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3097, 3211, 3251], '315,': [123], '4Discovery': [125], 'benzimidazole': [127], 'derivatives': [128], 'as': [129, 178, 1656], 'orally': [130], 'active': [131], 'inhibitors:': [133], 'Optimization': [134], '3,5-disubstituted': [136], 'piperidine': [137], 'improve': [139], 'pharmacokinetic': [140], 'profileBioorganic': [141], '&': [142, 932, 3129, 3798], 'Medicinal': [143], 'Chemistry,': [144, 227, 1719], '26,': [146, 3420, 3437], '12Lack': [148], 'connexin': [150, 827, 830], '40': [151, 828], 'decreases': [152], 'sensitivity': [155], 'renin-secreting': [157], 'juxtaglomerular': [158, 503, 902, 1271, 1390, 1685, 2796, 2891, 3146, 3222, 3599], 'cells9': [159], 'February': [160, 212, 440, 963, 1002, 1056, 1693, 3158], 'Pflügers': [163], 'Archiv': [164], '-': [165], 'European': [166, 1731], '470,': [171], '6Expression': [173], 'multiple': [175], 'antihypertensive': [176, 3291], 'peptides': [177], 'a': [179, 741, 1104, 1633, 2676, 2683, 2844, 2896, 2960, 3779], 'fusion': [180], 'protein': [181, 495, 1268, 2962], 'chloroplast': [184], 'Chlamydomonas': [186], 'reinhardtii25': [187], 'November': [188, 1928, 2033, 2068, 2131, 2407, 2941, 2991], '2017': [189, 263, 305], 'Applied': [193], 'Phycology,': [194], '30,': [196], '3Angiotensin': [198], 'II': [199, 319, 626, 668, 772, 1560, 1743, 2308, 2400, 2933, 3268, 3327, 3351], 'Short-Loop': [200], 'FeedbackHypertension,': [201], '71,': [203, 3627], '6Vasoactive': [205], 'Factors': [206], 'Blood': [208, 2225], 'Pressure': [209, 2226], 'Children7': [211], '2018Phenotypic': [213], 'dissection': [214], 'mouse': [217, 502, 1420, 3225], 'Ren1d': [218], 'knockout': [219, 1868], 'by': [220, 462, 468, 829, 1409, 1414, 1454, 1490, 1713, 1959, 2150, 2628, 2682, 3028, 3071, 3266, 3521, 3650, 3745], 'complementation': [221], 'with': [222, 344, 428, 622, 674, 1262], 'human': [223, 2545, 2677, 2833, 3539], 'reninJournal': [224], 'Biological': [226, 1718], '293,': [229, 1154], '4Zebrafish': [231], 'mesonephric': [232], 'cells': [234, 281, 837, 1391, 2850, 2892, 3223], 'are': [235, 672, 2089], 'functionally': [236], 'conserved': [237], 'comprise': [239], 'two': [240], 'distinct': [241], 'morphological': [242], 'populationsSebastien': [243], 'Rider,': [245, 354], 'Helen': [246], 'C.': [247, 650, 683, 784, 788, 1572, 1574, 1843, 2106, 2155, 2342, 2384, 2653], 'Christian,': [248], 'Linda': [249, 355, 2455], 'J.': [250, 260, 302, 356, 366, 960, 1220, 1229, 1230, 1236, 2523, 2589, 3227], 'Mullins,': [251, 357], 'Amelia': [252], 'Howarth,': [254], 'Calum': [255, 361], 'MacRae,': [257, 363], 'John': [259, 301, 365, 1348], 'Mullins7': [261], 'April': [262, 790, 817, 1845, 1881, 1900, 3090], '312,': [271, 313], '4Bimodal': [273], 'dynamics': [274], 'granular': [276], 'organelles': [277], 'primary': [279], 'renin-expressing': [280], 'revealed': [282], 'using': [283, 3593], 'TIRF': [284], 'microscopyCharlotte': [285], 'Buckley,': [286], 'Alison': [287], 'Dun,': [289], 'Audrey': [290], 'Peter,': [291], 'Christopher': [292], 'Bellamy,': [293], 'Kenneth': [294], 'Rory': [297], 'Duncan,': [299], 'Mullins9': [303], 'January': [304, 531, 606, 1115, 1303, 2008, 3177, 3204, 3244], '1Reciprocal': [315], 'effect': [316, 763, 1779, 2956], 'angiotensin': [318, 625, 630, 771, 1559, 1781, 2307, 2399, 3267, 3326, 3333], 'collecting': [321, 676], 'duct': [322, 677], 'synthesisTakamitsu': [324], 'Saigusa1': [325], 'December': [326, 652, 751, 1079, 1370, 2462, 2878, 2911], '2015': [327, 369, 389], '309,': [335, 377], '11Renin': [337], 'expression': [338, 552, 941, 1163, 1172, 1485, 1683, 1824, 2366, 2476, 2671, 2721, 3280, 3542], 'developing': [340, 3290], 'zebrafish': [341], 'is': [342, 620, 1092, 1165, 1412, 3074, 3647, 3677, 3778], 'associated': [343, 621, 673], 'angiogenesis': [345], 'requires': [347], 'Notch': [349], 'pathway': [350, 2276], 'endotheliumSebastien': [352], 'Rachel': [358], 'F.': [359, 2162, 2199, 2205, 2487], 'Verdon,': [360], 'Mullins15': [367], '6Plasticity': [379], 'renal': [381, 666, 770, 1445, 1979, 2053, 2180, 2191, 2278, 2639, 2708, 2712, 3339, 3747], 'endocrine': [382, 1635], 'functionBirgül': [383], 'Kurt': [384], 'Armin': [386, 438, 566, 808, 858, 1431, 1615, 1691, 1879, 2031, 2165, 2525], 'Kurtz15': [387, 567], 'Physiology-Regulatory,': [394, 414, 969, 1008, 1121, 1767, 1851, 2039, 2114, 2506, 2597, 2661, 2782, 2816, 2947], 'Integrative': [395, 415, 970, 1009, 1122, 1768, 1852, 2040, 2115, 2507, 2598, 2662, 2783, 2817, 2948], 'Comparative': [397, 417, 972, 1011, 1124, 1770, 1854, 2042, 2117, 2509, 2600, 2664, 2785, 2819, 2950], '308,': [400], '6Renin': [402], 'release:': [403, 2753], 'role': [404, 1595, 1968], 'SNAREsMariela': [406], 'Mendez1': [407, 882], '2014': [409, 441, 2430], '307,': [420], '5Control': [422], 'secretion': [425, 950, 986, 1026, 1822, 1863, 3070, 3511, 3646, 3676, 3727, 3744], 'from': [426, 1392, 1977, 2092, 2549, 2851, 2893, 3788], 'kidneys': [427], 'cell': [430, 2670], 'hyperplasiaBirgül': [431], 'Kurt,': [432], 'Christian': [433], 'Karger,': [434], 'Charlotte': [435, 815, 855, 1871, 2876, 3088], 'Wagner,': [436, 856, 1872], 'Kurtz1': [439, 859, 1432, 1692, 1880, 2032, 2166, 2209], '306,': [449], '3The': [451], 'world': [452], 'pandemic': [453], 'vitamin': [455, 1752], 'D': [456, 727, 1753, 1922], 'deficiency': [457, 1196], 'could': [458], 'possibly': [459], 'be': [460], 'explained': [461], 'cellular': [463], 'inflammatory': [464], 'response': [465, 1102, 1535, 2085, 2368], 'activity': [466, 773, 1157, 1557], 'induced': [467, 1453, 3027], 'renin-angiotensin': [470, 1727, 1926, 2054, 2481, 2572, 3696], 'systemMarcelo': [471], 'Ferder,': [472], 'Felipe': [473], 'Inserra,': [474], 'Walter': [475], 'Manucha,': [476], 'León': [478], 'Ferder1': [479], 'June': [480, 1182, 1583, 1803, 2560, 2591, 3054, 3123], '2013': [481, 511, 532], 'Physiology-Cell': [486, 612, 3210], '304,': [489, 519], '11Role': [491], 'SNARE': [494], 'SNAP23': [496], 'on': [497, 550, 769, 1751, 1783, 1820, 2004, 2052, 2125, 2425, 2711, 2928, 2967, 3139, 3427, 3605, 3664], 'cAMP-stimulated': [498, 3538], 'release': [500, 1408, 1976, 2715, 3558, 3666, 3723], 'cellsMariela': [504], 'Mendez,': [505], 'Herbert': [507], 'Y.': [508], 'Gaisano1': [509], '5Mechanisms': [521], 'Diabetic': [523], 'ComplicationsJosephine': [524], 'Forbes,': [526], 'Mark': [528, 783], 'E.': [529, 709, 1222, 1569, 3235], 'Cooper1': [530], 'Physiological': [534, 820, 1329, 1903, 2563, 3180, 3804], 'Reviews,': [535, 821, 1330, 1904, 3181], '93,': [537], '1Role': [539, 3255, 3439], 'blood': [541, 1132, 1203, 1537, 1642, 3490, 3519], 'pressure': [542, 1133, 1204, 1447, 2710, 2791, 3491, 3520], 'mediating': [544], 'influence': [546], 'salt': [548, 2050, 2151, 2194], 'intake': [549, 2757], 'kidneyKatharina': [555], 'Machura,': [556], 'Björn': [557], 'Neubauer,': [558], 'Dominik': [559], 'Ramona': [561], 'Kettl,': [562], 'Andreas': [563], 'Groβ,': [564], 'May': [568, 883, 910, 1245, 1620, 2429], '2012': [569, 607], '302,': [577, 615], '10Hydrogen': [579], 'sulfide': [580], 'regulates': [581], 'cAMP': [582, 3078, 3604], 'homeostasis': [583], 'degranulation': [586], 'As4.1': [588, 3367], 'rat': [590, 1174, 1393, 1563, 1788, 2190, 2852, 2894, 3338, 3735, 3746], 'renin-rich': [591], 'kidney': [592, 840], 'cellsMing': [593], 'Lu*,': [594], 'Yi-Hong': [595], 'Liu*,': [596], 'Chui': [597], 'Ying': [598], 'Ho,': [599], 'Chi': [600], 'Xin': [601], 'Tiong,': [602], 'Jin-Song': [604], 'Bian1': [605], '1Increased': [617], 'excretion': [619], 'augmented': [623], 'urinary': [624], 'levels': [627, 2401], 'chronic': [629], 'II-infused': [631], 'hypertensive': [632, 681, 2405], 'ratsLiu': [633], 'Liu,': [634, 1831], 'Alexis': [635], 'Gonzalez,': [637], 'Michael': [638], 'McCormack,': [639], 'Dale': [640], 'Seth,': [642], 'Hiroyuki': [643, 706, 3149], 'Kobori,': [644, 707, 3150], 'Gabriel': [646, 713, 2318], 'Navar,': [647, 2319], 'Minolfa': [649], 'Prieto1': [651], '2011': [653, 716, 752], '301,': [661], '6Reciprocal': [663], 'changes': [664, 2051, 2637, 2759], 'ACE/ANG': [667], 'ACE2/ANG': [670], '1–7': [671], 'enhanced': [675], 'Goldblatt': [680], 'ratsMinolfa': [682], 'Prieto,': [684], 'Romer': [685], 'González-Villalobos,': [687], 'Fady': [688], 'T.': [689, 2312, 3175], 'Botros,': [690], 'Victoria': [691], 'Martin,': [693, 3230], 'Javier': [694], 'Pagán,': [695], 'Ryousuke': [696], 'Satou,': [697], 'Lucienne': [698], 'S.': [699, 1292, 2449], 'Lara,': [700], 'Yumei': [701], 'Feng,': [702], 'Fernanda': [703], 'B.': [704, 1226, 1352, 1510, 1566, 1794, 2201, 2770], 'Fernandes,': [705], 'Dulce': [708], 'Casarini,': [710, 1570], 'Navar1': [714], '300,': [724], '3Vitamin': [726, 1921], 'Renin-Angiotensin': [730, 734, 1317], 'SystemActivation': [731], 'System': [735, 2627, 3446], 'Heart': [737, 2611], 'FailureDocking': [738], 'alignment-3D-QSAR': [739], 'new': [742], 'class': [743], 'potent': [745], 'non-chiral': [747], 'indole-3-carboxamide-based': [748], 'inhibitors4': [750], 'Collection': [754], 'Czechoslovak': [756], 'Chemical': [757], 'Communications,': [758], '76,': [760], '12Developmental': [762], 'antenatal': [765], 'exposure': [766], 'betamethasone': [768], 'young': [776], 'adult': [777], 'sheepStephen': [778], 'Contag,': [780], 'Jianli': [781], 'Bi,': [782], 'Chappell,': [785], 'James': [787, 1842, 2099, 2652], 'Rose1': [789, 1844, 2654], '2010': [791, 818], '298,': [799], '4Physiology': [801], 'Kidney': [803, 3365], 'ReninHayo': [804], 'Castrop,': [805, 1347, 1606], 'Klaus': [806, 1180], 'Höcherl,': [807, 2153, 2196], 'Kurtz,': [809, 850, 1178, 1616, 2526, 2874, 3080], 'Frank': [810, 1607, 2028], 'Schweda,': [811, 1422, 1608, 1870, 2029, 2520], 'Vladimir': [812], 'Todorov,': [813, 2025], 'Wagner1': [816, 2877, 3089], '90,': [823], '2Replacement': [825], '45': [831], 'causes': [832], 'ectopic': [833], 'localization': [834, 3216], 'renin-producing': [836], 'but': [841, 1164, 1539, 2231, 3569, 3750], 'maintains': [842], 'vivo': [844], 'control': [845, 1602, 1973, 2870], 'gene': [848, 1682, 1942, 1957, 2023, 2720, 3541], 'expressionLisa': [849], 'Melanie': [851], 'Gerl,': [852], 'Wilhelm': [853], 'Kriz,': [854], 'August': [860, 2167, 2500, 2776], '2009': [861, 884, 911, 964, 1003, 1057], '297,': [869], '2CBP': [871], 'p300': [873], 'homeostasis:': [876], 'can': [877], 'they': [878], 'drive': [879], 'fate?Mariela': [881], 'Physiology-Heart': [889, 1149, 1809, 2468, 3060], 'Circulatory': [891, 1151, 1811, 2470, 3062], '296,': [894, 919, 975, 1014, 1065], '5Gap': [896], 'junctional': [897], 'intercellular': [898], 'communication': [899], 'apparatusJian': [903], 'Yao,': [904], 'Takashi': [905, 3199], 'Oite,': [906], 'Masanori': [908, 3197], 'Kitamura1': [909], '5Transcriptional': [921], 'Regulatory': [922, 2740], 'Functions': [923], 'Mammalian': [925], 'AP-Endonuclease': [926], '(APE1/Ref-1),': [927], 'an': [928, 1725, 2570], 'Essential': [929], 'Multifunctional': [930], 'ProteinAntioxidants': [931], 'Redox': [933], 'Signaling,': [934], '11,': [936], '3Altered': [938], 'central': [939], 'TRPV4': [940], 'lipid': [943], 'raft': [944], 'association': [945], 'related': [946, 1094, 3075], 'inappropriate': [948], 'vasopressin': [949, 3665], 'cirrhotic': [952], 'ratsFlávia': [953], 'Regina': [954], 'Carreño,': [955], 'Lisa': [956, 2459], 'Ji,': [958], 'Thomas': [961], 'Cunningham1': [962], '2Normotensive': [977], 'sodium': [978, 1097, 2006, 2756], 'loading': [979], 'normal': [981, 2002, 2403], 'man:': [982], 'during': [987, 2193, 3012], 'β-receptor': [988], 'blockadeSimon': [989], 'Mølstrøm,': [990], 'Nils': [991], 'H.': [992, 2204, 2773], 'Larsen,': [993], 'Jane': [994], 'Simonsen,': [996], 'Remon': [997], 'Washington,': [998], 'Peter': [1000, 1113], 'Bie1': [1001, 1114], '2Dense-core': [1016], 'vesicle': [1017], 'proteins': [1018], 'IA-2': [1019], 'IA-2β': [1021], 'affect': [1022], 'synthesis': [1024], 'through': [1027], 'β-adrenergic': [1029], 'pathwaySoo': [1030], 'Mi': [1031, 1275, 2972], 'Kim,': [1032, 1276, 2974, 2983, 2986], 'Franziska': [1033], 'Theilig,': [1034], 'Yan': [1035, 1758], 'Qin,': [1036], 'Tao': [1037], 'Cai,': [1038], 'Diane': [1039, 1283, 1356, 1495, 1609], 'Mizel,': [1040, 1284, 1357, 1496, 1610], 'Robert': [1041, 1279, 2453, 2493], 'Faulhaber-Walter,': [1042, 1280], 'Hiroki': [1043], 'Hirai,': [1044], 'Sebastian': [1045, 1504], 'Bachmann,': [1046, 1505], 'Josephine': [1047, 1506], 'P.': [1048, 1234, 1298, 1507, 1571, 1836, 1839, 2456], 'Briggs,': [1049, 1299, 1364, 1508, 1614], 'Abner': [1050], 'Notkins,': [1052], 'Jurgen': [1054, 1301, 1368, 1509, 1618], 'Schnermann1': [1055, 1302, 1369, 1619], '2Plasma': [1067], 'Renal': [1069, 1671, 2243, 2606, 2619, 2630], 'Renin': [1070, 1711, 2126, 2249, 2626, 2744, 3104, 3362, 3376, 3434, 3445, 3461], 'Concentrations': [1071], 'Adult': [1073, 2255], 'Sheep': [1074], 'After': [1075], 'Prenatal': [1076], 'Betamethasone': [1077], 'Exposure31': [1078], '2008': [1080, 1116], 'Reproductive': [1082], 'Sciences,': [1083, 3717, 3737, 3756, 3782], '15,': [1085, 3274, 3286, 3344], '8Chronic': [1087], 'activation': [1088], 'plasma': [1090, 1206, 2931], 'log-linearly': [1093], 'dietary': [1096, 2049], 'eliminates': [1099], 'natriuresis': [1100, 1452, 2000], 'pulse': [1105], 'change': [1106], 'total': [1108, 2761], 'body': [1109, 2762], 'sodiumMads': [1110], 'Kjolby,': [1111], '294,': [1127], '1Salt-sensing': [1129], 'mechanisms': [1130, 3473], 'hypertensionSergei': [1136], 'N.': [1137, 1349, 1577, 2322], 'Orlov,': [1138], 'Alexander': [1140], 'Mongin1': [1142], 'October': [1143, 1395, 2286, 2324, 2655, 2695, 3809, 3815], '2007': [1144, 1183, 1246, 1304], '4COX-2': [1156], 'determines': [1158], 'level': [1160, 2934], 'dispensable': [1166], 'for': [1167, 1658, 1724, 2245, 2265, 2569, 2843, 2898, 3316], 'acute': [1168, 1999], 'upregulation': [1169], 'kidneysCorina': [1175], 'Matzdorf,': [1176], 'Höcherl1': [1181], '292,': [1191, 1255, 1312], '6Growth': [1193], 'hormone': [1194, 3138], 'receptor': [1195, 1746, 1867, 3269, 3709], 'mice': [1198, 1261], 'results': [1199], 'reduced': [1201], 'systolic': [1202], 'renin,': [1207, 2185], 'increased': [1208, 2364], 'aortic': [1209], 'eNOS': [1210], 'expression,': [1211, 3761], 'altered': [1213], 'cardiovascular': [1214, 3684, 3699], 'structure': [1215], 'functionE.': [1217], 'Egecioglu,': [1218], 'I.': [1219], 'Andersson,': [1221], 'Bollano,': [1223], 'V.': [1224], 'Palsdottir,': [1225], 'G.': [1227, 1240, 1502], 'Gabrielsson,': [1228], 'Kopchick,': [1231], 'O.': [1232], 'Skott,': [1233], 'Bie,': [1235], 'Isgaard,': [1237], 'Bohlooly-Y,': [1239], 'Bergström,': [1241], 'Wickman1': [1244], 'Physiology-Endocrinology': [1251, 3164], 'Metabolism,': [1253, 3166], '5Regulation': [1257], 'Cre': [1263], 'recombinase-mediated': [1264], 'deletion': [1265, 2360], 'G': [1267], 'Gsα': [1269], 'cellsLimeng': [1272], 'Chen,': [1273, 1286], 'Soo': [1274], 'Mona': [1277, 1358], 'Oppermann,': [1278, 1359], 'Yuning': [1281, 1501, 1611], 'Huang,': [1282, 1503, 1612], 'Min': [1285], 'Maria': [1287], 'Luisa': [1288], 'Sequeira': [1289], 'Lopez,': [1290], 'Lee': [1291], 'Weinstein,': [1293], 'Ariel': [1295, 2498], 'Gomez,': [1296], 'Josie': [1297, 1363, 1613], '1Physiology': [1314], 'Local': [1316], 'SystemsMartin': [1318], 'Ali': [1320], 'Poyan': [1321], 'Mehr,': [1322], 'Reinhold': [1324], 'Kreutz1': [1325], 'July': [1326, 1515, 1761, 2348, 2531, 2810], '2006': [1327], '86,': [1332], '3Contribution': [1334], 'basolateral': [1337], 'isoform': [1338], 'Na-K-2Cl−': [1341], 'cotransporter': [1342], '(NKCC1/BSC2)': [1343], 'secretionHayo': [1346, 1605], 'Lorenz,': [1350], 'Pernille': [1351], 'Hansen,': [1353], 'Ulla': [1354], 'Friis,': [1355], 'Boye': [1360], 'Jensen,': [1362], 'Ole': [1365], 'Skøtt,': [1366], '2005': [1371], '289,': [1379], '6Electrophysiological': [1381], 'characterization': [1384], 'inward': [1387], 'rectifier': [1388], 'kidney15': [1394], '2004': [1396, 1434, 1463, 1516, 1584, 1621, 1694, 2725, 2855], 'The': [1398, 1465, 2011, 2727, 2857], '560,': [1403], '2Stimulation': [1405], 'prostaglandin': [1410, 1492], 'E2': [1411], 'mediated': [1413, 1778, 3649, 3678], 'EP2': [1415], 'EP4': [1417], 'receptors': [1418], 'kidneysFrank': [1421], 'Jürgen': [1423, 1876], 'Klar,': [1424, 1687], 'Shuh': [1425], 'Narumiya,': [1426], 'Rolf': [1427], 'Nüsing,': [1429], '287,': [1442, 1524], '3Elevated': [1444], 'perfusion': [1446, 2709], 'does': [1448], 'not': [1449, 1541, 2090, 3570], 'contribute': [1450], 'isotonic': [1455], 'saline': [1456], 'infusion': [1457, 3663], 'freely': [1459], 'moving': [1460], 'dogs9': [1461], '559,': [1470], '3Cellular': [1472], 'mechanism': [1473], 'releaseActa': [1476], 'Physiologica': [1477], 'Scandinavica,': [1478], '181,': [1480], '4Inhibition': [1482], 'nNOS': [1484, 2188], 'macula': [1488, 1600, 1860], 'densa': [1489, 1601], 'COX-2-derived': [1491], 'E2Alex': [1493], 'Paliege,': [1494], 'Carmen': [1497], 'Medina,': [1498], 'Anita': [1499], 'Pasumarthy,': [1500], 'Schnermann,': [1511, 1877], 'Tianxin': [1513], 'Yang1': [1514], '1Lesions': [1526], 'dorsal': [1529], 'noradrenergic': [1530], 'bundle': [1531], 'augment': [1532], 'loss': [1538], 'do': [1540], 'alter': [1542], 'hypothalamic': [1543], 'Fos': [1544], 'expressionBrain': [1545], 'Research': [1546, 3689], 'Bulletin,': [1547, 3690], '63,': [1549, 1738], '6High': [1551], 'glucose': [1552], 'concentration': [1553], 'stimulates': [1554, 3742], 'intracellular': [1555, 1784, 1960], 'generation': [1561], 'mesangial': [1564], 'cellsD.': [1565], 'Vidotti,': [1567], 'Cristovam,': [1573], 'Leite,': [1576], 'Schor,': [1578], 'Boim1': [1582], '286,': [1592, 1629, 1702], '6Permissive': [1594], 'nitric': [1597, 2866], 'oxide': [1598, 2867], '5Vitamin': [1631], 'D:': [1632], 'negative': [1634], 'regulator': [1636], 'renin–angiotensin': [1639], 'pressureThe': [1643], 'Steroid': [1646], 'Biochemistry': [1647, 3524, 3653], 'Molecular': [1649], 'Biology,': [1650, 1736], '89-90Citric': [1652], 'acid': [1653], 'cycle': [1654], 'intermediates': [1655], 'ligands': [1657], 'orphan': [1659], 'G-protein-coupled': [1660], 'receptorsNature,': [1661], '429,': [1663], '6988The': [1665], 'Extracellular': [1666], 'Cyclic': [1667], 'AMP-Adenosine': [1668], 'Pathway': [1669], 'PhysiologyAnnual': [1672], 'Review': [1673], '66,': [1677], '1Aldosterone': [1679], 'enhances': [1680], 'cellsJürgen': [1686], 'Helga': [1688], 'Vitzthum,': [1689], '2Tumor': [1704, 2018], 'Necrosis': [1705], 'Factor-α': [1706], 'Activates': [1707], 'NFκB': [1708], 'Inhibit': [1710], 'Transcription': [1712], 'Targeting': [1714], 'cAMP-responsive': [1715], 'ElementJournal': [1716], '279,': [1721, 2473, 2512, 2540], '2Evidence': [1723], 'intrarenal': [1726, 2571, 3661], 'lesser-spotted': [1732], 'dogfishJournal': [1733], 'Fish': [1735], '5Effect': [1740], 'ANG': [1742, 2932], 'type': [1744, 2964], 'I': [1745, 1782, 2965], 'antagonist': [1747], 'ACE': [1749, 2087, 2370], 'inhibitor': [1750], 'receptor-null': [1754], 'miceJuan': [1755], 'Kong,': [1756], 'Chun': [1759], 'Li1': [1760], '2003': [1762, 1804, 1846, 1882, 1901, 2009], '285,': [1773], '1ACE': [1775], 'non-ACE': [1777], 'mobilization': [1786], 'glomerular': [1789], 'arteriolesJeannine': [1790], 'Marchetti,': [1791], 'Claudia': [1792], 'Helou,': [1795], 'Catherine': [1796, 2061], 'Chollet,': [1797], 'Rabary': [1798], 'Rajerison,': [1799], 'François': [1801], 'Alhenc-Gelas1': [1802], '284,': [1814, 1857, 1890], '6Inhibition': [1816], 'cyclooxygenase-2:': [1818], 'effects': [1819, 2754, 3135, 3602], 'fetal': [1826, 2648], 'lambsHeather': [1827], 'Mertz,': [1829], 'Jingfang': [1830], 'Nancy': [1832], 'Valego,': [1834], 'Shawn': [1835], 'Stallings,': [1837], 'Jorge': [1838], 'Figueroa,': [1840], '4Preserved': [1859], 'densa-dependent': [1861], 'A1': [1865], 'adenosine': [1866], 'miceFrank': [1869], 'Bernhard': [1873, 2528], 'Krämer,': [1875, 2203], '4Secretory': [1892], 'Granule': [1893], 'ExocytosisRobert': [1894], 'Burgoyne,': [1896], 'Alan': [1898], 'Morgan1': [1899], '83,': [1906], '2The': [1908, 1967], 'Role': [1909], 'ACE2': [1911], 'Cardiovascular': [1913, 1916, 3637, 3702], 'PhysiologyTrends': [1914], 'Medicine,': [1917, 2137, 3405, 3638, 3703], '13,': [1919], 'system7': [1927], '2002': [1929, 2034, 2069, 2109, 2168, 2211], 'Cellular': [1933], 'Biochemistry,': [1934, 2435, 3371], '88,': [1936], '2Intracellular': [1938], 'Ca2+': [1939, 1970], 'transcriptionJournal': [1943], 'Hypertension,': [1945, 1963, 2837, 3272, 3284, 3342], '21,': [1947, 1965], '2Implication': [1949], 'Ref-1': [1951], 'repression': [1954], 'transcription': [1958], 'calciumJournal': [1961], 'dog': [1978], 'cortical': [1980, 3748], 'slicesEuropean': [1981], '458,': [1986], '1-2Purinergic': [1988], 'Receptors': [1989], 'Glomerulus': [1992], 'Vasculature': [1994], 'KidneyMechanisms': [1997], 'humans': [2003], 'low': [2005], 'diet1': [2007], '546,': [2016], 'necrosis': [2019], 'factor-α': [2020], 'inhibits': [2021, 2517, 2792, 3572], 'expressionVladimir': [2024], 'Markus': [2026], 'Müller,': [2027], '283,': [2045, 2077, 2120, 2176], '5Effects': [2047], 'ratsCatherine': [2057], 'Ingert,': [2058], 'Michèle': [2059], 'Grima,': [2060], 'Coquard,': [2062], 'Mariette': [2063], 'Barthelmebs,': [2064], 'Jean-Louis': [2066], 'Imbs1': [2067], '5Prostaglandins': [2079], 'that': [2080], 'increase': [2081], 'production': [2083], 'inhibition': [2088, 3336, 3773], 'derived': [2091], 'cyclooxygenase-1Hui-Fang': [2093], 'Cheng,': [2094, 2372], 'Sue-Wan': [2095], 'Wang,': [2096, 2374, 2378, 2650], 'Ming-Zhi': [2097, 2375], 'Zhang,': [2098, 2376, 2690], 'McKanna,': [2101, 2381], 'Richard': [2102, 2582, 3046], 'Breyer,': [2103], 'Raymond': [2105, 2383], 'Harris1': [2107, 2385], '3Effect': [2122, 3659], 'Sildenafil': [2124], 'Secretion': [2127], 'Human': [2129], 'Subjects29': [2130], '2016': [2132, 2259, 2408, 3124, 3310], 'Biology': [2135], '227,': [2139], '8Role': [2141], 'prostanoids': [2143], 'renin-angiotensin-aldosterone': [2148], 'intakeKlaus': [2152], 'Martin': [2154, 3085], 'Kammerl,': [2156, 2198], 'Karl': [2157], 'Schumacher,': [2158], 'Dirk': [2159], 'Endemann,': [2160], 'Horst': [2161], 'Grobecker,': [2163, 2206], '2Role': [2178], 'nerves': [2181, 3258], 'stimulation': [2183, 2646, 3261, 3277], 'COX-2,': [2186], 'cortex': [2192], 'deficiencyK.': [2195], 'Kees,': [2200], '282,': [2219], '3Cyclooxygenase-2': [2221], 'Inhibitors': [2222], 'Attenuate': [2223], 'Increased': [2224], 'Renovascular': [2228], 'Hypertensive': [2229, 2427], 'Models,': [2230], 'Not': [2232, 3005], 'Deoxycorticosterone-Salt': [2234], 'Hypertension.Hypertension': [2235], 'Research,': [2236, 2747, 3546, 3563, 3586, 3610], '25,': [2238, 3455, 3470], '6Importance': [2240], 'Nerves': [2244, 2620, 3003], 'Basal': [2246], 'Stimulated': [2248], 'mRNA': [2250, 2547, 2641, 3144, 3485, 3591, 3607], 'Levels': [2251], 'Fetal': [2253, 3307], 'Ovine': [2256, 3306], 'Kidneys5': [2257], 'Society': [2264, 3315], 'Gynecologic': [2266, 3317], 'Investigation,': [2267, 3318], '8,': [2269], '6Role': [2271], 'extracellular': [2274], 'cAMP-adenosine': [2275], 'physiologyEdwin': [2279], 'Jackson,': [2281], 'Raghvendra': [2283], 'Dubey1': [2285], '2001': [2287, 2325, 2349, 2387], '281,': [2295, 2333, 2357], '4Genetic': [2297], 'disruption': [2298], 'atrial': [2300, 2925], 'natriuretic': [2301, 2926], 'peptide': [2302, 2927], 'receptor-A': [2303], 'alters': [2304], 'levelsShang-Jin': [2309], 'Shi,': [2310], 'Huong': [2311], 'Nguyen,': [2313], 'Guru': [2314], 'Dutt': [2315], 'Sharma,': [2316], 'Kailash': [2321], 'Pandey1': [2323], '4Physiological': [2335], 'cyclooxygenase-2': [2338], 'kidneyRaymond': [2341], 'Harris,': [2343], 'Matthew': [2345], 'Breyer1': [2347], '1Genetic': [2359], 'COX-2': [2362], 'prevents': [2363], 'inhibitionHui-Fang': [2371], 'Jun-Ling': [2373], 'Su-Wan': [2377], 'James.': [2379], '280,': [2395], '3Review:': [2397], 'Intrarenal': [2398], 'states25': [2406], 'Renin-Angiotensin-Aldosterone': [2413], 'System,': [2414], '2,': [2416, 3640, 3705], '1_supplAntihypertensive': [2418], 'Effects': [2419], 'Acetic': [2421], 'Acid': [2422], 'Vinegar': [2424], 'Spontaneously': [2426], 'Rats22': [2428], 'Bioscience,': [2432], 'Biotechnology,': [2433], '65,': [2437], '12Renin-angiotensin': [2439], 'sympathetic': [2442, 3024, 3257], 'nervous': [2443, 3025], 'cardiac': [2446], 'pressure-overload': [2447], 'hypertrophyWendell': [2448], 'Akers,': [2450], 'Andrew': [2451], 'Cross,': [2452], 'Speth,': [2454], 'Dwoskin,': [2457], 'Cassis1': [2461], '2000': [2463, 2501, 2532, 2561, 2592], '6Novel': [2475], 'metanephric': [2484], 'organ': [2485], 'cultureVictoria': [2486], 'Norwood,': [2488], 'Marjorie': [2489], 'Garmey,': [2490], 'Jeffrey': [2491], 'Wolford,': [2492], 'Carey,': [2495], 'Gomez1': [2499], '2Store-operated': [2514], 'influx': [2516], 'secretionFrank': [2519], 'Günter': [2521], 'Riegger,': [2524], 'Krämer1': [2530], '1Identification': [2542], 'three': [2544], 'isoforms': [2548], 'alternative': [2550], 'tissue-specific': [2551], 'transcriptional': [2552], 'initiationPATRICK': [2553], 'SINN,': [2555], 'CURT': [2557], 'SIGMUND29': [2559], 'Genomics,': [2564], '3,': [2566], '1Evidence': [2568], 'rainbow': [2576], 'trout,': [2577], 'Oncorhynchus': [2578], 'mykissJ.': [2579], 'Anne': [2580], 'Brown,': [2581], 'Paley,': [2584], 'Shehla': [2585], 'Amer,': [2586], 'Stephen': [2588], 'Aves1': [2590], '278,': [2603], '6Exaggerated': [2605], 'Vasoconstriction': [2607], 'During': [2608, 3378], 'Exercise': [2609], 'Failure': [2612], 'PatientsCirculation,': [2613], '101,': [2615], '7Role': [2617], 'Stimulation': [2623], 'Reduced': [2629], 'Arterial': [2631], 'PressureHypertension,': [2632], '34,': [2634], '5Developmental': [2636], 'half-life': [2642], 'responses': [2644, 3577], 'lambsJinjuan': [2649], '1999': [2656, 2696, 2777, 2811], '277,': [2667, 2704, 2788, 2822], '4JG': [2669], 'partial': [2673], 'genomic': [2679], 'transgene': [2680], 'driven': [2681], 'minimal': [2684], 'promoterPatrick': [2686], 'Sinn,': [2688], 'Xiaoji': [2689], 'Curt': [2692], 'Sigmund1': [2694], '4Effect': [2706], 'function,': [2713], 'angiotensinogen': [2719], 'rats7': [2723], '520,': [2732], '1Species-Specific': [2734], 'Differences': [2735], 'Positive': [2737], 'Negative': [2739], 'Elements': [2741], 'Gene': [2745, 3355, 3417, 3458], 'EnhancerCirculation': [2746], '85,': [2749], '6Pressure-dependent': [2751], 'sodiumErdmann': [2763], 'Seeliger,': [2764], 'Katrin': [2765], 'Lohmann,': [2766], 'Benno': [2767], 'Nafz,': [2768], 'Pontus': [2769], 'Persson,': [2771], 'Wolfgang': [2774], 'Reinhardt1': [2775], '2Transmural': [2790], 'prorenin': [2793], 'processing': [2794], 'cellAtsuhiro': [2797], 'Ichihara,': [2798, 3148], 'Hiromichi': [2799], 'Suzuki,': [2800], 'Yutaka': [2801, 3151], 'Miyashita,': [2802, 3152], 'Mareo': [2803], 'Naitoh,': [2804], 'Matsuhiko': [2805, 3153], 'Hayashi,': [2806, 3154], 'Takao': [2808, 3156], 'Saruta1': [2809, 3157], '1Dissection': [2824], 'silencer': [2826], 'elements': [2827, 3531], 'first': [2829], 'intron': [2830], 'controlling': [2831], 'geneJournal': [2835], '17,': [2839], '7Pharmacological': [2841], 'evidence': [2842], 'K': [2845], 'ATP': [2846], 'channel': [2847], 'renin‐secreting': [2849], 'kidney8': [2853], '517,': [2862], '3Role': [2864], 'secretionArmin': [2873], '1998': [2879, 2912, 2942, 2992, 3055, 3091, 3159, 3178, 3205, 3245], '275,': [2887, 2920, 2953, 3000], '6Isolated': [2889], 'superfused': [2890], 'kidney:': [2895], 'model': [2897], 'study': [2899], 'secretionMargitta': [2902], 'Albinus,': [2903], 'Erhard': [2904], 'Finkbeiner,': [2905], 'Birgit': [2906], 'Sosath,': [2907], 'Hartmut': [2909], 'Osswald1': [2910], '6Effects': [2922, 3422], 'homologous': [2924], 'drinking': [2929], 'eelsTakamasa': [2936], 'Tsuchida,': [2937], 'Yoshio': [2939], 'Takei1': [2940], '5Inhibitory': [2955], 'calyculin': [2958], 'A,': [2959], 'Ser/Thr': [2961], 'phosphatase': [2963], 'inhibitor,': [2966], 'secretionChun': [2969], 'Sik': [2970, 2985], 'Park,': [2971], 'Hyun': [2973], 'Chae': [2975], 'Hun': [2976], 'Leem,': [2977], 'Yeon': [2978], 'Jin': [2979], 'Jang,': [2980], 'Hae': [2981], 'Won': [2982], 'Hyoun': [2984], 'Yoo': [2988], 'Sun': [2989], 'Hong1': [2990], '5Renal': [3002], 'Are': [3004, 3105], 'Involved': [3006], 'Sodium': [3008, 3173], 'Water': [3010], 'Retention': [3011], 'Mechanical': [3013], 'Ventilation': [3014], 'Awake': [3016], 'DogsAnesthesiology,': [3017], '89,': [3019], '4Changes': [3021], '42': [3029], 'days': [3030], 'head-down': [3032], 'bed': [3033], 'restDominique': [3034], 'Sigaudo,': [3035], 'Jacques-Olivier': [3036], 'Fortrat,': [3037], 'Anne-Marie': [3038], 'Allevard,': [3039], 'Alain': [3040], 'Maillet,': [3041], 'Jean-Marie': [3042], 'Cottet-Emard,': [3043], 'Annick': [3044], 'Vouillarmet,': [3045], 'Hughson,': [3048], 'Guillemette': [3049], 'Gauquelin-Koch,': [3050], 'Claude': [3052], 'Gharib1': [3053], '274,': [3065, 3099, 3168, 3213, 3253], '6Stimulation': [3067], 'NO': [3072], 'donors': [3073], 'pathwayArmin': [3079], 'Karl-Heinz': [3081], 'Götz,': [3082], 'Marlies': [3083], 'Hamann,': [3084], 'Kieninger,': [3086], '4Angiotensinogen,': [3101], 'Prorenin,': [3102], 'Co-localized': [3106], 'Secretory': [3109], 'Granules': [3110], 'All': [3112], 'Glandular': [3113], 'Cells': [3114, 3303], 'Rat': [3117], 'Anterior': [3118], 'Pituitary:': [3119], 'An': [3120], 'Immunoultrastructural': [3121], 'Study26': [3122], 'Histochemistry': [3128], 'Cytochemistry,': [3130], '46,': [3132], '3Differential': [3134], 'thyroid': [3137], 'secretion,': [3141, 3488], 'content,': [3142], 'cellsAtsuhiro': [3147], '2Angiotensin,': [3170], 'Thirst,': [3171], 'AppetiteJ.': [3174], 'FITZSIMONS7': [3176], '78,': [3183], '3ATP-sensitive': [3185], 'K+': [3186], 'channels': [3187], 'pancreatic,': [3189], 'cardiac,': [3190], 'vascular': [3192], 'smooth': [3193], 'muscle': [3194], 'cellsHisashi': [3195], 'Yokoshiki,': [3196], 'Sunagawa,': [3198], 'Seki,': [3200], 'Nicholas': [3202], 'Sperelakis1': [3203], '1Distinct': [3215], 'GLUT-4': [3220], 'kidneyTimothy': [3226], 'Anderson,': [3228], 'Sally': [3229], 'Jennifer': [3231, 3241], 'Berka,': [3233], 'David': [3234], 'James,': [3236], 'Jan': [3237], 'Slot,': [3239], 'Stow1': [3243], 'fo': [3259], 'blockadeJournal': [3270], '12Beta-adrenergic': [3276], 'vivoJournal': [3282], '12New': [3288], 'or': [3289], 'agentsCurrent': [3292], 'Opinion': [3293], 'Cardiology,': [3295, 3625], '12,': [3297], '4Developmental': [3299], 'Changes': [3300], 'Renin-Containing': [3302], 'From': [3304], 'Kidney5': [3308], '4,': [3320], '4Role': [3322], 'kinins': [3324], 'vasodilating': [3330], 'action': [3331], 'converting': [3334], 'enzyme': [3335], 'vesselsJournal': [3340], '6Dietary': [3346], 'Salt': [3347], 'Intake': [3348], 'Modulates': [3349], 'Angiotensin': [3350], 'Type': [3352], '1': [3353, 3808, 3814], 'Receptor': [3354], 'ExpressionHypertension,': [3356, 3418], '29,': [3358], '4Biosynthesis': [3360], 'Mouse': [3364], 'Tumor': [3366], 'CellsEuropean': [3368], '243,': [3373], '1-2Pressure-Dependent': [3375], 'Release': [3377], 'Chronic': [3379], 'Blockade': [3380], 'Nitric': [3382], 'Oxide': [3383], 'SynthaseHypertension,': [3384], '28,': [3386, 3692], '5Role': [3388], 'epinephrine-induced': [3390], 'hypokalemia': [3391], 'aldosterone': [3398], 'humansJournal': [3400], 'Laboratory': [3402], '127,': [3407], '1Renal': [3409], 'Artery': [3410], 'Stenosis': [3411], 'Rapidly': [3412], 'Enhances': [3413], 'Atrial': [3414], 'Natriuretic': [3415], 'Peptide': [3416], 'Furosemide': [3424], 'Verapamil': [3426], 'NaCl': [3429], 'Dependency': [3430], 'Macula': [3432], 'Densa–Mediated': [3433], 'SecretionHypertension,': [3435], 'Endogenous': [3441], 'Endothelins': [3442], 'Normal': [3448], 'Two-Kidney,': [3450], 'One': [3451], 'Clip': [3452], 'RatsHypertension,': [3453], '5Differential': [3457], 'Expression': [3459], 'Angiotensinogen': [3463], 'TGR(mREN-2)27': [3466], 'Transgenic': [3467], 'RatHypertension,': [3468], '4Molecular': [3472], 'controlThe': [3476], 'Investigator,': [3478], '72,': [3480], '9Interrelation': [3482], 'between': 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