Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2148842621', 'doi': 'https://doi.org/10.1101/sqb.2006.71.013', 'title': 'MicroRNAs Silence Gene Expression by Repressing Protein Expression and/or by Promoting mRNA Decay', 'display_name': 'MicroRNAs Silence Gene Expression by Repressing Protein Expression and/or by Promoting mRNA Decay', 'publication_year': 2006, 'publication_date': '2006-01-01', 'ids': {'openalex': 'https://openalex.org/W2148842621', 'doi': 'https://doi.org/10.1101/sqb.2006.71.013', 'mag': '2148842621', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17381335'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/sqb.2006.71.013', 'pdf_url': 'http://symposium.cshlp.org/content/71/523.full.pdf', 'source': {'id': 'https://openalex.org/S78756772', 'display_name': 'Cold Spring Harbor Symposia on Quantitative Biology', 'issn_l': '0091-7451', 'issn': ['0091-7451', '1943-4456'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://symposium.cshlp.org/content/71/523.full.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5010075122', 'display_name': 'Isabelle Behm‐Ansmant', 'orcid': 'https://orcid.org/0000-0001-8909-0660'}, 'institutions': [{'id': 'https://openalex.org/I4210112458', 'display_name': 'Max Planck Institute for Developmental Biology', 'ror': 'https://ror.org/022jc0g24', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210112458']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'I. BEHM-ANSMANT', 'raw_affiliation_strings': ['MPI for Developmental Biology, D-72076 Tuebingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'MPI for Developmental Biology, D-72076 Tuebingen, Germany', 'institution_ids': ['https://openalex.org/I4210112458']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078937992', 'display_name': 'Jan Rehwinkel', 'orcid': 'https://orcid.org/0000-0003-3841-835X'}, 'institutions': [{'id': 'https://openalex.org/I4210112458', 'display_name': 'Max Planck Institute for Developmental Biology', 'ror': 'https://ror.org/022jc0g24', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210112458']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'J. REHWINKEL', 'raw_affiliation_strings': ['MPI for Developmental Biology, D-72076 Tuebingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'MPI for Developmental Biology, D-72076 Tuebingen, Germany', 'institution_ids': ['https://openalex.org/I4210112458']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5034397495', 'display_name': 'Elisa Izaurralde', 'orcid': 'https://orcid.org/0000-0001-7365-2649'}, 'institutions': [{'id': 'https://openalex.org/I4210112458', 'display_name': 'Max Planck Institute for Developmental Biology', 'ror': 'https://ror.org/022jc0g24', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210112458']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'E. IZAURRALDE', 'raw_affiliation_strings': ['MPI for Developmental Biology, D-72076 Tuebingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'MPI for Developmental Biology, D-72076 Tuebingen, Germany', 'institution_ids': ['https://openalex.org/I4210112458']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.469, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 247, 'citation_normalized_percentile': {'value': 0.77976, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '71', 'issue': '0', 'first_page': '523', 'last_page': '530'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA Regulation in Cancer and Development', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA Methylation and Modification in Gene Expression', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/p-bodies', 'display_name': 'P-bodies', 'score': 0.75443685}, {'id': 'https://openalex.org/keywords/argonaute', 'display_name': 'Argonaute', 'score': 0.74085605}, {'id': 'https://openalex.org/keywords/gene-expression-regulation', 'display_name': 'Gene Expression Regulation', 'score': 0.588709}, {'id': 'https://openalex.org/keywords/mrna-modification', 'display_name': 'mRNA modification', 'score': 0.571188}, {'id': 'https://openalex.org/keywords/mrna-decay', 'display_name': 'mRNA Decay', 'score': 0.564822}, {'id': 'https://openalex.org/keywords/micrornas', 'display_name': 'MicroRNAs', 'score': 0.520678}, {'id': 'https://openalex.org/keywords/gene-expression', 'display_name': 'Gene Expression', 'score': 0.512514}, {'id': 'https://openalex.org/keywords/nonsense-mediated-decay', 'display_name': 'Nonsense-mediated decay', 'score': 0.49049824}], 'concepts': [{'id': 'https://openalex.org/C162419368', 'wikidata': 'https://www.wikidata.org/wiki/Q14864908', 'display_name': 'P-bodies', 'level': 5, 'score': 0.75443685}, {'id': 'https://openalex.org/C201853390', 'wikidata': 'https://www.wikidata.org/wiki/Q413236', 'display_name': 'Argonaute', 'level': 5, 'score': 0.74085605}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.6948774}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6669496}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.60363317}, {'id': 'https://openalex.org/C149364088', 'wikidata': 'https://www.wikidata.org/wiki/Q185917', 'display_name': 'Translation (biology)', 'level': 4, 'score': 0.5752581}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.55476797}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5306125}, {'id': 'https://openalex.org/C70219777', 'wikidata': 'https://www.wikidata.org/wiki/Q14911527', 'display_name': 'Nonsense-mediated decay', 'level': 5, 'score': 0.49049824}, {'id': 'https://openalex.org/C165864922', 'wikidata': 'https://www.wikidata.org/wiki/Q411391', 'display_name': 'Regulation of gene expression', 'level': 3, 'score': 0.48992318}, {'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.46561718}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.43219164}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.39341006}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.38509122}, {'id': 'https://openalex.org/C166703698', 'wikidata': 'https://www.wikidata.org/wiki/Q201993', 'display_name': 'RNA interference', 'level': 4, 'score': 0.33744168}, {'id': 'https://openalex.org/C54458228', 'wikidata': 'https://www.wikidata.org/wiki/Q237218', 'display_name': 'RNA splicing', 'level': 4, 'score': 0.070738345}], 'mesh': [{'descriptor_ui': 'D020868', 'descriptor_name': 'Gene Silencing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060565', 'descriptor_name': 'Argonaute Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004330', 'descriptor_name': 'Drosophila', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004330', 'descriptor_name': 'Drosophila', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004330', 'descriptor_name': 'Drosophila', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D039642', 'descriptor_name': 'Eukaryotic Initiation Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014176', 'descriptor_name': 'Protein Biosynthesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012315', 'descriptor_name': 'RNA Caps', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012315', 'descriptor_name': 'RNA Caps', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012315', 'descriptor_name': 'RNA Caps', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020871', 'descriptor_name': 'RNA Stability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/sqb.2006.71.013', 'pdf_url': 'http://symposium.cshlp.org/content/71/523.full.pdf', 'source': {'id': 'https://openalex.org/S78756772', 'display_name': 'Cold Spring Harbor Symposia on Quantitative Biology', 'issn_l': '0091-7451', 'issn': ['0091-7451', '1943-4456'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17381335', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/sqb.2006.71.013', 'pdf_url': 'http://symposium.cshlp.org/content/71/523.full.pdf', 'source': {'id': 'https://openalex.org/S78756772', 'display_name': 'Cold Spring Harbor Symposia on Quantitative Biology', 'issn_l': '0091-7451', 'issn': ['0091-7451', '1943-4456'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.53, 'display_name': 'Zero hunger', 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W144423133', 'https://openalex.org/W1971550264', 'https://openalex.org/W1976564658', 'https://openalex.org/W1976840413', 'https://openalex.org/W1978337436', 'https://openalex.org/W1992935306', 'https://openalex.org/W1993180746', 'https://openalex.org/W2017184218', 'https://openalex.org/W2030489111', 'https://openalex.org/W2032945651', 'https://openalex.org/W2034500416', 'https://openalex.org/W2041237942', 'https://openalex.org/W2041594569', 'https://openalex.org/W2049868101', 'https://openalex.org/W2058982772', 'https://openalex.org/W2060317992', 'https://openalex.org/W2074915514', 'https://openalex.org/W2076984671', 'https://openalex.org/W2095125813', 'https://openalex.org/W2096744132', 'https://openalex.org/W2115171772', 'https://openalex.org/W2117207028', 'https://openalex.org/W2127804442', 'https://openalex.org/W2131623079', 'https://openalex.org/W2138664009', 'https://openalex.org/W2139582953', 'https://openalex.org/W2142294023', 'https://openalex.org/W2144645374', 'https://openalex.org/W2146138309', 'https://openalex.org/W2146180278', 'https://openalex.org/W2152041515', 'https://openalex.org/W2152721695', 'https://openalex.org/W2152946647', 'https://openalex.org/W2154824097', 'https://openalex.org/W2158010566', 'https://openalex.org/W2159767268', 'https://openalex.org/W2160467221', 'https://openalex.org/W2161459219', 'https://openalex.org/W2162170048'], 'related_works': ['https://openalex.org/W3085855331', 'https://openalex.org/W2783495821', 'https://openalex.org/W2486487844', 'https://openalex.org/W2164554859', 'https://openalex.org/W2157957964', 'https://openalex.org/W2136897565', 'https://openalex.org/W2099927467', 'https://openalex.org/W2040257012', 'https://openalex.org/W2016298941', 'https://openalex.org/W2014028277'], 'abstract_inverted_index': {'I.': [0], 'BEHM-ANSMANT,': [1], 'J.': [2], 'REHWINKEL,': [3], 'and': [4], 'E.': [5], 'IZAURRALDE': [6], 'MPI': [7], 'for': [8], 'Developmental': [9], 'Biology,': [10], 'D-72076': [11], 'Tuebingen,': [12], 'Germany': [13]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2148842621', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 20}, {'year': 2018, 'cited_by_count': 17}, {'year': 2017, 'cited_by_count': 18}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 13}, {'year': 2014, 'cited_by_count': 15}, {'year': 2013, 'cited_by_count': 21}, {'year': 2012, 'cited_by_count': 19}], 'updated_date': '2024-09-18T16:19:20.284066', 'created_date': '2016-06-24'}