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1769, 1794, 1810, 1875, 1887, 1894, 1925, 1930, 1943, 1951, 2000, 2017, 2026, 2092, 2100, 2110, 2124, 2139, 2164, 2245, 2325, 2603, 2770, 2853, 2861, 3072, 3265, 3349, 3497, 3500, 3504, 3507, 3587, 3647, 3651, 3674, 3683, 3690, 3704, 3718, 3726, 3771, 3782, 3831, 3848, 3885, 3897, 3905, 3917, 3937, 4009, 4016, 4022, 4042, 4050, 4064, 4084, 4090, 4125, 4181, 4201, 4213, 4217, 4344, 4408], 'integral': [2, 192, 497, 742, 868, 1010, 4357], 'membrane': [3, 193, 498, 743, 869, 1011, 1088, 1140, 1171, 1176, 1221, 1256, 1331, 1352, 4348], 'proteins': [4, 25, 141, 194, 215, 331, 381, 499, 744, 829, 1354, 1408, 2251, 2988, 3160, 3370, 4205, 4341, 4360], 'that': [5, 195, 880, 942, 972, 1343, 1361, 1449, 1924, 3444, 3570, 3816, 3919, 4015, 4397, 4407], 'catalyze': [6, 196, 881], 'steps': [7, 197], 'in': [8, 20, 89, 124, 173, 198, 210, 279, 314, 363, 384, 491, 749, 831, 921, 977, 987, 1054, 1149, 1168, 1284, 1620, 1713, 1815, 1908, 1929, 2212, 2235, 2244, 2265, 2636, 2758, 2789, 3038, 3393, 3434, 3524, 3539, 3544, 3550, 3562, 3584, 3646, 3670, 3682, 3699, 3722, 3809, 3822, 3847, 3889, 3912, 3926, 3992, 4052, 4343], 'biosynthesis': [10, 200, 751], 'of': [11, 51, 75, 84, 118, 133, 137, 152, 156, 162, 171, 176, 201, 241, 265, 274, 308, 323, 327, 342, 346, 352, 361, 366, 387, 496, 504, 739, 752, 924, 1013, 1061, 1090, 1098, 1139, 1155, 1161, 1170, 1234, 1239, 1280, 1288, 1293, 1330, 1338, 1441, 1465, 1526, 1530, 1554, 1647, 1657, 1681, 1693, 1726, 1802, 1809, 1823, 1833, 1839, 1872, 1878, 1884, 1890, 1903, 2021, 2031, 2038, 2091, 2099, 2105, 2177, 2204, 2346, 2444, 2725, 2842, 2916, 3012, 3024, 3034, 3075, 3078, 3089, 3093, 3103, 3108, 3170, 3264, 3304, 3310, 3318, 3326, 3499, 3510, 3519, 3574, 3579, 3586, 3607, 3621, 3633, 3673, 3689, 3764, 3770, 3773, 3864, 3869, 3896, 3899, 3907, 4025, 4041, 4101, 4110, 4115, 4127, 4134, 4146, 4171, 4191, 4200, 4204, 4209, 4216, 4260, 4346, 4400, 4411], 'neuroendocrine': [12, 202, 1055, 1100], 'peptides': [13, 203, 506, 927], 'are': [14, 30, 204, 220, 382, 1092, 1355, 1452, 4149, 4193, 4262, 4339], 'known': [15, 205, 745], 'to': [16, 130, 180, 206, 320, 370, 746, 825, 975, 1018, 1022, 1027, 1065, 1094, 1173, 1218, 1242, 1250, 1472, 1605, 1674, 1703, 1722, 1922, 1935, 2175, 2189, 2191, 2334, 2483, 2491, 2559, 2572, 2602, 2713, 2753, 2839, 2848, 2888, 3030, 3070, 3165, 3307, 3373, 3404, 3448, 3484, 3495, 3601, 3731, 3780, 3833, 3856, 4195, 4265, 4352, 4355], 'contain': [17, 207, 871, 3571], 'routing': [18, 28, 49, 208, 218, 239, 1364, 1464], 'information': [19, 29, 209, 219], 'their': [21, 211, 3751], 'cytosolic': [22, 48, 60, 181, 212, 238, 250, 371, 815, 828, 896, 1165, 1232, 2411, 4129, 4214], 'domains,': [23, 213], 'recognizing': [26, 216], 'this': [27, 217, 1515, 1909, 4398], 'not': [31, 144, 221, 334, 3560], 'known.': [32, 222], 'Using': [33, 223, 1007, 1389], 'yeast': [35, 225, 1396, 1572], 'two-hybrid': [36, 226, 1397, 1573], 'system,': [37, 227, 1398], 'we': [38, 228, 1399, 1517, 3490, 3829, 3989, 4088], 'previously': [39, 229], 'identified': [40, 230, 1401, 1459, 1569, 1712, 3433, 4206], 'P-CIP10': [41, 56, 85, 97, 128, 148, 231, 246, 275, 287, 318, 338, 1479, 1521, 1566, 2205, 2550, 2726, 2917, 3431, 3488, 3501, 3511, 3520, 3546, 3580, 3622, 3642, 3665, 3692, 3719, 3728, 3860, 3891, 4036, 4120, 4135, 4158, 4192, 4261, 4401, 4412], 'as': [42, 160, 232, 350, 944, 1224, 1460, 1523, 1864, 2209, 2375, 2544], 'a': [43, 58, 150, 163, 233, 248, 340, 353, 864, 889, 894, 1219, 1281, 1390, 1524, 1613, 1777, 1816, 1958, 1971, 1976, 1991, 2044, 2085, 2169, 2261, 2340, 2484, 2786, 2879, 3031, 3059, 3133, 3435, 3449, 3486, 3733, 3881, 3908, 3920, 4001, 4039, 4099, 4106, 4128, 4137, 4165, 4169, 4174, 4177, 4197], 'protein': [44, 61, 234, 251, 1222, 1241, 1476, 1522, 2047, 2536, 3327, 3337, 4040, 4100], 'interacting': [45, 235], 'with': [46, 62, 236, 252, 1768, 1819, 1893, 1985, 2009, 2025, 2123, 2168, 2226, 2278, 2324, 2339, 2448, 2495, 2530, 2662, 2705, 2769, 3080, 3139, 3235, 3261, 3315, 3353, 3360, 3365, 3385, 3428, 3535, 3880, 3936, 4105, 4124, 4212], 'determinants': [50, 240], 'peptidylglycine': [52, 242, 754, 763], 'α-amidating': [53, 243, 755, 764], 'monooxygenase': [54, 244, 756], '(PAM).': [55, 245], 'is': [57, 86, 122, 247, 276, 312, 863, 919, 1063, 1142, 1333, 1444, 1467, 1470, 4067, 4121, 4402], '217-kDa': [59, 249], 'nine': [63, 253, 4417], 'spectrin-like': [64, 254, 1484, 4172], 'repeats': [65, 255, 1485], 'and': [66, 70, 98, 102, 186, 256, 260, 288, 292, 376, 490, 494, 867, 893, 928, 934, 1026, 1101, 1246, 1357, 1394, 1550, 1562, 1628, 1640, 1665, 1716, 1785, 1805, 1825, 1850, 1880, 1946, 1990, 2013, 2016, 2097, 2215, 2232, 2237, 2268, 2274, 2455, 2540, 2568, 2649, 2716, 2721, 2738, 2751, 2766, 2837, 2844, 2846, 2886, 2993, 3015, 3106, 3144, 3168, 3254, 3295, 3368, 3375, 3402, 3503, 3533, 3541, 3556, 3596, 3609, 3640, 3661, 3679, 3681, 3686, 3708, 3745, 3778, 3808, 3866, 3902, 3904, 3998, 4027, 4062, 4087, 4113, 4141, 4154, 4180, 4297, 4337, 4354, 4358, 4406], 'adjacent': [67, 257], 'Dbl': [68, 154, 258, 344, 790, 1528, 2093, 4202], 'homology': [69, 72, 259, 262, 2094, 2102, 4152], 'pleckstrin': [71, 261, 793, 2101], 'domains': [73, 170, 263, 360, 879, 4148], 'typical': [74, 264, 4145], 'GDP/GTP': [76, 266, 1531], 'exchange': [77, 267, 1532], 'factors.': [78, 268], 'In': [79, 269, 1514], 'adult': [81, 271, 1754, 2290, 2445, 3634], 'rat,': [82, 272], 'expression': [83, 273, 2041, 2087, 2129, 2724], 'most': [87, 277, 983, 2098, 4263], 'prevalent': [88, 278, 3645, 3669], 'brain.': [91, 281], 'Corticotrope': [92, 282], 'tumor': [93, 283], 'cells': [94, 110, 112, 125, 284, 300, 302, 315, 1103, 2633, 2702, 2857, 3044, 3079, 3095, 3230, 3330], 'stably': [95, 285, 1555], 'expressing': [96, 113, 286, 303, 1560, 3231, 3506], 'PAM': [99, 121, 172, 289, 311, 362, 862, 918, 973, 1014, 1062, 1091, 1141, 1172, 1235, 1289, 1294, 1332, 1353, 1466, 2409, 3575], 'produce': [100, 290], 'longer': [101, 291], 'more': [103, 293, 4068, 4081], 'highly': [104, 294], 'branched': [105, 295], 'neuritic': [106, 296], 'processes': [107, 297, 833, 3081], 'than': [108, 298, 3083, 3099, 3717, 4005, 4069, 4083], 'nontransfected': [109, 299], 'or': [111, 146, 301, 336, 1148, 1760, 2279, 2627, 2671, 2684, 2707, 2727, 2781, 2819, 2921, 3026, 3113, 3233, 3331, 3564, 3567], 'only': [114, 304, 930, 1653, 2551], 'PAM.': [115, 305], 'The': [116, 306, 1327, 1438, 1564, 1687, 1852, 1897, 2182, 2534, 3010, 3157, 3357, 3382, 3738, 3767, 3852, 3893, 3929, 4075, 4131, 4186, 4254], 'turnover': [117, 307], 'newly': [119, 309, 3849], 'synthesized': [120, 310, 2259], 'accelerated': [123, 313], 'co-expressing': [126, 316], 'P-CIP10.': [127, 317, 1563], 'binds': [129, 319], 'selected': [131, 321], 'members': [132, 322], 'Rho': [135, 325], 'subfamily': [136, 326], 'small': [138, 328, 1137], 'GTP': [139, 329], 'binding': [140, 330, 3299], '(Rac1,': [142, 332], 'but': [143, 333, 982, 3558], 'RhoA': [145, 335], 'Cdc42).': [147, 337], '(kalirin),': [149, 339], 'member': [151, 341, 1525, 4199], 'family': [155, 345, 1529, 4203], 'proteins,': [157, 347], 'may': [158, 348], 'serve': [159, 349], 'part': [161, 351, 4410], 'signal': [164, 187, 354, 377, 874, 4139], 'transduction': [165, 188, 355, 378], 'system': [166, 356, 1574, 1773, 2270, 2330], 'linking': [167, 357], 'catalytic': [169, 359, 878, 1059], 'lumen': [175, 365], 'secretory': [178, 368, 388, 989], 'pathway': [179, 369], 'factors': [182, 372, 1533], 'regulating': [183, 373], 'cytoskeleton': [185, 375], 'pathways.': [189, 379], 'Cytosolic': [380], 'involved': [383, 748, 830, 920, 4342], 'formation': [386, 950], 'granules': [389, 990], '(1Barr': [390], 'F.A.': [391, 508, 1105, 2505], 'Leyte': [392], 'A.': [393, 469, 620, 662, 3206, 3272, 3970, 4226, 4245, 4268, 4287, 4378], 'Huttner': [394, 412], 'W.B.': [395, 413], 'Trends': [396, 955], 'Cell': [397, 448, 529, 1043, 1077, 1126, 1184, 1540, 2470, 2734, 2977, 3952, 4367, 4383], 'Biol.': [398, 415, 426, 449, 530, 546, 692, 720, 847, 1078, 1127, 1185, 1201, 1264, 1312, 1374, 1423, 1499, 1541, 1588, 2067, 2390, 2421, 2511, 2584, 2611, 2900, 2934, 2953, 2978, 3188, 3218, 3284, 3413, 3467, 3953, 4325, 4368, 4384], '1992;': [399, 517, 1079, 1114, 2979], '2:': [400, 911], '91-94Abstract': [401], 'Full': [402, 431, 433, 551, 553, 697, 699, 725, 727, 852, 854, 961, 1206, 1208, 1269, 1271, 1317, 1319, 1379, 1381, 1428, 1430, 1504, 1506, 1593, 1595, 2072, 2074, 2395, 2397, 2426, 2428, 2516, 2589, 2591, 2616, 2905, 2907, 2939, 2941, 2958, 3193, 3195, 3223, 3289, 3418, 3420, 3472, 3474, 4330], 'Text': [403, 432, 434, 552, 554, 698, 700, 726, 728, 853, 855, 962, 1207, 1209, 1270, 1272, 1318, 1320, 1380, 1382, 1429, 1431, 1505, 1507, 1594, 1596, 2073, 2075, 2396, 2398, 2427, 2429, 2517, 2590, 2592, 2617, 2906, 2908, 2940, 2942, 2959, 3194, 3196, 3224, 3290, 3419, 3421, 3473, 3475, 4331], 'PDF': [404, 435, 555, 701, 729, 856, 963, 1210, 1273, 1321, 1383, 1432, 1508, 1597, 2076, 2399, 2430, 2518, 2593, 2618, 2909, 2943, 2960, 3197, 3225, 3291, 3422, 3476, 4332], 'PubMed': [405, 436, 473, 485, 534, 556, 576, 600, 629, 654, 682, 702, 730, 857, 913, 964, 1002, 1048, 1082, 1131, 1189, 1211, 1274, 1322, 1384, 1433, 1509, 1545, 1598, 1744, 2077, 2158, 2315, 2365, 2400, 2431, 2475, 2519, 2594, 2619, 2697, 2910, 2944, 2961, 2982, 3198, 3226, 3292, 3423, 3477, 3802, 3957, 3974, 4249, 4291, 4309, 4333, 4372, 4388], 'Scopus': [406, 437, 453, 474, 486, 535, 557, 577, 601, 630, 655, 683, 703, 731, 858, 914, 965, 1003, 1083, 1132, 1190, 1212, 1275, 1323, 1385, 1434, 1510, 1546, 1599, 1745, 2078, 2316, 2366, 2401, 2432, 2595, 2911, 2945, 2983, 3199, 3424, 3478, 3803, 3958, 3975, 4250, 4292, 4373, 4389], '(57)': [407], 'Google': [408, 439, 455, 476, 488, 520, 537, 559, 579, 603, 632, 657, 685, 705, 733, 860, 916, 967, 1005, 1049, 1085, 1117, 1134, 1192, 1214, 1277, 1325, 1387, 1436, 1512, 1548, 1601, 1747, 2080, 2159, 2318, 2368, 2403, 2434, 2476, 2520, 2597, 2620, 2698, 2913, 2947, 2962, 2985, 3201, 3227, 3293, 3426, 3480, 3805, 3960, 3977, 4252, 4294, 4310, 4334, 4375, 4391], 'Scholar,': [409, 420, 440, 456, 477, 521, 538, 560, 580, 604, 633, 658, 686, 706, 1118, 1193, 3202, 3961, 4311, 4376], '2Ohashi': [410], 'M.': [411, 668, 3950, 3963, 4234, 4238, 4276, 4280], 'J.': [414, 425, 447, 528, 545, 572, 596, 608, 650, 666, 678, 691, 719, 846, 1042, 1076, 1125, 1183, 1200, 1263, 1311, 1373, 1422, 1498, 1587, 2066, 2153, 2389, 2420, 2469, 2510, 2583, 2607, 2609, 2610, 2692, 2899, 2933, 2949, 2951, 2952, 2976, 3187, 3217, 3283, 3412, 3466, 3951, 4324], 'Chem.': [416, 427, 547, 693, 721, 848, 1202, 1265, 1313, 1375, 1424, 1500, 1589, 2068, 2391, 2422, 2512, 2585, 2612, 2901, 2935, 2954, 3189, 3219, 3285, 3414, 3468, 4326], '1996;': [417, 428, 548, 849, 1203, 1266, 1314, 1425, 1501, 1542, 1590, 2069, 2155, 2392, 2423, 2586, 2694, 3190, 3415, 3469, 4246, 4288, 4385], '269:': [418, 627, 2614, 2956, 3221, 3287], '24897-24905Google': [419], '3Chen': [421], 'Y.-G.': [422], 'Shields': [423], 'D.': [424, 3208, 3274, 4380], '271:': [429, 549, 850, 1204, 1267, 1315, 1426, 1502, 1591, 2070, 2393, 2424, 2587, 3191, 3416, 3470], '5297-5300Abstract': [430], '(50)': [438], '4Miller': [441], 'S.G.': [442], 'Carnell': [443], 'L.': [444, 564, 584, 2148, 2687], 'Moore': [445, 461], 'H.P.': [446], '1993;': [450, 470, 531, 910, 1128, 1186, 2513, 4306, 4369], '118:': [451], '267-283Crossref': [452], '(174)': [454], '5Chen': [457], 'Y.T.': [458], 'Holcomb': [459], 'C.': [460, 3151, 4228, 4270], 'H.P.H.': [462], 'Proc.': [463, 3964, 4239, 4281], 'Natl.': [464, 3965, 4240, 4282], 'Acad.': [465, 3966, 4241, 4283], 'Sci.': [466, 909, 957, 1044, 2471, 3967, 4242, 4284], 'U.': [467, 3968, 4243, 4285], 'S.': [468, 616, 664, 708, 3176, 3969, 4232, 4244, 4274, 4286], '90:': [471], '6508-6512Crossref': [472], '(139)': [475], '6Tooze': [478], 'S.A.': [479, 3210, 3276], 'FEBS': [480], 'Lett.': [481], '1991;': [482, 958, 3954], '285:': [483], '220-224Crossref': [484], '(65)': [487], 'Scholar)': [489, 1549, 1602, 2621, 2699, 3294, 3427], 'trafficking': [493], 'localization': [495, 1304, 1329], 'needed': [500], 'for': [501, 827, 886, 948, 1349, 1462, 1874, 1886, 2211, 2669, 2681, 2723, 2763, 2779, 2816, 3118, 3129, 3343, 3943, 4059, 4093], 'synthesis': [503], 'bioactive': [505], '(7Tausk': [507, 1104], 'Milgram': [509, 900, 1106, 1367, 2893, 2927], 'S.L.': [510, 523, 540, 901, 1033, 1071, 1107, 1120, 1178, 1195, 1258, 1306, 1368, 2415, 2460, 2578, 2894, 2928, 2971, 3407], 'Mains': [511, 524, 541, 842, 906, 993, 1038, 1074, 1108, 1121, 1179, 1196, 1259, 1307, 1418, 1494, 1583, 1738, 2062, 2151, 2309, 2359, 2385, 2416, 2465, 2579, 2690, 2974, 3408, 3462, 3796], 'R.E.': [512, 525, 542, 843, 907, 994, 1039, 1075, 1109, 1122, 1180, 1197, 1260, 1308, 1419, 1495, 1584, 1739, 2063, 2152, 2310, 2360, 2386, 2417, 2466, 2580, 2691, 2975, 3409, 3463, 3797], 'Eipper': [513, 526, 543, 844, 1040, 1110, 1123, 1181, 1198, 1261, 1309, 1371, 1420, 1496, 1585, 2064, 2387, 2418, 2467, 2508, 2581, 2897, 2931, 3410, 3464], 'B.A.': [514, 527, 544, 845, 899, 1041, 1111, 1124, 1182, 1199, 1262, 1310, 1372, 1421, 1497, 1586, 2065, 2388, 2419, 2468, 2509, 2582, 2898, 2932, 3411, 3465], 'Mol.': [515, 997, 1112], 'Endocrinol.': [516, 998, 1113], '6:': [518, 1115], '2185-2196PubMed': [519, 1116], '8Milgram': [522, 1119], '121:': [532, 1129, 1187], '23-35Crossref': [533, 1130, 1188], '(74)': [536, 1133, 1191], '9Milgram': [539, 1194], '17526-17535Abstract': [550, 1205, 1268, 1316, 2425, 2588, 3417], '(68)': [558, 1213, 1276, 1324, 2433, 2596, 3425], '10Molloy': [561], 'S.S.': [562, 586], 'Thomas': [563, 569, 583, 593], 'VanSlyke': [565], 'J.K.': [566], 'Stenberg': [567], 'P.E.': [568], 'G.': [570, 594, 3186], 'EMBO': [571, 595, 649, 677], '1994;': [573, 1741, 2312, 2362, 2613, 2955, 3220, 3286, 3799], '13:': [574], '18-33Crossref': [575], '(420)': [578], '11Jones': [581], 'B.G.': [582, 4323], 'Molloy': [585], 'Thulin': [587], 'C.D.': [588], 'Fry': [589], 'M.D.': [590], 'Walsh': [591], 'K.A.': [592], '1995;': [597, 626, 651, 679, 694, 722, 1376, 2902, 2936, 3971], '14:': [598, 652, 680], '5869-5883Crossref': [599], '(164)': [602], '12Ohno': [605], 'H.': [606, 612], 'Stewart': [607], 'Fournier': [609], 'M.-C.': [610], 'Bosshart': [611], 'Rhee': [613], 'I.': [614], 'Miyatake': [615], 'Saito': [617], 'T.': [618, 622, 710, 712, 714, 3212, 3278], 'Gallusser': [619], 'Kirchhausen': [621], 'Bonifacino': [623, 647], 'J.S.': [624, 642, 648], 'Science.': [625], '1872-1875Crossref': [628], '(826)': [631], '13Voorhees': [634], 'P.': [635, 3182, 3184], 'Deignan': [636], 'E.': [637, 640, 992, 3136], 'van': [638], 'Donselaar': [639], 'Humphrey': [641], 'Marks': [643], 'M.S.': [644], 'Peters': [645], 'P.J.': [646], '4961-4975Crossref': [653], '(187)': [656], '14Schafer': [659], 'W.': [660, 676], 'Stroh': [661], 'Berghofer': [663], 'Seiler': [665], 'Vey': [667], 'Kruse': [669], 'M.-L.': [670], 'Kern': [671], 'H.F.': [672], 'Klenk': [673], 'H.-D.': [674], 'Garten': [675], '2424-2435Crossref': [681], '(220)': [684], '15Bajjalieh': [687], 'S.M.': [688], 'Scheller': [689], 'R.H.': [690], '270:': [695, 723, 1377, 2903, 2937], '1971-1974Abstract': [696], '(185)': [704], '16Takahashi': [707], 'Nakagawa': [709], 'Banno': [711], 'Watanabe': [713], 'Murakami': [715], 'K.': [716, 718, 4230, 4272], 'Nakayama': [717], '28397-29401Abstract': [724], '(116)': [732], 'Scholar).': [734, 861, 917, 968, 1006, 1050, 1086, 1135, 1215, 1278, 1326, 1388, 1437, 1513, 1748, 2081, 2160, 2319, 2404, 2435, 2477, 2521, 2598, 2914, 2963, 2986, 3228, 3481, 3978, 4253, 4335, 4392], 'We': [735, 3724, 3995], 'have': [736, 936, 1015], 'used': [737, 760, 1604, 1721, 1814, 1921, 2208, 2543, 3491, 3725, 4089], 'one': [738], 'few': [741], 'be': [747, 4030, 4160, 4414], 'neuropeptides,': [753], '(PAM),': [757], '1The': [758], 'abbreviations': [759], 'are:': [761], 'PAM,': [762], 'monooxygenase;': [765], 'TGN,': [766, 1020], 'trans-Golgi': [767, 979], 'network;': [768], 'kb,': [769], 'kilobase': [770], 'pair(s);': [771], 'RHP,': [772, 1806], 'RACE': [773, 1719, 1778], 'hybrid': [774, 1779], 'primer;': [775], 'PCR,': [776], 'polymerase': [777], 'chain': [778], 'reaction;': [779, 2255], 'pBS,': [780, 1975], 'pBluescript': [781, 1846], 'II': [782, 1847], '(SK−);': [783], 'aa,': [784], 'amino': [785, 1159, 4071, 4103, 4189, 4257], 'acids;': [786], 'nt,': [787], 'nucleotide(s);': [788], 'DH,': [789], 'homology;': [791, 794], 'PH,': [792], 'PAGE,': [795], 'polyacrylamide': [796], 'gel': [797], 'electrophoresis;': [798], 'TES,': [799, 2828], '2-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino}ethanesulfonic': [800], 'acid;': [801], 'Ab,': [802], 'antibody;': [803, 806], 'mAb,': [804], 'monoclonal': [805], 'EST,': [807], 'expressed': [808, 1052, 2565], 'sequence': [809, 1661, 1668, 1927, 2019, 3807, 3832, 3843, 3931, 3941], 'tag;': [810], 'GST,': [811], 'glutathione': [812], 'S-transferase;': [813], 'CD,': [814], 'domain;': [816], 'LAR,': [817], 'leukocyte': [818, 4218], 'common': [819, 4002, 4219], 'antigen-related;': [820], 'MCS,': [821], 'multiple': [822], 'cloning': [823], 'site.': [824], 'search': [826, 4153], 'these': [832, 1442, 1648, 1676, 3982], '(17Alam': [834, 1410, 1486, 1575, 2054, 2377, 3454], 'M.R.': [835, 1411, 1487, 1576, 2055, 2378, 3455], 'Caldwell': [836, 1412, 1488, 1577, 2056, 2379, 3456], 'B.D.': [837, 1413, 1489, 1578, 2057, 2380, 3457], 'Johnson': [838, 1072, 1414, 1490, 1579, 2058, 2381, 2972, 3458], 'R.C.': [839, 1073, 1415, 1491, 1580, 1731, 2059, 2302, 2352, 2382, 2973, 3459, 3789], 'Darlington': [840, 1416, 1492, 1581, 1732, 2060, 2303, 2353, 2383, 3460, 3790], 'D.N.': [841, 1417, 1493, 1582, 1733, 2061, 2304, 2354, 2384, 3461, 3791], '28636-28640Abstract': [851, 1427, 1503, 1592, 2071, 2394, 3471], '(73)': [859, 1435, 1511, 1600, 2079, 2402, 3479], 'bifunctional': [865], 'enzyme': [866], 'forms': [870, 1012, 1089, 2203, 3578], 'an': [872, 1339, 1807, 1914, 2040, 2866, 3316, 3817, 3835], 'NH2-terminal': [873, 4167, 4187, 4409], 'sequence,': [875, 4140], 'two': [877, 1405, 1630, 3739, 3858], 'sequential': [883], 'reactions': [884, 1892], 'required': [885], 'peptide': [887, 984], 'amidation,': [888], 'single': [890, 3450, 3875, 3909], 'transmembrane': [891, 4147, 4222], 'domain,': [892, 4176, 4179], 'short': [895, 4166], 'domain': [897, 1060, 1166, 1233, 1287, 1342, 2096, 2104, 2412, 4215], '(18Eipper': [898], 'Husten': [902], 'E.J.': [903, 2503], 'Yun': [904], 'H.-Y.': [905, 1366, 2892, 2926], 'Protein': [908], '489-497Crossref': [912], '(231)': [915], 'production': [923], 'all': [925, 2090, 3585, 3671, 4094], 'α-amidated': [926], 'functions': [929], 'after': [931, 2552, 3124], 'neuroendocrine-specific': [932], 'endoproteases': [933], 'carboxypeptidases': [935], 'exposed': [937], 'COOH-terminal': [939, 1286, 2410, 4182], 'glycine': [940], 'residue': [941, 1283, 1347, 3911], 'serves': [943], 'nitrogen': [946], 'donor': [947], 'amide': [949], '(19Bradbury': [951], 'A.F.': [952], 'Smyth': [953], 'D.G.': [954], 'Biochem.': [956], '16:': [959, 2156, 2695], '112-115Abstract': [960], '(173)': [966], 'Immunocytochemical': [969], 'evidence': [970], 'indicates': [971], 'begins': [974], 'function': [976], 'network': [980], '(TGN),': [981], 'amidation': [985], 'occurs': [986], 'immature': [988], '(20Schnabel': [991], 'Farquhar': [995], 'M.G.': [996], '1989;': [999], '3:': [1000], '1223-1235Crossref': [1001], '(148)': [1004], 'immunoelectron': [1008], 'microscopy,': [1009], 'been': [1016, 3446], 'localized': [1017, 1093], 'especially': [1021], 'distal': [1023, 1157], 'tubuloreticular': [1024], 'regions,': [1025], 'large': [1028, 1066], 'dense': [1029, 1067], 'core': [1030, 1068], 'vesicles': [1031, 1069], '(21Milgram': [1032, 2459], 'Kho': [1034, 2461], 'S.T.': [1035, 2462], 'Martin': [1036, 2463], 'G.V.': [1037, 2464], '1997;': [1045, 2472], '110:': [1046, 2473], '695-706Crossref': [1047, 2474], 'When': [1051, 1216], 'independently': [1053], 'cells,': [1056, 3076, 3091], 'each': [1057, 3104, 3119, 3298, 3823, 3927, 3933, 4053], 'lumenal': [1058], 'targeted': [1064], '(22Milgram': [1070, 2970], '117:': [1080, 2980], '717-728Crossref': [1081, 2981], '(103)': [1084, 2984], 'Integral': [1087, 1351], 'TGN': [1096, 1244, 1303, 1328], 'region': [1097, 1245, 4170, 4183, 4399], 'both': [1099, 1840, 2714, 3774, 3890, 3900, 3913, 4060], 'nonneuroendocrine': [1102], 'A': [1136, 1827, 2127, 3515, 3618, 3874], 'percentage': [1138], 'present': [1143, 3695, 3925], 'on': [1144, 2295, 2747, 3631], 'cell': [1146, 1297, 1558, 2658, 2882, 3028, 3085, 3120, 3319, 3387, 3659], 'surface': [1147, 1298], 'endosomes': [1150], 'at': [1151, 1481, 1942, 1950, 2229, 2813, 3047, 3346, 3696, 3750, 3761, 4000, 4049], 'steady': [1152], 'state.': [1153], 'Elimination': [1154], '40': [1158, 2253], 'acids': [1160, 4104, 4190], '86-amino': [1163], 'acid': [1164, 1341, 1457, 4019, 4072, 4258], 'results': [1167], 'relocation': [1169], 'plasma': [1175, 1220, 1255, 4347], '(8Milgram': [1177], 'transferred': [1217, 2188, 2333], 'such': [1223], 'interleukin': [1226], '2': [1227, 3322, 3840, 3872, 3947, 4033, 4057, 4118], 'receptor': [1228], 'α-chain': [1229], '(Tac),': [1230], 'directs': [1236], 'majority': [1238], 'confers': [1247], 'ability': [1249], 'undergo': [1251], 'internalization': [1252, 1292], 'from': [1253, 1295, 1612, 1662, 1669, 1753, 1836, 1980, 1995, 2035, 2114, 2143, 2248, 2288, 2624, 2860, 3148, 3328, 3338, 3440, 3528, 3554, 3593, 4008], '(9Milgram': [1257, 1305, 2414, 2577, 3406], 'Mutation': [1279], 'tyrosine': [1282, 1346], 'greatly': [1290, 1334], 'diminishes': [1291], 'without': [1299, 2280], 'dramatically': [1300], 'altering': [1301], 'its': [1302, 4210], 'compromised': [1335], 'upon': [1336], 'deletion': [1337], '18-amino': [1340, 1456], 'includes': [1344], 'essential': [1348, 1461], 'internalization.': [1350], 'phosphorylated,': [1356], 'mutagenesis': [1358], 'studies': [1359], 'indicate': [1360, 4396], 'phosphorylation': [1362], 'affects': [1363], '(23Yun': [1365, 2891, 2925], 'Keutmann': [1369, 2506, 2895, 2929], 'H.T.': [1370, 2507, 2896, 2930], '30075-30083Abstract': [1378, 2904, 2938], '(33)': [1386, 2912, 2946], 'rat': [1391, 1616, 1755, 2291, 2451, 3442, 3635, 3734], 'hippocampal': [1392, 1617, 3735], 'library': [1393, 1619, 3438], 'recently': [1400], 'partial': [1402, 3712], 'cDNAs': [1403, 1649, 1690, 1954, 2206], 'encoding': [1404, 2043, 2089, 2131, 3141], 'PAMCOOH-terminal': [1406], 'interactor': [1407], '(P-CIPs)': [1409], 'biological': [1439], 'relevance': [1440], 'interactions': [1443, 1451], 'supported': [1445], 'by': [1446, 1678, 1970, 1983, 2137, 2199, 2223, 2276, 2442, 2528, 2538, 2570, 2730, 2741, 2785, 2811, 2863, 2991, 2995, 3020, 3391, 3784, 4207, 4350], 'fact': [1448], 'eliminated': [1453], 'when': [1454, 3590], 'segment': [1458], 'proper': [1463], 'eliminated.': [1468], 'P-CIP2': [1469], 'similar': [1471, 3619], 'serine/threonine': [1473], 'dual': [1474], 'specificity': [1475], 'kinases,': [1477], 'while': [1478], 'contains': [1480], 'least': [1482], 'five': [1483, 1688, 3114, 4163], 'study': [1516], 'identify': [1518], 'full-length': [1520, 2001, 2132, 2140, 2183, 2549, 3487, 3859], '(24Cerione': [1534], 'R.A.': [1535, 3214, 3280], 'Zheng': [1536, 3215, 3281], 'Y.': [1537, 3216, 3282], 'Curr.': [1538, 4381], 'Op.': [1539, 4382], '8:': [1543, 4386], '216-222Crossref': [1544], '(466)': [1547], 'establish': [1551], 'phenotype': [1553], 'transfected': [1556, 2704], 'AtT-20': [1557, 3043, 3229], 'lines': [1559, 2659, 2735], 'PAM-1': [1561, 2964, 3232, 3234], '2.0-kb': [1565, 3727], 'cDNA': [1567, 1618, 1632, 1682, 1729, 1941, 1949, 1966, 2003, 2141, 2184, 2196, 2341, 3437, 3713, 3729, 3736, 3741, 4037, 4092], 'fragment': [1568, 1830, 1900, 1978, 1993, 2034, 2113, 3730], 'using': [1570, 1776, 1798, 1866, 1957, 2179, 2260, 2348, 2709, 2878, 2967, 3002, 3050, 3058, 3132, 3379], 'was': [1603, 1711, 1720, 1765, 1813, 1842, 1862, 1920, 1933, 1968, 2007, 2023, 2052, 2117, 2135, 2172, 2186, 2197, 2221, 2242, 2293, 2322, 2337, 2372, 2440, 2481, 2526, 2542, 2557, 2622, 2965, 3313, 3432, 3522, 3548, 3559, 3599, 3624, 3629, 3714, 3776, 3820, 3845, 3887, 3924], 'screen': [1606, 3732], '1': [1607, 2774, 3084, 3513, 3615], '×': [1608, 3333], '106': [1609], 'plaque-forming': [1610], 'units': [1611], 'random': [1614], 'primed': [1615], 'λ-ZAPII': [1621], '(Stratagene).': [1622], 'Seven': [1623], 'positive': [1624], 'clones': [1625, 1658, 1714, 3775], 'were': [1626, 1635, 1650, 1685, 1691, 1699, 1955, 2207, 2258, 2634, 2660, 2703, 2718, 2736, 2756, 2794, 2820, 2858, 2989, 3000, 3018, 3045, 3056, 3116, 3127, 3146, 3161, 3237, 3259, 3351, 3363, 3371, 3389, 3582, 3612, 3644, 3667, 3694, 3747, 3759, 3786, 3854, 3987, 4047], 'plaque-purified,': [1627], 'largest': [1631, 3740], 'inserts': [1633], 'recovered': [1634], 'overlapping': [1636], '4.7-kb': [1637], '(clone': [1638, 1642], '10/28)': [1639, 3865], '4.1-kb': [1641], '10/34)': [1643, 3746, 3870], 'fragments.': [1644], 'Both': [1645], 'strands': [1646], 'sequenced': [1651], 'completely;': [1652], '5′': [1655, 1944, 1952], 'ends': [1656, 1683], '10/28': [1659, 1715, 1728, 1982, 2116], '(upstream': [1660, 1667], 'nucleotide': [1663, 1670, 3172, 3354, 3930], '36)': [1664], '10/34': [1666, 2006, 2018], '419)': [1671], 'differed.': [1672], 'Attempts': [1673], 'extend': [1675, 1723, 3781], 'sequences': [1677, 3783], '5′-rapid': [1679], 'amplification': [1680, 1797, 1879], '(RACE)': [1684], 'unsuccessful.': [1686], 'shorter': [1689, 3716], 'fragments': [1692, 3742, 3853], 'larger': [1695], 'pieces.': [1696], 'DNA': [1697, 2200], 'manipulations': [1698], 'carried': [1700, 2373], 'out': [1701, 2374], 'according': [1702], 'standard': [1704, 2180, 2349], 'protocols.': [1705], 'Since': [1706], 'no': [1707, 1856, 4142], 'in-frame': [1708, 1857, 1915, 2122, 2174, 3756, 3836], 'stop': [1709, 1858, 1916, 3757, 3837, 3882], 'codon': [1710, 3838, 3883], '10/34,': [1717], '3′': [1718, 1905], '3′-end': [1725, 3886], '(25Johnson': [1730, 2301, 2351, 3788], 'Hand': [1734, 2305, 2355, 3792], 'T.A.': [1735, 2306, 2356, 3793], 'Bloomquist': [1736, 2307, 2357, 3794], 'B.T.': [1737, 2308, 2358, 3795], 'Endocrinology.': [1740, 2311, 2361, 3798], '135:': [1742, 2313, 2363, 3800], '1178-1185Crossref': [1743, 2314, 2364, 3801], '(46)': [1746, 2317, 2367, 3804], 'Briefly,': [1749], 'poly': [1750], '(A)+': [1751], 'RNA': [1752, 2284, 2321, 2332, 3526, 3552], 'parietal': [1756, 3531, 3597], 'cortex': [1757, 3598], '(200': [1758, 2679], 'ng)': [1759, 1764], 'olfactory': [1761, 3529, 3594, 3648, 3663], 'bulb': [1762, 3595], '(140': [1763], 'reverse': [1766, 1771, 1789], 'transcribed': [1767], 'Promega': [1770, 2272, 2326], 'transcription': [1772, 2214, 2267], '(Madison,': [1774], 'WI)': [1775], 'primer': [1780], '(RHP)': [1781], '5′-GGAATTCGAGCTCATCGAT17-3′': [1782], '(0.75': [1783], 'μm)': [1784], 'avian': [1786], 'myeloblastosis': [1787], 'virus': [1788], 'transcriptase': [1790], '(15': [1791], 'units).': [1792], 'After': [1793, 3252, 3341], 'initial': [1795], '35-cycle': [1796], '5′-CAGGATGCCTTTCAAGTG-3′': [1799], '(nt': [1800, 1821, 1870, 1882, 1961, 1988, 2011, 2029, 2219, 2240], '4375–4392': [1801], 'final': [1803], 'P-CIP10a)': [1804, 1824, 1873, 1885], 'aliquot': [1808, 3317], 'PCR': [1811, 1818, 1891], 'product': [1812], 'nested': [1817], '5′-CCTCTAGAGCACCCCATCCTCAGACAAT-3′': [1820], '4592–4611': [1822], 'RHP.': [1826, 1896], '770-base': [1828], 'pair': [1829, 1899, 2112], '(674': [1831], 'nt': [1832, 1902, 2230, 2344, 4007], 'new': [1834, 1904, 4198], 'sequence)': [1835, 1906], 'independent': [1837], 'amplifications': [1838], 'tissues': [1841, 2292, 3505, 3569, 3588], 'purified,': [1843], 'subcloned': [1844, 2118, 2737], 'into': [1845, 2119, 2145, 2798, 2822, 2865, 3239, 4162, 4416], '(SK−)': [1848], '(pBS),': [1849], 'sequenced.': [1851], 'additional': [1853], '3′-sequence': [1854], 'contained': [1855, 1928], 'codon,': [1859], 'so': [1860, 4014], '3′-RACE': [1861, 1911, 1931], 'repeated': [1863], 'above': [1865], 'sense': [1867], 'primers': [1868], '5′-CTGCTTCTTCCCCCTGGTGA-3′': [1869], '5097–5116': [1871], 'first': [1876], 'round': [1877, 1889, 3090], '5′-GGTCTAGAATGGAGGCAAGTCTGAGT-3′': [1881], '5144–5164': [1883], 'second': [1888, 1910], 'same': [1895, 2246, 2771], '650-base': [1898], '(444': [1901], 'obtained': [1907, 1979, 1994, 3147], 'reaction': [1912, 4078], 'had': [1913, 3445], 'codon.': [1917], 'Reverse': [1918], 'transcriptase-PCR': [1919], 'verify': [1923], 'novel': [1926], 'products': [1932, 4024], 'contiguous': [1934], 'clone': [1936, 1981, 2005, 2115, 3485], '10/28.': [1937], 'Full-length': [1938, 1964], 'P-CIP10a': [1939, 1965, 2049, 2106, 2133, 2178, 2347, 2561, 3862, 3901, 3997, 4026, 4061, 4076, 4091, 4097], '(10/28': [1940, 3744], 'end)': [1945, 1953], 'P-CIP10b': [1947, 2002, 3867, 3903, 3999, 4028, 4085], '(10/34': [1948], 'constructed': [1956, 2136], 'PCR-generated': [1959, 2195], 'pBS.P-CIP10–3′': [1960], '4255–5724)': [1962], 'intermediate.': [1963], '(pBS.P-CIP10a)': [1967], 'created': [1969], 'three-way': [1972], 'ligation': [1973], 'ofBsp106I/BamHI-digested': [1974], '4.45-kb': [1977], 'digestion': [1984], 'Bsp106I': [1986], '(5′-MCS)-AspEI': [1987], '4401)': [1989], '1.32-kb': [1992], 'AspEI/BamHI-cut': [1996], 'pBS.P-CIP10–3′.': [1997], 'To': [1998, 2082, 2161, 3979], 'create': [1999], '(pBS.P-CIP10b),': [2004], 'digested': [2008], 'BstBI': [2010, 2022, 2028], '2674)': [2012], 'XbaI': [2014], '(3′-MCS),': [2015], 'downstream': [2020], 'replaced': [2024], '3.4-kb': [2027], '2291': [2030], 'P-CIP10a)-XbaI': [2032], '(3′-MCS)': [2033], 'pBS.P-CIP10a.': [2036], 'Construction': [2037], 'pGEX-CIP10,': [2039], 'vector': [2042, 2088, 2130], 'GST': [2045], 'fusion': [2046, 2535, 3159], 'containing': [2048, 2299, 2641, 2773, 3248, 3321], '(aa': [2050, 2108, 2453, 2488, 2532, 2562], '447–1138),': [2051], 'described': [2053, 2376], 'construct': [2083, 2162], 'pET-HisDH,': [2084], 'bacterial': [2086], '(DH)': [2095], '(PH)': [2103], '(P-CIP10a': [2107, 2487], '1254–1537)),': [2109], '857-base': [2111], 'pET28a': [2120], '(Novagen)': [2121, 2576], 'histidine': [2125], 'tag.': [2126], 'mammalian': [2128], '(pSCEP.P-CIP10a)': [2134], 'inserting': [2138], 'piece': [2142], 'pBS.P-CIP10a': [2144, 2225], 'pSCEP': [2146, 2190, 2685], '(26Paquet': [2147, 2686], 'Massie': [2149, 2688], 'B.': [2150, 2689], 'Neurosci.': [2154, 2693], '964-973Crossref': [2157, 2696], 'pBS.Myc.P-CIP10,': [2163], 'c-Myc': [2165], 'epitope': [2166, 2605], '(underlined)': [2167], 'Gly5linker': [2170], '(MEQKLISEEDLNGGGGG)': [2171], 'joined': [2173], 'Gly5': [2176], 'methods.': [2181], 'insert': [2185], 'then': [2187, 2767], 'generate': [2192], 'p.SCEP.Myc.P-CIP10.': [2193], 'All': [2194, 2632], 'confirmed': [2198], 'sequencing.': [2201], 'Truncated': [2202], 'templates': [2210], 'vitro': [2213, 2266, 3039, 3810], 'translation': [2216, 2269, 3811, 4023, 4046], 'reactions.': [2217, 3994], 'pBS.10a': [2218], '1–1142)': [2220], 'generated': [2222, 2243, 2441, 2558], 'digesting': [2224], 'BglII': [2227], '(cuts': [2228, 2234], '1142)': [2231], 'BamHI': [2233], '3′-MCS)': [2236], 'religating.': [2238], 'pBS.10b': [2239], '1–1525)': [2241], 'manner': [2247], 'pBS.P-CIP10b.': [2249], 'Radiolabeled': [2250], '([35S]methionine,': [2252], 'μCi/40-μl': [2254], 'Amersham': [2256], 'Corp.)': [2257, 2273], 'rabbit': [2262], 'reticulocyte': [2263], 'lysate': [2264], '(TNT;': [2271], 'analyzed': [2275, 3057, 3117, 3128], 'SDS-PAGE': [2277, 2539, 2992, 3374], 'prior': [2281], 'immunoprecipitation.': [2282], 'Total': [2283], '(10': [2285, 2825], 'μg)': [2286], 'prepared': [2287, 2323, 2623, 3439, 3527, 3553], 'different': [2289], 'electrophoresed': [2294], '1%': [2296, 2834, 3249, 3399], 'agarose': [2297], 'gels': [2298], 'formaldehyde': [2300], 'Poly(A)+': [2320], 'PolyATtract®': [2327], 'mRNA': [2328, 3547, 3581, 3592], 'isolation': [2329], 'II.': [2331], 'nitrocellulose': [2335], 'membranes': [2336], 'hybridized': [2338], 'probe': [2342], 'encompassing': [2343], '1363–3398': [2345], 'protocols': [2350], 'Scholar).In': [2369], 'situ': [2370, 3627], 'hybridization': [2371, 3628], 'Monoclonal': [2405, 2554, 2599], 'antibody': [2406, 2438, 2479, 2524, 2555, 2600, 3035], '6E6': [2407], 'recognizes': [2408, 2456, 2548], '(CD)': [2413], 'Rabbit': [2436, 2478, 2522], 'polyclonal': [2437, 2523], 'JH1764': [2439, 2969], 'immunization': [2443, 2529], 'female': [2446], 'rabbits': [2447], 'purified': [2449, 2537, 2569, 3158], 'recombinant': [2450, 2560], 'PHM': [2452, 2458], '37–382)': [2454], 'native': [2457], 'JH2007': [2480], 'raised': [2482, 2527, 3916], 'synthetic': [2485], 'polypeptide': [2486], '992–1013))': [2489], 'linked': [2490], 'keyhole': [2492], 'limpet': [2493], 'hemocyanin': [2494], 'glutaraldehyde': [2496], '(Hazleton': [2497], 'HRP,': [2498], 'Inc.,': [2499], 'Denver,': [2500], 'PA)': [2501], '(27Husten': [2502], 'Tausk': [2504], '268:': [2514], '9709-9717Abstract': [2515], 'JH2000': [2525, 2547, 2920, 3014], 'GST.P-CIP10a': [2531], '447–1138).': [2533], 'electroelution': [2541], 'antigen.': [2545], 'Antibody': [2546], 'denaturation.': [2553], '4C9': [2556], '1254–1537)': [2563], '(His-DH)': [2564], 'inEscherichia': [2566], 'coli': [2567, 3137], 'adsorption': [2571], 'nickel-bound': [2573], 'His-Bind': [2574], 'resin': [2575], '9E10': [2601, 2924, 3017], 'Myc': [2604, 2922], '(28Borjigin': [2606], 'Nathans': [2608, 2950], '14715-14722Abstract': [2615, 2957], 'conditioned': [2625], 'medium': [2626, 2762, 2772], 'ascites': [2628], 'fluid': [2629], '(Hazleton,': [2630], 'HRP).': [2631], 'cultured': [2635], "Dulbecco's": [2637], 'modified': [2638], 'Eagle': [2639], 'medium/F-12': [2640], '10%': [2642, 2650], 'fetal': [2643], 'bovine': [2644], 'serum': [2645, 2652], '(Hyclone,': [2646], 'Logan,': [2647], 'UT)': [2648], 'Nu': [2651], '(Collaborative': [2653], 'Research,': [2654], 'Bedford,': [2655], 'MA).': [2656], 'Transfected': [2657], 'grown': [2661, 2752], 'appropriate': [2663], 'drug': [2664], 'selection:': [2665], 'G418': [2666, 2717], '(0.5': [2667], 'mg/ml)': [2668, 3325], 'pMt.Neo': [2670], 'pMc.Neo': [2672], '(Stratagene,': [2673], 'La': [2674], 'Jolla,': [2675], 'CA)': [2676], 'cotransfections;': [2677], 'hygromycin': [2678, 2715], 'units/ml)': [2680], 'pCEP4': [2682], '(Invitrogen)': [2683], 'cotransfections.': [2700], 'AtT-20/PAM-1': [2701], 'pSCEP.P-CIP10a': [2706], 'pSCEP.Myc.P-CIP10a': [2708], 'lipofection.': [2710], 'Cells': [2711, 2745, 2793], 'resistant': [2712], 'selected,': [2719], 'expanded,': [2720], 'screened': [2722, 2740], 'Myc.P-CIP10': [2728, 3236], 'transcript': [2729, 3502], 'Northern': [2731, 2742, 3492, 3602], 'blot': [2732, 2743, 3377, 3493, 3603], 'analysis.': [2733, 2744], 'again': [2739], 'plated': [2746], '15-mm': [2748], 'culture': [2749], 'dishes': [2750, 2862], '70–90%': [2754], 'confluency': [2755], 'incubated': [2757, 3359, 3384], 'methionine/cysteine-free': [2759], 'complete': [2760, 2790], 'serum-free': [2761, 2791], '10': [2764, 2808], 'min': [2765, 2783, 2818], 'labeled': [2768], 'mCi/ml': [2775], '[35S]methionine/cysteine': [2776], '(ProMix;': [2777], 'Amersham)': [2778], '15': [2780], '30': [2782], 'followed': [2784], 'nonradioactive': [2787], 'chase': [2788], 'medium.': [2792], 'either': [2795, 3762, 3765], 'directly': [2796], 'extracted': [2797, 3238], 'SDS': [2799], 'buffer': [2800, 2824, 2868, 3268], '(1%': [2801], 'SDS,': [2802, 3400], '50': [2803, 3245, 3302, 3308, 3394], 'mm': [2804, 2809, 2826, 2832, 2870, 2875, 3241, 3246, 3395], 'Tris-HCl,': [2805, 3242, 3396], 'pH': [2806, 2829, 2872, 3243, 3397], '7.5,': [2807, 2830, 2873, 3244, 3398], 'β-mercaptoethanol)': [2810], 'incubation': [2812], '95': [2814], '°C': [2815], '5': [2817, 3332], 'scraped': [2821], 'TMT': [2823], 'sodium': [2827], '20': [2831, 3240], 'mannitol,': [2833], 'Triton': [2835, 3250], 'X-100)': [2836], 'subjected': [2838, 2887, 3372, 3403, 3447, 3600], 'three': [2840, 3256], 'cycles': [2841], 'freezing': [2843, 3253], 'thawing': [2845, 3255], 'centrifugation': [2847, 2890], 'pellet': [2849], 'insoluble': [2850], 'material.': [2851], 'For': [2852, 3297], 'subcellular': [2854], 'fractionation': [2855], 'experiment,': [2856], 'removed': [2859], 'scraping': [2864], 'isotonic': [2867], '(50': [2869], 'HEPES-KOH,': [2871], '250': [2874], 'sucrose),': [2876], 'disrupted': [2877], 'ball': [2880], 'bearing': [2881], 'cracker': [2883], '(15-μm': [2884], 'clearance),': [2885], 'differential': [2889], 'Immunoprecipitation': [2915], 'utilized': [2918], 'Ab': [2919, 2968, 3013, 3380, 3429], 'mAb': [2923, 3016], 'Scholar,28Borjigin': [2948], 'immunoprecipitated': [2966], 'Immunoprecipitated': [2987], 'resolved': [2990], 'visualized': [2994, 3523, 3561], 'fluorography.': [2996], 'Apparent': [2997], 'molecular': [2998, 3004, 4108], 'masses': [2999], 'determined': [3001, 3019], 'prestained': [3003], 'weight': [3005], 'standards': [3006], '(Rainbow': [3007], 'standards;': [3008], 'Amersham).': [3009], 'capacities': [3011], 'adding': [3021], 'increasing': [3022], 'amounts': [3023], 'AtT-20/P-CIP10a': [3025], 'AtT-20/Myc.P-CIP10': [3027], 'extract': [3029, 3320], 'fixed': [3032], 'amount': [3033], 'plus': [3036], 'radiolabeled': [3037, 3339, 3386], 'translated': [3040], 'Myc.P-CIP10.': [3041], 'Live': [3042], 'photographed': [3046], 'low': [3048], 'magnification': [3049], 'phase': [3051], 'contrast': [3052], 'optics.': [3053], 'Coded': [3054], 'images': [3055, 3115], 'BioQuant': [3060], 'TCW': [3061], '(version': [3062], '3.00;': [3063], 'R': [3064], '&': [3065], 'M': [3066], 'Biometrics,': [3067], 'Nashville,': [3068], 'TN)': [3069], 'record': [3071], 'total': [3073, 3525, 3551], 'number': [3074, 3077, 3088, 3092, 3107], '(longer': [3082], 'body': [3086, 3097], 'length),': [3087], 'giant': [3094], '(cell': [3096], 'bigger': [3098], '3': [3100, 3262, 3344], 'nuclei),': [3101], 'length': [3102], 'process,': [3105], 'bifurcations': [3109], '(branch': [3110], 'points).': [3111], 'Four': [3112], 'line': [3121], '(215–460': [3122], 'cells);': [3123], 'decoding,': [3125], 'data': [3126, 3812], 'statistical': [3130], 'significance': [3131], 't': [3134], 'test.': [3135], 'transformed': [3138], 'vectors': [3140], 'GST-Rac1,': [3142], 'GST-RhoA,': [3143], 'GST-Cdc42Hs': [3145], 'Dr.': [3149], 'Richard': [3150], 'Cerione': [3152, 3213, 3279], '(Cornell': [3153], 'University,': [3154], 'Ithaca,': [3155], 'NY).': [3156], 'prepared,': [3162], 'dialyzed,': [3163], 'bound': [3164, 3171, 3306, 3369], 'glutathione-Sepharose': [3166, 3311], 'beads,': [3167], 'depleted': [3169], '(29Hart': [3173], 'M.J.': [3174, 3204, 3270], 'Sharma': [3175], 'elMasry': [3177], 'N.': [3178], 'Qiu': [3179], 'R.-G.': [3180], 'McCabe': [3181], 'Polakis': [3183], 'Bollag': [3185], '25452-25458Abstract': [3192], '(146)': [3200], '30Hart': [3203], 'Eva': [3205, 3271], 'Zangrilli': [3207, 3273], 'Aaronson': [3209, 3275], 'Evans': [3211, 3277], '62-65Abstract': [3222, 3288], 'NaCl': [3247], 'X-100.': [3251], 'times,': [3257], 'extracts': [3258, 3362, 3388], 'diluted': [3260], 'volumes': [3263], 'guanine-nucleotide': [3266], 'depletion': [3267, 3355], '(30Hart': [3269], 'centrifuged.': [3296], 'reaction,': [3300, 4086], 'about': [3301], 'μg': [3303], 'GST-GTPase': [3305], 'μl': [3309], 'beads': [3312, 3350, 3358, 3383], 'mixed': [3314], 'mg': [3323], '(0.25': [3324], 'nonlabeled': [3329, 3361], '107': [3334], 'cpm/ml': [3335], 'acid-precipitable': [3336], 'cells.': [3340], 'mixing': [3342], 'h': [3345], '4': [3347], '°C,': [3348], 'washed': [3352], 'buffer.': [3356], 'eluted': [3364, 3390], 'Laemmli': [3366], 'buffer,': [3367], 'Western': [3376], 'analysis': [3378, 3494], 'JH2000.': [3381, 3430], 'boiling': [3392], 'diluted,': [3401], 'immunoprecipitation': [3405], 'hippocampal/cortical': [3436], '3-week-old': [3441], 'pups': [3443], 'maximal': [3451], 'electroconvulsive': [3452], 'stimulus': [3453], 'Before': [3482], 'trying': [3483], 'cDNA,': [3489], 'determine': [3496, 3980], 'size': [3498, 4043], 'highest': [3508], 'levels': [3509, 3537, 3573, 3698], '(Fig.': [3512, 3614, 3637, 3839, 3871, 3946, 4032, 4056, 4117], 'A).': [3514, 3754, 3841, 3873], 'somewhat': [3516], 'heterogeneous': [3517], 'set': [3518], 'transcripts': [3521, 3623, 3643, 3666, 3693], 'bulb,': [3530, 3649], 'cortex,': [3532, 3676, 3678], 'hippocampus,': [3534], 'lower': [3536, 3697], 'detected': [3538, 3543, 3613], 'hypothalamus': [3540], 'none': [3542], 'cerebellum.': [3545], 'detectable': [3549, 4031], 'kidney': [3555], 'spleen': [3557], 'anterior': [3563], 'neurointermediate': [3565], 'pituitary': [3566], 'atrium,': [3568], 'high': [3572], 'mRNA.': [3576], 'Multiple': [3577], 'apparent': [3583], 'examined;': [3589], 'poly(A)+': [3591], 'analysis,': [3604, 4157], 'distinct': [3605], 'bands': [3606], '8.0': [3608], '5.7': [3610], 'kb': [3611], 'A,': [3616], 'inset).': [3617], 'distribution': [3620], 'observed': [3625, 3721], 'whenin': [3626], 'performed': [3630, 3990], 'sections': [3632], 'brain': [3636], '1,': [3638], 'B': [3639], 'D).': [3641, 4119], 'including': [3650, 3703], 'internal': [3652, 3655], 'granular': [3653], 'layers,': [3654], 'plexiform': [3656], 'layer,': [3657, 3660], 'mitral': [3658], 'accessory': [3662], 'bulb.': [3664], 'also': [3668], 'layers': [3672], 'cerebral': [3675], 'piriform': [3677], 'amygdala': [3680], 'dentate': [3684], 'gyrus': [3685], 'CA1–3': [3687], 'regions': [3688, 3915], 'hippocampus.': [3691], 'several': [3700], 'hypothalamic': [3701], 'structures,': [3702], 'paraventricular,': [3705], 'supraoptic,': [3706], 'dorsomedial,': [3707], 'arcuate': [3709], 'nuclei.': [3710], 'Our': [3711], 'substantially': [3715], 'mRNAs': [3720], 'tissues.': [3723], 'library.': [3737], 'isolated': [3743], 'identical': [3748], 'except': [3749], '5′-ends': [3752, 3772], '(Fig.2': [3753, 4184], 'No': [3755, 3842], 'codons': [3758], 'found': [3760, 3846, 3888], 'end': [3763], 'cDNA.': [3766], 'GC': [3768], 'content': [3769], 'high,': [3777], 'attempts': [3779], '5′-RACE': [3785], 'unsuccessful': [3787], 'Scholar);': [3806], '(see': [3813], 'below)': [3814], 'indicated': [3815], 'initiator': [3818], 'Met': [3819, 3910, 3934, 4051, 4066], 'included': [3821], 'clone.': [3824, 3928], 'By': [3825, 4151], 'sequentially': [3826], 'employing': [3827], '3′-RACE,': [3828], 'extended': [3830], 'include': [3834], 'diversity': [3844], 'amplified': [3850], '3′-fragments.': [3851], 'assembled': [3855], 'form': [3857], 'cDNAs,': [3861], '(5′-end': [3863, 3868], 'long': [3876], 'open': [3877], 'reading': [3878], 'frame': [3879], 'near': [3884], 'cDNAs.': [3892], 'GC-rich': [3894], 'nature': [3895], '5′-end': [3898], 'presence': [3906], 'unique': [3914, 4054], 'possibility': [3918], 'transcriptional': [3921], 'start': [3922], 'site': [3923, 4003], 'surrounding': [3932], 'agreed': [3935], 'consensus': [3938], 'translational': [3939, 3984, 4011], 'initiation': [3940, 3985, 4012], 'defined': [3942], 'higher': [3944], 'eukaryotes': [3945], 'B)': [3948], '(31Kozak': [3949], '115:': [3955], '887-903Crossref': [3956], '(1451)': [3959], '32Kozak': [3962], '92:': [3972], '2662-2666Crossref': [3973], '(213)': [3976], 'whether': [3981], 'potential': [3983, 4010], 'sites': [3986, 4013], 'functional,': [3988], 'coupled': [3991], 'vitrotranscription/translation': [3993], 'truncated': [3996], 'less': [4004], '1200': [4006], 'predicted': [4017, 4044], '20-amino': [4018], 'difference': [4020], 'between': [4021], 'would': [4029], 'B).': [4034], 'Each': [4035], 'yielded': [4038], 'if': [4045], 'initiated': [4048], '5′-region': [4055], 'C);': [4058], 'P-CIP10b,': [4063], 'next': [4065, 4255], '80': [4070], 'residues': [4073, 4259], 'downstream.': [4074], 'transcription/translation': [4077], 'proceeded': [4079], 'much': [4080], 'efficiently': [4082], 'further': [4095], 'studies.': [4096], 'encodes': [4098], '1899': [4102], 'calculated': [4107], 'mass': [4109], '217': [4111], 'kDa': [4112], 'pI': [4114], '5.67': [4116], 'largely': [4122], 'hydrophilic,': [4123], 'characteristics': [4126], 'protein.': [4130], 'NH2': [4132], 'terminus': [4133], 'lacks': [4136], 'hydrophobic': [4138, 4143], 'stretches': [4144], 'present.': [4150], 'computer-based': [4155], 'structural': [4156], 'can': [4159, 4413], 'divided': [4161], 'regions:': [4164], 'region,': [4168], 'repeats,': [4173], 'DH': [4175], 'PH': [4178], 'E).': [4185], '150': [4188], 'homologous': [4194, 4264], 'Trio,': [4196], 'virtue': [4208], 'interaction': [4211], 'antigen-related': [4220], '(LAR)': [4221], 'protein-tyrosine': [4223], 'phosphatase': [4224], '(33Debant': [4225, 4267], 'Serra-Pages': [4227, 4269], 'Seipel': [4229, 4271], "O'Brien": [4231, 4273], 'Tang': [4233, 4275], 'Park': [4235, 4277], 'S.-H.': [4236, 4278], 'Streuli': [4237, 4279], '93:': [4247, 4289], '5466-5471Crossref': [4248, 4290], '(398)': [4251, 4293], '1000': [4256], 'Trio': [4266], 'Scholar),': [4295], 'spectrin,': [4296], 'fodrin': [4298, 4338], '(34Bloom': [4299], 'M.L.': [4300], 'Birkenmeier': [4301], 'C.S.': [4302], 'Baker': [4303], 'J.E.': [4304], 'Blood.': [4305], '82:': [4307], '2906-2914Crossref': [4308], '35Winkelmann': [4312], 'J.C.': [4313], 'Chang': [4314], 'J.-G.': [4315], 'Tse': [4316], 'W.T.': [4317], 'Scarpa': [4318], 'A.L.': [4319], 'Marchesi': [4320], 'V.T.': [4321], 'Forget': [4322], '1990;': [4327], '265:': [4328], '11827-11832Abstract': [4329], 'Spectrin': [4336], 'cytoskeletal': [4340], 'maintenance': [4345], 'structure': [4349, 4394], 'cross-linking': [4351], 'actin': [4353], 'various': [4356], 'membrane-associated': [4359], '(36Bennett': [4361], 'V.': [4362], 'Gilligan': [4363], 'D.M.': [4364], 'Annu.': [4365], 'Rev.': [4366], '9:': [4370], '27-66Crossref': [4371], '(444)': [4374], '37Viel': [4377], 'Branton': [4379], '49-55Crossref': [4387], '(66)': [4390], 'Secondary': [4393], 'predictions': [4395], 'almost': [4403], 'entirely': [4404], 'α-helical': [4405], 'arranged': [4415], 'spe': [4418]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2148646831', 'counts_by_year': [{'year': 2023, 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