 'abstract_inverted_index': {'ABSTRACT': [0], 'BK': [1], 'virus': [2, 5, 16, 80], '(BKV),': [3], 'a': [4, 12, 74, 96], 'belonging': [6], 'to': [7, 189], 'the': [8, 45, 106, 164, 172, 181], 'polyomavirus': [9], 'family,': [10], 'is': [11, 186], 'circular': [13], 'double-stranded': [14], 'DNA': [15, 79], 'that': [17, 144], 'causes': [18], 'nephropathies': [19], 'in': [20, 34, 122], 'immunocompromised': [21], 'patients': [22, 37], 'after': [23], 'kidney': [24, 35], 'or': [25], 'bone': [26], 'marrow': [27], 'transplantation.': [28], 'The': [29, 85, 141], 'occurrence': [30], 'of': [31, 47, 57, 71, 87, 99, 108, 112, 168, 183], 'polyomavirus-associated': [32], 'nephropathy': [33, 59], 'transplant': [36], 'may': [38], 'trigger': [39], 'graft': [40], 'loss,': [41], 'and': [42, 134, 147, 160], 'guidelines': [43], 'for': [44, 116, 180], 'management': [46, 182], 'BKV': [48, 58, 120, 169, 191], 'infection': [49], 'have': [50], 'not': [51, 187], 'yet': [52], 'been': [53, 83, 92, 178], 'clearly': [54], 'established.': [55], 'Treatment': [56], 'with': [60, 73, 95], 'cidofovir': [61], '(CDV)': [62], '{(': [63], 'S': [64, 152], ')-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine': [65], '(HPMPC)},': [66], 'an': [67], 'acyclic': [68, 113], 'phosphonate': [69], 'analogue': [70], 'dCMP': [72], 'broad': [75], 'antiviral': [76], 'activity': [77], 'against': [78, 119], 'infections,': [81], 'has': [82, 91, 176], 'proposed.': [84], 'benefit': [86], 'this': [88, 102], 'small-molecule-based': [89], 'treatment': [90], 'evaluated': [93], 'only': [94], 'limited': [97], 'number': [98], 'cases.': [100], 'In': [101], 'study,': [103], 'we': [104], 'report': [105], 'evaluation': [107], 'three': [109], 'different': [110, 124], 'classes': [111], 'nucleoside': [114], 'phosphonates': [115], 'their': [117], 'activities': [118], 'replication': [121, 192], 'two': [123], 'primary': [125], 'renal': [126, 128, 136], 'cells:': [127], 'proximal': [129], 'tubular': [130], 'epithelial': [131, 138], 'cells': [132], '(RPTECs)': [133], 'human': [135], 'cortical': [137], '(HRCE)': [139], 'cells.': [140], 'data': [142], 'indicate': [143], 'besides': [145], 'HPMPC': [146], 'its': [148], 'cyclic': [149, 155], 'form,': [150], '(': [151], ')-1-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine': [153], '(HPMP-5-azaC),': [154], 'HPMP': [156], '(cHPMP)-5-azaC,': [157], 'hexadecyloxyethyl': [158], '(HDE)-cHPMP-5-azaC,': [159], '9-[2-(phosphonomethoxy)ethyl]guanine': [161], '(PMEG)': [162], 'are': [163], 'most': [165], 'selective': [166], 'inhibitors': [167], 'replication.': [170], 'On': [171], 'contrary,': [173], 'leflunomide,': [174], 'which': [175], 'also': [177], 'proposed': [179], 'BKV-associated': [184], 'diseases,': [185], 'able': [188], 'inhibit': [190], 'at': [193], 'nontoxic': [194], 'concentrations.': [195]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2150226930', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-09-13T10:54:49.063886', 'created_date': '2016-06-24'}