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'Mutations': [77], 'in': [78, 92, 95, 166], 'this': [79], 'disrupt': [81], 'association': [83, 118, 133], 'with': [86, 100, 121, 152], 'E-': [88], 'or': [89, 183, 188], 'A-cdk2': [91], 'vitro': [93], 'vivo': [96], 'selectively': [98], 'interfere': [99], 'dephosphorylation': [102, 126, 136], 'A': [106], 'peptide': [107], 'based': [108], 'on': [109], 'p21': [114, 130], 'competitively': [115], 'disrupts': [116], 'cyclin-cdks': [122], 'inhibits': [124, 131], 'kinase.': [129], 'Cdc25A-cyclin-cdk2': [132], 'cdk2.': [138], 'Conversely,': [139], 'which': [141, 180], 'itself': [143], 'an': [144], 'oncogene': [145], 'up-regulated': [146], 'Myc': [149], 'oncogene,': [150], 'cyclin-cdk': [153], 'protects': [155, 163], 'it': [156], 'inhibition': [158, 171], 'p21.': [160, 173], 'also': [162], 'DNA': [164], 'replication': [165], 'Xenopus': [167], 'egg': [168], 'extracts': [169], 'These': [174], 'results': [175], 'describe': [176], 'mechanism': [178], 'Myc-': [182], 'Cdc25A-induced': [184], 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