Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2144409354', 'doi': 'https://doi.org/10.1001/jama.2013.226450', 'title': 'Barrett Esophagus and Risk of Esophageal Cancer', 'display_name': 'Barrett Esophagus and Risk of Esophageal Cancer', 'publication_year': 2013, 'publication_date': '2013-08-14', 'ids': {'openalex': 'https://openalex.org/W2144409354', 'doi': 'https://doi.org/10.1001/jama.2013.226450', 'mag': '2144409354', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23942681'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/jama.2013.226450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S172573765', 'display_name': 'JAMA', 'issn_l': '0098-7484', 'issn': ['0098-7484', '1538-3598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027327911', 'display_name': 'Stuart J. Spechler', 'orcid': 'https://orcid.org/0000-0001-5635-5386'}, 'institutions': [{'id': 'https://openalex.org/I4210104138', 'display_name': 'VA North Texas Health Care System', 'ror': 'https://ror.org/01nzxq896', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210104138', 'https://openalex.org/I4210144023']}, {'id': 'https://openalex.org/I867280407', 'display_name': 'The University of Texas Southwestern Medical Center', 'ror': 'https://ror.org/05byvp690', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I867280407']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Stuart Jon Spechler', 'raw_affiliation_strings': ['Chief of Gastroenterology, VA North Texas Healthcare System, Dallas, Texas', 'Professor of Medicine and Berta M. and Cecil O. Patterson Chair in Gastroenterology, University of Texas Southwestern Medical Center, Dallas'], 'affiliations': [{'raw_affiliation_string': 'Chief of Gastroenterology, VA North Texas Healthcare System, Dallas, Texas', 'institution_ids': ['https://openalex.org/I4210104138']}, {'raw_affiliation_string': 'Professor of Medicine and Berta M. and Cecil O. Patterson Chair in Gastroenterology, University of Texas Southwestern Medical Center, Dallas', 'institution_ids': ['https://openalex.org/I867280407']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5027327911'], 'corresponding_institution_ids': ['https://openalex.org/I4210104138', 'https://openalex.org/I867280407'], 'apc_list': None, 'apc_paid': None, 'fwci': 7.71, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 258, 'citation_normalized_percentile': {'value': 0.999666, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '310', 'issue': '6', 'first_page': '627', 'last_page': '627'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10619', 'display_name': 'Esophageal Cancer Research and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10619', 'display_name': 'Esophageal Cancer Research and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11658', 'display_name': 'Esophageal and GI Pathology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10671', 'display_name': 'Gastroesophageal reflux and treatments', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2715', 'display_name': 'Gastroenterology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/barretts-esophagus', 'display_name': "Barrett's esophagus", 'score': 0.76666784}, {'id': 'https://openalex.org/keywords/hiatal-hernia', 'display_name': 'Hiatal Hernia', 'score': 0.638694}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.94865876}, {'id': 'https://openalex.org/C2777819096', 'wikidata': 'https://www.wikidata.org/wiki/Q173710', 'display_name': 'Esophagus', 'level': 2, 'score': 0.8277364}, {'id': 'https://openalex.org/C2777014526', 'wikidata': 'https://www.wikidata.org/wiki/Q223591', 'display_name': 'GERD', 'level': 4, 'score': 0.82225966}, {'id': 'https://openalex.org/C2778589982', 'wikidata': 'https://www.wikidata.org/wiki/Q808892', 'display_name': "Barrett's esophagus", 'level': 4, 'score': 0.76666784}, {'id': 'https://openalex.org/C2775894508', 'wikidata': 'https://www.wikidata.org/wiki/Q1128996', 'display_name': 'Dysplasia', 'level': 2, 'score': 0.66309035}, {'id': 'https://openalex.org/C2778197217', 'wikidata': 'https://www.wikidata.org/wiki/Q727153', 'display_name': 'Hiatal hernia', 'level': 4, 'score': 0.638694}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.5742313}, {'id': 'https://openalex.org/C2779742542', 'wikidata': 'https://www.wikidata.org/wiki/Q372701', 'display_name': 'Esophageal cancer', 'level': 3, 'score': 0.54013115}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5307201}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.49034357}, {'id': 'https://openalex.org/C2781182431', 'wikidata': 'https://www.wikidata.org/wiki/Q356033', 'display_name': 'Adenocarcinoma', 'level': 3, 'score': 0.38418537}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.23841304}, {'id': 'https://openalex.org/C43270747', 'wikidata': 'https://www.wikidata.org/wiki/Q898610', 'display_name': 'Reflux', 'level': 3, 'score': 0.20688811}], 'mesh': [{'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D055088', 'descriptor_name': 'Early Detection of Cancer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D004945', 'descriptor_name': 'Esophagoscopy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005764', 'descriptor_name': 'Gastroesophageal Reflux', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005764', 'descriptor_name': 'Gastroesophageal Reflux', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D005764', 'descriptor_name': 'Gastroesophageal Reflux', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/jama.2013.226450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S172573765', 'display_name': 'JAMA', 'issn_l': '0098-7484', 'issn': ['0098-7484', '1538-3598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23942681', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.88, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 101, 'referenced_works': ['https://openalex.org/W1518353833', 'https://openalex.org/W1557836391', 'https://openalex.org/W1567093751', 'https://openalex.org/W1592553452', 'https://openalex.org/W1881509706', 'https://openalex.org/W1963825561', 'https://openalex.org/W1967443628', 'https://openalex.org/W1968039529', 'https://openalex.org/W1971531703', 'https://openalex.org/W1976538114', 'https://openalex.org/W1977694803', 'https://openalex.org/W1978908066', 'https://openalex.org/W1979338376', 'https://openalex.org/W1982997453', 'https://openalex.org/W1983122972', 'https://openalex.org/W1983745457', 'https://openalex.org/W1984060133', 'https://openalex.org/W1985822229', 'https://openalex.org/W1989894171', 'https://openalex.org/W1990046058', 'https://openalex.org/W1991717338', 'https://openalex.org/W1993228606', 'https://openalex.org/W1994943261', 'https://openalex.org/W1997764095', 'https://openalex.org/W1997850959', 'https://openalex.org/W1997952452', 'https://openalex.org/W1999234103', 'https://openalex.org/W2000690476', 'https://openalex.org/W2003201984', 'https://openalex.org/W2008180069', 'https://openalex.org/W2008717702', 'https://openalex.org/W2013366194', 'https://openalex.org/W2017489089', 'https://openalex.org/W2020915055', 'https://openalex.org/W2024455739', 'https://openalex.org/W2025605750', 'https://openalex.org/W2027040596', 'https://openalex.org/W2030162709', 'https://openalex.org/W2034336007', 'https://openalex.org/W2034934192', 'https://openalex.org/W2038680325', 'https://openalex.org/W2039051259', 'https://openalex.org/W2040588244', 'https://openalex.org/W2041758815', 'https://openalex.org/W2043643184', 'https://openalex.org/W2044108646', 'https://openalex.org/W2045971401', 'https://openalex.org/W2047421149', 'https://openalex.org/W2048226252', 'https://openalex.org/W2051527870', 'https://openalex.org/W2055781289', 'https://openalex.org/W2061472128', 'https://openalex.org/W2062963064', 'https://openalex.org/W2063220778', 'https://openalex.org/W2066983007', 'https://openalex.org/W2067852692', 'https://openalex.org/W2068598046', 'https://openalex.org/W2071521423', 'https://openalex.org/W2075890816', 'https://openalex.org/W2078070650', 'https://openalex.org/W2080663121', 'https://openalex.org/W2082098637', 'https://openalex.org/W2084967697', 'https://openalex.org/W2088362232', 'https://openalex.org/W2088998398', 'https://openalex.org/W2091320039', 'https://openalex.org/W2098511302', 'https://openalex.org/W2098765345', 'https://openalex.org/W2099843515', 'https://openalex.org/W2101095530', 'https://openalex.org/W2101751456', 'https://openalex.org/W2106322917', 'https://openalex.org/W2112106227', 'https://openalex.org/W2117981040', 'https://openalex.org/W2120450267', 'https://openalex.org/W2120722230', 'https://openalex.org/W2121542639', 'https://openalex.org/W2122973522', 'https://openalex.org/W212888502', 'https://openalex.org/W2135160082', 'https://openalex.org/W2138692723', 'https://openalex.org/W2141440403', 'https://openalex.org/W2146926950', 'https://openalex.org/W2150857292', 'https://openalex.org/W2151869041', 'https://openalex.org/W2152463298', 'https://openalex.org/W2152530781', 'https://openalex.org/W2154604996', 'https://openalex.org/W2154623823', 'https://openalex.org/W2156674725', 'https://openalex.org/W2160064267', 'https://openalex.org/W2161179649', 'https://openalex.org/W2167721735', 'https://openalex.org/W2168544170', 'https://openalex.org/W2168935676', 'https://openalex.org/W2170074113', 'https://openalex.org/W2171007209', 'https://openalex.org/W2186005749', 'https://openalex.org/W2354796406', 'https://openalex.org/W2399739053', 'https://openalex.org/W25460674'], 'related_works': ['https://openalex.org/W3184558599', 'https://openalex.org/W2327615825', 'https://openalex.org/W2327380017', 'https://openalex.org/W2288363208', 'https://openalex.org/W2108371578', 'https://openalex.org/W2080753493', 'https://openalex.org/W2040490968', 'https://openalex.org/W1968215035', 'https://openalex.org/W1595767777', 'https://openalex.org/W149634112'], 'abstract_inverted_index': {'Barrett': [0, 40, 64, 116, 172, 212, 217, 243, 277], 'esophagus,': [1, 41], 'a': [2, 14], 'complication': [3], 'of': [4, 34, 50, 63, 70, 75, 142, 191, 225, 251, 273], 'gastroesophageal': [5], 'reflux': [6], 'disease': [7], '(GERD),': [8], 'predisposes': [9], 'patients': [10, 149, 155, 170, 196, 204, 215, 241, 274], 'to': [11, 66, 83, 96, 193, 227], 'esophageal': [12, 143], 'adenocarcinoma,': [13], 'tumor': [15], 'that': [16], 'has': [17], 'increased': [18], 'in': [19, 115, 166, 211], 'incidence': [20, 168], 'more': [21], 'than': [22], '7-fold': [23], 'over': [24], 'the': [25, 32, 44, 48, 58, 68, 73, 89, 189, 249, 270], 'past': [26], 'several': [27], 'decades.': [28], 'Controversy': [29], 'exists': [30], 'regarding': [31], 'issues': [33], 'endoscopic': [35, 51, 76, 221], 'screening': [36, 200], 'and': [37, 47, 61, 72, 82, 88, 109, 131, 152, 232, 256], 'surveillance': [38, 222], 'for': [39, 43, 79, 113, 148, 154, 169, 195, 203, 209, 240, 253, 260, 269], 'treatment': [42, 62, 250], 'underlying': [45], 'GERD,': [46, 120], 'role': [49, 74], 'eradication': [52, 77, 182, 246, 264], 'therapy.To': [53], 'review': [54, 84, 110], 'current': [55, 85], 'concepts': [56], 'on': [57], 'pathogenesis,': [59], 'diagnosis,': [60], 'esophagus;': [65], 'discuss': [67], 'importance': [69], 'dysplasia': [71, 151, 255], 'therapy': [78, 183, 247, 265], 'its': [80], 'treatment;': [81], 'management': [86], 'guidelines.MEDLINE': [87], 'Cochrane': [90], 'Library': [91], 'were': [92, 101], 'searched': [93], 'from': [94, 106], '1984': [95], 'April': [97], '2013.': [98], 'Additional': [99], 'citations': [100], 'obtained': [102], 'by': [103], 'reviewing': [104], 'references': [105], 'selected': [107], 'research': [108], 'articles.Risk': [111], 'factors': [112, 208], 'cancer': [114, 144, 167, 194, 210], 'esophagus': [117, 173, 218], 'include': [118], 'chronic': [119], 'hiatal': [121], 'hernia,': [122], 'advanced': [123], 'age,': [124], 'male': [125], 'sex,': [126], 'white': [127], 'race,': [128], 'cigarette': [129], 'smoking,': [130], 'obesity': [132], 'with': [133, 156, 171, 184, 197, 205, 216, 275], 'an': [134, 258], 'intra-abdominal': [135], 'body': [136], 'fat': [137], 'distribution.': [138], 'The': [139], 'annual': [140], 'risk': [141, 207], 'is': [145, 176, 201, 230, 234, 239, 248, 257, 266], 'approximately': [146], '0.25%': [147], 'without': [150, 219, 242], '6%': [153], 'high-grade': [157, 198, 254], 'dysplasia.': [158, 262], 'High-quality': [159], 'studies': [160], 'have': [161], 'found': [162], 'no': [163], 'significant': [164], 'differences': [165], 'whose': [174], 'GERD': [175, 233], 'treated': [177, 235], 'medically': [178], 'or': [179], 'surgically.': [180], 'Endoscopic': [181, 245, 263], 'radiofrequency': [185], 'ablation': [186], 'significantly': [187], 'reduces': [188], 'frequency': [190], 'progression': [192], 'dysplasia.Endoscopic': [199], 'recommended': [202, 268], 'multiple': [206], 'esophagus.': [213, 244, 278], 'For': [214], 'dysplasia,': [220], 'at': [223], 'intervals': [224], '3': [226], '5': [228], 'years': [229], 'recommended,': [231], 'much': [236], 'as': [237], 'it': [238], 'choice': [252], 'option': [259], 'low-grade': [261], 'not': [267], 'general': [271], 'population': [272], 'nondysplastic': [276]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2144409354', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 15}, {'year': 2021, 'cited_by_count': 20}, {'year': 2020, 'cited_by_count': 27}, {'year': 2019, 'cited_by_count': 24}, {'year': 2018, 'cited_by_count': 20}, {'year': 2017, 'cited_by_count': 24}, {'year': 2016, 'cited_by_count': 28}, {'year': 2015, 'cited_by_count': 37}, {'year': 2014, 'cited_by_count': 39}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2025-01-04T23:31:39.054821', 'created_date': '2016-06-24'}