Title: Transmembrane Transport of Chloride and Iodide in Proximal Rat Tubules
Abstract: Abstract The transport mechanism for chloride across the proximal tubular epithelia in the rat was investigated with a free‐flow micropuncture technique. The purpose of the investigation was to determine whether there is an active carrier system for chloride transport out of the tubule with different affinities for different halides and higher for iodide than for chloride. The TF/P values for sodium, potassium, chloride and iodide were determined simultaneously. The TF/P value for chloride (1.15) was significantly lower than the TF/P value for iodide (1.73). It was concluded that there is no evidence of an active transport system and that chloride and iodide are transported passively out of the tubular lumen, the permeability for iodide being somewhat lower than for chloride.
Publication Year: 1970
Publication Date: 1970-03-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 11
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