Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2140683589', 'doi': 'https://doi.org/10.1128/jcm.37.9.3068-3071.1999', 'title': 'Interactions between Methicillin and Vancomycin in Methicillin-Resistant <i>Staphylococcus aureus</i> Strains Displaying Different Phenotypes of Vancomycin Susceptibility', 'display_name': 'Interactions between Methicillin and Vancomycin in Methicillin-Resistant <i>Staphylococcus aureus</i> Strains Displaying Different Phenotypes of Vancomycin Susceptibility', 'publication_year': 1999, 'publication_date': '1999-09-01', 'ids': {'openalex': 'https://openalex.org/W2140683589', 'doi': 'https://doi.org/10.1128/jcm.37.9.3068-3071.1999', 'mag': '2140683589', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10449511', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/85462'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jcm.37.9.3068-3071.1999', 'pdf_url': 'https://jcm.asm.org/content/jcm/37/9/3068.full.pdf', 'source': {'id': 'https://openalex.org/S53087977', 'display_name': 'Journal of Clinical Microbiology', 'issn_l': '0095-1137', 'issn': ['0095-1137', '1070-633X', '1098-660X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://jcm.asm.org/content/jcm/37/9/3068.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057227631', 'display_name': 'Laurence Moore', 'orcid': 'https://orcid.org/0000-0003-2182-823X'}, 'institutions': [{'id': 'https://openalex.org/I1307034911', 'display_name': 'North Bristol NHS Trust', 'ror': 'https://ror.org/036x6gt55', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307034911']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Robin A. Howe', 'raw_affiliation_strings': ['Bristol Centre for Antimicrobial Research and Evaluation, Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol BS10 5NB,1 and'], 'affiliations': [{'raw_affiliation_string': 'Bristol Centre for Antimicrobial Research and Evaluation, Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol BS10 5NB,1 and', 'institution_ids': ['https://openalex.org/I1307034911']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005801305', 'display_name': 'Mandy Wootton', 'orcid': 'https://orcid.org/0000-0002-2227-3355'}, 'institutions': [{'id': 'https://openalex.org/I1307034911', 'display_name': 'North Bristol NHS Trust', 'ror': 'https://ror.org/036x6gt55', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307034911']}, {'id': 'https://openalex.org/I36234482', 'display_name': 'University of Bristol', 'ror': 'https://ror.org/0524sp257', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I36234482']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Mandy Wootton', 'raw_affiliation_strings': ['Bristol Centre for Antimicrobial Research and Evaluation, Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol BS10 5NB,1 and', 'Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD,2 United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Bristol Centre for Antimicrobial Research and Evaluation, Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol BS10 5NB,1 and', 'institution_ids': ['https://openalex.org/I1307034911']}, {'raw_affiliation_string': 'Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD,2 United Kingdom', 'institution_ids': ['https://openalex.org/I36234482']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103628007', 'display_name': 'Peter M. Bennett', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36234482', 'display_name': 'University of Bristol', 'ror': 'https://ror.org/0524sp257', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I36234482']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Peter M. Bennett', 'raw_affiliation_strings': ['Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD,2 United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD,2 United Kingdom', 'institution_ids': ['https://openalex.org/I36234482']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060427520', 'display_name': 'Alasdair MacGowan', 'orcid': 'https://orcid.org/0000-0002-6720-5268'}, 'institutions': [{'id': 'https://openalex.org/I1307034911', 'display_name': 'North Bristol NHS Trust', 'ror': 'https://ror.org/036x6gt55', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307034911']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Alasdair P. MacGowan', 'raw_affiliation_strings': ['Bristol Centre for Antimicrobial Research and Evaluation, Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol BS10 5NB,1 and'], 'affiliations': [{'raw_affiliation_string': 'Bristol Centre for Antimicrobial Research and Evaluation, Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol BS10 5NB,1 and', 'institution_ids': ['https://openalex.org/I1307034911']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5001917936', 'display_name': 'Timothy R. Walsh', 'orcid': 'https://orcid.org/0000-0003-4315-4096'}, 'institutions': [{'id': 'https://openalex.org/I36234482', 'display_name': 'University of Bristol', 'ror': 'https://ror.org/0524sp257', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I36234482']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Timothy R. Walsh', 'raw_affiliation_strings': ['Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD,2 United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD,2 United Kingdom', 'institution_ids': ['https://openalex.org/I36234482']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.52, 'has_fulltext': False, 'cited_by_count': 37, 'citation_normalized_percentile': {'value': 0.734871, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '37', 'issue': '9', 'first_page': '3068', 'last_page': '3071'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10195', 'display_name': 'Methicillin-Resistant Staphylococcus aureus Infections', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10195', 'display_name': 'Methicillin-Resistant Staphylococcus aureus Infections', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial Biofilms and Quorum Sensing Mechanisms', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12167', 'display_name': 'Microbial Identification and Diagnosis', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/vancomycin-resistance', 'display_name': 'Vancomycin Resistance', 'score': 0.562011}, {'id': 'https://openalex.org/keywords/antimicrobial-susceptibility-testing', 'display_name': 'Antimicrobial Susceptibility Testing', 'score': 0.511364}], 'concepts': [{'id': 'https://openalex.org/C2778980435', 'wikidata': 'https://www.wikidata.org/wiki/Q424027', 'display_name': 'Vancomycin', 'level': 4, 'score': 0.9271582}, {'id': 'https://openalex.org/C2779489039', 'wikidata': 'https://www.wikidata.org/wiki/Q188121', 'display_name': 'Staphylococcus aureus', 'level': 3, 'score': 0.8101887}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.7802056}, {'id': 'https://openalex.org/C2777052132', 'wikidata': 'https://www.wikidata.org/wiki/Q595158', 'display_name': 'Methicillin-resistant Staphylococcus aureus', 'level': 4, 'score': 0.715065}, {'id': 'https://openalex.org/C2777383412', 'wikidata': 'https://www.wikidata.org/wiki/Q4770891', 'display_name': 'Antagonism', 'level': 3, 'score': 0.70829415}, {'id': 'https://openalex.org/C2775965595', 'wikidata': 'https://www.wikidata.org/wiki/Q1365581', 'display_name': 'Micrococcaceae', 'level': 4, 'score': 0.49993825}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.49363673}, {'id': 'https://openalex.org/C2777334864', 'wikidata': 'https://www.wikidata.org/wiki/Q34879', 'display_name': 'Staphylococcal infections', 'level': 4, 'score': 0.491695}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.48760954}, {'id': 'https://openalex.org/C3019249092', 'wikidata': 'https://www.wikidata.org/wiki/Q274493', 'display_name': 'Antibacterial agent', 'level': 3, 'score': 0.41479677}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.27308077}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.054276347}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D008712', 'descriptor_name': 'Methicillin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D016106', 'descriptor_name': 'Methicillin Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010406', 'descriptor_name': 'Penicillins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D014640', 'descriptor_name': 'Vancomycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004347', 'descriptor_name': 'Drug Interactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008712', 'descriptor_name': 'Methicillin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010406', 'descriptor_name': 'Penicillins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014640', 'descriptor_name': 'Vancomycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jcm.37.9.3068-3071.1999', 'pdf_url': 'https://jcm.asm.org/content/jcm/37/9/3068.full.pdf', 'source': {'id': 'https://openalex.org/S53087977', 'display_name': 'Journal of Clinical Microbiology', 'issn_l': '0095-1137', 'issn': ['0095-1137', '1070-633X', '1098-660X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC85462', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10449511', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jcm.37.9.3068-3071.1999', 'pdf_url': 'https://jcm.asm.org/content/jcm/37/9/3068.full.pdf', 'source': {'id': 'https://openalex.org/S53087977', 'display_name': 'Journal of Clinical Microbiology', 'issn_l': '0095-1137', 'issn': ['0095-1137', '1070-633X', '1098-660X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1499823044', 'https://openalex.org/W1505626160', 'https://openalex.org/W1581962345', 'https://openalex.org/W1935563646', 'https://openalex.org/W1993364817', 'https://openalex.org/W2076091485', 'https://openalex.org/W2082816719', 'https://openalex.org/W2113091465', 'https://openalex.org/W2116657475', 'https://openalex.org/W2118094416', 'https://openalex.org/W2119439337', 'https://openalex.org/W2137366286', 'https://openalex.org/W2140777443', 'https://openalex.org/W2144005980', 'https://openalex.org/W4243503179'], 'related_works': ['https://openalex.org/W4388112408', 'https://openalex.org/W2141991591', 'https://openalex.org/W2134460529', 'https://openalex.org/W2131915708', 'https://openalex.org/W2106813024', 'https://openalex.org/W2091133457', 'https://openalex.org/W2078088092', 'https://openalex.org/W2066774883', 'https://openalex.org/W1999636845', 'https://openalex.org/W1591841737'], 'abstract_inverted_index': {'Vancomycin-sensitive,': [0], '-intermediate,': [1], 'and': [2, 19, 24], '-heterointermediate': [3, 25], 'methicillin-resistant': [4], 'Staphylococcus': [5], 'aureus': [6, 54], 'isolates': [7], 'were': [8], 'tested': [9], 'by': [10], 'using': [11], 'E-tests': [12], 'to': [13, 49], 'explore': [14], 'the': [15, 22, 42], 'interaction': [16], 'of': [17], 'methicillin': [18, 39], 'vancomycin.': [20], 'For': [21], 'vancomycin-intermediate': [23], 'strains': [26], 'both': [27], 'drugs': [28], 'showed': [29], 'antagonism': [30], 'at': [31, 38], 'concentrations': [32, 40], 'below': [33], 'their': [34], 'MICs': [35], 'but': [36], 'synergy': [37], 'near': [41], 'MIC.': [43], 'This': [44], 'property': [45], 'could': [46], 'be': [47], 'used': [48], 'screen': [50], 'for': [51], 'heterointermediate': [52], 'S.': [53], 'strains.': [55]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2140683589', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-08-13T19:51:57.258249', 'created_date': '2016-06-24'}