Title: Complete androgen insensitivity syndrome in three sisters: A case report
Abstract: Complete androgen insensitivity syndrome (CAIS) (testicular feminization) is the most common cause of malepseudohermaphroditism.The underlying main pathology is an end organ resistance to androgen stimulation, and as a result, this impairs the differentiation of the body structures and systems which this hormone affects.Inheritance of this disorder is by means of an X-linked recessive gene that is responsible for the intracellular androgen receptors.CAIS may be observed in several members of a family.For this reason, the family members of the affected individual should be screened.In this article we present a case of three sisters diagnosed with CAIS after investigating the pedigree of one of them owing to an inguinal mass and diagnosing with CAIS.