Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2141993375', 'doi': 'https://doi.org/10.1099/mic.0.28216-0', 'title': 'Unsaturated fatty acids are inhibitors of bacterial conjugation', 'display_name': 'Unsaturated fatty acids are inhibitors of bacterial conjugation', 'publication_year': 2005, 'publication_date': '2005-11-01', 'ids': {'openalex': 'https://openalex.org/W2141993375', 'doi': 'https://doi.org/10.1099/mic.0.28216-0', 'mag': '2141993375', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16272375'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1099/mic.0.28216-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S196799759', 'display_name': 'Microbiology', 'issn_l': '1350-0872', 'issn': ['1350-0872', '1465-2080'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320497', 'host_organization_name': 'Microbiology Society', 'host_organization_lineage': ['https://openalex.org/P4310320497'], 'host_organization_lineage_names': ['Microbiology Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1099/mic.0.28216-0', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5029443045', 'display_name': 'Raúl Fernández-López', 'orcid': 'https://orcid.org/0000-0002-9624-9059'}, 'institutions': [{'id': 'https://openalex.org/I13134134', 'display_name': 'Universidad de Cantabria', 'ror': 'https://ror.org/046ffzj20', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I13134134']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Raul Fernandez-Lopez', 'raw_affiliation_strings': ['Departamento de Biología Molecular (Unidad asociada al CIB, CSIC), Universidad de Cantabria, C. Herrera Oria s/n, E-39011 Santander, Spain'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Biología Molecular (Unidad asociada al CIB, CSIC), Universidad de Cantabria, C. Herrera Oria s/n, E-39011 Santander, Spain', 'institution_ids': ['https://openalex.org/I13134134']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089870068', 'display_name': 'Cristina Machón', 'orcid': 'https://orcid.org/0000-0001-5363-2958'}, 'institutions': [{'id': 'https://openalex.org/I13134134', 'display_name': 'Universidad de Cantabria', 'ror': 'https://ror.org/046ffzj20', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I13134134']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Cristina Machón', 'raw_affiliation_strings': ['Departamento de Biología Molecular (Unidad asociada al CIB, CSIC), Universidad de Cantabria, C. Herrera Oria s/n, E-39011 Santander, Spain'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Biología Molecular (Unidad asociada al CIB, CSIC), Universidad de Cantabria, C. Herrera Oria s/n, E-39011 Santander, Spain', 'institution_ids': ['https://openalex.org/I13134134']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016916593', 'display_name': 'Christopher Longshaw', 'orcid': 'https://orcid.org/0000-0002-5586-7256'}, 'institutions': [], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Christopher M. Longshaw', 'raw_affiliation_strings': ['Cubist Pharmaceuticals (UK) Ltd, 545 Ipswich Road, Slough SL1 4EQ, UK.'], 'affiliations': [{'raw_affiliation_string': 'Cubist Pharmaceuticals (UK) Ltd, 545 Ipswich Road, Slough SL1 4EQ, UK.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055197517', 'display_name': 'Steve Martin', 'orcid': None}, 'institutions': [], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Steve Martin', 'raw_affiliation_strings': ['Cubist Pharmaceuticals (UK) Ltd, 545 Ipswich Road, Slough SL1 4EQ, UK.'], 'affiliations': [{'raw_affiliation_string': 'Cubist Pharmaceuticals (UK) Ltd, 545 Ipswich Road, Slough SL1 4EQ, UK.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088116014', 'display_name': 'Søren Molin', 'orcid': 'https://orcid.org/0000-0002-7973-2639'}, 'institutions': [], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Soren Molin', 'raw_affiliation_strings': ['Department of Molecular Microbiology, BioCentrum-DTU, DK-2800 Lyngby, Denmark.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Microbiology, BioCentrum-DTU, DK-2800 Lyngby, Denmark.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066111566', 'display_name': 'Ellen L. Zechner', 'orcid': 'https://orcid.org/0000-0003-2035-1898'}, 'institutions': [{'id': 'https://openalex.org/I15766117', 'display_name': 'University of Graz', 'ror': 'https://ror.org/01faaaf77', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I15766117']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Ellen L. Zechner', 'raw_affiliation_strings': ['Institute of Molecular Biosciences, University of Graz, A-8010, Graz, Austria'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biosciences, University of Graz, A-8010, Graz, Austria', 'institution_ids': ['https://openalex.org/I15766117']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001922918', 'display_name': 'Manuel Espinosa', 'orcid': 'https://orcid.org/0000-0003-3958-0543'}, 'institutions': [{'id': 'https://openalex.org/I4210147680', 'display_name': 'Centro de Investigaciones Biológicas Margarita Salas', 'ror': 'https://ror.org/04advdf21', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I134820265', 'https://openalex.org/I4210147680']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Manuel Espinosa', 'raw_affiliation_strings': ['Centro de Investigaciones Biológicas (CIB), CSIC, Ramiro de Maeztu 9, E-28040 Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Centro de Investigaciones Biológicas (CIB), CSIC, Ramiro de Maeztu 9, E-28040 Madrid, Spain', 'institution_ids': ['https://openalex.org/I4210147680']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043825175', 'display_name': 'Erich Lanka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210142260', 'display_name': 'Max Planck Institute for Molecular Genetics', 'ror': 'https://ror.org/03ate3e03', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210142260']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Erich Lanka', 'raw_affiliation_strings': ['Max-Planck-Institut für Molekulare Genetik, Ihnestrasse 73, Dahlem, D-14195 Berlin, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max-Planck-Institut für Molekulare Genetik, Ihnestrasse 73, Dahlem, D-14195 Berlin, Germany', 'institution_ids': ['https://openalex.org/I4210142260']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5017358738', 'display_name': 'Fernando de la Cruz', 'orcid': 'https://orcid.org/0000-0003-4758-6857'}, 'institutions': [{'id': 'https://openalex.org/I13134134', 'display_name': 'Universidad de Cantabria', 'ror': 'https://ror.org/046ffzj20', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I13134134']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Fernando de la Cruz', 'raw_affiliation_strings': ['Departamento de Biología Molecular (Unidad asociada al CIB, CSIC), Universidad de Cantabria, C. Herrera Oria s/n, E-39011 Santander, Spain'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Biología Molecular (Unidad asociada al CIB, CSIC), Universidad de Cantabria, C. Herrera Oria s/n, E-39011 Santander, Spain', 'institution_ids': ['https://openalex.org/I13134134']}]}], 'institution_assertions': [], 'countries_distinct_count': 5, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.409, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 111, 'citation_normalized_percentile': {'value': 0.947526, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '151', 'issue': '11', 'first_page': '3517', 'last_page': '3526'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11103', 'display_name': 'Antimicrobial Peptides and Activities', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11103', 'display_name': 'Antimicrobial Peptides and Activities', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10141', 'display_name': 'Probiotics and Fermented Foods', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial biofilms and quorum sensing', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C22744801', 'wikidata': 'https://www.wikidata.org/wiki/Q172778', 'display_name': 'Plasmid', 'level': 3, 'score': 0.86579823}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.6626862}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.63744015}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.526635}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.49081025}, {'id': 'https://openalex.org/C97428945', 'wikidata': 'https://www.wikidata.org/wiki/Q15305109', 'display_name': 'Fractionation', 'level': 2, 'score': 0.48369652}, {'id': 'https://openalex.org/C161733203', 'wikidata': 'https://www.wikidata.org/wiki/Q911828', 'display_name': 'Reporter gene', 'level': 4, 'score': 0.43944028}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4332006}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.33560258}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.30528635}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.17146522}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.06951365}], 'mesh': [{'descriptor_ui': 'D003227', 'descriptor_name': 'Conjugation, Genetic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D005231', 'descriptor_name': 'Fatty Acids, Unsaturated', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D006090', 'descriptor_name': 'Gram-Negative Bacteria', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D011815', 'descriptor_name': 'R Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D003227', 'descriptor_name': 'Conjugation, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024881', 'descriptor_name': 'Drug Resistance, Bacterial', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D024881', 'descriptor_name': 'Drug Resistance, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005231', 'descriptor_name': 'Fatty Acids, Unsaturated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006090', 'descriptor_name': 'Gram-Negative Bacteria', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D006090', 'descriptor_name': 'Gram-Negative Bacteria', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006090', 'descriptor_name': 'Gram-Negative Bacteria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049449', 'descriptor_name': 'Luminescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011815', 'descriptor_name': 'R Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1099/mic.0.28216-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S196799759', 'display_name': 'Microbiology', 'issn_l': '1350-0872', 'issn': ['1350-0872', '1465-2080'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320497', 'host_organization_name': 'Microbiology Society', 'host_organization_lineage': ['https://openalex.org/P4310320497'], 'host_organization_lineage_names': ['Microbiology Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/11858/00-001M-0000-0010-8574-3', 'pdf_url': 'https://pure.mpg.de/pubman/item/item_1585410_1/component/file_1585409/Fernandez-Lopez%20et%20al.%20-%20Microbiology.pdf', 'source': {'id': 'https://openalex.org/S4306400655', 'display_name': 'MPG.PuRe (Max Planck Society)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I149899117', 'host_organization_name': 'Max Planck Society', 'host_organization_lineage': ['https://openalex.org/I149899117'], 'host_organization_lineage_names': ['Max Planck Society'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16272375', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1099/mic.0.28216-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S196799759', 'display_name': 'Microbiology', 'issn_l': '1350-0872', 'issn': ['1350-0872', '1465-2080'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320497', 'host_organization_name': 'Microbiology Society', 'host_organization_lineage': ['https://openalex.org/P4310320497'], 'host_organization_lineage_names': ['Microbiology Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.42, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1503716431', 'https://openalex.org/W1570170596', 'https://openalex.org/W1592892951', 'https://openalex.org/W1636002209', 'https://openalex.org/W1788773959', 'https://openalex.org/W1791897171', 'https://openalex.org/W1916531583', 'https://openalex.org/W193267154', 'https://openalex.org/W1943224635', 'https://openalex.org/W1966103562', 'https://openalex.org/W1973980900', 'https://openalex.org/W2000152285', 'https://openalex.org/W2001452629', 'https://openalex.org/W2038663142', 'https://openalex.org/W2042107008', 'https://openalex.org/W2046503168', 'https://openalex.org/W2067402200', 'https://openalex.org/W2072239659', 'https://openalex.org/W2079212337', 'https://openalex.org/W2083761792', 'https://openalex.org/W2103267495', 'https://openalex.org/W2105233430', 'https://openalex.org/W2118941914', 'https://openalex.org/W2119123521', 'https://openalex.org/W2121166240', 'https://openalex.org/W2126853397', 'https://openalex.org/W2159728553', 'https://openalex.org/W2164269384', 'https://openalex.org/W2171526214', 'https://openalex.org/W2416714265'], 'related_works': ['https://openalex.org/W2992955585', 'https://openalex.org/W2908588478', 'https://openalex.org/W2750385014', 'https://openalex.org/W2429129060', 'https://openalex.org/W2409844362', 'https://openalex.org/W2360987025', 'https://openalex.org/W2262337278', 'https://openalex.org/W2114870167', 'https://openalex.org/W2114174502', 'https://openalex.org/W1984664666'], 'abstract_inverted_index': {'This': [0], 'report': [1], 'describes': [2], 'a': [3, 37, 57, 64, 70, 128, 140, 165, 188, 208], 'high-throughput': [4], 'assay': [5, 49, 123], 'to': [6, 39, 126, 138, 174, 187, 191], 'identify': [7], 'substances': [8], 'that': [9, 52, 252], 'reduce': [10], 'the': [11, 24, 41, 86, 93, 193, 253], 'frequency': [12], 'of': [13, 26, 43, 60, 76, 88, 95, 110, 130, 143, 167, 195, 207, 210, 222, 234, 256, 264], 'conjugation': [14, 19, 48, 73, 77, 122], 'in': [15, 30, 82, 106], 'Gram-negative': [16], 'bacteria.': [17], 'Bacterial': [18], 'is': [20], 'largely': [21], 'responsible': [22], 'for': [23, 72], 'spread': [25, 42], 'multiple': [27], 'antibiotic': [28, 44], 'resistances': [29], 'human': [31], 'pathogens.': [32], 'Conjugation': [33], 'inhibitors': [34, 263], 'may': [35], 'provide': [36], 'means': [38], 'control': [40, 103], 'resistance.': [45], 'An': [46], 'automated': [47, 121], 'was': [50, 124, 153], 'developed': [51], 'used': [53, 125, 204], 'plasmid': [54, 115, 196, 211], 'R388': [55], 'and': [56, 67, 91, 163, 169, 201, 246], 'laboratory': [58], 'strain': [59], 'Escherichia': [61], 'coli': [62], 'as': [63, 69, 205, 261], 'model': [65], 'system,': [66], 'bioluminescence': [68], 'reporter': [71], 'activity.': [74], 'Frequencies': [75], 'could': [78, 98], 'be': [79, 99], 'measured': [80], 'continuously': [81], 'real': [83], 'time': [84], 'by': [85], 'amount': [87], 'light': [89], 'produced,': [90], 'thus': [92], 'effects': [94], 'inhibitory': [96], 'compounds': [97, 111, 145, 162, 238], 'determined': [100], 'quantitatively.': [101], 'A': [102], 'assay,': [104], 'run': [105], 'parallel,': [107], 'allowed': [108], 'elimination': [109], 'affecting': [112], 'cell': [113], 'growth,': [114], 'stability': [116], 'or': [117], 'gene': [118], 'expression.': [119], 'The': [120, 149, 180], 'screen': [127], 'database': [129], 'more': [131], 'than': [132], '12': [133], '000': [134], 'microbial': [135], 'extracts': [136, 159], 'known': [137], 'contain': [139], 'wide': [141], 'variety': [142, 166, 209], 'bioactive': [144], '(the': [146], 'NatChem': [147], 'library).': [148], 'initial': [150], 'hit': [151], 'rate': [152], '1·4': [154], '%.': [155], 'From': [156], 'these,': [157], '48': [158], 'containing': [160], 'active': [161, 183, 231], 'representing': [164], 'organisms': [168], 'extraction': [170], 'conditions': [171], 'were': [172, 185, 203, 230, 239], 'subjected': [173, 186], 'fractionation': [175], '(24': [176], 'fractions': [177, 184, 229], 'per': [178], 'extract).': [179], '52': [181], 'most': [182], 'secondary': [189], 'analysis': [190, 250], 'determine': [192], 'range': [194], 'inhibition.': [197], 'Plasmids': [198], 'R388,': [199], 'R1': [200], 'RP4': [202], 'representatives': [206], 'transfer': [212, 221], 'systems.': [213], 'Only': [214], 'one': [215], 'fraction': [216], '(of': [217], 'complex': [218], 'composition)': [219], 'affected': [220], 'all': [223], 'three': [224], 'plasmids,': [225], 'while': [226], 'four': [227], 'other': [228], 'against': [232], 'two': [233], 'them.': [235], 'Two': [236], 'separate': [237], 'identified': [240], 'from': [241], 'these': [242], 'fractions:': [243], 'linoleic': [244], 'acid': [245], 'dehydrocrepenynic': [247], 'acid.': [248], 'Downstream': [249], 'showed': [251], 'chemical': [254], 'class': [255], 'unsaturated': [257], 'fatty': [258], 'acids': [259], 'act': [260], 'true': [262], 'conjugation.': [265]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2141993375', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2025-01-09T05:05:00.724779', 'created_date': '2016-06-24'}