Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2149881769', 'doi': 'https://doi.org/10.1093/mutage/16.3.203', 'title': 'Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection', 'display_name': 'Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection', 'publication_year': 2001, 'publication_date': '2001-05-01', 'ids': {'openalex': 'https://openalex.org/W2149881769', 'doi': 'https://doi.org/10.1093/mutage/16.3.203', 'mag': '2149881769', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11320144'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/mutage/16.3.203', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S101337917', 'display_name': 'Mutagenesis', 'issn_l': '0267-8357', 'issn': ['0267-8357', '1464-3804'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://dspace.unitus.it/bitstream/2067/1707/3/Mutagenesis1707.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109325386', 'display_name': 'G Gualandi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I138938424', 'display_name': 'Università degli Studi della Tuscia', 'ror': 'https://ror.org/03svwq685', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I138938424']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'G Gualandi', 'raw_affiliation_strings': ['DABAC, Università degli Studi della Tuscia, via SC deLellis snc, 01100 Viterbo, Italy. [email protected]'], 'affiliations': [{'raw_affiliation_string': 'DABAC, Università degli Studi della Tuscia, via SC deLellis snc, 01100 Viterbo, Italy. [email protected]', 'institution_ids': ['https://openalex.org/I138938424']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5096784626', 'display_name': 'L Giselico', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'L Giselico', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005709282', 'display_name': 'M. Carloni', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Carloni', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057955297', 'display_name': 'F. Palitti', 'orcid': 'https://orcid.org/0000-0001-9644-1553'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'F Palitti', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067224966', 'display_name': 'Pasquale Mosesso', 'orcid': 'https://orcid.org/0000-0001-5648-1366'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'P Mosesso', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110002398', 'display_name': 'A M Alfonsi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A M Alfonsi', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2895, 'currency': 'GBP', 'value_usd': 3551, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.719, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.751973, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '16', 'issue': '3', 'first_page': '203', 'last_page': '208'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10685', 'display_name': 'Viral-associated cancers and disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10685', 'display_name': 'Viral-associated cancers and disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11827', 'display_name': 'Polyomavirus and related diseases', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chromosome-instability', 'display_name': 'Chromosome instability', 'score': 0.6641105}, {'id': 'https://openalex.org/keywords/clone', 'display_name': 'clone (Java method)', 'score': 0.53194004}], 'concepts': [{'id': 'https://openalex.org/C178169997', 'wikidata': 'https://www.wikidata.org/wiki/Q2892636', 'display_name': 'Genome instability', 'level': 4, 'score': 0.7352232}, {'id': 'https://openalex.org/C2781375147', 'wikidata': 'https://www.wikidata.org/wiki/Q6900', 'display_name': 'Epstein–Barr virus', 'level': 3, 'score': 0.70002496}, {'id': 'https://openalex.org/C140752955', 'wikidata': 'https://www.wikidata.org/wiki/Q1087752', 'display_name': 'Chromosome instability', 'level': 4, 'score': 0.6641105}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.6419091}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.63356197}, {'id': 'https://openalex.org/C81089528', 'wikidata': 'https://www.wikidata.org/wiki/Q5134986', 'display_name': 'clone (Java method)', 'level': 3, 'score': 0.53194004}, {'id': 'https://openalex.org/C36681516', 'wikidata': 'https://www.wikidata.org/wiki/Q1700733', 'display_name': 'Micronucleus', 'level': 4, 'score': 0.48745346}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.47610673}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.43457237}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.41220453}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.38603178}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.36170578}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.35403386}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.3488232}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.22297299}, {'id': 'https://openalex.org/C45080847', 'wikidata': 'https://www.wikidata.org/wiki/Q1658004', 'display_name': 'Micronucleus test', 'level': 3, 'score': 0.21599102}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.20583397}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.17847466}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.09284201}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': True}, {'descriptor_ui': 'D004854', 'descriptor_name': 'Herpesvirus 4, Human', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007239', 'descriptor_name': 'Infections', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015139', 'descriptor_name': 'Blotting, Southern', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003703', 'descriptor_name': 'Demecolcine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003703', 'descriptor_name': 'Demecolcine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005978', 'descriptor_name': 'Glutathione', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005978', 'descriptor_name': 'Glutathione', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004854', 'descriptor_name': 'Herpesvirus 4, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006861', 'descriptor_name': 'Hydrogen Peroxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006861', 'descriptor_name': 'Hydrogen Peroxide', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D017403', 'descriptor_name': 'In Situ Hybridization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007239', 'descriptor_name': 'Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015162', 'descriptor_name': 'Micronucleus Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010545', 'descriptor_name': 'Peroxides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010545', 'descriptor_name': 'Peroxides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/mutage/16.3.203', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S101337917', 'display_name': 'Mutagenesis', 'issn_l': '0267-8357', 'issn': ['0267-8357', '1464-3804'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/2067/1707', 'pdf_url': 'https://dspace.unitus.it/bitstream/2067/1707/3/Mutagenesis1707.pdf', 'source': {'id': 'https://openalex.org/S4377196492', 'display_name': 'UnitusOpen (Tuscia University)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I138938424', 'host_organization_name': 'Università degli Studi della Tuscia', 'host_organization_lineage': ['https://openalex.org/I138938424'], 'host_organization_lineage_names': ['Università degli Studi della Tuscia'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11320144', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/2067/1707', 'pdf_url': 'https://dspace.unitus.it/bitstream/2067/1707/3/Mutagenesis1707.pdf', 'source': {'id': 'https://openalex.org/S4377196492', 'display_name': 'UnitusOpen (Tuscia University)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I138938424', 'host_organization_name': 'Università degli Studi della Tuscia', 'host_organization_lineage': ['https://openalex.org/I138938424'], 'host_organization_lineage_names': ['Università degli Studi della Tuscia'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'score': 0.46, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W1481866568', 'https://openalex.org/W1498444782', 'https://openalex.org/W1537962128', 'https://openalex.org/W1575369917', 'https://openalex.org/W1853273344', 'https://openalex.org/W1931862903', 'https://openalex.org/W196344020', 'https://openalex.org/W1982133573', 'https://openalex.org/W2002586916', 'https://openalex.org/W2005111695', 'https://openalex.org/W2023191154', 'https://openalex.org/W2035426881', 'https://openalex.org/W2044316949', 'https://openalex.org/W2050782389', 'https://openalex.org/W2055207902', 'https://openalex.org/W2056204961', 'https://openalex.org/W2061290039', 'https://openalex.org/W2061481377', 'https://openalex.org/W2080482903', 'https://openalex.org/W2082232487', 'https://openalex.org/W2083316920', 'https://openalex.org/W2085505131', 'https://openalex.org/W2094799975', 'https://openalex.org/W2123628489', 'https://openalex.org/W2127279305', 'https://openalex.org/W2138713591', 'https://openalex.org/W2139700920', 'https://openalex.org/W2323697765', 'https://openalex.org/W2415017487'], 'related_works': ['https://openalex.org/W2357952934', 'https://openalex.org/W2352719856', 'https://openalex.org/W2152859477', 'https://openalex.org/W2134683317', 'https://openalex.org/W2084475506', 'https://openalex.org/W2073596489', 'https://openalex.org/W2048694704', 'https://openalex.org/W1995981964', 'https://openalex.org/W1506578365', 'https://openalex.org/W1140116790'], 'abstract_inverted_index': {'The': [0, 65], 'level': [1, 83], 'of': [2, 22, 57, 62, 84, 108, 149, 154], 'genetic': [3, 137, 155], 'instability,': [4, 156], 'as': [5, 43, 122], 'assessed': [6], 'by': [7, 40, 45, 69, 93], 'micronucleus': [8], '(MN)': [9], 'formation,': [10], 'was': [11, 67, 79], 'higher': [12, 81], 'in': [13, 27, 31, 46, 86, 111, 126, 151], 'Epstein–Barr': [14], 'virus': [15], '(EBV)-converted': [16], 'B-cell': [17], 'lines': [18], 'with': [19, 71, 136], 'one': [20], 'copy': [21], 'the': [23, 32, 55, 60, 106, 127, 143, 152], 'EBV': [24, 41, 58, 129, 150], 'genome': [25], 'integrated': [26], 'each': [28], 'cell': [29], 'than': [30], 'parental,': [33], 'EBV-negative,': [34], 'B': [35], 'lymphoma': [36], 'cells.': [37, 88], 'MN': [38, 109], 'induced': [39], 'latency,': [42], 'analysed': [44], 'situ': [47], 'hybridization,': [48], 'contained': [49], 'mainly': [50], 'centromeric': [51], 'regions,': [52], 'indicating': [53], 'that': [54, 77, 125, 158], 'presence': [56], 'affects': [59], 'segregation': [61], 'entire': [63], 'chromosomes.': [64], 'instability': [66], 'inhibited': [68], 'treatment': [70], 'antioxidants.': [72], 'Flow': [73], 'cytometric': [74], 'analysis': [75], 'indicated': [76], 'there': [78], 'a': [80, 146], 'basal': [82], 'peroxides': [85], 'EBV+': [87], 'Direct': [89], 'oxidative': [90], 'stress': [91], 'caused': [92], 'hydrogen': [94], 'peroxide': [95], '(which': [96], 'is': [97], 'known': [98], 'to': [99, 120, 162], 'be': [100], 'both': [101], 'apoptogenic': [102], 'and': [103], 'mutagenic)': [104], 'enhanced': [105], 'number': [107], 'only': [110], 'an': [112], 'EBV-converted': [113], 'clone.': [114], 'These': [115, 139], 'cells': [116, 130, 135], 'were': [117], 'also': [118], 'resistant': [119], 'apoptosis,': [121], 'expected,': [123], 'suggesting': [124, 157], 'parental': [128], 'apoptosis': [131], 'may': [132], 'efficiently': [133], 'eliminate': [134], 'damage.': [138], 'results': [140], 'show': [141], 'for': [142], 'first': [144], 'time': [145], 'direct': [147], 'involvement': [148], 'induction': [153], 'it': [159], 'could': [160], 'contribute': [161], 'tumour': [163], 'progression.': [164]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2149881769', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-10T05:59:14.561310', 'created_date': '2016-06-24'}