Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2149087782', 'doi': 'https://doi.org/10.1096/fj.01-0673fje', 'title': 'Simulated microgravity alters differentiation and increases apoptosis in human follicular thyroid carcinoma cells', 'display_name': 'Simulated microgravity alters differentiation and increases apoptosis in human follicular thyroid carcinoma cells', 'publication_year': 2002, 'publication_date': '2002-02-25', 'ids': {'openalex': 'https://openalex.org/W2149087782', 'doi': 'https://doi.org/10.1096/fj.01-0673fje', 'mag': '2149087782', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11919168'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1096/fj.01-0673fje', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S25293849', 'display_name': 'The FASEB Journal', 'issn_l': '0892-6638', 'issn': ['0892-6638', '1530-6860'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5082120013', 'display_name': 'Daniela Grimm', 'orcid': 'https://orcid.org/0000-0002-4991-3105'}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Daniela Grimm', 'raw_affiliation_strings': ['Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010781386', 'display_name': 'Johann Bauer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150093', 'display_name': 'Max Planck Institute of Biochemistry', 'ror': 'https://ror.org/04py35477', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210150093']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Johann Bauer', 'raw_affiliation_strings': ['Max-Planck Institute of Biochemistry Martinsried Germany'], 'affiliations': [{'raw_affiliation_string': 'Max-Planck Institute of Biochemistry Martinsried Germany', 'institution_ids': ['https://openalex.org/I4210150093']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091386136', 'display_name': 'Peter Koßmehl', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Peter Kossmehl', 'raw_affiliation_strings': ['Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038295064', 'display_name': 'Mehdi Shakibaei', 'orcid': 'https://orcid.org/0000-0002-6304-7506'}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Mehdi Shakibaei', 'raw_affiliation_strings': ['Institute of AnatomyFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of AnatomyFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108385436', 'display_name': 'Johann Schönberger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I60668342', 'display_name': 'University of Regensburg', 'ror': 'https://ror.org/01eezs655', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I60668342']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Johann Schönberger', 'raw_affiliation_strings': ['Department of Nuclear MedicineUniversity of Regensburg Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Nuclear MedicineUniversity of Regensburg Germany', 'institution_ids': ['https://openalex.org/I60668342']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056478769', 'display_name': 'Holger Pickenhahn', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Holger Pickenhahn', 'raw_affiliation_strings': ['Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035973444', 'display_name': 'Gundula Schulze‐Tanzil', 'orcid': 'https://orcid.org/0000-0002-9807-9532'}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Gundula Schulze-Tanzil', 'raw_affiliation_strings': ['Institute of AnatomyFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of AnatomyFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000750109', 'display_name': 'Roland Vetter', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Roland Vetter', 'raw_affiliation_strings': ['Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111711364', 'display_name': 'Christoph Eilles', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I60668342', 'display_name': 'University of Regensburg', 'ror': 'https://ror.org/01eezs655', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I60668342']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Christoph Eilles', 'raw_affiliation_strings': ['Department of Nuclear MedicineUniversity of Regensburg Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Nuclear MedicineUniversity of Regensburg Germany', 'institution_ids': ['https://openalex.org/I60668342']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103493918', 'display_name': 'Martin Paul', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I75951250', 'display_name': 'Freie Universität Berlin', 'ror': 'https://ror.org/046ak2485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I75951250']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Martin Paul', 'raw_affiliation_strings': ['Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Pharmacology and ToxicologyBenjamin Franklin Medical CenterFreie Universität Berlin Germany', 'institution_ids': ['https://openalex.org/I75951250']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5032136007', 'display_name': 'Augusto Cogoli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I35440088', 'display_name': 'ETH Zurich', 'ror': 'https://ror.org/05a28rw58', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I2799323385', 'https://openalex.org/I35440088']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Augusto Cogoli', 'raw_affiliation_strings': ['Space Biology Group ETH Zurich Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Space Biology Group ETH Zurich Switzerland', 'institution_ids': ['https://openalex.org/I35440088']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.515, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 163, 'citation_normalized_percentile': {'value': 0.999912, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '16', 'issue': '6', 'first_page': '604', 'last_page': '606'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12005', 'display_name': 'Spaceflight effects on biology', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12005', 'display_name': 'Spaceflight effects on biology', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11968', 'display_name': 'High Altitude and Hypoxia', 'score': 0.9448, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10676', 'display_name': 'Genetics, Aging, and Longevity in Model Organisms', 'score': 0.9243, 'subfield': {'id': 'https://openalex.org/subfields/1302', 'display_name': 'Aging'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dna-laddering', 'display_name': 'DNA laddering', 'score': 0.53178835}, {'id': 'https://openalex.org/keywords/clinostat', 'display_name': 'Clinostat', 'score': 0.5023408}], 'concepts': [{'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.6957371}, {'id': 'https://openalex.org/C189165786', 'wikidata': 'https://www.wikidata.org/wiki/Q193825', 'display_name': 'Extracellular matrix', 'level': 2, 'score': 0.6090354}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6037913}, {'id': 'https://openalex.org/C155878803', 'wikidata': 'https://www.wikidata.org/wiki/Q5205755', 'display_name': 'DNA laddering', 'level': 5, 'score': 0.53178835}, {'id': 'https://openalex.org/C86492073', 'wikidata': 'https://www.wikidata.org/wiki/Q413766', 'display_name': 'Fibronectin', 'level': 3, 'score': 0.52678996}, {'id': 'https://openalex.org/C2777393558', 'wikidata': 'https://www.wikidata.org/wiki/Q2979318', 'display_name': 'Clinostat', 'level': 2, 'score': 0.5023408}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4741154}, {'id': 'https://openalex.org/C2779814568', 'wikidata': 'https://www.wikidata.org/wiki/Q58345', 'display_name': 'Laminin', 'level': 3, 'score': 0.44806895}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.36220682}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.26397723}, {'id': 'https://openalex.org/C43759708', 'wikidata': 'https://www.wikidata.org/wiki/Q3749256', 'display_name': 'DNA fragmentation', 'level': 4, 'score': 0.2603199}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17602691}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.16285804}], 'mesh': [{'descriptor_ui': 'D018263', 'descriptor_name': 'Adenocarcinoma, Follicular', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013964', 'descriptor_name': 'Thyroid Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D018263', 'descriptor_name': 'Adenocarcinoma, Follicular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018263', 'descriptor_name': 'Adenocarcinoma, Follicular', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018263', 'descriptor_name': 'Adenocarcinoma, Follicular', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015815', 'descriptor_name': 'Cell Adhesion Molecules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015815', 'descriptor_name': 'Cell Adhesion Molecules', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016326', 'descriptor_name': 'Extracellular Matrix Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016326', 'descriptor_name': 'Extracellular Matrix Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008856', 'descriptor_name': 'Microscopy, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013963', 'descriptor_name': 'Thyroid Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013963', 'descriptor_name': 'Thyroid Hormones', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D013964', 'descriptor_name': 'Thyroid Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013964', 'descriptor_name': 'Thyroid Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013964', 'descriptor_name': 'Thyroid Neoplasms', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018474', 'descriptor_name': 'Weightlessness Simulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1096/fj.01-0673fje', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S25293849', 'display_name': 'The FASEB Journal', 'issn_l': '0892-6638', 'issn': ['0892-6638', '1530-6860'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11919168', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.46, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W1482244736', 'https://openalex.org/W1483611897', 'https://openalex.org/W1500535013', 'https://openalex.org/W1527442973', 'https://openalex.org/W1549821546', 'https://openalex.org/W1567256313', 'https://openalex.org/W1573076173', 'https://openalex.org/W1589415602', 'https://openalex.org/W1642592182', 'https://openalex.org/W1775644376', 'https://openalex.org/W1945782775', 'https://openalex.org/W1966054230', 'https://openalex.org/W1966167849', 'https://openalex.org/W1966997945', 'https://openalex.org/W1968189869', 'https://openalex.org/W1976044858', 'https://openalex.org/W1982372868', 'https://openalex.org/W1984161467', 'https://openalex.org/W1993191394', 'https://openalex.org/W1996120672', 'https://openalex.org/W2000091732', 'https://openalex.org/W2004617066', 'https://openalex.org/W2013714354', 'https://openalex.org/W2015139117', 'https://openalex.org/W2016198585', 'https://openalex.org/W2023040267', 'https://openalex.org/W2041382001', 'https://openalex.org/W2059193195', 'https://openalex.org/W2059457961', 'https://openalex.org/W2063111266', 'https://openalex.org/W2067203621', 'https://openalex.org/W2069169998', 'https://openalex.org/W2072067396', 'https://openalex.org/W2075469819', 'https://openalex.org/W2075616620', 'https://openalex.org/W2078297328', 'https://openalex.org/W2084725182', 'https://openalex.org/W2091901317', 'https://openalex.org/W2095857644', 'https://openalex.org/W2098301610', 'https://openalex.org/W2113597032', 'https://openalex.org/W2119859866', 'https://openalex.org/W2128016549', 'https://openalex.org/W2238908191', 'https://openalex.org/W2240983374', 'https://openalex.org/W2313477083', 'https://openalex.org/W2406668866', 'https://openalex.org/W2467546421', 'https://openalex.org/W37292645', 'https://openalex.org/W37847007', 'https://openalex.org/W4247775902', 'https://openalex.org/W573800856', 'https://openalex.org/W618617910'], 'related_works': ['https://openalex.org/W3048316964', 'https://openalex.org/W2481695001', 'https://openalex.org/W2186782318', 'https://openalex.org/W2128518557', 'https://openalex.org/W2115780596', 'https://openalex.org/W2106761248', 'https://openalex.org/W2064487804', 'https://openalex.org/W2034939167', 'https://openalex.org/W1995698795', 'https://openalex.org/W1971460289'], 'abstract_inverted_index': {'This': [0], 'study': [1], 'focuses': [2], 'on': [3, 10, 20, 83], 'the': [4, 11, 42, 52, 59, 84, 90, 178, 195], 'effects': [5], 'of': [6, 40, 61, 89, 94, 97, 103, 108, 197, 204], 'simulated': [7, 205], 'microgravity': [8], '(0g)': [9], 'human': [12], 'follicular': [13, 164], 'thyroid': [14, 165, 184], 'carcinoma': [15], 'cell': [16, 152], 'line': [17], 'ML-1.': [18], 'Cultured': [19], 'a': [21, 174, 202], 'three-dimensional': [22, 27], 'clinostat,': [23], 'ML-1': [24, 80], 'cells': [25, 43, 81], 'formed': [26], 'MCTSs': [28], '(MCTS': [29], 'diameter:': [30], '0.3': [31], '+/-': [32], '0.01': [33], 'mm).': [34], 'After': [35], '24': [36], 'and': [37, 47, 64, 70, 96, 128, 142, 155, 159], '48': [38], 'h': [39], 'clinorotation,': [41], 'significantly': [44], 'decreased': [45], 'fT3': [46], 'fT4': [48], 'secretion': [49], 'but': [50, 99], 'up-regulated': [51], 'thyroid-stimulating': [53], 'hormone-receptor': [54], 'expression': [55], 'as': [56, 58, 112, 201], 'well': [57], 'production': [60], 'vimentin,': [62], 'vinculin,': [63], 'extracellular': [65, 156], 'matrix': [66, 157], 'proteins': [67, 158], '(collagen': [68], 'I': [69], 'III,': [71], 'laminin,': [72], 'fibronectin,': [73], 'chondroitin': [74], 'sulfate)': [75], 'compared': [76], 'with': [77], 'controls.': [78], 'Furthermore,': [79], 'grown': [82], 'clinostat': [85], 'showed': [86, 100], 'elevated': [87], 'amounts': [88], 'apoptosis-associated': [91], 'Fas': [92], 'protein,': [93], 'p53,': [95], 'bax': [98], 'reduced': [101], 'quantities': [102], 'bcl-2.': [104], 'In': [105, 168], 'addition,': [106], 'signs': [107], 'apoptosis': [109, 162, 198], 'became': [110], 'detectable,': [111], 'assessed': [113], 'by': [114, 194], 'terminal': [115], 'deoxynucleotidyl': [116], 'transferase-mediated': [117], 'dUTP': [118], 'digoxigenin': [119], 'nick': [120], 'end': [121], 'labeling,': [122], "4',": [123], '6-diamidino-2-phenylindole': [124], 'staining,': [125], 'DNA': [126], 'laddering,': [127], '85-kDa': [129], 'apoptosis-related': [130], 'cleavage': [131], 'fragments.': [132], 'These': [133, 144], 'fragments': [134], 'resulted': [135], 'from': [136], 'enhanced': [137], '116-kDa': [138], 'poly(ADP-ribose)polymerase': [139], '(PARP)': [140], 'activity': [141], 'apoptosis.': [143], 'observations': [145], 'suggest': [146], 'that': [147, 180], 'clinorotation': [148], 'elevates': [149], 'intermediate': [150], 'filaments,': [151], 'adhesion': [153], 'molecules,': [154], 'simultaneously': [160], 'induces': [161], 'in': [163, 199], 'cancer': [166], 'cells.': [167], 'conclusion,': [169], 'our': [170], 'experiments': [171], 'could': [172], 'provide': [173], 'regulatory': [175], 'basis': [176], 'for': [177], 'finding': [179], 'astronauts': [181], 'show': [182], 'low': [183], 'hormone': [185], 'levels': [186], 'after': [187], 'space': [188], 'flight,': [189], 'which': [190], 'may': [191], 'be': [192], 'explained': [193], 'increase': [196], 'thyrocytes': [200], 'result': [203], '0g.': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2149087782', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 12}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 11}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 11}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-26T11:33:34.169466', 'created_date': '2016-06-24'}