miRNAs as serum biomarkers for Duchenne muscular dystrophy

Name: Work Video:
Duration: 3 min 30 s
Davide Cacchiarelli; Ivano Legnini; Julie Martone; Valentina Cazzella; Adele D’Amico; Enrico Bertini; Irene Bozzoni
{'id': 'https://openalex.org/W2141619720', 'doi': 'https://doi.org/10.1002/emmm.201100133', 'title': 'miRNAs as serum biomarkers for Duchenne muscular dystrophy', 'display_name': 'miRNAs as serum biomarkers for Duchenne muscular dystrophy', 'publication_year': 2011, 'publication_date': '2011-03-01', 'ids': {'openalex': 'https://openalex.org/W2141619720', 'doi': 'https://doi.org/10.1002/emmm.201100133', 'mag': '2141619720', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21425469', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3112257'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/emmm.201100133', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/emmm.201100133', 'source': {'id': 'https://openalex.org/S163075119', 'display_name': 'EMBO Molecular Medicine', 'issn_l': '1757-4676', 'issn': ['1757-4676', '1757-4684'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/emmm.201100133', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017673527', 'display_name': 'Davide Cacchiarelli', 'orcid': 'https://orcid.org/0000-0002-9621-6716'}, 'institutions': [{'id': 'https://openalex.org/I861853513', 'display_name': 'Sapienza University of Rome', 'ror': 'https://ror.org/02be6w209', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I861853513']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Davide Cacchiarelli', 'raw_affiliation_strings': ['Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy', 'institution_ids': ['https://openalex.org/I861853513']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077676515', 'display_name': 'Ivano Legnini', 'orcid': 'https://orcid.org/0000-0002-8984-5215'}, 'institutions': [{'id': 'https://openalex.org/I861853513', 'display_name': 'Sapienza University of Rome', 'ror': 'https://ror.org/02be6w209', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I861853513']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Ivano Legnini', 'raw_affiliation_strings': ['Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy', 'institution_ids': ['https://openalex.org/I861853513']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032332050', 'display_name': 'Julie Martone', 'orcid': 'https://orcid.org/0000-0001-7864-0516'}, 'institutions': [{'id': 'https://openalex.org/I861853513', 'display_name': 'Sapienza University of Rome', 'ror': 'https://ror.org/02be6w209', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I861853513']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Julie Martone', 'raw_affiliation_strings': ['Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy', 'institution_ids': ['https://openalex.org/I861853513']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031580522', 'display_name': 'Valentina Cazzella', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I861853513', 'display_name': 'Sapienza University of Rome', 'ror': 'https://ror.org/02be6w209', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I861853513']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Valentina Cazzella', 'raw_affiliation_strings': ['Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy', 'institution_ids': ['https://openalex.org/I861853513']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008489634', 'display_name': 'Adele D’Amico', 'orcid': 'https://orcid.org/0000-0003-2438-2624'}, 'institutions': [{'id': 'https://openalex.org/I4210123352', 'display_name': "Bambino Gesù Children's Hospital", 'ror': 'https://ror.org/02sy42d13', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210123352', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': "Adele D'Amico", 'raw_affiliation_strings': ["Lab of Molecular Medicine, Department of Neuroscience, Bambino Gesù Children's Hospital, Rome, Italy"], 'affiliations': [{'raw_affiliation_string': "Lab of Molecular Medicine, Department of Neuroscience, Bambino Gesù Children's Hospital, Rome, Italy", 'institution_ids': ['https://openalex.org/I4210123352']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059742070', 'display_name': 'Enrico Bertini', 'orcid': 'https://orcid.org/0000-0001-9276-4590'}, 'institutions': [{'id': 'https://openalex.org/I4210123352', 'display_name': "Bambino Gesù Children's Hospital", 'ror': 'https://ror.org/02sy42d13', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210123352', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Enrico Bertini', 'raw_affiliation_strings': ["Lab of Molecular Medicine, Department of Neuroscience, Bambino Gesù Children's Hospital, Rome, Italy"], 'affiliations': [{'raw_affiliation_string': "Lab of Molecular Medicine, Department of Neuroscience, Bambino Gesù Children's Hospital, Rome, Italy", 'institution_ids': ['https://openalex.org/I4210123352']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015570184', 'display_name': 'Irene Bozzoni', 'orcid': 'https://orcid.org/0000-0002-3485-8537'}, 'institutions': [{'id': 'https://openalex.org/I861853513', 'display_name': 'Sapienza University of Rome', 'ror': 'https://ror.org/02be6w209', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I861853513']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Irene Bozzoni', 'raw_affiliation_strings': ['Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology and Biotechnology, Institute Pasteur Cenci‐Bolognetti and IBPM, Sapienza University of Rome, Rome, Italy', 'institution_ids': ['https://openalex.org/I861853513']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 5000, 'currency': 'USD', 'value_usd': 5000, 'provenance': 'doaj'}, 'apc_paid': {'value': 5000, 'currency': 'USD', 'value_usd': 5000, 'provenance': 'doaj'}, 'fwci': 8.294, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 250, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '3', 'issue': '5', 'first_page': '258', 'last_page': '265'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10441', 'display_name': 'Muscle Physiology and Disorders', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10441', 'display_name': 'Muscle Physiology and Disorders', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10725', 'display_name': 'RNA Interference and Gene Delivery', 'score': 0.9934, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2778943923', 'wikidata': 'https://www.wikidata.org/wiki/Q1648484', 'display_name': 'Duchenne muscular dystrophy', 'level': 2, 'score': 0.8432038}, {'id': 'https://openalex.org/C2779030066', 'wikidata': 'https://www.wikidata.org/wiki/Q1137767', 'display_name': 'Muscular dystrophy', 'level': 2, 'score': 0.59421283}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5145004}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.35315192}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.30122012}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.24633998}], 'mesh': [{'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D020388', 'descriptor_name': 'Muscular Dystrophy, Duchenne', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D020388', 'descriptor_name': 'Muscular Dystrophy, Duchenne', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003402', 'descriptor_name': 'Creatine Kinase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003402', 'descriptor_name': 'Creatine Kinase', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020388', 'descriptor_name': 'Muscular Dystrophy, Duchenne', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044967', 'descriptor_name': 'Serum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044967', 'descriptor_name': 'Serum', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/emmm.201100133', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/emmm.201100133', 'source': {'id': 'https://openalex.org/S163075119', 'display_name': 'EMBO Molecular Medicine', 'issn_l': '1757-4676', 'issn': ['1757-4676', '1757-4684'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3112257', 'pdf_url': 'https://europepmc.org/articles/pmc3112257?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112257', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21425469', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/emmm.201100133', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/emmm.201100133', 'source': {'id': 'https://openalex.org/S163075119', 'display_name': 'EMBO Molecular Medicine', 'issn_l': '1757-4676', 'issn': ['1757-4676', '1757-4684'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.8, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1733761536', 'https://openalex.org/W1788986010', 'https://openalex.org/W1967818989', 'https://openalex.org/W1972813632', 'https://openalex.org/W1985238051', 'https://openalex.org/W1991945869', 'https://openalex.org/W1992958292', 'https://openalex.org/W1996441871', 'https://openalex.org/W2009256493', 'https://openalex.org/W2010757394', 'https://openalex.org/W2045209184', 'https://openalex.org/W2051628498', 'https://openalex.org/W2068138485', 'https://openalex.org/W2070595851', 'https://openalex.org/W2072832813', 'https://openalex.org/W2075389042', 'https://openalex.org/W2078163685', 'https://openalex.org/W2084507708', 'https://openalex.org/W2086023949', 'https://openalex.org/W2098043285', 'https://openalex.org/W2110400822', 'https://openalex.org/W2113926943', 'https://openalex.org/W2115093090', 'https://openalex.org/W2121138593', 'https://openalex.org/W2155290141', 'https://openalex.org/W2157365614', 'https://openalex.org/W2158156749', 'https://openalex.org/W2163758255', 'https://openalex.org/W2322780762', 'https://openalex.org/W42578221'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2141619720', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166'], 'abstract_inverted_index': {'Report21': [0], 'March': [1], '2011Open': [2], 'Access': [3], 'miRNAs': [4, 526, 832, 880, 1386, 1444, 1468, 1504, 1579, 1727, 1771, 1980, 2337, 2490, 2508, 2607, 2735, 2785, 2827, 2837, 2862, 2876, 2917, 3105, 3157, 3175, 3430, 3559, 3659, 3885], 'as': [5, 498, 557, 722, 784, 834, 1365, 1541, 1543, 1567, 1783, 1796, 1999, 2001, 2008, 2148, 2157, 2166, 2299, 2338, 2555, 2609, 2744, 2798, 2925, 3435, 3673, 4049, 4059, 4248, 4264, 5048, 5114, 5358], 'serum': [6, 870, 1114, 1284, 1382, 1473, 1585, 2109, 2320, 2486, 2720, 2830, 3074, 3101, 3156, 3228, 3232, 3413, 3557, 3591, 3896], 'biomarkers': [7, 611, 883, 2339, 2812, 3436], 'for': [8, 33, 60, 87, 114, 138, 162, 193, 220, 247, 274, 301, 325, 349, 380, 612, 620, 643, 680, 886, 896, 920, 1154, 1161, 1458, 1520, 1524, 1534, 1544, 1768, 1867, 1977, 2302, 2340, 2481, 2612, 2634, 2732, 2813, 3263, 3342, 3437, 3453, 3733, 3783, 3899, 3904, 3916, 3939, 4032, 4125, 4133, 4143, 4150, 4223, 4287, 4330, 4391, 4484, 5052, 5080, 5203, 5207], 'Duchenne': [9, 487, 657, 931, 974, 1483, 1749, 4332, 4366, 4392, 4574, 4862, 4916, 5011, 5208, 5356], 'muscular': [10, 488, 658, 932, 981, 2410, 2922, 4333, 4367, 4393, 4438, 4575, 4705, 4746, 4833, 4863, 4917, 5012, 5211, 5363], 'dystrophy': [11, 489, 659, 933, 982, 4334, 4368, 4576], 'Davide': [12, 14, 199, 201, 388], 'Cacchiarelli': [13, 15, 200, 202, 3571, 4301], 'Department': [16, 43, 70, 97, 128, 152, 176, 203, 230, 257, 284, 315, 339, 363, 424], 'of': [17, 28, 44, 55, 71, 82, 98, 109, 125, 129, 149, 153, 177, 188, 204, 215, 231, 242, 258, 269, 285, 296, 312, 316, 336, 340, 364, 375, 405, 416, 421, 425, 449, 459, 500, 511, 521, 533, 560, 580, 584, 597, 615, 624, 647, 670, 683, 709, 733, 740, 749, 787, 826, 837, 855, 869, 889, 900, 924, 937, 1007, 1019, 1033, 1088, 1113, 1126, 1157, 1163, 1178, 1235, 1248, 1265, 1273, 1316, 1362, 1368, 1377, 1384, 1394, 1462, 1474, 1501, 1561, 1586, 1629, 1649, 1667, 1725, 1731, 1745, 1788, 1813, 1904, 1911, 1934, 2035, 2044, 2069, 2095, 2114, 2131, 2153, 2164, 2193, 2280, 2291, 2319, 2371, 2434, 2452, 2464, 2506, 2552, 2558, 2576, 2619, 2644, 2653, 2668, 2677, 2721, 2756, 2801, 2804, 2826, 2841, 2872, 2897, 2916, 2984, 3021, 3075, 3085, 3103, 3155, 3162, 3174, 3199, 3205, 3234, 3266, 3328, 3362, 3374, 3390, 3414, 3441, 3456, 3482, 3492, 3516, 3525, 3532, 3551, 3556, 3568, 3585, 3593, 3615, 3634, 3639, 3657, 3663, 3666, 3685, 3711, 3737, 3814, 3870, 3881, 3895, 3956, 3969, 3998, 4162, 4207, 4214, 4241, 4298, 4348, 4364, 4381, 4407, 4432, 4442, 4456, 4475, 4495, 4526, 4543, 4573, 4591, 4635, 4645, 4670, 4685, 4701, 4703, 4713, 4741, 4757, 4779, 4795, 4822, 4843, 4866, 4879, 4907, 4931, 4971, 5020, 5064, 5089, 5098, 5118, 5123, 5132, 5150, 5166, 5190, 5219, 5264, 5285, 5307, 5315, 5329, 5372], 'Biology': [18, 45, 72, 99, 178, 205, 232, 259, 286, 365, 406], 'and': [19, 24, 46, 51, 73, 78, 100, 105, 179, 184, 206, 211, 233, 238, 260, 265, 287, 292, 366, 371, 400, 407, 412, 452, 470, 514, 536, 605, 609, 617, 685, 744, 767, 824, 892, 943, 964, 1049, 1100, 1238, 1246, 1335, 1371, 1399, 1420, 1432, 1439, 1450, 1482, 1488, 1507, 1523, 1539, 1555, 1598, 1688, 1704, 1715, 1751, 1774, 1778, 1860, 1876, 1898, 1945, 1972, 1995, 2006, 2028, 2108, 2117, 2128, 2160, 2202, 2251, 2275, 2376, 2381, 2396, 2416, 2483, 2578, 2637, 2656, 2715, 2724, 2738, 2806, 2887, 2901, 2934, 2944, 2961, 2976, 3004, 3017, 3048, 3063, 3077, 3221, 3259, 3292, 3365, 3369, 3402, 3408, 3467, 3536, 3540, 3588, 3637, 3645, 3709, 3759, 3799, 3823, 3842, 3859, 3888, 3984, 3990, 4007, 4063, 4078, 4082, 4087, 4091, 4096, 4100, 4105, 4112, 4122, 4140, 4146, 4188, 4225, 4397, 4629, 4781, 4785, 4869, 4955, 4960, 5004, 5179, 5209, 5351], 'Biotechnology,': [20, 47, 74, 101, 180, 207, 234, 261, 288, 367, 408], 'Institute': [21, 48, 75, 102, 181, 208, 235, 262, 289, 368, 409], 'Pasteur': [22, 49, 76, 103, 182, 209, 236, 263, 290, 369, 410], 'Cenci-Bolognetti': [23, 50, 77, 104, 183, 210, 237, 264, 291, 370, 411], 'IBPM,': [25, 52, 79, 106, 185, 212, 239, 266, 293, 372, 413], 'Sapienza': [26, 53, 80, 107, 186, 213, 240, 267, 294, 373, 414], 'University': [27, 54, 81, 108, 187, 214, 241, 268, 295, 374, 415], 'Rome,': [29, 30, 56, 57, 83, 84, 110, 111, 135, 159, 189, 190, 216, 217, 243, 244, 270, 271, 297, 298, 322, 346, 376, 377, 417, 418, 431], 'Italy': [31, 58, 85, 112, 136, 160, 191, 218, 245, 272, 299, 323, 347, 378, 419, 432], 'Search': [32, 59, 86, 113, 137, 161, 192, 219, 246, 273, 300, 324, 348, 379], 'more': [34, 61, 88, 115, 139, 163, 194, 221, 248, 275, 302, 326, 350, 381, 590, 1038, 2268, 3051, 3405, 4210], 'papers': [35, 62, 89, 116, 140, 164, 195, 222, 249, 276, 303, 327, 351, 382], 'by': [36, 63, 90, 117, 141, 165, 196, 223, 250, 277, 304, 328, 352, 383, 667, 954, 1085, 1093, 1144, 1313, 1323, 1338, 1654, 1663, 2563, 2700, 2833, 3297, 3754, 3868, 3910, 3931, 4004, 4027, 4173, 4266, 4338, 4632, 5155], 'this': [37, 64, 91, 118, 142, 166, 197, 224, 251, 278, 305, 329, 353, 384, 814, 968, 1346, 2970, 3700, 5383], 'author': [38, 65, 92, 119, 143, 167, 198, 225, 252, 279, 306, 330, 354, 385, 471], 'Ivano': [39, 41, 226, 228, 390], 'Legnini': [40, 42, 227, 229], 'Julie': [66, 68, 253, 255, 392], 'Martone': [67, 69, 254, 256, 4303], 'Valentina': [93, 95, 280, 282, 394], 'Cazzella': [94, 96, 281, 283], 'Adele': [120, 122, 307, 309, 396], "D'Amico": [121, 123, 308, 310, 4982], 'Lab': [124, 148, 311, 335], 'Molecular': [126, 150, 313, 337, 422, 4196], 'Medicine,': [127, 151, 314, 338, 423], 'Neuroscience,': [130, 154, 317, 341, 426], 'Bambino': [131, 155, 318, 342, 427], 'Gesù': [132, 156, 319, 343, 428], "Children's": [133, 157, 320, 344, 429], 'Hospital,': [134, 158, 321, 345, 430], 'Enrico': [144, 146, 331, 333, 398], 'Bertini': [145, 147, 332, 334], 'Irene': [168, 172, 355, 359, 401], 'Bozzoni': [169, 173, 356, 360, 402, 4665, 4773], 'Corresponding': [170, 357], 'Author': [171, 358, 386, 4071], '[email': [174, 361], 'protected]': [175, 362], 'Information': [387, 4238], 'Cacchiarelli1,': [389], 'Legnini1,': [391], 'Martone1,': [393], 'Cazzella1,': [395], "D'Amico2,": [397], 'Bertini2': [399], '*,1': [403], '1Department': [404], '2Lab': [420], '*Tel:': [433], '+39': [434, 439], '06': [435, 440], '4991': [436, 441], '2202;': [437], 'Fax:': [438], '2500': [442], 'EMBO': [443, 4195], 'Mol': [444, 4401], 'Med': [445, 4402, 4535, 4838, 5259], '(2011)3:258-265https://doi.org/10.1002/emmm.201100133': [446], 'PDFDownload': [447], 'PDF': [448], 'article': [450], 'text': [451], 'main': [453], 'figures.': [454], 'Peer': [455], 'ReviewDownload': [456], 'a': [457, 581, 640, 662, 723, 818, 835, 917, 950, 1017, 1067, 1366, 1499, 1549, 1607, 1707, 1869, 1950, 1958, 1989, 2002, 2032, 2078, 2183, 2317, 2352, 2358, 2385, 2527, 2556, 2564, 2593, 2754, 2799, 2890, 3167, 3185, 3255, 3325, 3565, 3612, 3627, 3674, 3730, 4008, 4064, 4160, 4163, 4919, 5115, 5120, 5313], 'summary': [458], 'the': [460, 509, 519, 522, 531, 574, 578, 594, 613, 622, 645, 668, 681, 728, 747, 761, 822, 843, 853, 856, 867, 887, 898, 922, 938, 957, 972, 978, 987, 1004, 1008, 1023, 1031, 1054, 1086, 1107, 1111, 1127, 1155, 1200, 1266, 1271, 1314, 1317, 1360, 1375, 1378, 1391, 1396, 1460, 1472, 1535, 1545, 1562, 1584, 1620, 1627, 1665, 1729, 1743, 1811, 1837, 1902, 1905, 1912, 2060, 2067, 2086, 2093, 2096, 2188, 2216, 2226, 2245, 2277, 2289, 2297, 2369, 2372, 2429, 2447, 2453, 2457, 2504, 2550, 2571, 2620, 2719, 2762, 2796, 2829, 2834, 2867, 2895, 2982, 3019, 3061, 3073, 3083, 3098, 3108, 3143, 3148, 3153, 3159, 3197, 3200, 3210, 3231, 3264, 3282, 3359, 3363, 3375, 3387, 3392, 3412, 3439, 3454, 3509, 3514, 3554, 3640, 3655, 3686, 3707, 3735, 3738, 3755, 3815, 3954, 3970, 3981, 3994, 4018, 4044, 4052, 4114, 4153, 4267, 4331, 4339, 4365, 4578, 4911, 5081, 5090, 5124], 'editorial': [461, 465], 'decision': [462, 466], 'process': [463], 'including': [464, 564, 791, 2816, 2856, 3839], 'letters,': [467], 'reviewer': [468], 'comments': [469], 'responses': [472], 'to': [473, 476, 508, 538, 588, 692, 718, 850, 873, 1040, 1044, 1208, 1228, 1278, 1404, 1416, 1496, 1511, 1516, 1616, 1682, 1829, 1918, 1929, 2040, 2074, 2092, 2177, 2186, 2212, 2271, 2276, 2367, 2377, 2498, 2511, 2521, 2535, 2597, 2682, 2750, 2753, 2795, 2880, 2888, 2999, 3010, 3037, 3040, 3068, 3095, 3177, 3196, 3209, 3218, 3223, 3309, 3320, 3324, 3334, 3357, 3418, 3426, 3474, 3560, 3582, 3589, 3603, 3625, 3677, 3697, 3705, 3876, 4152, 4232, 4243], 'feedback.': [474], 'ToolsAdd': [475], 'favoritesDownload': [477], 'CitationsTrack': [478], 'CitationsPermissions': [479], 'Figures': [480], '&': [481, 1243, 2904, 3459, 3464], 'Info': [482], 'Abstract': [483], 'Dystrophin': [484, 999], 'absence': [485, 771, 1032, 1933], 'in': [486, 507, 530, 541, 627, 727, 772, 860, 956, 967, 1051, 1063, 1123, 1226, 1232, 1269, 1354, 1390, 1409, 1436, 1471, 1514, 1526, 1583, 1603, 1612, 1626, 1728, 1742, 1760, 1804, 1816, 1888, 1953, 1961, 2038, 2062, 2122, 2137, 2241, 2262, 2312, 2384, 2402, 2443, 2461, 2469, 2485, 2494, 2515, 2530, 2567, 2570, 2581, 2587, 2624, 2680, 2718, 2769, 2787, 2794, 2828, 2852, 2866, 2884, 2894, 2920, 2948, 2959, 2981, 2991, 2997, 3025, 3044, 3053, 3066, 3072, 3087, 3100, 3112, 3120, 3133, 3138, 3147, 3226, 3332, 3350, 3386, 3397, 3411, 3416, 3508, 3597, 3623, 3668, 3681, 3829, 3849, 3872, 3950, 4051, 4283, 4326, 4435, 4467, 4486, 4528, 4577, 4675, 4744, 4824, 4861, 4915, 4951, 5007, 5176, 5317, 5355], '(DMD)': [490, 660, 934, 976, 5357], 'causes': [491, 774], 'severe': [492, 663, 940, 973, 3789], 'muscle': [493, 776, 831, 838, 1009, 1035, 1045, 1090, 1355, 1369, 1726, 2070, 2197, 2281, 2292, 2439, 2465, 2553, 2600, 2645, 2861, 2873, 2885, 2899, 2950, 3289, 3352, 3377, 3429, 3442, 3558, 3594, 3635, 4433, 4448, 4487, 4630, 4954], 'degeneration.': [494, 777, 2874], 'We': [495, 4117, 4128], 'describe': [496, 817], 'that,': [497, 833, 2056], 'consequence': [499, 836, 1367, 2557, 2800], 'fibre': [501, 1010, 1421], 'damage,': [502, 839], 'specific': [503, 2048, 2788, 3042, 3658], 'muscle-miRNAs': [504], 'are': [505, 527, 607, 635, 796, 840, 912, 1060, 1120, 1287, 1311, 1336, 1469, 1580, 1781, 1793, 1802, 1808, 1841, 1984, 2146, 2170, 2204, 2254, 2441, 2491, 2509, 2742, 2759, 2978, 3023, 3286, 3313, 3725, 3846, 3975, 4025, 4246, 4253, 4261, 4336], 'released': [506, 841, 1358, 2295, 2793, 2865], 'bloodstream': [510, 2983], 'DMD': [512, 616, 632, 684, 773, 890, 909, 948, 1104, 1164, 1204, 1236, 1363, 1437, 1448, 1475, 1613, 1684, 1817, 1892, 1920, 2124, 2174, 2242, 2613, 2985, 3078, 3088, 3113, 3163, 3457, 3618, 3679, 3772, 4155, 4224, 5091], 'patients': [513, 585, 1065, 1165, 1364, 1438, 1476, 1614, 1755, 2986, 3251, 3364, 3383, 3619, 3865, 3900, 4828, 5085], 'their': [515, 846, 1372, 2178, 2988, 5277], 'levels': [516, 540, 553, 780, 795, 868, 1310, 1383, 1401, 1628, 1741, 1792, 1815, 1850, 1875, 1944, 1994, 2037, 2064, 2116, 2145, 2235, 2505, 2514, 2717, 2768, 2915, 2956, 3020, 3102, 3154, 3173, 3347, 3371, 3592], 'correlate': [517, 570, 851, 1294, 1446, 1851], 'with': [518, 573, 593, 738, 811, 852, 864, 1016, 1066, 1295, 1412, 1447, 1532, 1691, 1852, 1957, 2019, 2022, 2066, 2083, 2120, 2207, 2236, 2310, 2351, 2404, 2422, 2471, 2496, 2533, 2591, 2641, 2674, 2748, 3008, 3015, 3117, 3158, 3530, 3688, 3808, 3831, 4829, 4871, 4910, 5010, 5252, 5360], 'severity': [520, 854, 1376, 1449, 2068, 2094, 3198, 3268], 'disease.': [523, 812, 857, 1379, 3201, 4488], 'The': [524, 653, 1283, 1633, 1646, 2260, 2573, 2822, 3379, 3421, 3750, 3836, 4199], 'same': [525, 1634, 3971], 'abundant': [528, 2947, 2980, 3406], 'also': [529, 619, 895, 1175, 1388, 1637, 1702, 1794, 1842, 2171, 2585, 3137, 3433, 4129], 'blood': [532, 552, 779, 1361, 1641, 2797, 3871, 4956], 'mdx': [534, 729, 861, 1397, 1440, 2345, 2395, 2398, 2495, 2517, 2531, 2582, 2625, 2655, 2659, 2678, 2726, 2770, 3393, 3415, 3422, 3510, 3608, 3689, 3802, 3822, 3825, 4579, 4636], 'mice': [535, 862, 2500, 2626, 3511, 3690, 3803, 3867, 4094], 'recover': [537], 'wild-type': [539, 1406], 'animals': [542, 1410, 2346, 2589, 2697], '‘cured’': [543, 3691], 'through': [544, 746, 1299, 2428, 3513, 3692], 'exon': [545, 688, 714, 865, 1413, 2374, 2430, 2559, 2621, 2694, 3470, 3693, 4673], 'skipping.': [546], 'Even': [547, 905, 3610], 'though': [548, 906, 2324, 3611, 3721], 'creatine': [549, 1115, 4698], 'kinase': [550, 1116], '(CK)': [551, 1117, 5350], 'have': [554, 677, 702, 758, 781, 1221, 1250, 1329, 2182, 2285, 2877, 3450, 3485, 4204], 'been': [555, 678, 704, 782, 1222, 2781, 2878, 3451, 3486], 'utilized': [556, 783, 1457, 1566, 3356, 3672], 'diagnostic': [558, 785, 1080, 1146, 1827, 2610, 3187], 'markers': [559, 786, 1866, 2611, 2871, 5051], 'several': [561, 675, 788, 804, 2814, 2921, 3448, 3722], 'neuromuscular': [562, 789, 941, 2854, 4288], 'diseases,': [563, 790, 2815], 'DMD,': [565, 1395, 1868, 2857, 2933, 3391], 'we': [566, 600, 816, 828, 876, 1348, 2315, 2858, 2972, 3165, 3318, 3337, 3695], 'demonstrate': [567], 'that': [568, 602, 878, 1159, 1174, 1326, 1350, 1443, 1452, 1576, 1678, 1949, 2427, 2488, 2549, 2784, 2807, 2836, 2974, 3097, 3212, 3654, 4202], 'they': [569, 800, 1291, 1453, 2203, 2325, 2808, 4203], 'less': [571], 'well': [572, 1542, 2000, 3257], 'disease': [575, 598, 665, 1128, 2097, 3267, 3311, 3641, 4867], 'severity.': [576], 'Although': [577], 'analysis': [579, 1659, 1872, 2230, 3323, 3860, 3952, 4145, 5175], 'larger': [582, 3613], 'number': [583, 1785, 3327, 3927], 'should': [586], 'allow': [587], 'obtain': [589], 'refined': [591], 'correlations': [592], 'different': [595, 631, 648, 707, 908, 925, 1145, 1274, 1463, 1621, 2220, 2802, 3490, 3712, 3739, 3967, 4034], 'stages': [596, 1125], 'progression,': [599], 'propose': [601, 877, 3696], 'miR-1,': [603, 1537, 1776, 1858], 'miR-133,': [604, 1859, 2945, 3018], 'miR-206': [606, 1679, 1861, 2484, 3022, 3086, 3145, 3346, 3403], 'new': [608, 819], 'valuable': [610, 882], 'diagnosis': [614, 888, 1140, 4525], 'possibly': [618, 1456], 'monitoring': [621, 897], 'outcomes': [623, 899, 1461, 3708], 'therapeutic': [625, 633, 901, 910, 1275, 1464, 2341, 3445, 3713, 3723, 4284], 'interventions': [626, 902], 'humans.': [628, 904, 3682], 'Despite': [629], 'many': [630, 907, 2853], 'approaches': [634, 911, 3724], 'now': [636, 913, 1251, 3726], 'entering': [637, 914, 3727], 'clinical': [638, 698, 915, 1253, 1296, 1853, 2106, 2273, 3261, 3480, 3728, 4107, 4398, 4531, 4872], 'trials,': [639, 916, 3729], 'unifying': [641, 918, 3731], 'method': [642, 820, 919, 3701, 3732], 'assessing': [644, 921, 3734], 'benefit': [646, 923, 1272, 2383, 3736, 4669], 'treatments': [649, 926, 1276, 1325, 3740, 3798, 4095], 'is': [650, 661, 927, 935, 949, 991, 1001, 1082, 1105, 1110, 1141, 1206, 1277, 1680, 1758, 1909, 1955, 1975, 1997, 2050, 2135, 2267, 2561, 3215, 3236, 3270, 3506, 3741, 3953, 4159, 4192], 'still': [651, 928, 2327, 3742, 3777], 'lacking.': [652, 929, 3743], 'paper': [654], 'explained': [655, 2832], 'PROBLEM:': [656], 'genetic': [664], 'caused': [666, 953], 'lack': [669], 'functional': [671, 1333, 1916, 3160], 'dystrophin': [672, 960, 2635, 4627, 4823, 4908, 5250], '(DYS).': [673], 'Nowadays,': [674, 3447], 'strategies': [676, 1220, 3449], 'developed': [679, 3452], 'cure': [682, 3455], 'among': [686, 3468], 'them,': [687, 3469, 3667], 'skipping': [689, 715, 2370, 2431, 2560, 2622, 3471, 3505, 4674], 'has': [690, 716, 2780, 3222, 3472], 'proved': [691, 717, 3473], 'be': [693, 719, 1455, 2792, 2839, 2864, 2881, 3038, 3224, 3355, 3432, 3475, 3621, 3671, 3703], 'very': [694, 720, 1708, 2079, 2891, 3168, 3216, 3237, 3256, 3476], 'promising.': [695, 3477], 'Indeed,': [696, 3478], 'two': [697, 2246, 3479], 'phase': [699, 3483], 'I': [700, 3484, 4666, 4774, 4947], 'trials': [701, 1254, 3481], 'recently': [703, 759, 1223, 2782, 3487], 'concluded': [705, 3488], 'using': [706, 3489, 3922, 3932, 4043], 'kinds': [708, 3491], 'modified-antisense': [710, 3493], 'oligonucleotides.': [711], 'In': [712, 813, 1030, 1075, 1345, 1619, 1987, 2072, 2141, 2244, 2308, 2519, 2661, 2941, 2969, 3115, 3315, 3395, 3547, 3683, 4015], 'addition,': [713, 1988], 'effective': [721, 3507], 'gene': [724, 961, 969, 2614, 4571], 'therapy': [725, 4572], 'treatment:': [726], 'mice,': [730, 1398, 1441, 2532, 3549], 'efficient': [731, 3523], 'rescue': [732, 1229, 2433, 3524], 'DYS': [734, 770, 1230, 1418, 2379, 2435, 3526, 3552, 3569], 'was': [735, 848, 1509, 1530, 1558, 1565, 1601, 1610, 1652, 1886, 2436, 2584, 2831, 3035, 3184, 3527, 3580, 3752, 3862, 3890, 4002, 4012, 4021, 4041, 4057, 4068, 4170], 'obtained': [736, 760, 1638, 1662, 2437, 3381, 3528, 3762, 3942], 'together': [737, 2421, 3529], 'recovery': [739, 2551, 3440, 3531, 3550, 3567], 'correct': [741, 3533], 'tissue': [742, 3294, 3534], 'morphology': [743, 3535], 'integrity': [745, 1422, 2554, 3443, 3537], 'use': [748, 3515], 'AAV': [750, 3517], 'vectors': [751, 3518], 'expressing': [752, 3519], 'U1-snRNA': [753, 3520], 'antisense': [754, 2360, 3521, 4285, 5253], 'molecules.': [755], 'Such': [756, 4251], 'molecules': [757], 'Orphan': [762], 'Drug': [763], 'designation': [764], 'from': [765, 1479, 1639, 1685, 1810, 1832, 2058, 2331, 2690, 2761, 3001, 3107, 3382, 3607, 3617, 3864, 3935, 3943, 4827], 'EMEA': [766], 'FDA.': [768], 'RESULTS:': [769], 'intense': [775, 2849, 3057, 3128], 'CK': [778, 794, 1285, 1309, 1433, 2087, 2118, 2161, 2234, 2303, 2524, 2716, 2767, 3190, 3213, 3600], 'DMD.': [792], 'However,': [793, 3060], 'not': [797, 808, 884, 1288, 1293, 1328, 2264, 3131, 4256], 'reliable': [798, 1289, 3260], 'since': [799, 1290, 2053, 3254, 3647], 'vary': [801], 'considerably': [802], 'upon': [803, 3444], 'independent': [805, 3960], 'stress': [806, 3219], 'conditions,': [807, 3644], 'necessarily': [809], 'associated': [810, 1956], 'work,': [815, 1347, 3317], 'formeasuring': [821], 'onset': [823, 891], 'progression': [825, 893, 3312, 4444], 'DMD:': [827], 'identified': [829], 'three': [830, 1578, 1769, 1979, 2733, 3882], 'into': [842, 1359, 2296], 'bloodstream.': [844, 2572, 3149], 'Moreover,': [845, 1308, 2456, 2913], 'abundance': [847], 'described': [849, 2301, 2449, 3848], 'IMPACT:': [858], 'Since': [859, 2848], 'cured': [863], 'skipping,': [866, 1414, 3694], 'miRNA': [871, 1431, 1814, 1849, 1874, 1943, 1962, 1971, 1993, 2036, 2063, 2115, 2144, 2232, 2321, 2522, 2568, 2728, 2765, 3182, 3206, 3235, 3631], 'recovered': [872], 'WT': [874, 1686, 2405, 2499, 2513, 2588, 2669, 2751, 2772, 3028, 3419, 3562, 3606, 3832], 'levels,': [875, 1118, 2322, 3632], 'these': [879, 1058, 1400, 1650, 2489, 2507, 2546, 3091, 3104, 3548], 'represent': [881, 1863, 2810, 3372], 'only': [885, 3132, 3664], 'but': [894, 1701, 2021, 3136, 4255], 'on': [903, 985, 1003, 1022, 1332, 2225, 2288, 3248, 3963], 'INTRODUCTION': [930], 'one': [936, 1910, 3665], 'most': [939], 'diseases': [942, 4227], 'affects': [944], '1:3500': [945], 'live': [946], 'males.': [947], 'monogenic': [951], 'disorder': [952], 'mutations': [955, 966, 1211], '2.5': [958], 'Mb-long': [959], '(DMD).': [962], 'Deletions/duplications': [963], 'point': [965, 1210], 'cause': [970], 'either': [971], 'phenotype': [975, 1070], 'or': [977, 993, 1190, 1212, 1818, 2233, 2238, 2693, 2766, 3661, 3773, 3790, 3794, 3866, 4258, 4831], 'milder': [979], 'Becker': [980, 1064, 1753, 5210, 5361], '(BMD),': [983], 'depending': [984], 'whether': [986, 1857, 2860, 3336, 3345, 3367, 3428, 3699], 'translational': [988], 'reading': [989], 'frame': [990], 'lost': [992], 'maintained': [994], '(Hoffman': [995], 'et': [996, 1072, 1136, 1167, 1181, 1187, 1196, 1216, 1256, 1261, 1305, 1320, 1342, 1424, 1570, 1883, 2012, 2305, 2389, 2476, 2628, 2819, 2845, 2910, 2930, 2938, 2966, 3031, 3125, 3241, 3273, 3300, 3496, 3501, 3542, 3572, 3576, 3851, 3854, 4321, 4520, 4567, 4615, 4736, 4818, 4902, 4994, 5043, 5246], 'al,': [997, 1073, 1137, 1168, 1182, 1188, 1197, 1217, 1257, 1262, 1306, 1321, 1343, 1425, 1571, 1884, 2013, 2306, 2390, 2477, 2629, 2820, 2846, 2911, 2931, 2939, 2967, 3032, 3126, 3242, 3274, 3301, 3497, 3502, 3543, 3573, 3577, 3855], '1988).': [998, 1074], '(DYS)': [1000, 2636], 'localized': [1002, 1021], 'inner': [1005], 'face': [1006], 'plasma': [1011], 'membrane,': [1012], 'linking': [1013], 'cytoskeletal': [1014], 'actin': [1015], 'complex': [1018, 1028], 'proteins': [1020, 2679], 'sarcolemma,': [1024], 'named': [1025], 'DYS-associated': [1026], 'protein': [1027, 2670, 4097], '(DAPC).': [1029], 'DYS,': [1034], 'fibres': [1036, 2466, 3141], 'become': [1037], 'sensitive': [1039, 2811, 2870, 3217], 'mechanical': [1041], 'damage': [1042, 2601], 'leading': [1043], 'degeneration,': [1046], 'chronic': [1047], 'inflammation': [1048], 'increase': [1050, 1609, 1960, 2034, 2061, 2529, 3065, 3084], 'fibrosis,': [1052], 'exacerbating': [1053], 'dystrophic': [1055, 1734, 1833, 2963, 2992, 3026, 3054, 3121, 4676], 'phenotype.': [1056], 'All': [1057, 1764, 1800, 2740], 'traits': [1059], 'clearly': [1061], 'attenuated': [1062], 'mild': [1068, 2528], 'myopathic': [1069], '(Monaco': [1071], 'boys': [1076, 4218, 5009], 'under': [1077, 1492, 1836, 3763], '5': [1078, 1752, 2666, 5188], 'years,': [1079], 'investigation': [1081], 'usually': [1083], 'triggered': [1084], 'presence': [1087], 'abnormal': [1089], 'function': [1091, 2902, 4631], 'manifested': [1092], "Gowers'": [1094], 'sign,': [1095], 'calf': [1096], 'hypertrophy,': [1097], 'toe': [1098], 'walking,': [1099], 'waddling': [1101], 'gait.': [1102], 'When': [1103], 'suspected,': [1106], 'first': [1108, 3983], 'assessment': [1109, 2107, 2201, 3262], 'measurement': [1112], 'which': [1119, 1974, 2076, 3192], 'markedly': [1121], 'increased': [1122, 1337, 1381], 'early': [1124], '(10–100': [1129], 'fold': [1130, 1797, 2745, 3006], 'higher': [1131, 2328], 'than': [1132, 1590, 2329, 3189, 3786], 'healthy': [1133, 1587, 1732, 1821, 1831, 2332, 3002], 'controls;': [1134], 'Ebashi': [1135, 4688], '1959).': [1138], 'Genetic': [1139], 'currently': [1142], 'assessed': [1143, 4003], 'procedures:': [1147], 'multiplex': [1148, 1170, 1191, 4371, 5156], 'polymerase': [1149], 'chain': [1150], 'reaction': [1151], '(PCR)': [1152], 'assay': [1153], 'identifications': [1156], 'deletions': [1158, 5088], 'account': [1160], '65%': [1162], '(Chamberlain': [1166], '1988);': [1169], 'ligation-dependent': [1171, 5157], 'probe': [1172, 1193, 1551, 5158], 'amplification': [1173], 'allows': [1176], 'identification': [1177], 'insertions': [1179], '(Schouten': [1180], '2002);': [1183], 'Southern': [1184], 'blotting': [1185], '(Stockley': [1186, 1215], '2006)': [1189], 'amplifiable': [1192], 'hybridization': [1194], '(Dent': [1195], '2005).': [1198, 1572], 'If': [1199], 'mutation': [1201], 'remains': [1202], 'unidentified,': [1203], 'sequencing': [1205], 'required': [1207, 3622], 'find': [1209, 1279], 'small': [1213, 4622], 'insertions/deletions': [1214], '2006).': [1218], 'Several': [1219, 2875], 'set': [1224, 2752, 4076], 'up': [1225, 4077], 'order': [1227, 1515, 2681, 3333, 3624], 'synthesis': [1231, 1419, 2380, 2990, 4628], 'animal': [1233, 1392, 3388, 4126], 'models': [1234], '(Aartsma-Rus': [1237, 3458], 'van': [1239, 1259, 2908, 3460, 3499, 4278, 5222, 5240, 5267, 5288], 'Ommen,': [1240, 3461], '2010;': [1241, 2907, 3462, 3574], 'Cossu': [1242, 3463, 4384], 'Sampaolesi,': [1244, 3465], '2007)': [1245, 3466], 'some': [1247], 'them': [1249, 2194], 'entered': [1252], '(Kinali': [1255, 3495], '2009;': [1258, 3498], 'Deutekom': [1260, 3500, 5223], '2007).': [1263, 2940, 3503], 'One': [1264], 'major': [1267], 'problems': [1268], 'comparing': [1270, 1739, 2713, 3152], 'common': [1280], 'outcome': [1281, 2342], 'measurements.': [1282], 'values': [1286, 1408, 1780, 1801, 1840, 2088, 2119, 2162, 2729, 2747, 3341], 'do': [1292, 1327], 'assessments': [1297, 1854], 'measured': [1298, 3225, 3296], 'magnetic': [1300], 'resonance': [1301], 'imaging': [1302], '(MRI;': [1303], 'Kim': [1304, 4846], '2010).': [1307, 2014, 2821, 2968, 3033, 3275, 3302], 'influenced': [1312], 'age': [1315, 1996, 2005, 2132, 2179, 2237], 'child': [1318], '(Zatz': [1319, 2304], '1991),': [1322], 'pharmacological': [1324], 'any': [1330, 3780], 'effect': [1331], 'status': [1334], 'physical': [1339], 'activity': [1340, 2451, 3214, 4700, 4868], '(Malm': [1341], '2000).': [1344], 'showed': [1349], 'microRNAs,': [1351], 'specifically': [1352, 2882], 'expressed': [1353, 2786, 2883, 3349], 'cells,': [1356], 'were': [1357, 1387, 1402, 1490, 1631, 1636, 1766, 2222, 2326, 2347, 2400, 2419, 2672, 2698, 2730, 2918, 2952, 3246, 3384, 3404, 3761, 3804, 3827, 3908, 3920, 3929], 'degeneration': [1370, 2850, 3110, 3129, 3636], 'amount': [1373, 2290], 'paralleled': [1374, 3553], 'Notably,': [1380, 2503, 3181, 3564], 'muscle-specific': [1385, 1536], 'found': [1389, 1611, 2919, 2953], 'model': [1393, 3389, 3423], 'lowered': [1403], 'almost': [1405, 1581, 1692, 2512, 2994, 3561], '(WT)': [1407], 'treated': [1411, 2590, 2658], 'known': [1415], 'restore': [1417, 2378], '(Denti': [1423, 2388, 2475, 2627, 3853], '2006a,': [1426, 2478, 3544, 3578], '2006b,': [1427, 3545], '2008).': [1428, 2479, 2847, 3243, 3546, 3856], 'Comparison': [1429], 'between': [1430, 1486, 1873, 1896, 1942, 1970, 1992, 2004, 2105, 2126, 2764, 3630, 4000, 4039, 5084], 'measurements,': [1434, 3290], 'both': [1435, 1553, 2958, 3400], 'indicated': [1442, 2206, 2487], 'better': [1445, 3186], 'suggest': [1451], 'can': [1454, 2284, 2791, 2809, 3338, 3354, 3431, 3670, 3702], 'measuring': [1459], 'interventions.': [1465, 3446, 3714], 'RESULTS': [1466], 'Muscle': [1467, 2606], 'enriched': [1470, 2493, 2996, 3007], 'Serum': [1477, 1848, 3861, 5112, 5348], 'samples': [1478, 2330, 3000, 3968], 'healthy,': [1480, 1747], 'Becker,': [1481], 'children,': [1484], 'ranging': [1485], '1-': [1487, 5187], '16-years-old,': [1489], 'collected': [1491, 2420, 4102], 'informed': [1493], 'consensus.': [1494, 3765], 'Prior': [1495, 3875], 'RNA': [1497, 1642, 3857, 3877, 4080, 4624], 'extraction,': [1498, 3878], 'cocktail': [1500], 'artificial': [1502, 3884, 3936], 'spiked': [1503, 1770, 2734, 3883], '(ath-miR-159a,': [1505, 1772, 2736, 3886], 'cel-lin-2,': [1506, 1773, 2737], 'cel-lin-4)': [1508, 3889], 'added': [1510, 3891], 'each': [1512, 2142, 3892], 'sample': [1513], 'normalize': [1517], 'raw': [1518], 'data': [1519, 1765, 2741, 3616, 3948], 'qRT-PCR': [1521, 1529, 2480, 3919, 3951, 4086, 4134], 'efficiency': [1522], 'variability': [1525], 'volume': [1527], 'handling.': [1528], 'performed': [1531, 1887, 3247, 3921, 3930, 3962, 4079, 4085, 4093, 4106], 'probes': [1533], 'miR-206,': [1538, 1777, 2579], 'miR-133': [1540, 1705, 1779, 2977, 3370], 'spikes.': [1546], 'For': [1547, 2215, 3276, 4209], 'mir-133,': [1548], 'single': [1550], 'recognizing': [1552], 'miR-133a': [1554], 'miR-133b': [1556], 'isoforms': [1557], 'utilized.': [1559], 'Quantification': [1560], 'granulocyte-specific': [1563], 'miR-223': [1564, 1630, 1791], 'control': [1568, 2662, 2896], '(Fazi': [1569], 'Figure': [1573, 1721, 1936, 1965, 2102, 2604], '1A': [1574, 4017], 'shows': [1575, 1938, 1967], 'all': [1577, 1978, 2192], 'undetectable': [1582], 'controls': [1588, 2333], '(less': [1589], '10ˆ3': [1591, 1597], 'copies/ml).': [1592, 1618], 'A': [1593, 3202, 4054, 4776], 'moderate': [1594, 3791], 'enrichment': [1595], '(between': [1596], '10ˆ4': [1599], 'copies/ml)': [1600], 'detected': [1602], 'BMD': [1604, 1689, 1819, 3011, 3076, 3774], 'individuals': [1605], 'while': [1606, 3230], 'considerable': [1608], '(up': [1615], '10ˆ6': [1617], 'samples,': [1622], 'no': [1623, 3304, 3788, 4205], 'significant': [1624, 1976], 'differences': [1625, 3099, 3999, 5083], 'observed.': [1632], 'results': [1635, 1676, 2547, 3092, 3380, 3687], 'whole': [1640], 'preparations': [1643], '(not': [1644, 2602], 'shown).': [1645, 2603], 'statistical': [1647, 1710, 2539, 4088], 'significance': [1648, 2540, 3997], 'measurements': [1651, 2343], 'confirmed': [1653, 2586, 3385], 'receiver': [1655], 'operating': [1656], 'characteristics': [1657], '(ROC)': [1658], '(Fig': [1660, 2098, 2467, 2501, 2541], '1B)': [1661], 'plotting': [1664, 4028], 'rate': [1666], 'true': [1668], 'positive': [1669, 1673], '(sensitivity)': [1670], 'versus': [1671, 1733, 1820, 2771, 3027, 4030], 'false': [1672], '(1-specificity).': [1674], 'These': [1675], 'show': [1677, 2077, 2089, 2973], 'able': [1681, 3581], 'discriminate': [1683, 3605], '(healthy)': [1687], 'cases': [1690, 3331], 'absolute': [1693, 3940], 'specificity': [1694], '(AUC': [1695, 1712], 'always': [1696, 1713, 1985], '>0.94,': [1697], 'p': [1698, 1718, 4009, 4065], '<': [1699, 1719, 4010, 4066], '0.001)': [1700], 'miR-1': [1703, 2482, 2577, 2943, 2975, 3016, 3368, 3401], 'display': [1706], 'good': [1709, 3169], 'score': [1711, 1919, 1947, 2210], '>0.84': [1714], '>0.76,': [1716], 'respectively,': [1717, 3071], '0.01).': [1720], '1.': [1722, 2757], 'Differential': [1723], 'amounts': [1724], 'sera': [1730, 1744, 3760, 4104, 4702], 'children.': [1735, 2243], 'A..': [1736, 2111, 2616], 'Box': [1737, 2711, 3973], 'plots': [1738, 2712], 'microRNA': [1740, 2714, 4485, 4742], '7': [1746], '26': [1748], '(DMD),': [1750], '(BMD)': [1754, 5362], '(patient': [1756, 2133], 'information': [1757, 2134, 4191, 4211], 'listed': [1759, 2136], 'supplementary': [1761, 2138], 'Table': [1762, 2139], '1).': [1763, 2140, 2336], 'normalized': [1767, 2731, 3938], 'cel-lin-4).': [1775, 2739], 'shown': [1782, 1795, 1803, 1982, 2147, 2442, 2743, 2879, 3036, 3949], 'copy': [1784], 'per': [1786], 'ml': [1787], 'serum.': [1789], 'Control': [1790], 'change': [1798, 2746], 'values.': [1799], 'logarithmic': [1805], 'scale.': [1806], 'p-values': [1807, 1983, 2252, 2758], 'derived': [1809, 2760], 'comparison': [1812, 2039, 2113, 2520, 2763, 2998, 3417], 'patients.': [1822], 'B..': [1823, 2228, 2631], 'ROC': [1824, 4023], 'curves': [1825, 3934, 4024], 'regarding': [1826], 'power': [1828], 'distinguish': [1830], 'cases.': [1834], 'Area': [1835], 'curve': [1838, 5174], '(AUC)': [1839], 'shown.': [1843], 'Download': [1844, 1846, 2256, 2258, 2774, 2776], 'figure': [1845, 2257, 2775], 'PowerPoint': [1847, 2259, 2777], 'To': [1855], 'study': [1856, 3427, 3751], 'could': [1862, 2838, 2863], 'bona': [1864], 'fide': [1865], 'case-by-case': [1870], 'correlation': [1871, 1941, 1969, 1991, 2003, 2082, 3629, 4046, 4055, 4870], 'North': [1877, 4732, 4997], 'Star': [1878, 4998], 'Ambulatory': [1879, 4999], 'Assessment': [1880], '(NSAA,': [1881], 'Mazzone': [1882, 4974], '2010)': [1885], '10': [1889, 2123], 'ambulating': [1890, 3643], 'young': [1891, 3122, 3249, 4217], 'children': [1893, 2125, 3784], '(age': [1894], 'range': [1895], '3': [1897, 2127], '6': [1899, 2129], 'years)': [1900, 3253], 'at': [1901, 2199, 2954, 3957, 3964, 4194], 'time': [1903, 3646], 'molecular': [1906, 4327, 4524, 5205], 'diagnosis.': [1907], 'NSAA': [1908, 1946, 1954, 2084, 2121, 2155, 2209, 2239, 3280], 'actual': [1913], '‘gold': [1914], 'standard’': [1915], 'tests': [1917, 3308], 'motor': [1921, 2024], 'ability': [1922, 2025], '(from': [1923], 'value': [1924, 1930, 2755], '34': [1925], '–': [1926, 1932, 3901], 'normal': [1927, 2196, 2213], 'ambulation,': [1928], '0': [1931], 'ambulation).': [1935], '2A': [1937], 'an': [1939, 4060, 4529], 'inverse': [1940, 2081, 3170], 'indicating': [1948, 3977], 'progressive': [1951, 2278, 4704], 'decrease': [1952, 2318, 2566, 3555], 'gradual': [1959], 'serological': [1963, 3873], 'levels.': [1964, 3563], '2B': [1966], 'Spearman': [1968, 2229, 2248, 4045], 'NSAA,': [1973, 2007], '(the': [1981], '<0.05).': [1986], 'direct': [1990], 'observed': [1998, 2316, 2580, 3144, 3166], 'previously': [2009, 2300, 2365, 2448], 'reported': [2010, 2366, 2783], '(Mazzone': [2011, 3272], 'Interestingly,': [2015, 3150], 'patient': [2016, 2218, 3776], 'DMD10,': [2017, 2219], 'coetaneous': [2018], 'DMD9': [2020, 2041], 'worst': [2023], '(NSAA': [2026], '16': [2027], '25,': [2029], 'respectively),': [2030], 'displays': [2031, 3193], '26-fold': [2033], '(right': [2042], 'panel': [2043], 'Fig': [2045, 2335, 2363, 2444, 4016], '2A).': [2046], 'This': [2047, 2283, 3034, 3715, 4168], 'case': [2049], 'quite': [2051], 'interesting': [2052], 'it': [2054], 'suggests': [2055], 'independently': [2057], 'age,': [2059], 'correlates': [2065], 'damage.': [2071], 'contrast': [2073], 'miRNAs,': [2075], 'clear': [2080], 'scores,': [2085], 'fluctuations': [2090, 3194], 'unrelated': [2091, 3195], '2A,': [2099], 'lower': [2100], 'panel).': [2101, 2544], '2.': [2103], 'Correlation': [2104], 'miRNAs.': [2110, 3595], 'Case-by-case': [2112], 'years': [2130], 'graph,': [2143], 'white': [2149], 'dots': [2150], '(copy': [2151], 'numbers/ml': [2152], 'serum),': [2154], 'scores': [2156, 2240], 'black': [2158], 'dots,': [2159], '(units/ml': [2163], 'serum)': [2165], 'diamonds;': [2167], 'regression': [2168], 'lines': [2169], 'displayed.': [2172, 2255], 'Patients': [2173, 4156], '1–3,': [2175], 'due': [2176, 2270, 3039], '(3': [2180], 'years),': [2181], 'non-collaborative': [2184], 'behaviour': [2185], 'perform': [2187], 'entire': [2189], 'NSAA;': [2190], 'however,': [2191], 'had': [2195], 'strength': [2198], 'neurological': [2200], 'indeed': [2205], 'maximum': [2208, 3991], 'according': [2211], 'ambulation.': [2214], 'outlier': [2217], 'scales': [2221], 'used': [2223, 2596], '(graphs': [2224], 'right).': [2227], 'correlating': [2231], 'tables,': [2247], 'coefficients': [2249], '(R)': [2250], '(p)': [2253], 'situation': [2261], 'older,': [2263], 'ambulant': [2265, 3179, 3250, 3778, 5008], 'patients,': [2266, 2314, 3079, 3164, 3278], 'complicated': [2269], 'heterogeneous': [2272], 'conditions': [2274, 2583, 3220, 3680], 'loss': [2279], 'mass.': [2282, 3378], 'strong': [2286], 'effects': [2287], 'cellular': [2293], 'material': [2294], 'blood,': [2298], '1991).': [2307], 'agreement': [2309, 2470, 3116], 'this,': [2311], 'older': [2313], 'even': [2323, 3662, 3720], '(supplementary': [2334], 'Six-week-old': [2344, 3801], 'tail': [2348, 3805], 'vein': [2349, 3806], 'injected': [2350, 3807], 'recombinant': [2353], 'adeno-associated': [2354, 4619, 4671], 'viral': [2355], 'vector': [2356], 'carrying': [2357], 'U1-chimeric': [2359], 'construct': [2361], '(AAV#23,': [2362], '3A),': [2364], 'induce': [2368, 2598], 'mutated': [2373], '23': [2375], 'morpho-functional': [2382, 3586], 'body-wide': [2386, 2450], 'manner': [2387], '2006a).': [2391, 2630], 'After': [2392, 3819], '1': [2393, 3820, 3879], 'month,': [2394, 3821], 'AAV#23-treated': [2397, 2516, 2725, 3824], 'siblings': [2399, 3826], 'sacrificed': [2401, 3828], 'parallel': [2403, 3830], 'isogenic/aged': [2406, 3833], 'matched': [2407, 3834], 'animals.': [2408, 2773, 3835], 'Different': [2409], 'districts': [2411, 2440], '[gastrocnemius': [2412], '(GAS),': [2413], 'diaphragm': [2414], '(DIA),': [2415], 'heart': [2417], '(HEA)]': [2418], 'sera.': [2423], 'Western': [2424, 2632, 3843], 'blot': [2425, 2633, 3844], 'revealed': [2426], 'treatment,': [2432], '(representative': [2438], '3B),': [2445], 'confirming': [2446], 'AAV#23': [2454, 2458], 'virus.': [2455], 'administration': [2459], 'resulted': [2460], 'morphological': [2462], 'amelioration': [2463, 3584], '3C)': [2468], 'our': [2472, 3322, 3651], 'previous': [2473, 3118], 'findings': [2474], '20/40-fold': [2492], 'respect': [2497, 2534, 2749, 3009, 3067], '3D).': [2502], 'rescued': [2510], 'mice.': [2518, 2727, 3609, 4637, 4677], 'quantifications,': [2523], 'titration': [2525, 3601], 'reveals': [2526, 5312], 'WT,': [2536, 2654, 2722], 'without': [2537, 3779], 'relevant': [2538, 4329], '3D,': [2542], 'right': [2543], 'Altogether,': [2545], 'indicate': [2548, 3653], 'accompanied': [2562], 'drastic': [2565], 'release': [2569, 2575, 3146], 'conspicuous': [2574], 'cardiotoxin,': [2592], 'drug': [2594], 'normally': [2595], 'acute': [2599], '3.': [2605], '(dystromiR)': [2608], 'therapy.': [2615], 'Schematic': [2617], 'representation': [2618], 'strategy': [2623], 'actinin': [2638], '(ACTN)': [2639], 'perfomed': [2640], '50': [2642, 3902], 'µg': [2643, 2667, 2676], 'extracts': [2646], '(GAS,': [2647], 'gastrocnemius;': [2648], 'HEA,': [2649], 'heart;': [2650], 'DIA,': [2651], 'diaphragm)': [2652], 'AAV-U1#23': [2657, 3816], '(AAV#23).': [2660, 3818], 'lane': [2663], '(wild-type;': [2664], 'WT),': [2665], 'extract': [2671], 'mixed': [2673], '45': [2675], 'avoid': [2683], 'signal': [2684], 'saturation.': [2685], 'C..': [2686], 'Mdx': [2687], 'gastrocnemius': [2688], 'sections': [2689], 'untreated': [2691], '(mock)': [2692], 'skipping-treated': [2695], '(AAV#23)': [2696], 'analysed': [2699], 'Hematoxylin/Eosin': [2701], 'staining.': [2702], 'Original': [2703], 'magnification': [2704], '20×.': [2705], 'Scale': [2706], 'bar:': [2707], '100': [2708], 'µm.': [2709], 'D..': [2710], 'mdx,': [2723], 'DISCUSSION': [2778], 'It': [2779], 'body': [2789], 'compartments': [2790], 'types': [2803], 'injuries': [2805], 'cancer': [2817, 5053], '(Schöler': [2818], 'surprisingly': [2823], 'high': [2824, 3172], 'stability': [2825, 3233], 'observation': [2835], 'part': [2840], 'exosomal': [2842], 'particles': [2843], '(Mitchell': [2844, 3240], 'occurrs': [2851], 'disorders,': [2855], 'tested': [2859], 'serum,': [2868, 3669], 'representing': [2869], 'cells': [2886, 3047], 'play': [2889], 'crucial': [2892], 'role': [2893, 5314], 'proper': [2898], 'development': [2900], '(Crist': [2903], 'Buckingham,': [2905], '2009,': [2906], 'Rooij': [2909, 2929, 5268, 5289], '2008a).': [2912], 'altered': [2914], 'disorders': [2923], 'such': [2924, 3329], 'myocardial': [2926, 5310], 'infarction': [2927, 5311], '(van': [2928], '2008b),': [2932], 'other': [2935], 'myopathies': [2936], '(Eisenberg': [2937], 'particular,': [2942, 3396], 'highly': [2946, 2979], 'mature': [2949, 3134], 'fibres,': [2951, 3135], 'reduced': [2955, 2989], '(two-fold)': [2957], 'human': [2960, 4103, 4788, 4952], 'mouse': [2962, 3598, 4580], 'myoblasts': [2964], '(Cacchiarelli': [2965, 3030], 'study,': [2971], 'despite': [2987], 'muscles:': [2993], '100-fold': [2995, 3064], 'controls,': [3003], '5–10': [3005], 'individuals.': [3012], 'At': [3013], 'variance': [3014], 'doubled': [3024], 'muscles': [3029, 3055], 'its': [3041], 'expression': [3043, 4743, 4909], 'activated': [3045], 'satellite': [3046], 'proliferating': [3049], 'myoblasts,': [3050], 'numerous': [3052], 'where': [3056], 'regeneration': [3058], 'occurs.': [3059], '30-': [3062], 'control,': [3069], 'found,': [3070], 'cannot': [3080], 'simply': [3081], 'reflect': [3082], 'fibres.': [3089], 'Overall,': [3090], 'allowed': [3093, 3424], 'us': [3094, 3425], 'conclude': [3096], 'derive': [3106], 'intensive': [3109], 'occurring': [3111], 'muscles.': [3114, 5278], 'observations': [3119], 'dogs': [3123], '(Cozzi': [3124], '2001),': [3127], 'occurs': [3130], 'miR-206-enriched': [3139], 'immature': [3140], 'determining': [3142], 'when': [3151], 'performances': [3161], 'correlation:': [3171], 'corresponded': [3176], 'low': [3178], 'activity.': [3180], 'quantification': [3183, 3265, 3656, 5149], 'marker': [3188], 'activity,': [3191], 'further': [3203], 'advantage': [3204], 'detection': [3207], 'relates': [3208], 'fact': [3211], 'fresh': [3227], 'preparations,': [3229], 'long': [3238], 'lasting': [3239], 'Our': [3244], 'analyses': [3245, 3800, 3845, 3928, 3946], '(<6': [3252], 'established': [3258], '(NSAA)': [3269], 'available': [3271, 4193, 4263], 'non-ambulating': [3277], 'whose': [3279], 'reaches': [3281], 'lowest': [3283], 'score,': [3284], 'there': [3285], 'indicators': [3287, 3373], 'like': [3288], 'fat': [3291], 'fibrous': [3293], 'deposition': [3295], 'MRI': [3298], '(Kim': [3299], 'Unfortunately,': [3303], 'uniform': [3305], 'functional,': [3306], 'non-invasive': [3307], 'evaluate': [3310], 'available.': [3314], 'future': [3316], 'plan': [3319], 'extend': [3321], 'large': [3326], '‘old’': [3330], 'define': [3335], 'establish': [3339, 3358, 3626], 'reference': [3340], 'testing:': [3343], '(i)': [3344], '(specifically': [3348], 'precursor': [3351], 'cells)': [3353], 'regenerating': [3360], 'potentiality': [3361], '(ii)': [3366], 'residual': [3376], 'mouse.': [3394], '2-month-old': [3398], 'animals,': [3399], '(38': [3407], '23-fold,': [3409], 'respectively)': [3410], 'controls.': [3420], 'exploited': [3434], 'studying': [3438], 'oligonucleotides': [3494], 'Exon': [3504], 'where,': [3512], 'molecules,': [3522], '(this': [3538], 'work': [3539, 4169], 'Denti': [3541, 3575, 3850, 4546, 4594, 4648], 'partial': [3566, 5087], '(<10%;': [3570], '2008)': [3579], 'produce': [3583], 'parameters': [3587], 'reduce': [3590], 'Also': [3596], 'sera,': [3599], 'failed': [3602], 'accurately': [3604], 'collection': [3614], 'will': [3620], 'precise': [3628], 'extent': [3633], 'stage': [3638], '(age,': [3642], 'wheel': [3648], 'chair': [3649], 'use),': [3650], 'studies': [3652], '(dystromiR),': [3660], 'biomarker': [3675, 5181], 'tool': [3676], 'reveal': [3678], 'consideration': [3684], 'test': [3698, 5003], 'applied': [3704], 'measure': [3706], 'effectiveness': [3710], 'seems': [3716], 'particularly': [3717], 'useful': [3718], 'since,': [3719], 'MATERIALS': [3744], 'AND': [3745], 'METHODS': [3746], 'Patient': [3747, 3766], 'inclusion': [3748, 3767], 'criteria': [3749, 3768], 'approved': [3753], 'local': [3756, 4633], 'Ethical': [3757], 'Committee': [3758], 'informative': [3764], 'were:': [3769], 'genetically': [3770], 'proven': [3771], 'diagnosis,': [3775], 'help': [3781], '(only': [3782], 'younger': [3785], '6-years-old),': [3787], 'learning': [3792], 'difficulties': [3793], 'behavioural': [3795], 'problems.': [3796], 'Animal': [3797], '0.5–1': [3809], '×': [3810], '10ˆ12': [3811], 'genome': [3812], 'copies': [3813], 'virus': [3817], 'above': [3837], 'procedures': [3838, 4081], 'H&E': [3840], 'staining': [3841], 'fully': [3847], 'al': [3852, 4322, 4521, 4568, 4616, 4737, 4819, 4903, 4995, 5044, 5247], 'preparation': [3858], 'harvested': [3863], 'centrifugation': [3869], 'tubes.': [3874], 'fmole': [3880], 'cel-lin-2': [3887], '150': [3893], 'µl': [3894, 3898, 3903], '(300': [3897], 'mice).': [3905], 'Small': [3906], 'RNAs': [3907], 'extracted': [3909], 'miRNeasy': [3911], '(Qiagen),': [3912], 'following': [3913], 'manufacturer': [3914], 'specifications': [3915], 'liquid': [3917], 'samples.': [3918], 'miScript': [3923], 'System': [3924], '(Qiagen).': [3925], 'Copy': [3926], 'standard': [3933], 'templates': [3937], 'quantifications': [3941], 'miRNA-spiked.': [3944], 'Statistical': [3945, 3996], 'Each': [3947], 'result': [3955], 'least': [3958, 3965], 'five': [3959, 3966], 'experiments': [3961, 4111], 'group.': [3972], 'Plots': [3974], 'produced': [3976, 4026], 'median': [3978], '(–,': [3979, 3992], 'inside': [3980], 'box)': [3982], 'third': [3985], 'quartiles': [3986], '(box': [3987], 'borders),': [3988], 'minimum': [3989], 'outside': [3993], 'box).': [3995], 'distributions': [4001], 'two-tailed': [4005], 't-test': [4006, 4020], '0.05': [4011, 4067], 'considered': [4013, 4058, 4069], 'significant.': [4014, 4070], 'Welch': [4019], 'applied.': [4022], 'sensitivity': [4029], '1-specificity': [4031], '28': [4033], 'thresholds': [4035], '(Søreide,': [4036], '2009).': [4037], 'Relationship': [4038], 'variables': [4040], 'calculated': [4042], 'coefficient': [4047], '(indicated': [4048], 'R': [4050], 'text).': [4053], '>0.75': [4056], 'acceptable': [4061], 'relationship': [4062], 'contributions': [4072], 'CD': [4073], 'designed': [4074, 4110], 'experiments,': [4075], 'qRT-PCR;': [4083], 'LI': [4084], 'analyses;': [4089, 4098], 'MJ': [4090], 'CV': [4092], 'DA': [4099], 'BE': [4101], 'assessments;': [4108], 'BI': [4109], 'wrote': [4113], 'paper.': [4115], 'Acknowledgements': [4116], 'thank': [4118, 4130], 'Prof.': [4119], 'A.': [4120], 'Musarò': [4121, 4565, 4613, 4663], 'C.': [4123], 'Nicoletti': [4124, 4313, 4557, 4605, 4654], 'facilities.': [4127], 'M.': [4131], 'Cesana': [4132, 4307], 'support,': [4135], 'O.': [4136], 'Sthandier,': [4137], 'T.': [4138, 4141], 'Santini': [4139, 4315], 'Incitti': [4142, 4309, 4650], 'microscopic': [4144], 'Parent': [4147, 4178, 4212], 'Project': [4148, 4179], 'ONLUS': [4149], 'access': [4151], 'Italian': [4154], 'Registry.': [4157], 'DC': [4158], 'recipient': [4161], 'Microsoft': [4164], 'research': [4165], 'PhD': [4166], 'fellowship.': [4167], 'partially': [4171], 'supported': [4172], 'grants': [4174], 'from:': [4175], 'Telethon': [4176], '(GGP07049),': [4177], 'Italia,': [4180], 'EU': [4181, 4229], 'project': [4182], 'SIROCCO': [4183], '(LSHG-CT-2006-037900),': [4184], 'IIT': [4185], '‘SEED’,': [4186], 'PRIN': [4187], 'BEMM.': [4189], 'Supporting': [4190, 4237], 'Medicine': [4197], 'online.': [4198], 'authors': [4200], 'declare': [4201], 'conflict': [4206], 'interest.': [4208], 'association': [4213], 'DMD/BMD': [4215], 'affected': [4216], 'http://parentproject.org': [4219], 'Fund': [4220], 'raising': [4221], 'foundation': [4222], 'rare': [4226], 'http://www.telethon.it': [4228], 'consortium': [4230], 'created': [4231], 'investigate': [4233], 'siRNA/miRNA': [4234], 'functions': [4235], 'http://www.sirocco-project.eu': [4236], 'Detailed': [4239], 'facts': [4240], 'importance': [4242], 'specialist': [4244], 'readers': [4245], 'published': [4247], '”Supporting': [4249], 'Information”.': [4250], 'documents': [4252], 'peer-reviewed,': [4254], 'copy-edited': [4257], 'typeset.': [4259], 'They': [4260], 'made': [4262], 'submitted': [4265], 'authors.': [4268], 'Review_Process_File': [4269], '(269': [4270], 'KB)': [4271], 'suppdata': [4272], '(1.3': [4273], 'MB)': [4274], 'References': [4275], 'Aartsma-Rus': [4276, 5231], 'A,': [4277, 4549, 4566, 4597, 4614, 4662, 4664, 4719, 4763, 4765, 4979, 4983, 5036, 5042, 5232], 'Ommen': [4279], 'GJ': [4280], '(2010)': [4281, 4323, 4482, 4858, 4996, 5111], 'Progress': [4282], 'applications': [4286], 'disorders.': [4289, 4747], 'Eur': [4290], 'J': [4291, 4534, 4707, 4837, 4963, 5183, 5258, 5365], 'Hum': [4292, 4638, 4678], 'Genet': [4293, 4536, 5213, 5280], '18:': [4294], '146-': [4295], '153': [4296], 'CrossrefCASPubMedWeb': [4297, 4347, 4380, 4406, 4474, 4494, 4590, 4644, 4684, 4756, 4794, 4842, 4930, 5063, 5097, 5131, 5165, 5218, 5263, 5284, 5328, 5371], 'Science®Google': [4299, 4349, 4382, 4408, 4457, 4476, 4496, 4544, 4592, 4646, 4686, 4714, 4758, 4796, 4844, 4880, 4932, 4972, 5021, 5065, 5099, 5133, 5167, 5191, 5220, 5265, 5286, 5330, 5373], 'Scholar': [4300, 4350, 4383, 4409, 4458, 4477, 4497, 4545, 4593, 4647, 4687, 4715, 4759, 4797, 4845, 4881, 4933, 4973, 5022, 5066, 5100, 5134, 5168, 5192, 5221, 5266, 5287, 5331, 5374], 'D,': [4302, 4891, 4977, 5142, 5335], 'J,': [4304, 5038], 'Girardi': [4305], 'E,': [4306, 4660, 4897, 4975, 5269, 5290], 'M,': [4308, 4312, 4413, 4560, 4608, 4723, 4805, 4815, 4883, 4895, 4939, 4987, 5234, 5333, 5337], 'T,': [4310, 4316, 4514, 4651, 4849], 'Morlando': [4311], 'C,': [4314, 4558, 4606, 4655, 4725, 4772, 4893, 4935, 5104, 5108, 5344], 'Sthandier': [4317, 4552, 4600, 4652], 'O,': [4318, 4427, 4553, 4562, 4601, 4610, 4653], 'Barberi': [4319], 'L,': [4320, 4508, 4817, 4887, 4989, 4991], 'MicroRNAs': [4324, 4464, 5275], 'involved': [4325], 'circuitries': [4328], 'pathogenesis': [4335], 'controlled': [4337], 'dystrophin/nNOS': [4340], 'pathway.': [4341], 'Cell': [4342, 4469, 4489, 4790], 'Metab': [4343, 4490], '12:': [4344, 4491], '341-': [4345], '351': [4346], 'Chamberlain': [4351], 'JS,': [4352], 'Gibbs': [4353], 'RA,': [4354], 'Ranier': [4355], 'JE,': [4356, 5294], 'Nguyen': [4357], 'PN,': [4358], 'Caskey': [4359], 'CT': [4360], '(1988)': [4361, 4820, 5077], 'Deletion': [4362], 'screening': [4363], 'locus': [4369], 'via': [4370], 'DNA': [4372], 'amplification.': [4373, 5159], 'Nucleic': [4374, 5160], 'Acids': [4375, 5161], 'Res': [4376, 5162], '16:': [4377], '11141-': [4378], '11156': [4379], 'G,': [4385, 4551, 4599, 4985], 'Sampaolesi': [4386], 'M': [4387, 4429, 4462, 4481], '(2007)': [4388, 4738, 5248], 'New': [4389], 'therapies': [4390], 'dystrophy:': [4394, 4864, 4918], 'challenges,': [4395], 'prospects': [4396], 'trials.': [4399], 'Trends': [4400, 5279], '13:': [4403], '520-': [4404], '526': [4405], 'Cozzi': [4410], 'F,': [4411, 4423, 4425, 4761, 4993, 5144], 'Cerletti': [4412], 'Luvoni': [4414], 'GC,': [4415], 'Lombardo': [4416], 'R,': [4417, 4807, 4813, 4943, 5140], 'Brambilla': [4418], 'PG,': [4419], 'Faverzani': [4420], 'S,': [4421, 4516, 4689, 4735, 4889, 4899, 4981, 5072, 5196], 'Blasevich': [4422], 'Cornelio': [4424], 'Pozza': [4426], 'Mora': [4428], '(2001)': [4430], 'Development': [4431], 'pathology': [4434], 'canine': [4436], 'X-linked': [4437], 'dystrophy.': [4439, 4706, 4834, 5013, 5364], 'Quantitative': [4440], 'characterization': [4441], 'histopathological': [4443], 'during': [4445], 'postnatal': [4446], 'skeletal': [4447, 4953], 'development.': [4449], 'Acta': [4450], 'Neuropathol': [4451], '101:': [4452], '469-': [4453], '478': [4454], 'CASPubMedWeb': [4455], 'Crist': [4459, 4478], 'CG,': [4460, 4479], 'Buckingham': [4461, 4480], '(2009)': [4463, 4904, 5171], 'gain': [4465], 'magnitude': [4466], 'muscle.': [4468], 'Cycle': [4470], '8:': [4471, 4927], '3627-': [4472], '3628': [4473], 'Megarole': [4483], '425-': [4492], '426': [4493], 'Dent': [4498], 'KM,': [4499], 'Dunn': [4500], 'DM,': [4501], 'von': [4502], 'Niederhausern': [4503], 'AC,': [4504], 'Aoyagi': [4505], 'AT,': [4506], 'Kerr': [4507], 'Bromberg': [4509], 'MB,': [4510], 'Hart': [4511], 'KJ,': [4512], 'Tuohy': [4513], 'White': [4515], 'den': [4517, 5235], 'Dunnen': [4518, 5236], 'JT,': [4519, 5237], '(2005)': [4522, 4775], 'Improved': [4523], 'dystrophinopathies': [4527], 'unselected': [4530], 'cohort.': [4532], 'Am': [4533], '134:': [4537], '295-': [4538], '298': [4539], 'Wiley': [4540, 4968], 'Online': [4541, 4969], 'LibraryCASPubMedWeb': [4542, 4970], 'MA,': [4547, 4595, 4649], 'Rosa': [4548, 4596, 4762], "D'Antona": [4550, 4598], 'De': [4554, 4602, 4656, 4768], 'Angelis': [4555, 4603, 4657], 'FG,': [4556, 4604, 4658], 'Allocca': [4559, 4607], 'Pansarasa': [4561, 4609], 'Parente': [4563, 4611], 'V,': [4564, 4612, 4767, 4885], '(2006a)': [4569], 'Body-wide': [4570], 'model.': [4581], 'Proc': [4582, 4748, 5055, 5320], 'Natl': [4583, 4749, 5056, 5321], 'Acad': [4584, 4750, 5057, 5322], 'Sci': [4585, 4751, 5058, 5323, 5367], 'USA': [4586, 4752, 5059, 5324], '103:': [4587], '3758-': [4588], '3763': [4589], '(2006b)': [4617], 'Chimeric': [4618], 'virus/antisense': [4620], 'U1': [4621], 'nuclear': [4623], 'effectively': [4625], 'rescues': [4626], 'treatment': [4634], 'Gene': [4639, 4679], 'Ther': [4640, 4680], '17:': [4641], '565-': [4642], '574': [4643], 'Rizzuto': [4659], 'Auricchio': [4661], '(2008)': [4667, 5045], 'Long-term': [4668], 'virus/antisense-mediated': [4672], '19:': [4681], '601-': [4682], '608': [4683], 'Toyokuma': [4690], 'Y,': [4691], 'Momoi': [4692], 'H,': [4693, 5074, 5106], 'Sugita': [4694], 'H': [4695], '(1959)': [4696], 'High': [4697], 'phosphokinase': [4699], 'Biochem': [4708], '46:': [4709], '103-': [4710], '104': [4711], 'CASWeb': [4712], 'Eisenberg': [4716], 'I,': [4717, 4721], 'Eran': [4718], 'Nishino': [4720], 'Moggio': [4722], 'Lamperti': [4724], 'Amato': [4726], 'AA,': [4727, 5226], 'Lidov': [4728], 'HG,': [4729], 'Kang': [4730], 'PB,': [4731], 'KN,': [4733], 'Mitrani-Rosenbaum': [4734], 'Distinctive': [4739], 'patterns': [4740], 'primary': [4745], '104:': [4753], '17016-': [4754], '17021': [4755], 'Fazi': [4760], 'Fatica': [4764], 'Gelmetti': [4766], 'Marchis': [4769], 'ML,': [4770], 'Nervi': [4771], 'minicircuitry': [4777], 'comprised': [4778], 'microRNA-223': [4780], 'transcription': [4782], 'factors': [4783], 'NFI-A': [4784], 'C/EBPalpha': [4786], 'regulates': [4787], 'granulopoiesis.': [4789], '123:': [4791], '819-': [4792], '831': [4793], 'Hoffman': [4798], 'EP,': [4799], 'Fischbeck': [4800], 'KH,': [4801], 'Brown': [4802], 'RH,': [4803, 5298], 'Johnson': [4804], 'Medori': [4806], 'Loike': [4808], 'JD,': [4809], 'Harris': [4810], 'JB,': [4811], 'Waterston': [4812], 'Brooke': [4814], 'Specht': [4816], 'Characterization': [4821], 'muscle-biopsy': [4825], 'specimens': [4826], "Duchenne's": [4830], "Becker's": [4832], 'N': [4835, 5256], 'Engl': [4836, 5257], '318:': [4839], '1363-': [4840], '1368': [4841], 'HK,': [4847], 'Laor': [4848], 'Horn': [4850], 'PS,': [4851, 5024], 'Racadio': [4852], 'JM,': [4853, 5296], 'Wong': [4854], 'B,': [4855, 4941, 4945], 'Dardzinski': [4856], 'BJ': [4857], 'T2': [4859], 'mapping': [4860], 'distribution': [4865], 'assessments.': [4873], 'Radiology': [4874], '255:': [4875], '899-': [4876], '908': [4877], 'CrossrefPubMedWeb': [4878, 5019, 5189], 'Kinali': [4882], 'Arechavala-Gomeza': [4884], 'Feng': [4886], 'Cirak': [4888], 'Hunt': [4890], 'Adkin': [4892], 'Guglieri': [4894], 'Ashton': [4896], 'Abbs': [4898], 'Nihoyannopoulos': [4900], 'P,': [4901, 4937], 'Local': [4905, 5249], 'restoration': [4906, 5251], 'morpholino': [4912], 'oligomer': [4913], 'AVI-4658': [4914], 'single-blind,': [4920], 'placebo-controlled,': [4921], 'dose-escalation,': [4922], 'proof-of-concept': [4923], 'study.': [4924], 'Lancet': [4925], 'Neurol': [4926, 5366], '918-': [4928], '928': [4929], 'Malm': [4934], 'Nyberg': [4936], 'Engstrom': [4938], 'Sjodin': [4940], 'Lenkei': [4942], 'Ekblom': [4944], 'Lundberg': [4946], '(2000)': [4948], 'Immunological': [4949], 'changes': [4950], 'after': [4957, 5309], 'eccentric': [4958], 'exercise': [4959], 'multiple': [4961], 'biopsies.': [4962], 'Physiol': [4964], '529:': [4965], '243-': [4966], '262': [4967], 'Martinelli': [4976], 'Berardinelli': [4978], 'Messina': [4980], 'Vasco': [4984], 'Main': [4986], 'Doglio': [4988], 'Politano': [4990], 'Cavallaro': [4992], 'Assessment,': [5000], '6-minute': [5001], 'walk': [5002], 'timed': [5005], 'items': [5006], 'Neuromuscul': [5014], 'Disord': [5015], '20:': [5016], '712-': [5017], '716': [5018], 'Mitchell': [5023], 'Parkin': [5025], 'RK,': [5026], 'Kroh': [5027], 'EM,': [5028], 'Fritz': [5029], 'BR,': [5030], 'Wyman': [5031], 'SK,': [5032], 'Pogosova-Agadjanyan': [5033], 'EL,': [5034], 'Peterson': [5035], 'Noteboom': [5037], "O'Briant": [5039], 'KC,': [5040], 'Allen': [5041], 'Circulating': [5046], 'microRNAs': [5047, 5113, 5308], 'stable': [5049], 'blood-based': [5050], 'detection.': [5054], '105:': [5060, 5325], '10513-': [5061], '10518': [5062], 'Monaco': [5067], 'AP,': [5068], 'Bertelson': [5069], 'CJ,': [5070, 5138], 'Liechti-Gallati': [5071], 'Moser': [5073], 'Kunkel': [5075], 'LM': [5076], 'An': [5078], 'explanation': [5079], 'phenotypic': [5082], 'bearing': [5086], 'locus.': [5092], 'Genomics': [5093], '2:': [5094], '90-': [5095], '95': [5096], 'Schöler': [5101], 'N,': [5102, 5198, 5271], 'Langer': [5103], 'Döhner': [5105], 'Buske': [5107], 'Kuchenbauer': [5109], 'F': [5110], 'novel': [5116], 'class': [5117], 'biomarkers:': [5119], 'comprehensive': [5121, 5204], 'review': [5122], 'literature.': [5125], 'Exp': [5126], 'Hematol': [5127], '38:': [5128], '1126-': [5129], '1130': [5130], 'Schouten': [5135], 'JP,': [5136], 'McElgunn': [5137], 'Waaijer': [5139], 'Zwijnenburg': [5141], 'Diepvens': [5143], 'Pals': [5145], 'G': [5146], '(2002)': [5147], 'Relative': [5148], '40': [5151], 'nucleic': [5152], 'acid': [5153], 'sequences': [5154], '30:': [5163], '57': [5164], 'Søreide': [5169], 'K': [5170], 'Receiver-operating': [5172], 'characteristic': [5173], 'diagnostic,': [5177], 'prognostic': [5178], 'predictive': [5180], 'research.': [5182], 'Clin': [5184], 'Pathol': [5185], '62:': [5186], 'Stockley': [5193], 'TL,': [5194], 'Akber': [5195], 'Bulgin': [5197], 'Ray': [5199], 'PN': [5200], '(2006)': [5201], 'Strategy': [5202], 'testing': [5206], 'dystrophies.': [5212], 'Test': [5214], '10:': [5215], '229-': [5216], '243': [5217], 'JC,': [5224], 'Janson': [5225], 'Ginjaar': [5227], 'IB,': [5228], 'Frankhuizen': [5229], 'WS,': [5230, 5300], 'Bremmer-Bout': [5233], 'Koop': [5238], 'K,': [5239], 'der': [5241], 'Kooi': [5242], 'AJ,': [5243], 'Goemans': [5244], 'NM,': [5245], 'oligonucleotide': [5254], 'PRO051.': [5255], '357:': [5260], '2677-': [5261], '2686': [5262], 'Liu': [5270], 'Olson': [5272, 5303], 'EN': [5273, 5304], '(2008a)': [5274], 'flex': [5276], '24:': [5281], '159-': [5282], '166': [5283], 'Sutherland': [5291], 'LB,': [5292], 'Thatcher': [5293], 'DiMaio': [5295], 'Naseem': [5297], 'Marshall': [5299], 'Hill': [5301], 'JA,': [5302], '(2008b)': [5305], 'Dysregulation': [5306], 'miR-29': [5316], 'cardiac': [5318], 'fibrosis.': [5319], '13027-': [5326], '13032': [5327], 'Zatz': [5332], 'Rapaport': [5334], 'Vainzof': [5336], 'Passos-Bueno': [5338], 'MR,': [5339], 'Bortolini': [5340], 'ER,': [5341], 'Pavanello': [5342], 'Rde': [5343], 'Peres': [5345], 'CA': [5346], '(1991)': [5347], 'creatine-kinase': [5349], 'pyruvate-kinase': [5352], '(PK)': [5353], 'activities': [5354], 'compared': [5359], '102:': [5368], '190-': [5369], '196': [5370], 'Previous': [5375], 'ArticleNext': [5376], 'Article': [5377], 'Volume': [5378], '3Issue': [5379], '51': [5380], 'May': [5381], '2011In': [5382], 'issue': [5384], 'FiguresReferencesRelatedDetailsLoading': [5385], '...': [5386]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2141619720', 'counts_by_year': [{'year': 2024, 'cited_by_count': 11}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 23}, {'year': 2020, 'cited_by_count': 25}, {'year': 2019, 'cited_by_count': 17}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 21}, {'year': 2016, 'cited_by_count': 28}, {'year': 2015, 'cited_by_count': 23}, {'year': 2014, 'cited_by_count': 25}, {'year': 2013, 'cited_by_count': 17}, {'year': 2012, 'cited_by_count': 18}], 'updated_date': '2024-12-16T11:38:19.974918', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
