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877, 1044, 1161, 1337, 1430, 1443, 1710, 1734, 1808, 2911, 3838, 3938, 3953, 3973], '(IR)': [596, 909, 4098], 'has': [597, 603, 892, 953, 1322, 1385, 1418], 'been': [598, 605, 893, 954, 1029, 1263, 1323, 1406, 1419, 1931, 3799], 'recently': [599], 'reported.': [600], 'However,': [601, 1453], 'causality': [602], 'not': [604, 916, 1087, 1405, 1609, 1623, 1958, 2625, 2931, 3177, 3299, 3344, 3378, 3511, 3812], 'established.': [606], 'The': [607, 719, 1035, 1191, 1706, 1725, 1763, 2381, 2421, 2485, 2523, 2760, 2788, 2875, 2974, 3294, 3846, 4268], 'cross-sectional': [608, 1380, 3806], 'nature': [609, 1381], 'most': [611, 2571], 'reported': [612, 1360, 2945], 'studies': [613, 1384, 1403], 'varying': [615], 'degrees': [616, 1506], 'fibrosis': [618, 1084, 1118, 1122, 1158, 1333, 1342, 2622, 3004, 3020], 'limited': [620, 1469], 'definitive': [621, 1454], 'conclusions': [622, 1455], 'about': [623, 1456], 'independent': [625, 950, 1017, 1113, 1296, 1458], 'role': [626, 1055, 1137, 1238, 1392, 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1575], '(LT)': [650, 1481], 'recipients.': [651], 'A': [652, 1433, 1594, 2560, 2983, 3273, 3307], 'total': [653, 1595, 2152, 2948, 2984, 3274, 3308], '34': [655, 1644], 'adults': [656], '(14': [657], 'HCV(+)': [658, 733, 754, 795, 820, 1726, 1740, 1962, 2803, 2864, 2977, 3040, 3216, 3277, 3366, 3406, 3425, 3442, 3474, 3583, 3750, 3870, 3913, 4029, 4039, 4061, 4069], '20': [660, 1768], 'HCV(−))': [661], 'who': [662, 1580, 1776, 1997, 2778], 'underwent': [663, 1581, 1599, 2639, 2990], 'consecutive': [664, 1574], 'LT': [665, 1583, 1600, 1659, 2925], 'were': [666, 692, 695, 797, 847, 1608, 1620, 1646, 1652, 1671, 1694, 1864, 1882, 1913, 1998, 2039, 2049, 2057, 2068, 2089, 2115, 2157, 2165, 2175, 2186, 2396, 2407, 2415, 2424, 2479, 2509, 2551, 2556, 2582, 2611, 2614, 2624, 2644, 2678, 2779, 2784, 2853, 2883, 2886, 2912, 2957, 3181, 3279, 3298, 3315, 3328, 3390, 3733, 3839, 3894, 4013, 4312], 'followed': [667, 1010, 1483, 1653], 'during': [668, 756, 822, 1514, 1601, 2467, 2764, 2968, 3267, 3289, 3361, 4043, 4073], 'first': [670, 758, 792, 824, 1516, 3291, 3857, 4045, 4075], 'year': [671, 759, 825, 1517, 1662, 4046], 'posttransplantation.': [672], 'was': [674, 727, 747, 750, 1015, 1711, 1839, 1871, 1897, 1957, 1991, 2128, 2144, 2246, 2268, 2300, 2323, 2334, 2348, 2370, 2388, 2530, 2563, 2713, 2736, 2754, 2768, 2797, 2811, 2936, 3207, 3241, 3347, 3523, 3552, 3739, 3768, 3787, 3811, 3856, 3860, 3927, 3954, 3974, 3993, 4032, 4064, 4164, 4273, 4351], 'estimated': [675, 2371, 2510], 'using': [676, 1104, 1901, 2130, 2167, 2177, 2197, 2248, 2270, 2325, 2409, 2417, 2481, 2553, 2558, 2715, 3897, 4011, 4271], 'homeostasis': [678, 1547, 2272], 'model': [679, 1492, 1548, 1552, 2273, 2278, 2309, 2562, 2581, 2630, 3794, 3962], 'assessment': [680, 2274], '(HOMA).': [681], 'Univariate': [682], 'multivariate': [684, 1105], 'repeated': [685, 2517, 2557], 'measures': [686], 'analyses': [687, 2550], 'Cox': [689, 2642, 2733], 'regression': [690, 2483, 2734, 2810, 3793], 'models': [691, 2513, 2643], 'used.': [693, 2603], 'There': [694, 726, 2852, 2885, 2935, 2956, 3206, 3240, 3327, 3346, 3551, 3738, 3859, 4031, 4063], 'no': [696, 722, 736, 2867, 2887, 2937, 2958, 3242, 3329, 3348, 3416, 3467, 3521, 3553], 'significant': [697, 928, 1633, 2597, 2869, 2888, 3243, 3417, 3468, 3555, 4258], 'differences': [698, 832, 2889], 'groups': [701, 746, 2827, 2882, 2893, 2929, 3253, 3353, 3428, 3477, 3560], 'respect': [703, 2895, 3355], 'age,': [705, 1860, 2430], 'body': [706, 1559], 'mass': [707, 1560, 2331], 'index': [708, 2332], '(BMI),': [709], 'family': [710, 2432, 2940], 'history': [711, 1670, 1743, 1867, 1893, 2433, 2941, 2946, 3117], 'diabetes,': [713, 921, 2435], 'alcohol': [714, 837, 1745, 1895, 2346, 2353, 2436, 2950], 'consumption,': [715, 838, 2437], 'or': [716, 723, 839, 1578, 1950, 2005, 2017, 2703, 2777, 2817, 2944, 3008, 3333, 3337, 4329], 'laboratory': [717, 3536], 'indices.': [718], 'had': [721, 1632, 1777, 2217, 2257, 2979, 3003, 3018, 3798], 'minimal': [724, 3382], 'fibrosis.': [725, 842, 1534], 'lower': [728, 784, 2002, 2219, 2259, 3211, 3402, 3437, 3906, 4066, 4175], 'prednisone': [729, 2473, 3184, 3194, 3212, 3228, 3403, 3422, 3438], 'use': [730, 740, 1982, 2440, 2474, 2488, 3213, 3247, 3260, 3332, 3404, 3439, 3453], 'group,': [734, 2865, 3222], 'difference': [737, 2870, 2919, 2938, 3244, 3349, 3418, 3469, 3556], 'tacrolimus': [742, 3197, 3249, 3455, 3471], 'two': [745, 2873, 2892, 2928, 2954, 3252, 3559], 'found.': [748], '77%': [751, 3978, 4107], 'higher': [752, 816, 2319, 2743, 2905, 3743, 3864, 4024, 4036, 4142], 'subjects': [755, 796, 1503, 1607, 1645, 1730, 1769, 2317, 2741, 2959, 3278, 3297, 3314, 3385, 3755, 4042, 4072, 4173, 4204], 'post-LT': [760, 1924, 3542, 4047, 4077, 4156, 4344], 'when': [761, 3771, 3896, 3944, 4048, 4189], 'controlling': [762, 2831, 3772], 'BMI': [764, 2753, 2899, 3090, 3774, 3824, 3835, 3907, 3926, 3992, 4059, 4067, 4113, 4262], '(P': [765, 787, 808, 3237, 3444, 3480, 3920, 3984, 4003, 4078, 4186, 4263, 4275], '=': [766, 788, 1749, 1754, 1761, 1798, 1803, 1810, 1815, 1821, 1828, 1833, 2289, 2355, 3038, 3042, 3107, 3112, 3122, 3127, 3238, 3377, 3445, 3481, 3579, 3585, 3757, 3761, 3764, 3776, 3780, 3783, 3876, 3880, 3883, 3985, 4004, 4187, 4264, 4276], '0.035).': [767], 'Subjects': [768, 1651, 1996, 2770, 4140], 'high': [770, 777, 2653, 2704, 2731, 2749, 3700, 3969, 4162, 4167, 4206, 4214, 4236, 4330, 4349], 'ribonucleic': [772, 1528, 1563], 'acid': [773, 1529], '(RNA)': [774, 1530], 'levels': [775, 846, 1525, 1971, 2156, 2164, 2174, 2185, 2677, 2747, 2751, 3472, 3817, 3908, 4147, 4169, 4195, 4210, 4226, 4249], 'reached': [776, 2748, 4166, 4213, 4235], 'HOMA-IR': [778, 2554, 2663, 3340, 3853, 3865, 4025, 4037, 4163, 4215, 4285], 'significantly': [779, 815, 2572, 3742, 3813, 3840, 4170], 'earlier': [780, 850, 4171, 4218, 4241], 'than': [781, 805, 993, 1511, 2013, 2022, 2036, 3010, 3871, 4040, 4070, 4172, 4219, 4242], 'those': [782, 1350, 2006, 2609, 4220, 4243], 'RNA': [786, 845, 1723, 1775, 1970, 2087, 2184, 2196, 2237, 2241, 2676, 2720, 2746, 3320, 4130, 4146, 4177, 4194, 4209, 4225, 4248, 4291, 4305, 4310], '0.03).': [789], 'Following': [790], 'month': [793, 2097, 2793, 2837, 3323, 4154, 4343], 'post-LT,': [794], '4': [798], 'times': [799, 4217, 4240], 'likely': [801, 1305, 1346, 1373], 'become': [803], 'diabetic': [804, 2834, 2914], 'HCV(−)': [806, 1764, 2805, 2858, 3036, 3221, 3370, 3427, 3476, 3754, 3873, 3918, 4041, 4071], 'controls': [807, 1513], '<': [809, 3921, 4079], '0.01).': [810, 4080], 'In': [811, 996, 1062, 1953, 2297, 2807, 3722, 3941, 4201], 'conclusion,': [812], 'there': [813, 3414, 3465], 'is': [814, 878, 900, 915, 923, 931, 1045, 1086, 1167, 1178, 1200, 1204, 1282, 2307, 3415, 3466], 'group': [821, 1727, 1741, 1765, 1786, 1963, 2859, 2967, 3203, 3217, 3233, 3443, 3874, 3919], 'post-LT.': [826, 1663, 2839, 3027, 3293], 'This': [827, 898, 1272, 1785, 2215, 2255, 2306, 3766, 4254], 'cannot': [828], 'be': [829, 1111, 1329, 1468, 2595, 3930], 'explained': [830], 'BMI,': [834, 1558, 2431, 2588, 3948, 3967], 'medications': [835, 1912, 1990, 2000, 2602, 2783], 'used,': [836], 'degree': [840, 1116], 'Higher': [843, 4128], 'associated': [848, 894, 926, 955, 1205, 1265, 1331, 3814, 3827, 3841, 3956, 3975, 3994, 4105], 'elevations': [851], 'HOMA-IR.': [853], 'Collectively,': [854], 'these': [855, 1383, 4232], 'results': [856, 3534, 3886, 3893], 'provide': [857], 'strong': [858], 'evidence': [859, 1133, 1147], 'that': [860, 1077, 1150, 1306, 1370, 1501, 1520, 1553, 2310, 2569, 2610, 3520, 3796, 4348], 'Transpl,': [868], '2007.': [869], '©': [870], '2007': [871], 'AASLD.': [872], 'Hepatitis': [873, 2181], 'major': [880, 933, 1421], 'public': [881], 'health': [882, 984], 'concern,': [883], 'infecting': [884], '3.3%': [885], "world's": [888], 'population.': [889, 1319], 'Recently,': [890], 'diabetes': [896, 1009, 1445, 1869, 2763, 2791, 2820, 2923, 2943, 3172], 'mellitus.1': [897], 'based': [901, 2058, 2069, 2403, 2538], 'on': [902, 2034, 2059, 2070, 2404, 2519, 2539, 3012, 4096], 'finding': [904], 'increased': [906, 967, 976, 1208, 1968, 3958], 'among': [910, 1003, 4060], 'HCV-infected': [911, 1095, 1102, 1269, 1318, 1502], 'subjects.2,': [912], '3': [913, 1618, 1639, 2102, 3023, 3076, 3531], 'only': [917, 2632, 3834], 'precursor': [919], 'but': [922, 1378, 2691, 3000], 'also': [924, 1028, 1148, 2301, 2755], 'itself': [925, 1321], 'morbidity.4': [929], 'component': [934], 'nonalcoholic': [936, 1198, 1256, 1277, 1353], 'fatty': [937, 1215, 1278, 1354], 'disease': [939, 1176, 1759, 1792], 'other': [941, 1250, 1778, 3295, 3942, 4202], 'conditions': [942], 'such': [943], 'as': [944, 1275, 1489, 2209, 2336, 2350, 2398, 2494, 2496, 2532, 2606, 2656, 2666, 2680, 2786, 3751, 3899, 3914, 4149, 4196, 4286, 4314, 4335], 'polycystic': [945], 'ovarian': [946], 'syndrome.5': [947], 'Insulin': [948, 3662, 4086], 'resistance,': [949], 'dysglycemia,': [952], '2-fold': [958], 'increase': [959, 3981, 3990, 4000, 4108], 'risk': [962, 968, 977, 1253], 'hypertension,': [964], '3-fold': [966], 'coronary': [970], 'heart': [971], 'disease,': [972, 1280], 'an': [974, 1016, 1112, 1207, 1902, 2118, 2227, 2708, 3988], '8-fold': [975], 'type': [979, 1007], 'diabetes.': [981], 'These': [982, 3885], 'undesirable': [983], 'effects': [985], 'can': [986], 'develop': [987, 1504], 'period': [990, 2108, 2365, 2478, 2767, 3364], 'less': [992, 3009], '15': [994], 'years.6': [995], 'Bonora': [1000], 'et': [1001, 1065, 1074, 1098, 1367, 1936, 2064, 2076], 'al.,7': [1002], '1,326': [1004], 'individuals': [1005, 1103], '4.5': [1012], 'years,': [1013], 'predictor': [1018, 1114, 2598], 'cardiovascular': [1020], 'disease.': [1021, 1061, 1498], 'Furthermore,': [1022, 1146], 'fasting': [1023, 2151, 2290, 2294, 2453, 2456, 2772, 3729, 3744, 3829], 'hyperinsulinemia8': [1024], 'shown': [1030], 'predict': [1032], 'overall': [1033], 'mortality.9': [1034], 'presence': [1036, 2584, 3950], 'setting': [1041], 'particular': [1047], 'importance': [1048], 'because': [1049, 1964, 2631, 3301], 'hyperinsulinemia': [1050, 1078, 1139, 1307], 'appears': [1051], 'play': [1053, 1236], 'progression': [1058, 1334], 'HCV-liver': [1060], '2003,': [1063], 'Hickman': [1064, 1073], 'al.10': [1066, 1075], 'evaluated': [1067, 1100, 2461, 3734, 4049], '160': [1068], 'patients': [1069, 1187, 1576, 1598, 1619, 1626, 1788, 1843, 2633, 2908, 2978, 3367, 3371], 'chronic': [1071, 1174, 1291, 3231], 'HCV.': [1072], 'concluded': [1076], 'contributes': [1079, 1308], 'merely': [1088], 'consequence': [1090], 'injury': [1093], 'individuals.': [1096, 2522], 'al.3': [1099, 1368], '260': [1101], 'analysis': [1106, 2735, 3409, 3460, 4010], 'found': [1108, 2593, 3905, 4180], 'rate': [1120, 2818, 3358], 'progression.': [1123], 'Recent': [1124], 'investigations': [1125], 'at': [1126, 1584, 1673, 1678, 1696, 1884, 1915, 1926, 1941, 2091, 2792, 2836, 2900, 3024, 3032, 3234, 3286, 3322, 3526, 3539, 3570, 4160], 'cellular': [1128], 'level': [1129, 1531, 2591, 2658, 2774, 3198, 3746, 3810], 'provided': [1131, 1844, 3525], 'additional': [1132], 'direct': [1136], 'fibrosis.11,': [1144], '12': [1145, 1684, 1702, 3276, 3324], 'suggests': [1149, 1273, 3433], 'may': [1152, 1235], 'contribute': [1153], 'indirectly': [1162], 'through': [1163, 2511], 'steatosis.': [1164], 'Hepatic': [1165], 'steatosis': [1166, 1196, 1267, 1289, 1313, 1345], 'considered': [1168, 2040, 2578, 2756, 2913, 3316], 'common': [1170], 'histological': [1171], 'feature': [1172], 'present': [1179], 'up': [1181], '30%': [1183], '70%': [1185], 'infection.13': [1190], 'steatohepatitis': [1199, 1257], 'well': [1201, 2495], 'established.14': [1202], 'flux': [1209], 'dietary': [1211], 'stored': [1213], 'free': [1214], 'acids': [1216], 'away': [1217], 'from': [1218, 1655, 1873, 1993, 2280, 2722, 4153, 4341], 'adipose': [1219], 'tissue': [1220], 'into': [1222, 2627], 'liver,': [1224], 'leading': [1225], 'hepatic': [1230], 'steatosis.15': [1231], 'Although': [1232, 2902], 'viral': [1233, 2183], 'factors': [1234, 1254, 2568], 'steatosis,': [1243], 'specifically': [1244], 'genotype': [1246, 3141], '3a': [1247], 'infection,16,': [1248], '17': [1249], 'elements,': [1251], 'including': [1252, 1665, 1858, 1878, 2082], 'abdominal': [1259], 'fat': [1260], 'mass,': [1261], 'independently': [1264, 1414, 1532, 3955], 'subjects.18,': [1270], '19': [1271], 'that,': [1274], 'important': [1283], 'pathogenesis': [1286], 'obesity-related': [1288], 'infection.20': [1293], 'Given': [1294], 'it': [1302], 'is,': [1303], 'therefore,': [1304], 'even': [1314, 3769], 'nonobese': [1317], 'Steatosis': [1320, 2066, 2620], 'noted': [1324, 1737, 3928], 'multiple': [1326, 3792], 'investigators': [1327], 'strongly': [1330, 3826], 'mechanisms': [1340], 'HCV-associated': [1344], 'similarities': [1348], 'involved': [1351], 'disease.17,': [1356], '19-21': [1357], 'Results': [1358, 4008], 'previously': [1359, 1907, 1933], 'group2': [1363], 'suggest': [1369], 'increasing': [1371], 'viremia': [1372, 1413], 'leads': [1374], 'greater': [1376, 1505, 2012, 2021], 'IR,': [1377, 1540, 2314], 'thus': [1386], 'far': [1387], 'precluded': [1388], 'establishing': [1389], 'Most': [1400], 'importantly,': [1401], 'previous': [1402], 'able': [1407], 'clearly': [1409], 'changes': [1411], 'histology,': [1416], 'which': [1417, 4161], 'impediment': [1422], 'clarifying': [1424], 'number': [1434, 2356, 3383], 'reports': [1436], 'discussed': [1438], 'and/or': [1446], 'over': [1448, 1509, 2475, 2507, 2821, 3199, 3254, 3341, 3429, 3457, 3478, 3731, 3747, 3818, 3844, 3854, 3866, 3909, 4026], 'past': [1450], 'few': [1451], 'years.': [1452], 'continue': [1466], 'confounding': [1471], 'factors.': [1472], 'Therefore,': [1473], 'we': [1474, 2460, 3945], 'selected': [1475, 3801], 'immediately': [1484], 'after': [1485, 1641, 2117, 2795, 4259], 'transplantation': [1486, 2105, 2796], 'serve': [1488], 'plausible': [1491], 'de': [1494], 'novo': [1495], 'hypothesized': [1500], 'time': [1510, 1657, 1674, 1886, 1917, 2094, 2508, 2529, 2649, 2725, 2822, 3200, 3342, 3479, 3543, 3732, 3748, 3819, 3855, 3867, 3910, 4027, 4159, 4347], 'uninfected': [1512], 'posttransplantation,': [1518], 'would': [1522], 'correlate': [1523], 'Abbreviations': [1535], 'HCV,': [1536, 3966], 'virus;': [1539], 'resistance;': [1542], 'LT,': [1543], 'transplant(ation);': [1545], 'HOMA,': [1546, 3833], 'assessment;': [1549], 'HOMA2,': [1550], 'HOMA': [1551, 2503, 2527, 2654, 2750, 3676, 4168, 4237, 4350], 'accurately': [1555, 2312], 'reflects': [1556, 2313], 'IR;': [1557], 'index;': [1561], 'RNA,': [1562], 'acid.': [1564], 'PATIENTS': [1565], 'AND': [1566], 'METHODS': [1567], 'Patient': [1568, 1853, 2841], 'Population': [1569], 'Our': [1570, 3960], 'consisted': [1572, 1766], '(18-year-old': [1577], 'older)': [1579], 'orthotopic': [1582], '2002': [1590], 'March': [1592], '2003.': [1593], '49': [1597], 'period.': [1603, 2470], 'Of': [1604], 'these,': [1605, 2998], '8': [1606, 2123], 'eligible': [1610], 'participate': [1612], '(pediatric': [1616], 'patients),': [1617], 'missed': [1621], 'enrolled,': [1624], 'refused': [1627], 'participate,': [1629], 'complications': [1634], 'postoperatively': [1635], 'died': [1637], 'within': [1638], 'months': [1640, 1685, 1703, 2103, 3026], 'transplantation.': [1642, 1687, 1705, 1784, 2901], 'Thus,': [1643], 'included': [1647, 1728, 1742, 1787, 1945, 3963], 'study.': [1650, 1852, 2973, 3272, 3550], 'longitudinally': [1654], 'until': [1660, 2729, 4345], '1': [1661, 2037, 2110, 3001, 3011, 3065, 3067, 3074, 3149, 3188, 3546, 4155, 4342], 'Data': [1664], 'patient': [1666, 1874, 3002, 3017], 'characteristics': [1667, 1857, 2541, 2846], 'medical': [1669], 'obtained': [1672, 1695, 1840, 1872, 1883, 1992, 2045, 2090, 2158, 2714, 3538, 3895], 'transplantation,': [1676, 2917], '1,': [1679, 1697], '3,': [1680, 1698], '6,': [1681, 1699], '9,': [1682, 1700], 'following': [1686, 1704, 2104, 2286, 2422], 'Anthropometric': [1688, 1876], 'measurements': [1689], 'blood': [1691, 1888, 2003, 2010, 2019, 2113], 'sample': [1692, 1889], 'collections': [1693], 'diagnosis': [1707], 'established': [1712], 'serological': [1714], 'markers': [1715], 'confirmed': [1717, 1732], 'all': [1719, 1842, 2083, 2304, 2391, 2462, 2988, 2999], 'cases': [1720], 'testing.': [1724], '14': [1729, 3056, 3313], 'pretransplantation.': [1735], 'Comorbidities': [1736], 'abuse': [1746], 'pretransplantation': [1747], '(n': [1748, 1753, 1760, 1797, 1802, 1809, 1814, 1820, 1827, 1832, 3037, 3041, 3578, 3584], '7),': [1750], 'hepatocellular': [1751, 1800], 'carcinoma': [1752, 1801], '3),': [1755], 'sickle': [1757], 'cell': [1758], '1).': [1762, 1834], 'negative': [1771], 'tests': [1772, 2638], 'causes': [1779], 'failure': [1782], 'necessitating': [1783], 'end-stage': [1790], 'caused': [1793], 'alcoholic': [1795], 'cirrhosis': [1796, 1813, 1819], '10),': [1799], '5),': [1804], 'B': [1806], '2),': [1811], 'cryptogenic': [1812], '4),': [1816], 'primary': [1817, 2534], 'biliary': [1818], '1),': [1822, 1829], 'vasoactive': [1823], 'intestinal': [1824], 'peptide-producing': [1825], 'tumor': [1826], 'hemochromatosis': [1831], 'Institutional': [1835], 'board': [1837], 'approval': [1838], 'written': [1845], 'informed': [1846], 'consent': [1847], 'participation': [1849], 'Characteristics': [1854, 2842, 3031], "Patients'": [1855, 2843], 'demographic': [1856], 'gender,': [1859, 2428], 'self-reported': [1862], 'ethnicity': [1863], 'reviewed.': [1865], 'Family': [1866, 3116], 'mellitus': [1870], 'interviews.': [1875], 'data': [1877, 3432], 'weight': [1879, 2337], 'height': [1881, 2341], 'collection.': [1890], 'Total': [1891, 2344, 3605], 'lifetime': [1892, 2345, 2352, 2949], 'consumption': [1896, 2347, 2354, 2951], 'assessed': [1898, 2187], 'interview': [1900], 'abbreviated': [1903], 'validated': [1908, 2277], 'questionnaire.22,': [1909], '23': [1910, 2378, 3595], 'Immunosuppressive': [1911, 1921], 'recorded': [1914], 'each': [1916, 2673, 2824, 3202], 'point': [1918, 2726, 3288, 3544], 'interest.': [1920, 3205], 'regimens': [1922, 1940], 'described': [1932, 2073], 'Baid': [1935], 'al.24': [1937], 'Maintenance': [1938], 'immunosuppressive': [1939], 'prednisone,': [1946], 'tacrolimus,': [1947], 'azathioprine,': [1949], 'mycophenolate': [1951, 1955], 'mofetil.': [1952], 'general,': [1954], 'mofetil': [1956], 'used': [1959, 2389, 2531, 2564, 2645, 2737, 2812], 'concerns': [1966], 'regarding': [1967, 1980], 'potential': [1973], 'early': [1975], 'graft': [1976], 'recurrence.25,': [1977], '26': [1978], 'Information': [1979], "participants'": [1981], 'glucose-lowering': [1984], 'agents,': [1985], 'antihypertensive': [1986, 3393], 'drugs,': [1987], 'lipid-lowering': [1989], "patients'": [1994], 'charts.': [1995], 'taking': [1999], 'pressure': [2004, 2011, 2020], 'systolic': [2009], '140': [2014], 'mm': [2015, 2024], 'Hg': [2016, 2025], 'diastolic': [2018], '90': [2023], '(stage': [2026], 'I': [2027], 'classification': [2028], 'Joint': [2031], 'National': [2032], 'Committee)': [2033], 'occasion': [2038], 'hypertensive.': [2041], 'Allograft': [2042], 'biopsies': [2044, 2465, 2992], 'clinical': [2047], 'purposes': [2048], 'reviewed': [2050], 'blinded': [2053], 'pathologist.': [2054], 'Fibrosis': [2055], 'scores': [2056, 2067, 2623, 3005], 'scale': [2061, 2072], 'Ishak': [2063, 3014], 'al.27': [2065], 'Brunt': [2075], 'al.28': [2077], 'Laboratory': [2078, 2080], 'Determinations': [2079], 'data,': [2081], 'chemistries': [2084, 3565], 'levels,': [2088, 2449], '5': [2092, 2854, 2986, 3113, 3310], 'different': [2093], 'points': [2095], '(1': [2096], 'posttransplant,': [2098], 'then': [2100], 'every': [2101], 'yr).': [2111], 'Venous': [2112], 'samples': [2114, 2234], 'collected': [2116], 'overnight': [2119], 'fast': [2120], '(minimum': [2121], 'hours).': [2124], 'Plasma': [2125], 'glucose': [2126, 2295, 2773], 'concentration': [2127], 'measured': [2129, 2145, 2166], 'Hitachi': [2132], '917': [2133], '(Hitachi,': [2134], 'Yokohama,': [2135], 'Japan)': [2136], 'Roche': [2137, 2198, 2249], 'reagent': [2138], 'hexokinase': [2139], 'method.': [2140], 'Fasting': [2141], 'plasma': [2142], 'radioimmunoassay.': [2147], 'Serum': [2148], 'aminotransferase,': [2149], 'bilirubin,': [2150], 'cholesterol,': [2153], 'triglyceride': [2155], 'standard': [2160, 3759, 3778, 3878, 4123], 'assays.': [2161], 'High-density': [2162, 3785, 3808], 'lipoprotein': [2163, 2173, 2590, 3786, 3809], 'polyethylene': [2168], 'glycol-modified': [2169], 'enzymes,': [2170, 2447], 'low-density': [2172], 'calculated': [2176, 2269, 2302, 2324, 2335, 2349, 2798], 'Friedewald': [2179], 'formula.': [2180], 'reverse-transcription': [2189], 'polymerase': [2190, 2243], 'chain': [2191, 2244], 'reaction': [2192, 2245], 'detection': [2193, 2222, 2262], 'COBAS': [2199], 'Amplicor': [2200, 2250], '2.0': [2201, 2251], '(Roche': [2202, 2252], 'Molecular': [2203, 2253], 'Diagnostics,': [2204], 'Branchburg,': [2205], 'NJ)': [2206], 'expressed': [2208, 2283, 2397], 'International': [2210], 'Units': [2211], 'per': [2212, 2711], 'milliliter': [2213], '(IU/mL).': [2214], 'assay': [2216, 2256], 'limit': [2220, 2229, 2260], '600': [2224], 'IU/mL': [2225, 2683, 2699, 4317, 4325], 'upper': [2228], '850,000': [2231], 'IU/mL.': [2232, 2265], 'For': [2233, 2672], '<600': [2238, 4252, 4319], 'IU/mL,': [2239, 2686, 4320], 'qualitative': [2242, 2694], 'performed': [2247, 2466, 2552], 'Diagnostics).': [2254], '60': [2264], 'Calculations': [2266], '(HOMA),': [2275], 'derived': [2279], 'normal': [2281], 'volunteers,': [2282], 'equation:': [2287], '(mU/L)': [2292], '×': [2293, 2359, 2364], '(mmol/L)/22.5.29': [2296], 'addition,': [2298, 2808], 'HOMA2-IR': [2299, 2322, 3898, 4012, 4272], 'patients.': [2305], 'particularly': [2315], 'levels.': [2321, 2458, 4178], 'publicly': [2327], 'available': [2328, 2463], 'program.30': [2329], 'Body': [2330], '(BMI)': [2333], '(kg)': [2338], 'divided': [2339], 'squared': [2342], '(m2).': [2343], 'follows:': [2351], 'days/month': [2358], 'average': [2360], 'drinks/day': [2361], '(gm': [2362], 'ethanol)': [2363], 'time.': [2367, 2576, 3255, 3458, 3529, 3845, 4200], 'Each': [2368], 'drink': [2369], 'contain': [2373], '10': [2374, 3025, 3078], 'gm': [2375], 'alcohol.22,': [2377], 'Statistical': [2379], 'Analysis': [2380], 'SAS': [2382], 'program': [2383], '(SAS': [2384], 'Institute,': [2385], 'Cary,': [2386], 'NC)': [2387], 'statistical': [2392, 2549, 2933], 'analyses.': [2393, 3737], 'Continuous': [2394], 'variables': [2395, 2406, 2414, 2423, 3965], 'medians': [2399, 2661], 'ranges.': [2401], 'Observations': [2402], 'continuous': [2405], 'compared': [2408, 2416, 2480, 2800, 3218, 3752, 3915], 'Wilcoxon': [2410], 'rank': [2411], 'tests.': [2412, 2420], 'Categorical': [2413], "Fisher's": [2418], 'exact': [2419], 'evaluated:': [2425], 'status,': [2427], 'ethnicity,': [2429], 'genotype,': [2439], 'immunosuppressives': [2442], 'antiviral': [2444, 3265, 3497], 'medications,': [2445], 'bilirubin': [2448, 3606, 3614], 'lipids,': [2450], 'hemoglobin': [2451, 3708], 'A1c,': [2452], 'glucose,': [2454], 'Finally,': [2459], 'Tacrolimus': [2471], 'follow-up': [2477], 'logistic': [2482, 2809], 'models.': [2484], 'correlations': [2486, 3330], 'dose': [2491, 3195, 3334, 3423], 'interferon': [2493, 3283, 3336], 'ribavirin': [2497, 3285, 3338], 'natural': [2500, 2524], 'log': [2501, 2525], '(HOMA-IR': [2504], 'HOMA2-IR)': [2506, 2665], 'mixed-effects': [2512, 2561], 'adjust': [2515], 'observations': [2518], 'same': [2521], 'across': [2528, 2575], 'outcome': [2535, 3901], 'interest': [2537, 2829], 'distribution': [2544], 'variable.': [2547], 'All': [2548, 3179], 'HOMA2-IR.': [2559], 'contributed': [2570], 'Variables': [2577, 2604], 'infection,': [2587], 'high-density': [2589, 3970, 4126], '(previously': [2592], 'IR2),': [2600], 'identified': [2605], 'confounders': [2607], 'clinically': [2612], 'relevant': [2613], 'entered': [2615, 2626], 'final': [2618, 2629, 3961], 'model.': [2619, 2759], 'abnormal': [2635], 'function': [2637, 2668, 4198], 'biopsies.': [2641], '(defined': [2655, 4148], 'above': [2659], 'RNA.': [2671], 'subject,': [2674], 'categorized': [2679, 4313], 'low': [2681, 3704, 4245, 4315], '(<600': [2682], '>60': [2685], 'i.e.,': [2687], 'undetectable': [2688], 'quantitative': [2690], 'detectable': [2692], 'assay),': [2695], 'medium': [2696, 4222, 4323], 'range': [2697], '(≥600': [2698, 4324], '≤500,000': [2701, 4327], 'IU/mL),': [2702, 4230, 4328, 4332], '(>500,000': [2705, 4211, 4331], 'IU/mL).': [2706, 4253], 'Then,': [2707], 'integrated': [2709, 2744, 4144, 4191, 4207, 4223, 4246, 4334], 'value': [2710, 2721, 3051, 3590, 4101, 4302], 'subject': [2712], 'mean': [2717, 3420, 4143, 4150, 4192, 4337], 'categorical': [2718], 'initial': [2724, 2833, 3541, 3724], '(month': [2727, 3545], '1)': [2728, 3576], 'reaching': [2730], 'HOMA.': [2732], 'establish': [2739], 'ealier.': [2752], 'evaluated.': [2769, 3566, 3858], '≥125': [2775], 'mg/dL': [2776], 'treated': [2780, 2960, 3182, 3280, 3300, 3391], 'hypoglycemic': [2782], 'defined': [2785], 'diabetics.': [2787], 'prevalence': [2789, 2921], '0': [2794, 2838, 3058, 3072], 'groups.': [2806, 2874, 2955], 'assess': [2814], 'incidence': [2816], 'while': [2830, 3820], 'status': [2835, 3727, 3851], 'RESULTS': [2840], 'baseline': [2844], 'demographics': [2845], 'are': [2847, 3887], 'summarized': [2848], 'Table': [2850, 3028, 3256, 3483, 3530, 3567, 4081, 4278], '1.': [2851, 3029], 'women': [2855], 'none': [2861], 'statistically': [2868, 3554, 3741, 4257], 'vast': [2876], 'majority': [2877, 2975], 'participants': [2879, 3180], 'both': [2881, 3821], 'Caucasian.': [2884], 'age': [2897], 'slightly': [2904], 'percentage': [2906], 'prior': [2915, 3102, 3805], 'pre-orthotopic': [2924], 'did': [2930], 'reach': [2932], 'significance.': [2934], 'lipid': [2962], 'lowering': [2963], 'agents': [2964], 'either': [2966], 'course': [2970, 3269], '1a': [2981], 'genotype.': [2982], 'subjects,': [2987], 'HCV(+),': [2989], 'elevated': [2994], 'enzymes.': [2996], 'Among': [2997], 'equal': [3006], 'scale.27': [3015], 'One': [3016], 'score': [3021], 'Demographic': [3030], 'Time': [3033, 3573, 4280], '20)': [3039, 3580], '14)': [3043, 3586], 'Median': [3044, 3047, 3581, 3587], '(range)': [3045, 3048, 3582, 3588], 'Frequency': [3046, 3049], 'P': [3050, 3376, 3589, 3763, 3782, 3882, 4100, 4301], 'Gender': [3052], '(M/F)': [3053], '–': [3054, 3062, 3071, 3085, 3088, 3094, 3097, 3105, 3110, 3120, 3125, 3135, 3138, 3142, 3143, 3144], '15M/5F': [3055], 'M/': [3057], 'F': [3059], '0.06': [3060], 'Race/ethnicity': [3061], 'A,': [3064, 3073, 3161], 'AA,': [3066, 3075, 3163], 'H,': [3068, 3077, 3166], '16': [3069], 'W': [3070, 3079], '0.5': [3080], 'Age': [3081], '(yr)': [3082], '54.5': [3083], '(30–71)': [3084], '51.5': [3086], '(25–66)': [3087], '0.35': [3089], '(kg/m2)': [3091], '24.9': [3092], '(21.5–40.9)': [3093], '24.2': [3095], '(18.8–28.6)': [3096], '0.2': [3098, 3612, 3668, 3691], 'History': [3099], 'DM': [3101, 3119], 'OLT': [3104], 'n': [3106, 3111, 3121, 3126], '6': [3108, 3145], '(30%)': [3109], '(36%)': [3114], '0.27': [3115], '9': [3123], '(45%)': [3124], '7': [3128], '(50%)': [3129], '0.8': [3130, 3661, 3675], 'EtOH': [3131], '(gm/lifetime)': [3132], '1584': [3133], '(0–6186)': [3134], '1548': [3136], '(0–8280)': [3137], '0.86': [3139], '(1a),': [3146], '(1b),': [3148], '(2b),': [3150], '2(3a),': [3151], '1(4c/d),': [3152], '(unknown)': [3154], 'NA': [3155], 'Abbreviations:': [3156, 3692], 'M,': [3157], 'Male;': [3158], 'F,': [3159], 'Female;': [3160], 'Asian;': [3162], 'African': [3164], 'American;': [3165], 'Hispanic;': [3167], 'W,': [3168], 'non-Hispanic': [3169], 'white;': [3170], 'DM,': [3171], 'mellitus;': [3173], 'EtOH,': [3174], 'ethanol;': [3175], 'NA,': [3176], 'applicable.': [3178], 'tacrolimus.': [3186], 'Figures': [3187], 'demonstrate': [3191], 'median': [3193], 'trend': [3209, 3435, 3862, 4034], 'toward': [3210, 3401, 3436, 4023], 'reflecting': [3223], 'concerted': [3224], 'efforts': [3225], 'minimize': [3227], 'institution': [3236], '0.06).': [3239, 3446], 'summarizes': [3258], 'response': [3263], 'treatment': [3266, 3305, 3522], 'pegylated': [3282, 3501], 'some': [3287], 'yr': [3292, 4076], 'contraindications': [3303], '(anemia).': [3306], '“responders”': [3317], '(achieved': [3318], 'undetectability': [3321], 'post-orthotopic': [3325], 'LT).': [3326], '(data': [3343], 'shown).': [3345, 3903, 4016], 'hypertension': [3360], '(7/14': [3365], '9/20': [3369], 'met': [3372], 'criteria': [3373], 'hypertension;': [3375], 'significant),': [3379], 'entire': [3388], 'medications.': [3394], 'Figure': [3395, 3447, 3890, 4017, 4053], '1Open': [3396], 'figure': [3398, 3450, 4020, 4056], 'viewerPowerPoint': [3399, 3451, 4021, 4057], 'Trend': [3400, 4022], 'subjects.': [3407, 4030, 4062], 'Using': [3408, 3459], 'maximum': [3411, 3462], 'likelihood': [3412, 3463], 'ratio,': [3413, 3464], 'daily': [3421], 'time,': [3430], 'although': [3431], '2Open': [3448], 'Comparable': [3452], '(FK506)': [3456], '0.09).': [3482], '2.': [3484], 'Summary': [3485], 'Antiviral': [3487], 'Therapy': [3488], '(PEG': [3489], 'IFN': [3490], 'Ribavirin)': [3492], 'NOTE:': [3493], 'Shaded': [3494], 'areas': [3495], 'indicate': [3496], 'treatment.': [3498], 'Abbreviations:PEG': [3499], 'IFN,': [3500], 'interferon;': [3502], 'D,': [3503], 'deceased;': [3504], 'N,': [3505], 'nonresponder': [3506], '(detectable': [3507], 'RNA);': [3509], 'N/A,': [3510], 'applicable;': [3512], 'R,': [3513], 'responder': [3514], '(undetectable': [3515], 'RNA).': [3517], '–,': [3518], 'indicates': [3519], 'being': [3524], 'specified': [3528], 'shows': [3532], 'testing': [3537], 'post-LT)': [3547], 'any': [3562], '3.': [3568, 3891], 'Chemistries': [3569], 'Initial': [3571], 'Post-LT': [3572, 4093], 'Point': [3574], '(Month': [3575], 'HCV(–)': [3577], 'AST': [3591], '(U/L)': [3592, 3599], '22': [3593], '(13–124)': [3594], '(10–38)': [3596], '0.9': [3597], 'ALT': [3598], '28': [3600, 3632], '(8–195)': [3601], '23.5': [3602], '(5–43)': [3603], '0.4': [3604, 3620, 3648, 3683], '(mg/dL)': [3607, 3615, 3622, 3629, 3636, 3643, 3656, 3663], '0.7': [3608, 3627], '(0.1–3.6)': [3609], '1.05': [3610], '(0.4–8.6)': [3611], 'Direct': [3613], '0.45': [3616], '(0.1–2.3)': [3617], '0.65': [3618], '(0.2–5.1)': [3619], 'Cholesterol': [3621], '127.5': [3623], '(61–264)': [3624], '123': [3625], '(90–202)': [3626], 'HDL': [3628, 4118], '24': [3630], '(5–73)': [3631], '(8–40)': [3633], '0.98': [3634, 3641], 'LDL': [3635], '80.5': [3637], '(18–157)': [3638], '73': [3639], '(48–137)': [3640], 'Triglycerides': [3642], '136.5': [3644], '(51–280)': [3645], '114.5': [3646], '(82–261)': [3647], 'HbA1c': [3649], '5.35': [3650], '(3.8–7.3)': [3651], '5.1': [3652], '(3.7–7.6)': [3653], '0.6': [3654], 'Glucose': [3655], '106': [3657], '(83–282)': [3658], '102': [3659], '(70–283)': [3660], '10.2': [3664], '(5.8–17.8)': [3665], '12.1': [3666], '(7.5–167.6)': [3667], 'C-peptide': [3669], '(pmol/L)': [3670], '1,000': [3671], '(130–3500)': [3672], '1,250': [3673], '(33–3100)': [3674], '(mU)(mmol)/L2': [3678], '2.9': [3679], '(1.3–7.1)': [3680], '3.1': [3681], '(1.8–66.6)': [3682], 'HOMA2': [3684], '(pmol)(mmol)/L2': [3686], '1.49': [3687], '(0.8–2.3)': [3688], '1.6': [3689], '(1–19.2)': [3690], 'AST,': [3693], 'aspartate': [3694], 'aminotransferase;': [3695, 3698], 'ALT,': [3696], 'alanine': [3697], 'HDL,': [3699, 4125], 'density': [3701, 3705], 'lipoprotein;': [3702, 3706], 'LDL,': [3703], 'HbA1c,': [3707], 'A1c.': [3709], 'Is': [3711], 'Independently': [3712], 'Associated': [3713], 'With': [3714, 4133], 'Increased': [3715, 4085], 'During': [3717, 4089], 'Yr': [3720], 'Posttransplantation': [3721], 'phase,': [3725], 'univariate': [3736, 3847, 4051], '(estimate': [3756, 3775, 3875], '0.24,': [3758, 3877], 'error': [3760, 3779, 3879], '0.12,': [3762], '0.049).': [3765], 'stronger': [3770], '0.36,': [3777], '0.13,': [3781], '0.007).': [3784], 'later': [3788], 'added': [3789], 'given': [3795], 'variable': [3802], 'cohorts.2': [3807], 'remained': [3825, 4256], 'insulin.': [3830], 'When': [3831], 'evaluating': [3832, 4190], 'towards': [3863, 4035], '0.18,': [3881], '0.19).': [3884], 'depicted': [3888], 'Similar': [3892], '(not': [3902, 4015], '0.01,': [3922], 'Fig.': [3923], '4)': [3924], 'confounder': [3932], 'words,': [3943, 4203], 'controlled': [3946], 'lipoprotein.': [3971, 4127], '(=': [3979, 3998], 'e0.57)': [3980], '0.0035)': [3986], '1-unit': [3989], '7%': [3997], 'e0.07)': [3999], '0.004)': [4005], '(Table': [4006, 4266], '4).': [4007], 'similar': [4014], '3Open': [4018], 'analysis.': [4052], '4Open': [4054], 'Lower': [4058], '4.': [4082], 'Predictors': [4083], 'Resistance': [4087], '(HOMA-IR)': [4088], 'Year': [4092], 'Covariate': [4094, 4293], 'Effect': [4095], 'ln': [4097], 'SE': [4099], '+HCV': [4102], '0.57': [4103], '(HCV': [4104], 'IR)': [4110], '0.18': [4111], '0.035': [4112], '0.07': [4114], '0.02': [4115], '0.002': [4116], 'High': [4117, 4284], '0.22': [4119], '0.19': [4120], '0.25': [4121], 'Abbreviations:SE,': [4122], 'error,': [4124], 'Levels': [4131], 'Correlate': [4132], 'More': [4134], 'Rapid': [4135], 'Development': [4136, 4282], 'Elevated': [4138], 'RNAs': [4152, 4340], 'attained)': [4165], 'hazard': [4182, 4269, 4299], 'ratio': [4183, 4270, 4295, 4300], '5.2': [4185, 4216, 4239, 4353], '0.03)': [4188], 'IU/mL)': [4212], '(>600': [4227], '<500,000': [4229], 'turn': [4234], '(>60': [4250, 4316], 'result': [4255], 'adjusting': [4260], '0.04)': [4265], '5).': [4267], '4.8': [4274], '0.037).': [4277], '5.': [4279], 'Function': [4288], 'Level': [4292], 'Hazard': [4294], '95%': [4296], 'CI': [4297], 'Integrated': [4303], '(low,': [4306], 'medium,': [4307], 'high)**': [4308], 'values': [4311], 'qualitatively': [4321], '+),': [4322], 'recorded.': [4352], '1.2–22.7': [4354], '0.03': [4355], 'Abbreviation:CI,': [4356], 'confidence': [4357], 'interval.': [4358]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2141557620', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 10}], 'updated_date': '2024-08-13T23:58:14.277739', 'created_date': '2016-06-24'}