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[40], 'developmentally': [41], 'downregulated': [42], '(gene': [43], '4)': [44], 'protein': [45, 78, 92], '(Nedd4‐2).': [46], 'During': [47], 'the': [48, 61, 76, 103], 'early': [49], 'phase': [50], 'aldosterone': [52], 'action,': [53], 'Nedd4‐2‐dependent': [54], 'downregulation': [55], 'inhibited': [59], 'serum‐': [62], 'glucocorticoid‐induced': [64], 'kinase': [65, 93], '1': [66], '(Sgk1).': [67], 'Sgk1': [68, 97], 'phosphorylates': [69], 'Nedd4‐2.': [70], 'Subsequently,': [71], 'phosphorylated': [72, 90], 'Nedd4‐2': [73, 84, 87, 115], 'binds': [74], 'to': [75, 85], '14‐3‐3': [77], 'and,': [79], 'hence,': [80], 'reduces': [81], 'binding': [82], 'ENaC.': [86, 118], 'also': [89], 'B': [94], '(Akt1).': [95], 'Both': [96], 'Akt1': [99], 'are': [100], 'part': [101], 'insulin': [104], 'signalling': [105], 'pathway': [106], 'that': [107], 'increases': [108], 'transepithelial': [109], 'Na': [110], '+': [111], 'absorption': [112], 'inhibiting': [114], 'activating': [117]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2140943956', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2025-01-18T13:04:49.819233', 'created_date': '2016-06-24'}