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'paradoxically': [448], 'had': [449, 493], 'consistent': [456], 'prior': [458], 'literature.4': [459], 'In': [460, 1130], '22': [462], '(56%)': [464], 'adjusted': [466, 479], 'other': [468, 2915], 'covariates,': [469], 'demonstrated': [472, 1095, 1242], 'same': [474], 'AMI': [478, 527, 569, 616, 643, 662, 711, 884, 920, 957, 993, 1134, 1177, 1184, 1223, 1325, 1383], 'revascularization': [487], 'treatment,': [488], 'which': [489, 637, 862, 976], 'protocolized,': [492], 'similar': [494], 'male': [497, 801, 865], 'mortality.': [498], 'Only': [499], 'study': [501, 717], '(3%)': [502], 'included': [503], 'medical': [504], 'treatment': [505, 1185, 1235], 'reported': [507, 718], 'mortality.Why': [510], 'there': [512, 705, 2314], 'heterogeneity,': [515], 'what': [517], 'teach': [520], 'us': [521], 'about': [522, 678, 1160], 'sex-death-MI': [524], 'gap?': [526], 'triad': [532], '(1)': [534, 1351], 'symptoms,': [535, 958, 1026], '(2)': [536, 1356], 'ECG,': [537], '(3)': [539], 'biomarker': [541, 1386], 'evidence': [542, 1319], 'cell': [545], 'Among': [547], 'these,': [548], 'objective': [551], 'criteria': [552, 567, 683, 712, 778], 'biomarkers.': [555], 'The': [556, 665, 1218, 1471, 1481, 1789, 2940, 3050], 'varying': [558], 'time': [559], 'frames,': [560], 'from': [561, 823, 1437, 1461, 1706, 1728, 2441, 3061], '1951': [562], '2008,': [564], 'when': [565], 'serological': [566], 'progressively': [570], 'changed,': [571], 'preclude': [572], 'meta-analyses': [575], 'but': [576, 704, 986], 'also': [577], 'conclusions.': [580], 'work,': [583], 'however,': [584], 'call': [586], 'attention': [587], 'long': [591], 'ignored': [592], 'science': [595], 'practice.': [597], 'Established': [598], 'normative': [599], 'standard': [600], 'creatine': [603, 1422, 1852], 'kinase5': [604], 'troponin6': [606], 'assays': [607], 'clearly': [608], 'demonstrate': [609, 758], 'reference': [613, 787, 1846], 'thresholds': [614, 625, 632, 1323, 1354], 'versus': [620], 'men;': [621], 'example,': [623, 1008], 'appropriate': [627, 873, 1254, 1344], 'yet': [630, 744, 834], 'male-standard': [631], 'used': [634, 789], 'practice,7': [636], 'detection': [641], 'Indeed,': [646], 'initial': [648], 'suggests': [650, 813, 1058], 'current': [653, 837, 1125], 'high-sensitivity': [654], 'troponin': [655, 1353, 1850, 2177], 'threshold': [656], 'failed': [657], 'detect': [659], '20%': [660, 1150], 'women.8': [664], 'associated': [666, 1197], 'mortality8': [669], 'argues': [670], 'against': [671, 1272], '"troponitis"': [673], 'explanation.What': [674], 'know': [677], 'ECG': [682, 686, 710, 756, 786, 805, 1380, 2101], 'AMI?': [685, 1166], 'abnormalities': [687], 'less': [689, 1076, 1250], 'likely': [690, 1251, 2921], 'diagnostic': [693, 925, 945, 1127, 1133, 2352], 'obstructive': [695, 1077, 1110, 1211], 'artery': [697, 1080, 1112, 1213], 'little': [707], 'work': [708, 1057, 1240, 1432], 'evaluating': [709], 'stratified': [713], 'sex.': [715], 'One': [716], 'post-MI': [720], 'ST-segment': [721], 'elevation': [722], 'anterior': [724], 'leads': [725, 739], 'predictor': [729], 'events': [731, 741, 2214], 'females,': [733], 'whereas': [734, 774, 996, 1190], 'ST': [735], 'depression': [736], 'lateral': [738], 'predicted': [740], 'males,9': [743], 'been': [748], 'repeated': [749], 'incorporated': [751], 'into': [752], 'clinical': [753, 808, 911, 2889, 3022], 'care.': [754], 'Many': [755], 'variables': [757], 'differences.': [760, 1003], 'Women': [761, 817, 1071, 1388, 2394, 2582, 2615, 2793], 'longer': [764], 'corrected': [765], 'QT': [766, 2237], 'interval': [767], 'greater': [769], 'sensitivity': [770], 'QT-prolonging': [772], 'medications,10': [773], 'left': [775, 796, 819, 1427, 2261], 'ventricular': [776, 797, 1428, 2262], 'hypertrophy': [777, 798], 'differ': [779, 898], 'sex.11': [781], 'Despite': [782], 'these': [783, 804], 'published': [784], 'data,': [785], 'standards': [788], 'practice': [791], 'ischemia,': [793], 'QT,': [794], 'thresholds.': [802], 'Do': [803], 'impact': [807], 'outcomes?': [809], 'publication': [812, 2589, 2636, 2696, 2738, 2761, 2850, 2899, 2931, 2962, 3010, 3033, 3074], 'can.': [816], 'bundle-branch': [820], 'block': [821], 'benefit': [822], 'resynchronization': [825, 868, 2284], 'therapy': [826, 869, 1345, 2285], 'shorter': [829], 'QRS': [830, 857], 'duration': [831, 858], 'men,12': [833], 'because': [835], 'US': [838, 2288], 'guidelines': [839], 'Class': [842], 'IIa': [843], 'recommendation': [844], '(benefit': [845], '>>': [846], 'risk;': [847], 'additional': [848], 'focused': [851], 'objectives': [852], 'needed': [853], 'patients': [855, 916, 1016, 1170, 1821, 2216], '130–149': [860], 'ms),': [861], 'standard,': [866], 'underused': [871], 'men.12More': [877], 'analyses': [878, 999], 'evaluated': [880, 2436], 'symptoms.': [885, 1366], 'Studies': [886], 'can': [887, 1308], 'cited': [889], 'support': [891, 1000, 1284], 'refute': [893], 'substantially': [899], 'symptom': [901, 998], 'presentation.13': [902], 'controversy': [904], 'explained': [906], 'case': [908], 'selection': [909], 'registries': [912], 'trials,': [914], 'whereby': [915], 'typical': [919, 956, 965], 'symptoms': [921, 966], 'selected': [923], 'testing.': [926], 'Pretesting': [927], '(ECG': [928], 'troponin)': [930], 'posttesting': [932], '(stress': [933], 'test,': [934], 'catheterization)': [935], 'referral': [936], 'bias': [937, 2348], 'selects': [938], 'population': [940], 'studied': [941], 'impacts': [943], 'accuracy': [946, 2353], 'testing.14': [948], 'Stated': [949], 'if': [952], 'will': [961, 967, 989], 'tested,': [963], 'specificity': [971], 'true': [978], 'literature.': [981], 'Accordingly,': [982], 'using': [984, 1384, 2501], 'biased': [987], 'populations': [988], 'accurately': [991], 'assess': [992], 'broad-net': [997], 'important': [1001, 1368], 'Canto': [1004, 1781, 2358], 'al,15': [1006], 'large': [1011], '>470': [1014], '000': [1015], 'syndrome,': [1020], 'found': [1021], 'including': [1027, 1350], '37.5%': [1029], '27.4%': [1034], 'presented': [1037], 'chest': [1039, 2513], 'pain.Do': [1040], 'others': [1041], 'factors': [1042], 'contribute': [1043, 1065], 'dying': [1046], 'MI?': [1055], 'Prior': [1056, 1239], 'presentation': [1064, 2373], 'death-diagnosis': [1068], 'gap.': [1070], 'angiography': [1074, 1215, 2506], 'angiographic': [1078, 1128], 'despite': [1082], 'being': [1083], 'factor': [1089], 'burden': [1090], 'men.16': [1092], 'female-specific': [1097], 'pattern': [1098], 'characterized': [1101], 'microvascular': [1104, 2427], 'dysfunction': [1105], 'symptomatic': [1107], 'adverse': [1117, 2432], 'prognosis17': [1118], 'routinely': [1122], 'recognized': [1123], 'male-pattern': [1126], 'strategies.': [1129], 'short,': [1131], 'existing': [1132], 'strategies': [1137, 1260, 1357], 'developed': [1138], 'fail': [1146], 'diagnose': [1148, 1194], 'approximately': [1149], 'IHD.Why': [1156], 'Without': [1167], 'diagnosis,': [1169, 1328, 1343], 'treated.': [1173], 'Failure': [1174], 'obvious': [1181], 'lack': [1182, 1288], 'elevated': [1187], 'rates,18': [1189], 'aspirin,': [1202], 'lipid-lowering': [1203], 'agent,': [1204], 'β-blocker': [1206], 'use': [1207, 1857], '"no': [1210], 'disease"': [1214], 'before.19': [1217], 'presence': [1219], 'CHD,': [1225], '"male-pattern"': [1227], 'IHD,': [1228], 'remains': [1229], 'key': [1231], 'decision': [1232], 'point': [1233], 'practicing': [1237], 'physicians.': [1238], 'syndrome': [1248, 2320], 'receive': [1253], 'guidelines-based': [1255], 'therapy,': [1256], 'implementation': [1258, 2536], 'close': [1262], 'guideline': [1263], 'gaps': [1264, 1334], 'preferentially': [1265], 'saves': [1266], "women's": [1267], 'lives.20': [1268], 'These': [1269], 'findings': [1270], 'argue': [1271], 'misogynistic': [1273], 'sexism': [1274], 'driving': [1277], 'force': [1278], 'sex-death-diagnosis': [1281], 'gap': [1282, 1370], 'concept': [1286], 'recognition': [1290], 'biological': [1292], 'sex-based': [1293, 2532], 'result': [1299], 'treat': [1303], 'cause.How': [1307], 'improve': [1310, 1342], 'outcomes': [1312, 3023], 'women?': [1314], 'currently': [1316], 'sufficient': [1318], 'implement': [1321], 'well': [1330, 1498], 'address': [1332], 'knowledge': [1333, 1369, 1418], '(Figure).': [1335], 'Guidelines': [1336, 2129], 'should': [1337], 'incorporate': [1338, 1360], '"female-pattern': [1339], 'IHD"': [1340], 'use,': [1346], 'explicitly': [1359], 'assessment': [1361], 'common': [1363], 'non–chest': [1364], 'pain': [1365], 'An': [1367], 'research': [1372, 2573, 2577], 'investigate': [1375], 'standards.': [1387], '51%': [1390], 'population;': [1393], 'addressing': [1394], 'their': [1397, 2210], 'leading': [1398], 'killer': [1399], 'must': [1400], 'our': [1404], 'highest': [1405], 'priorities.Download': [1406], 'figureDownload': [1407], 'PowerPointFigure.': [1408], 'Acute': [1409], '(AMI):': [1412], 'gaps.': [1419], 'CKMB': [1420], 'indicates': [1421], 'kinase-MB': [1423], 'fraction;': [1424], 'LVH,': [1426], 'hypertrophy.Sources': [1429], 'FundingThis': [1431], 'supported': [1434], 'contracts': [1436], 'National': [1439, 2443, 3063], 'Heart,': [1440, 2444, 2845], 'Lung,': [1441], 'Blood': [1443, 2447], 'Institutes': [1444], '(No.': [1445], 'N01-HV-68161,': [1446], 'N01-HV-68162,': [1447], 'N01-HV-68163,': [1448], 'N01-HV-68164,': [1449], 'RO1-HL-073412-01);': [1451], 'grants': [1452, 1460], 'U0164829,': [1453], 'U01': [1454, 1457], 'HL649141,': [1455], 'HL649241;': [1458], 'Gustavus': [1463], 'Louis': [1465], 'Pfeiffer': [1466], 'Research': [1467, 1510], 'Foundation': [1468], '(Danville,': [1469], 'NJ),': [1470, 1496], 'Guild': [1473], 'Center': [1477], '(Los': [1478], 'CA),': [1480], 'Ladies': [1482], 'Hospital': [1483], 'Aid': [1484], 'Society': [1485, 1552, 1860], 'Western': [1487], 'Pennsylvania': [1488], '(Pittsburgh,': [1489], 'PA),': [1490], 'QMED,': [1492], 'Inc': [1493], '(Laurence': [1494], 'Harbor,': [1495], 'Edythe': [1501], 'L.': [1502], 'Broad': [1503], 'Endowment,': [1504, 1527], 'Education': [1512], 'Program,': [1513, 1521], 'Linda': [1515], 'Joy': [1516], 'Pollin': [1517], 'Health': [1520, 2242, 3068], 'Constance': [1524], 'Austin': [1525], 'Fellowship': [1526], 'CA.DisclosuresDr': [1533], 'reports': [1536], 'industry': [1537], 'relationships': [1538], 'last': [1541], '2': [1542], 'years': [1543], '(all': [1544], '<$10': [1545], '000):': [1546], 'Gilead': [1547], '(grant': [1548], 'review),': [1549], 'Japanese': [1550], 'Circulation': [1551], '(speaker),': [1553], 'Bristol-Meyers': [1555], 'Squibb': [1556], '(Data': [1557], 'Safety': [1559], 'Monitoring': [1560], 'Board).FootnotesThe': [1561], 'opinions': [1562], 'expressed': [1563], 'editorial': [1566], 'necessarily': [1569], 'those': [1570, 2919], 'editors': [1573], 'American': [1577, 1689, 1708, 3002, 3088], 'Association.Correspondence': [1579], 'MD,': [1585, 1632], '127': [1589], 'S': [1590, 2938], 'San': [1591], 'Vicente': [1592], 'Blvd,': [1593], 'CA': [1596], '90048.': [1597], 'E-mail': [1598], '[email': [1599], 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