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550, 642, 699, 852, 902, 912, 918, 953, 990, 1006, 1023, 1115, 1117, 1125, 1230, 1236, 1249, 1296, 1539, 1648, 1658, 1698, 1702, 1717, 1730, 1741, 1747, 1754, 1793, 1826, 1860, 1943, 1980, 1995, 2027, 2089, 2101, 2155, 2158, 2204, 2226, 2237, 2243, 2262, 2279, 2286, 2292, 2329, 2358, 2362, 2384, 2439, 2447, 2470, 2510, 2517, 2732, 2761, 2850, 2900, 2915, 2953, 2959, 2999, 3011, 3071, 3078, 3082, 3159, 3208, 3216, 3267, 3343, 3419, 3463, 3467, 3619, 3711, 3768, 3922, 3972, 3982, 3988, 4023, 4061, 4077, 4094, 4186, 4188, 4196, 4301, 4307, 4320, 4368], 'human': [8, 102, 115, 204, 298, 311, 1389, 1650, 1669, 1677, 2519, 3358, 3365, 4461], 'mouse': [10, 206, 1308, 1541, 1652, 2512, 4380], 'genes': [11, 35, 207, 231, 1795, 2597, 2627, 3446], 'for': [12, 136, 208, 332, 455, 1017, 1398, 1687, 2539, 2585, 2623, 2745, 2909, 2921, 2927, 3055, 3067, 3340, 3347, 3524, 4088, 4470], 'vascular': [13, 25, 209, 221, 457, 460, 470, 483, 507, 520, 3526, 3529, 3539, 3552, 3576, 3589], 'endothelial': [14, 26, 210, 222, 461, 471, 484, 508, 521, 637, 3530, 3540, 3553, 3577, 3590, 3706], 'growth': [15, 27, 29, 211, 223, 225, 395, 430, 453, 462, 472, 476, 480, 485, 509, 513, 517, 522, 544, 553, 630, 993, 1503, 1704, 1769, 2625, 3464, 3499, 3522, 3531, 3541, 3545, 3549, 3554, 3578, 3582, 3586, 3591, 3613, 3622, 3699, 4064], 'factor': [16, 30, 212, 226, 463, 486, 523, 545, 554, 994, 1504, 1770, 2626, 2765, 2925, 3532, 3555, 3592, 3614, 3623, 4065], 'C': [17, 213, 1221, 1938, 4292], '(VEGF-C),': [18, 214], 'a': [19, 86, 106, 215, 282, 302, 410, 548, 910, 1227, 1237, 1606, 1727, 1841, 1861, 1936, 1951, 2232, 2249, 2255, 2326, 2336, 2485, 2534, 2587, 2615, 2633, 2951, 2957, 3214, 3479, 3617, 3980, 4298, 4308], 'newly': [20, 216, 3350], 'isolated': [21, 217], 'member': [22, 218, 1697], 'factor/platelet-derived': [28, 224], '(VEGF/PDGF)': [31, 227], 'family.': [32, 195, 228, 391], 'Both': [33, 229, 732, 3801], 'VEGF-C': [34, 58, 116, 157, 230, 254, 312, 353, 919, 954, 1112, 1224, 1653, 1660, 1831, 1875, 1981, 2094, 2139, 2165, 2199, 2238, 2513, 2520, 2570, 2734, 2768, 2829, 3013, 3046, 3210, 3250, 3359, 3426, 3989, 4024, 4183, 4295], 'comprise': [36, 232], 'over': [37, 233], '40': [38, 234], 'kilobase': [39, 235, 492, 529, 3561, 3598], 'pairs': [40, 120, 236, 316], 'genomic': [42, 238, 1656, 1678, 1715], 'DNA': [43, 239], 'consist': [45, 241, 1114, 4185], 'seven': [47, 243], 'exons,': [48, 244, 1805], 'all': [49, 245, 1785, 1811, 1823], 'containing': [50, 246, 1680, 2202, 2339], 'coding': [51, 247, 2514, 2528], 'sequences.': [52, 248, 2578], 'The': [53, 127, 156, 249, 323, 352, 392, 1111, 1388, 1655, 1714, 1789, 2087, 2839, 2997, 3147, 3205, 3461, 4182, 4364, 4460], 'VEGF': [54, 175, 250, 371, 643, 692, 791, 1263, 1298, 1542, 1609, 1700, 1709, 1757, 1996, 2294, 2385, 2541, 3043, 3073, 3148, 3265, 3366, 3712, 3761, 3861, 4334, 4370], 'homology': [55, 176, 251, 372, 1964, 2295], 'domain': [56, 252, 1229, 1864, 1947, 2296, 4300], 'is': [59, 160, 255, 356, 405, 693, 920, 1488, 1614, 1672, 1694, 1820, 1840, 1872, 1948, 2356, 2489, 2621, 2629, 2832, 2937, 2945, 3075, 3151, 3353, 3474, 3762, 3990], 'encoded': [60, 256, 1256, 1799, 1847, 1974, 3246, 4327], 'by': [61, 257, 704, 741, 998, 1122, 1257, 1612, 1800, 1848, 1975, 2254, 2836, 2950, 3015, 3156, 3234, 3773, 3810, 4069, 4193, 4328], 'exons': [62, 164, 258, 360, 1762, 1976, 1991, 2214], '3': [63, 259, 1763], '4.': [65, 261, 1850, 2241], 'Exons': [66, 262, 1959], '5': [67, 263, 1977], '7': [69, 265, 1979, 1992, 2026], 'encode': [70, 266], 'cysteine-rich': [71, 169, 267, 365, 1937, 1946], 'motifs': [72, 83, 268, 279, 3162], 'type': [75, 271], 'C6C10CRC,': [76, 272], 'exon': [78, 97, 274, 293, 1750, 1819, 1849, 1855, 2211, 2240, 2244, 2263, 3243], '6': [79, 275], 'encodes': [80, 276, 1858], 'additional': [81, 277], 'C10CXCXC': [82, 278], 'typical': [84, 280, 2622], 'silk': [87, 283, 1238, 4309], 'protein.': [88, 284, 1239, 2449, 4310], 'A': [89, 285, 1535, 1816, 2502], 'putative': [90, 133, 286, 329, 2582, 3052], 'alternatively': [91, 287, 1258, 1667, 1808, 2234, 2474, 4329], 'spliced': [92, 288, 1259, 1668, 1809, 2235, 2475, 4330], 'rare': [93, 289, 2486], 'RNA': [94, 290], 'form': [95, 291, 547, 2469, 3616], 'lacking': [96, 292, 2239], '4': [98, 294, 1765, 2212, 2245], 'was': [99, 111, 295, 307, 1074, 1391, 2333, 2505, 2843, 2933, 4145, 4463], 'identified': [100, 296], 'in': [101, 113, 171, 186, 297, 309, 367, 382, 413, 424, 645, 695, 705, 807, 841, 847, 898, 923, 958, 1691, 1735, 1761, 1784, 1810, 1822, 1844, 1866, 1874, 1950, 1990, 2092, 2248, 2344, 2404, 2478, 2496, 2635, 2845, 2905, 2911, 3008, 3163, 3241, 3256, 3261, 3482, 3493, 3714, 3764, 3774, 3877, 3911, 3917, 3968, 3993, 4028], 'fibrosarcoma': [103, 299], 'cells,': [104, 300, 2847], 'major': [107, 303, 2468, 3064], 'transcription': [108, 141, 304, 337, 1403, 1682, 2516, 2594, 2748, 2764, 2769, 2924, 4475], 'start': [109, 305, 2736], 'site': [110, 306, 1684, 2273, 2737, 2920], 'located': [112, 308, 2898], 'gene': [117, 158, 194, 313, 354, 390, 1299, 1543, 1610, 1661, 1710, 2095, 2521, 2542, 2571, 2961, 3047, 3074, 3211, 3251, 3269, 3439, 4371], '523': [118, 314, 2523], 'base': [119, 315, 489, 526, 3558, 3595], 'upstream': [121, 128, 317, 324, 2731], 'translation': [124, 320, 2735], 'initiation': [125, 321, 1683], 'codon.': [126, 322], 'promoter': [129, 150, 325, 346, 1300, 1390, 1487, 1546, 1603, 1689, 2572, 2830, 2902, 3048, 4372, 4462], 'sequences': [130, 326, 989, 1233, 1846, 2730, 3339, 4060, 4304], 'contain': [131, 327, 1394, 2269, 2444, 2741, 3051, 4466], 'conserved': [132, 328, 1000, 1783, 2289, 4071], 'binding': [134, 330, 1264, 1396, 1863, 2397, 2583, 2743, 2919, 3053, 4335, 4468], 'sites': [135, 331, 1397, 2398, 2584, 2744, 3001, 3054, 4469], 'Sp-1,': [137, 333, 1399, 2586, 4471], 'AP-2,': [138, 334], 'NF-κB': [140, 336, 2923, 2936, 3000, 3004], 'factors': [142, 338, 454, 631, 1404, 1705, 3523, 3700, 4476], 'but': [143, 339, 1830, 2343, 3219], 'no': [144, 340, 1962], 'TATA': [145, 341, 2575], 'box,': [146, 342], 'they': [148, 344], 'show': [149, 345, 1675, 1726, 1961, 2352], 'activity': [151, 347, 1073, 1547, 1690, 2831, 4144], 'when': [152, 348, 1076, 4147], 'transfected': [153, 349, 1692], 'into': [154, 350, 1956, 3335], 'cells.': [155, 351], 'structure': [159, 355, 1657, 1751, 2387, 3244], 'thus': [161, 357], 'assembled': [162, 358], 'from': [163, 359, 402, 708, 744, 1304, 2335, 2507, 2595, 3449, 3452, 3456, 3471, 3777, 3813, 4376], 'encoding': [165, 361, 1766], 'propeptides': [166, 362, 2110], 'distinct': [168, 184, 364, 380], 'domains': [170, 366, 2091], 'addition': [172, 368], 'to': [173, 369, 737, 1014, 1265, 1393, 1492, 1833, 1854, 1985, 2097, 2210, 2222, 2351, 2491, 2631, 2740, 2856, 2947, 3153, 3431, 3806, 4085, 4336, 4465], 'domain,': [177, 373, 1771], 'it': [179, 375, 907, 2580, 3977], 'shows': [180, 376], 'both': [181, 377], 'similarities': [182, 378, 1740], 'differences': [185, 381, 2137, 3240, 3255], 'comparison': [187, 383, 3262], 'with': [188, 384, 417, 1965, 2163, 2939, 3263, 3357, 3364, 3486], 'other': [189, 385, 628, 1734, 1756, 1812, 1828, 2142, 3458, 3697], 'members': [190, 386, 1243, 1813, 4314], 'VEGF/PDGF': [193, 389, 1241, 4312], 'process': [393, 3462], 'development': [397, 3466], 'new': [399, 3468], 'blood': [400, 700, 844, 3469, 3769, 3914], 'vessels': [401, 701, 855, 930, 3470, 3770, 3925, 4000], 'preexisting': [403, 3472], 'ones': [404, 3473], 'termed': [406, 3475], 'angiogenesis.': [407, 3476], 'Angiogenesis': [408, 3477], 'plays': [409, 3478], 'critical': [411, 3480], 'role': [412, 2634, 3481], 'providing': [414, 3483], 'growing': [415, 3484], 'tissues': [416, 810, 904, 925, 2464, 2500, 3485, 3880, 3974, 3995], 'oxygen': [418, 3487], 'nutrients': [420, 3489], 'also': [422, 633, 1604, 1615, 2112, 2934, 3212, 3252, 3491, 3702], 'occurs': [423, 3492], 'some': [425, 1739, 2098, 2849, 3494], 'pathological': [426, 3495], 'conditions,': [427, 3496], 'including': [428, 1495, 3497], 'tumor': [429, 1497, 3018, 3498], 'metastasis,': [432, 3501], 'inflammatory': [433, 2954, 3502], 'lesions,': [434, 3503], 'wound': [435, 3504], 'healing,': [436, 3505], 'endocrine': [438, 3507], 'diseases': [439, 3508], '(1Folkman': [440, 3509], 'J.': [441, 604, 657, 678, 719, 750, 753, 768, 814, 825, 865, 1040, 1063, 1094, 1099, 1154, 1182, 1210, 1277, 1318, 1348, 1372, 1416, 1446, 1470, 1519, 1556, 1584, 1626, 1890, 1918, 2011, 2030, 2171, 2175, 2316, 2372, 2417, 2557, 2652, 2675, 2696, 2789, 2795, 2870, 3031, 3092, 3131, 3189, 3309, 3510, 3673, 3726, 3747, 3788, 3819, 3822, 3837, 3884, 3895, 3935, 4111, 4134, 4165, 4170, 4225, 4253, 4281, 4348, 4390, 4420, 4444, 4488, 4518], 'Nature': [442, 3511], 'Medicine.': [443, 3512], '1995;': [444, 606, 659, 886, 1321, 1419, 1559, 3095, 3513, 3675, 3728, 3956, 4393, 4491], '1:': [445, 3514], '27-31Crossref': [446, 3515], 'PubMed': [447, 565, 590, 622, 687, 762, 778, 831, 889, 983, 1049, 1067, 1108, 1158, 1186, 1214, 1288, 1329, 1357, 1383, 1427, 1455, 1481, 1530, 1567, 1595, 1637, 1899, 1929, 2020, 2048, 2082, 2130, 2192, 2320, 2432, 2566, 2609, 2661, 2686, 2701, 2723, 2783, 2799, 2817, 2887, 2976, 2992, 3103, 3120, 3142, 3178, 3200, 3293, 3326, 3385, 3516, 3634, 3659, 3691, 3756, 3831, 3847, 3901, 3959, 4053, 4120, 4138, 4179, 4229, 4257, 4285, 4359, 4401, 4429, 4455, 4499], 'Scopus': [448, 566, 591, 623, 779, 832, 890, 984, 1068, 1159, 1187, 1215, 1289, 1330, 1384, 1428, 1482, 1531, 1568, 1596, 1638, 1930, 2049, 2083, 2131, 2193, 2321, 2433, 2610, 2687, 2702, 2724, 2784, 2800, 2818, 2888, 2977, 2993, 3104, 3121, 3143, 3179, 3201, 3294, 3327, 3386, 3517, 3635, 3660, 3692, 3848, 3902, 3960, 4054, 4139, 4230, 4258, 4286, 4360, 4402, 4456, 4500], '(7176)': [449, 3518], 'Google': [450, 568, 593, 609, 625, 662, 688, 730, 763, 781, 834, 892, 949, 986, 1050, 1070, 1109, 1161, 1189, 1217, 1291, 1332, 1358, 1386, 1430, 1456, 1484, 1533, 1570, 1598, 1640, 1900, 1932, 2021, 2051, 2085, 2133, 2195, 2323, 2435, 2567, 2612, 2662, 2689, 2704, 2726, 2786, 2802, 2820, 2890, 2979, 2995, 3106, 3123, 3145, 3181, 3203, 3296, 3329, 3388, 3414, 3519, 3637, 3662, 3678, 3694, 3731, 3757, 3799, 3832, 3850, 3904, 3962, 4019, 4056, 4121, 4141, 4180, 4232, 4260, 4288, 4362, 4404, 4430, 4458, 4502], 'Scholar).': [451, 626, 689, 731, 835, 893, 1110, 1218, 1387, 1485, 1534, 1599, 2086, 2324, 2436, 2727, 2821, 2891, 2996, 3146, 3204, 3330, 3415, 3520, 3695, 3758, 3800, 3851, 3905, 3963, 4057, 4181, 4289, 4363, 4459], 'Specific': [452, 3521], 'endothelium,': [458, 3527], 'namely': [459, 3528], '(VEGF),': [464, 3533], '1The': [465, 3534], 'abbreviations': [466, 503, 3535, 3572], 'used': [467, 504, 2904, 3536, 3573], 'are:': [468, 505, 3537, 3574], 'VEGF,': [469, 506, 1722, 1966, 3538, 3575], 'factor;': [473, 477, 481, 510, 514, 518, 3542, 3546, 3550, 3579, 3583, 3587], 'PlGF,': [474, 511, 3543, 3580], 'placenta': [475, 512, 543, 3544, 3581, 3612], 'PDGF,': [478, 515, 1007, 3547, 3584, 4078], 'platelet-derived': [479, 516, 552, 3548, 3585, 3621], 'VEGFR,': [482, 519, 3551, 3588], 'receptor;': [487, 524, 3556, 3593], 'bp,': [488, 525, 3557, 3594], 'pair(s);': [490, 493, 527, 530, 3559, 3562, 3596, 3599], 'kb,': [491, 528, 3560, 3597], 'PCR,': [494, 531, 3563, 3600], 'polymerase': [495, 532, 3564, 3601], 'chain': [496, 501, 533, 538, 3565, 3570, 3602, 3607], 'reaction;': [497, 534, 3566, 3603], 'RT-PCR,': [498, 535, 3567, 3604], 'reverse': [499, 536, 3568, 3605], 'transcriptase-polymerase': [500, 537, 3569, 3606], 'reaction.1The': [502, 3571], 'reaction.': [539, 3608], 'VEGF-B,': [540, 1723, 3609], 'VEGF-C,': [541, 1748, 1944, 3610], '(PlGF)': [546, 3615], 'subfamily': [549, 1701, 3618], 'family': [555, 995, 1242, 1758, 1787, 3270, 3624, 4066, 4313], '(2Ferrara': [556, 3625], 'N.': [557, 673, 1178, 1206, 2312, 3626, 3742, 4249, 4277], 'Davis-Smyth': [558, 3627], 'T.': [559, 577, 669, 725, 867, 1090, 1152, 1194, 1339, 1437, 1881, 1905, 2002, 2548, 2643, 3628, 3646, 3738, 3794, 3937, 4161, 4223, 4265, 4411, 4509], 'Endocr.': [560, 3629], 'Rev.': [561, 618, 3174, 3630, 3687], '1997;': [562, 980, 1155, 1211, 1921, 2429, 2796, 2884, 3290, 3323, 3631, 4050, 4226, 4282], '18:': [563, 3632], '4-25Crossref': [564, 3633], '(3668)': [567, 3636], 'Scholar,': [569, 594, 610, 663, 764, 1051, 1162, 1190, 1333, 1359, 1431, 1457, 1571, 1901, 2690, 2705, 2787, 2803, 2980, 3107, 3124, 3182, 3297, 3389, 3638, 3663, 3679, 3732, 3833, 4122, 4233, 4261, 4405, 4431, 4503], '3Neufeld': [570, 3639], 'G.': [571, 1031, 1144, 1274, 1911, 1917, 2038, 2059, 3395, 3409, 3640, 4102, 4215, 4345], 'Tessler': [572, 3641], 'S.': [573, 884, 936, 1146, 1150, 1270, 1315, 1413, 1512, 1553, 2034, 2077, 2187, 2368, 2427, 2793, 3027, 3089, 3374, 3380, 3642, 3954, 4006, 4217, 4221, 4341, 4387, 4485], 'Gitay-Goren': [574, 3643], 'H.': [575, 715, 972, 1272, 1510, 2179, 2415, 2709, 3282, 3644, 3784, 4042, 4343], 'Cohen': [576, 1904, 3645], 'Levi': [578, 3647], 'B.-Z.': [579, 3648], 'Prog.': [580, 3649], 'Growth': [581, 616, 3172, 3650, 3685], 'Factor': [582, 617, 3173, 3651, 3686], 'Res.': [583, 2043, 3652], '1994;': [584, 681, 1102, 3653, 3750, 4173], '5:': [585, 2125, 3654], '89-97Abstract': [586, 3655], 'Full': [587, 684, 759, 773, 775, 1046, 1105, 1283, 1285, 1324, 1326, 1354, 1378, 1380, 1422, 1424, 1452, 1476, 1478, 1525, 1527, 1562, 1564, 1590, 1592, 1632, 1634, 1896, 1924, 1926, 2017, 2127, 2563, 2606, 2658, 2681, 2683, 2780, 2814, 2971, 2973, 2989, 3098, 3100, 3137, 3139, 3195, 3197, 3656, 3753, 3828, 3842, 3844, 4117, 4176, 4354, 4356, 4396, 4398, 4426, 4450, 4452, 4494, 4496], 'Text': [588, 685, 760, 774, 776, 1047, 1106, 1284, 1286, 1325, 1327, 1355, 1379, 1381, 1423, 1425, 1453, 1477, 1479, 1526, 1528, 1563, 1565, 1591, 1593, 1633, 1635, 1897, 1925, 1927, 2018, 2128, 2564, 2607, 2659, 2682, 2684, 2781, 2815, 2972, 2974, 2990, 3099, 3101, 3138, 3140, 3196, 3198, 3657, 3754, 3829, 3843, 3845, 4118, 4177, 4355, 4357, 4397, 4399, 4427, 4451, 4453, 4495, 4497], 'PDF': [589, 686, 761, 777, 1048, 1107, 1287, 1328, 1356, 1382, 1426, 1454, 1480, 1529, 1566, 1594, 1636, 1898, 1928, 2019, 2129, 2565, 2608, 2660, 2685, 2782, 2816, 2975, 2991, 3102, 3141, 3199, 3658, 3755, 3830, 3846, 4119, 4178, 4358, 4400, 4428, 4454, 4498], '(210)': [592, 3661], '4Dvorak': [595, 3664], 'H.F.': [596, 649, 3665, 3718], 'Brown': [597, 650, 3666, 3719], 'L.F.': [598, 651, 3667, 3720], 'Detmar': [599, 652, 3668, 3721], 'M.': [600, 612, 653, 876, 940, 962, 970, 1027, 1061, 1086, 1198, 1276, 1341, 1363, 1439, 1461, 1506, 1508, 1518, 1575, 1883, 2004, 2036, 2370, 2550, 2645, 2666, 2771, 2775, 2874, 3029, 3168, 3272, 3280, 3313, 3368, 3669, 3681, 3722, 3946, 4010, 4032, 4040, 4098, 4132, 4157, 4269, 4347, 4413, 4435, 4511], 'Dvorak': [601, 654, 3670, 3723], 'A.M.': [602, 655, 3671, 3724], 'Am.': [603, 656, 3672, 3725], 'Pathol.': [605, 658, 3674, 3727], '146:': [607, 660, 3676, 3729], '1029-1039PubMed': [608, 661, 3677, 3730], '5Klagsburn': [611, 3680], "D'Amore": [613, 1370, 1468, 1582, 2673, 3169, 3682, 4442], 'P.A.': [614, 1371, 1469, 1583, 2674, 2964, 3170, 3683, 4443], 'Cytokine': [615, 3171, 3684], '1996;': [619, 770, 946, 1183, 1280, 1375, 1473, 1522, 1587, 1629, 2045, 2079, 2189, 2317, 2678, 2968, 3134, 3175, 3192, 3382, 3688, 3839, 4016, 4254, 4351, 4447], '7:': [620, 3176, 3689], '259-270Crossref': [621, 3177, 3690], '(401)': [624, 3180, 3693], 'Certain': [627, 3696], 'angiogenic': [629, 3698], 'may': [632, 1982, 2483, 2896, 3005, 3701], 'act': [634, 3703], 'indirectly': [635, 3704], 'on': [636, 3705], 'cells': [638, 647, 711, 745, 2459, 2498, 3707, 3716, 3780, 3814], 'via': [639, 1137, 1617, 3708, 4208], 'induction': [641, 1611, 3010, 3070, 3710], 'secretion': [644, 3713], 'adjacent': [646, 3715], '(4Dvorak': [648, 3717], '6Pertovaara': [664, 3733], 'L.': [665, 1200, 2872, 3311, 3370, 3734, 4271], 'Kaipainen': [666, 937, 963, 1167, 2056, 2301, 3273, 3735, 4007, 4033, 4238], 'A.': [667, 671, 812, 863, 885, 934, 938, 964, 1029, 1055, 1168, 2057, 2065, 2078, 2173, 2188, 2302, 2374, 2421, 2428, 2864, 3033, 3111, 3274, 3303, 3381, 3736, 3740, 3882, 3933, 3955, 4004, 4008, 4034, 4100, 4126, 4239], 'Mustonen': [668, 866, 3737, 3936], 'Orpana': [670, 2064, 3739], 'Ferrara': [672, 3741], 'Saksela': [674, 1175, 1203, 2062, 2309, 3743, 4246, 4274], 'O.': [675, 818, 1176, 1204, 2063, 2310, 3399, 3744, 3888, 4247, 4275], 'Alitalo': [676, 823, 877, 943, 977, 1179, 1207, 2068, 2313, 2881, 3287, 3320, 3400, 3745, 3893, 3947, 4013, 4047, 4250, 4278], 'K.': [677, 816, 824, 878, 944, 978, 1166, 1180, 1208, 1516, 2055, 2069, 2300, 2314, 2713, 2862, 2882, 3288, 3301, 3321, 3401, 3746, 3886, 3894, 3948, 4014, 4048, 4237, 4251, 4279], 'Biol.': [679, 754, 1041, 1100, 1278, 1319, 1349, 1373, 1417, 1447, 1471, 1520, 1557, 1585, 1627, 1891, 1919, 2012, 2558, 2653, 2676, 3093, 3132, 3190, 3748, 3823, 4112, 4171, 4349, 4391, 4421, 4445, 4489, 4519], 'Chem.': [680, 755, 1042, 1101, 1279, 1320, 1350, 1374, 1418, 1448, 1472, 1521, 1558, 1586, 1628, 1892, 1920, 2013, 2559, 2654, 2677, 3094, 3133, 3191, 3749, 3824, 4113, 4172, 4350, 4392, 4422, 4446, 4490, 4520], '269:': [682, 1103, 3751, 4174], '6271-6274Abstract': [683, 3752], 'Besides': [690, 3759], 'angiogenesis,': [691, 3760], 'implicated': [694, 3007, 3763], 'vasculogenesis': [696, 733, 3765, 3802], 'or': [697, 2206, 2213, 3766], 'formation': [698, 3767], 'de': [702, 3771], 'novo': [703, 3772], 'situ': [706, 783, 3775, 3853], 'differentiation': [707, 3776], 'mesodermal': [709, 3778], 'precursor': [710, 1127, 1225, 2281, 3779, 4198, 4296], '(7Risau': [712, 3781], 'W.': [713, 3782], 'Sariola': [714, 3783], 'Zerwes': [716, 3785], 'H.-G.': [717, 3786], 'Sasse': [718, 3787], 'Ekblom': [720, 3789], 'P.': [721, 3790], 'Kemler': [722, 3791], 'R.': [723, 976, 1148, 1337, 1435, 1879, 1907, 2000, 2067, 2546, 2601, 2641, 2773, 2791, 2809, 3286, 3372, 3792, 4046, 4219, 4409, 4507], 'Doetschman': [724, 3793], 'Development.': [726, 945, 3795, 4015], '1988;': [727, 2698, 3796], '102:': [728, 3797], '471-478PubMed': [729, 3798], 'angiogenesis': [735, 3804], 'appear': [736, 3805], 'be': [738, 1015, 1983, 2223, 2854, 2897, 2948, 3006, 3154, 3807, 4086], 'further': [739, 1138, 3808, 4209], 'regulated': [740, 3809], 'inhibitory': [742, 3811], 'signals': [743, 3812], 'pericellular': [747, 3816], 'matrices': [748, 3817], '(8Folkman': [749, 3818], 'Shing': [751, 3820], 'Y.': [752, 1202, 1909, 2411, 2868, 3307, 3821, 4273], '1992;': [756, 1043, 1064, 3117, 3825, 4114, 4135], '267:': [757, 1044, 3826, 4115], '10931-10934Abstract': [758, 3827], '9Hanahan': [765, 3834], 'D.': [766, 874, 1170, 1343, 1441, 1885, 2006, 2304, 2552, 2647, 2692, 2966, 2984, 3023, 3109, 3113, 3391, 3835, 3944, 4241, 4415, 4513], 'Folkman': [767, 3836], 'Cell.': [769, 2602, 2776, 2810, 2967, 2985, 3838], '86:': [771, 3840], '353-364Abstract': [772, 3841], '(6016)': [780, 3849], 'Scholar).In': [782], 'hybridization': [784, 2154, 3854], 'studies': [785, 3059, 3855], 'have': [786, 800, 1011, 1245, 1935, 2151, 2348, 2388, 2492, 2632, 2824, 3060, 3432, 3447, 3856, 3870, 4082, 4316], 'revealed': [787, 3857], 'that': [788, 906, 1676, 1753, 2100, 2353, 2390, 2454, 2488, 2591, 2752, 2827, 3003, 3062, 3226, 3858, 3976], 'three': [790, 1957, 3860], 'receptors': [792, 3862], 'VEGFR-1': [793, 3863], '(Flt-1),': [794, 3864], 'VEGFR-2': [795, 3865], '(Flk-1/KDR),': [796, 3866], 'VEGFR-3': [798, 836, 3868, 3906], '(Flt4)': [799, 3869], 'specific,': [801, 3871], 'although': [802, 1072, 1601, 1967, 2848, 3872, 4143], 'partly': [803, 3873], 'overlapping,': [804, 3874], 'expression': [805, 837, 896, 917, 2962, 3875, 3907, 3966, 3987], 'patterns': [806, 3876], 'developing': [808, 853, 928, 3878, 3923, 3998], 'fetal': [809, 3879], '(10Kaipainen': [811, 3881], 'Korhonen': [813, 864, 3883, 3934], 'Pajusola': [815, 1165, 2054, 2299, 3885, 4236], 'Aprelikova': [817, 3398, 3887], 'Persico': [819, 3408, 3889], 'M.G.': [820, 3397, 3890], 'Terman': [821, 3891], 'B.I.': [822, 3892], 'Exp.': [826, 3896], 'Med.': [827, 3897], '1993;': [828, 3411, 3898], '178:': [829, 3899], '2077-2088Crossref': [830, 3900], '(215)': [833, 3903], 'has': [838, 1301, 1605, 1662, 2533, 2581, 3253, 3908, 4373], 'been': [839, 1012, 1302, 1663, 2349, 3909, 4083, 4374], 'localized': [840, 3910], 'early': [842, 3912], 'embryonic': [843, 860, 3913, 3930], 'vessels,': [845, 3915], 'especially': [846, 3916], 'regions': [848, 1798, 3918], 'where': [849, 2105, 3919], 'sprouting': [851, 3921], 'lymphatic': [854, 900, 929, 956, 3924, 3970, 3999, 4026], 'takes': [856, 3926], 'place': [857, 3927], 'during': [858, 3459, 3928], 'period': [861, 3931], '(11Kaipainen': [862, 3932], 'van': [868, 3938], 'Hinsbergh': [869, 3939], 'V.W.M.': [870, 3940], 'Fang': [871, 3941], 'G.-H.': [872, 3942], 'Dumont': [873, 3943], 'Breitman': [875, 3945], 'Proc.': [879, 2072, 2182, 2422, 2716, 3375, 3949], 'Natl.': [880, 2073, 2183, 2423, 2717, 3376, 3950], 'Acad.': [881, 2074, 2184, 2424, 2718, 3377, 3951], 'Sci.': [882, 2075, 2185, 2425, 2719, 3378, 3952], 'U.': [883, 1033, 1365, 1463, 1577, 2071, 2076, 2186, 2426, 2668, 2880, 3319, 3379, 3953, 4104, 4437], '92:': [887, 3957], '3566-3570Crossref': [888, 3958], '(1174)': [891, 3961], 'Its': [894, 3964], 'continued': [895, 3965], 'primarily': [897, 3967], 'endothelium': [901, 3971], 'adult': [903, 3973], 'suggests': [905, 2751, 3002, 3975], 'functions': [908, 3978], 'as': [909, 2460, 2462, 2759, 3979], 'regulator': [911, 3981], 'these': [913, 1794, 3983], 'vessels.': [914, 3984], 'Notably,': [915, 3985], 'often': [921, 3991], 'found': [922, 2739, 3992], 'mesenchymal': [924, 3994], 'surrounding': [926, 3996], '(12Kukk': [931, 4001], 'E.': [932, 1174, 1335, 1433, 1877, 1915, 1998, 2308, 2366, 2544, 2639, 3025, 3115, 4002, 4245, 4407, 4505], 'Lymboussaki': [933, 4003], 'Taira': [935, 4005], 'Jeltsch': [939, 1197, 4009, 4268], 'Joukov': [941, 965, 2060, 2877, 3275, 3316, 4011, 4035], 'V.': [942, 966, 1164, 1192, 1196, 2061, 2298, 2376, 2866, 2878, 3035, 3276, 3305, 3317, 3393, 4012, 4036, 4235, 4263, 4267], '122:': [947, 4017], '3829-3837PubMed': [948, 4018], 'Scholar),': [950, 1071, 2568, 4020, 4142], 'overexpression': [952, 4022], 'induces': [955, 4025], 'hyperplasia': [957, 4027], 'transgenic': [959, 4029], 'mice': [960, 4030], '(13Jeltsch': [961, 3271, 4031], 'Meng': [967, 3277, 4037], 'X.': [968, 3278, 4038], 'Lakso': [969, 3279, 4039], 'Rauvala': [971, 3281, 4041], 'Swartz': [973, 3283, 4043], 'M.D.F.': [974, 3284, 4044], 'Jain': [975, 3285, 4045], 'Science.': [979, 3289, 4049], '276:': [981, 3291, 4051], '1423-1425Crossref': [982, 3292, 4052], '(1103)': [985, 3295, 4055], 'Scholar).Amino': [987], 'acid': [988, 1252, 3338, 3423, 4059, 4323], 'PDGF/VEGF': [992, 1786, 4063], 'are': [996, 1255, 1685, 1796, 1807, 1973, 2111, 3231, 3345, 3429, 4067, 4326], 'distinguished': [997, 4068], 'eight': [999, 1775, 4070], 'cysteine': [1001, 1009, 1231, 1776, 1970, 2401, 4072, 4080, 4302], 'residues.': [1002, 4073], 'In': [1003, 1219, 1744, 1940, 2728, 3852, 4074, 4290], 'case': [1005, 1746, 1942, 4076], 'residues': [1010, 1129, 1777, 2291, 2402, 4081, 4200], 'shown': [1013, 1392, 2153, 2389, 2825, 3061, 4084, 4464], 'essential': [1016, 2400, 4087], 'correct': [1019, 4090], 'folding': [1020, 4091], 'dimerization': [1022, 4093], 'protein': [1025, 2266, 2328, 2355, 2590, 2755, 3247, 4096], '(14Andersson': [1026, 4097], 'Östman': [1028, 4099], 'Bäckström': [1030, 4101], 'Hellman': [1032, 4103], 'George-Nascimento': [1034, 4105], 'C.': [1035, 1053, 2032, 2807, 4106, 4124], 'Westermark': [1036, 2120, 4107], 'B.': [1037, 1059, 2053, 2121, 2413, 2419, 2860, 2876, 3299, 3315, 4108, 4130], 'Heldin': [1038, 4109], 'C.-H.': [1039, 2119, 4110], '11260-11266Abstract': [1045, 4116], '15Oefner': [1052, 4123], 'DArcy': [1054, 4125], 'Winkler': [1056, 4127], 'F.K.': [1057, 4128], 'Eggimann': [1058, 4129], 'Hosang': [1060, 4131], 'EMBO': [1062, 1181, 1209, 2315, 2794, 4133, 4252, 4280], '11:': [1065, 1156, 4136, 4227], '3921-3926Crossref': [1066, 4137], '(185)': [1069, 4140], 'preserved': [1075, 4146], 'interchain': [1078, 4149], 'disulfide': [1079, 2408, 4150], 'bonds': [1080, 4151], 'were': [1081, 2220, 2738, 4152], 'mutated': [1082, 4153], '(16Kenney': [1083, 4154], 'W.C.': [1084, 4155], 'Haniu': [1085, 4156], 'Herman': [1087, 4158], 'A.C.': [1088, 4159], 'Arakawa': [1089, 4160], 'Costigan': [1091, 4162], 'V.J.': [1092, 4163], 'Lary': [1093, 4164], 'Yphantis': [1095, 4166], 'D.A.': [1096, 4167], 'Thomason': [1097, 4168], 'A.R.': [1098, 4169], '12351-12359Abstract': [1104, 4175], 'dimers': [1113, 4184], 'polypeptides': [1116, 4187], '29-': [1118, 4189], '31-kDa,': [1120, 4191], 'generated': [1121, 4192], 'proteolytic': [1123, 4194], 'cleavage': [1124, 2272, 4195], 'between': [1128, 1732, 2138, 4199], '227': [1130, 2276, 4201], '228,': [1132, 4203], '21': [1134, 4205], 'kDa,': [1135, 4206], 'produced': [1136, 2334, 4207], 'N-terminal': [1139, 4210], 'cleavages': [1140, 4211], '(17Hu': [1141, 4212], 'J.-S.': [1142, 4213], 'Hastings': [1143, 4214], 'Cherry': [1145, 4216], 'Gentz': [1147, 4218], 'Ruben': [1149, 4220], 'Coleman': [1151, 4222], 'FASEB': [1153, 4224], '498-504Crossref': [1157, 4228], '(19)': [1160, 4231], '18Joukov': [1163, 4234], 'Chilov': [1169, 2303, 4240], 'Lahtien': [1171, 2305, 4242], 'I.': [1172, 1913, 2306, 4243], 'Kukk': [1173, 2307, 4244], 'Kalkkinen': [1177, 1205, 2311, 4248, 4276], '15:': [1184, 2318, 4255], '290-298Crossref': [1185, 2319, 4256], '(1143)': [1188, 2322, 4259], '19Joukov': [1191, 4262], 'Sorsa': [1193, 4264], 'Kumar': [1195, 2865, 3304, 4266], 'Claesson-Welsh': [1199, 4270], 'Cao': [1201, 4272], '16:': [1212, 2797, 4283], '3898-3911Crossref': [1213, 4284], '(638)': [1216, 4287], 'its': [1220, 3164, 3242, 3257, 4291], 'terminus,': [1222, 4293], 'contains': [1226, 1544, 1773, 2394, 3213, 4297], 'unique': [1228, 4299], 'rich': [1232, 4303], 'resembling': [1234, 4305], 'those': [1235, 4306], 'Other': [1240, 4311], 'typically': [1244, 4315], 'short': [1246, 1817, 4317], 'C-terminal': [1247, 1842, 2109, 2271, 4318], 'stretches': [1248, 4319], 'basic': [1250, 1501, 4321], 'amino': [1251, 3337, 3422, 4322], 'residues,': [1253, 4324], 'which': [1254, 1772, 1806, 1857, 1972, 2620, 4325], 'mRNAs': [1260, 4331], 'mediate': [1262, 4333], 'heparan': [1266, 4337], 'sulfate': [1267, 4338], 'proteoglycans': [1268, 4339], '(20Soker': [1269, 4340], 'Fidder': [1271, 4342], 'Neufeld': [1273, 1916, 4344], 'Klagsbrun': [1275, 4346], '271:': [1281, 1376, 1474, 1523, 1588, 1630, 2679, 3135, 3193, 4352, 4448], '5761-5767Abstract': [1282, 4353], '(287)': [1290, 4361], 'Scholar).The': [1292, 2134], 'isolation': [1293, 4365], 'reported': [1303, 2197, 4375], 'human,': [1305, 4377], 'rat,': [1306, 4378], 'species': [1309, 2157, 4381], '(21Levy': [1310, 1408, 1548, 3084, 4382, 4480], 'A.P.': [1311, 1369, 1409, 1467, 1549, 1581, 1621, 2672, 3085, 3126, 3184, 4383, 4441, 4481], 'Levy': [1312, 1410, 1550, 1622, 3086, 3127, 3185, 4384, 4482], 'N.S.': [1313, 1411, 1551, 1623, 3087, 3128, 3186, 4385, 4483], 'Wegner': [1314, 1412, 1552, 3088, 4386, 4484], 'Goldberg': [1316, 1414, 1554, 1624, 3090, 3129, 3187, 4388, 4486], 'M.A.': [1317, 1415, 1555, 1625, 3091, 3130, 3188, 4389, 4487], '270:': [1322, 1420, 1560, 3096, 4394, 4492], '13333-13340Abstract': [1323, 1421, 1561, 3097, 4395, 4493], '(876)': [1331, 1429, 1569, 3105, 4403, 4501], '22Tischer': [1334, 1432, 4406, 4504], 'Mitchell': [1336, 1434, 1878, 1999, 2545, 2640, 4408, 4506], 'Hartman': [1338, 1436, 1880, 2001, 2547, 2642, 4410, 4508], 'Silva': [1340, 1438, 1882, 2003, 2549, 2644, 4412, 4510], 'Gospodarowicz': [1342, 1440, 1884, 2005, 2551, 2646, 4414, 4512], 'Fiddes': [1344, 1442, 1886, 2007, 2553, 2648, 4416, 4514], 'J.C.': [1345, 1443, 1887, 2008, 2554, 2649, 4417, 4515], 'Abraham': [1346, 1444, 1888, 2009, 2555, 2650, 4418, 4516], 'J.A.': [1347, 1445, 1889, 2010, 2556, 2651, 4419, 4517], '1991;': [1351, 1449, 1893, 2014, 2560, 2655, 4423, 4521], '266:': [1352, 1450, 1894, 2015, 2561, 2656, 4424, 4522], '11947-11954Abstract': [1353, 1451, 1895, 2016, 2562, 2657, 4425, 4523], '23Shima': [1360, 1458, 1572, 4432], 'D.T.': [1361, 1459, 1573, 2664, 4433], 'Kuroki': [1362, 1460, 1574, 2665, 4434], 'Deutsch': [1364, 1462, 1576, 2667, 4436], 'Ng': [1366, 1464, 1578, 2669, 4438], 'Y.-S.': [1367, 1465, 1579, 2670, 4439], 'Adamis': [1368, 1466, 1580, 2671, 4440], '3877-3883Abstract': [1377, 1475, 1589, 2680, 4449], '(310)': [1385, 1483, 1597, 2688, 4457], 'multiple': [1395, 3421, 4467], 'AP-1,': [1400, 4472], 'AP-2': [1402, 2747, 2763, 4474], 'hypoxia-regulated': [1406, 1607, 3056, 4478], 'elements': [1407, 2895, 4479], 'This': [1486, 2265, 2750], 'TATA-less': [1489, 2596], 'responds': [1491], 'various': [1493], 'effectors,': [1494], 'hypoxia,': [1496], 'necrosis': [1498, 3019], 'factor-α,': [1499], 'fibroblast': [1502], '(24Ryuto': [1505], 'Ono': [1507], 'Izumi': [1509], 'Yoshida': [1511], 'Weich': [1513], 'H.A.': [1514], 'Kohno': [1515], 'Kuwano': [1517], '28220-28228Abstract': [1524], '(452)': [1532], '1.2-kb': [1536], '5′-flanking': [1537], 'region': [1538, 2393, 3166, 3207], 'basal': [1545, 1688], 'However,': [1600], 'element,': [1608], 'hypoxia': [1613], 'effected': [1616], 'mRNA': [1618, 1670, 2156, 2476, 2532, 2841, 2857, 3014, 3083, 3149, 3228], 'stabilization': [1619, 2858], '(25Levy': [1620], '25492-25497Abstract': [1631, 3194], '(205)': [1639, 3202], 'Scholar).We': [1641], 'genes.': [1654], 'analyzed,': [1664], 'one': [1666, 2467], 'isoform': [1671], 'described.': [1673], 'fragments': [1679, 2903], 'sufficient': [1686], 'cells.DISCUSSIONVEGF-C': [1693], 'fourth': [1696], 'PDGF-related': [1703], 'largest': [1708], 'described': [1711, 1720, 2442], 'so': [1712], 'far.': [1713], 'structures': [1716], 'previously': [1719, 2152], 'members,': [1721, 1759], 'PlGF': [1725, 3453], 'high': [1728], 'degree': [1729], 'similarity': [1731], 'each': [1733, 3457], 'exon-intron': [1736], 'junctions': [1737], 'alternative': [1742, 2147, 2227, 2259], 'splicing.': [1743, 2228], 'resembles': [1752, 2096], 'particularly': [1760], 'core': [1768], 'signature': [1780], 'sequence': [1781, 1852, 3161, 3424], 'PXCVXXXRCXGCC': [1782], 'members.': [1788], 'most': [1790, 2135], 'variable': [1791], 'parts': [1792], 'sixth': [1802], 'seventh': [1804], 'except': [1814], 'VEGF-C.': [1815, 2471], 'fifth': [1818], 'present': [1821, 1865, 2907], 'splicing': [1824, 2148], 'variants': [1825], 'genes,': [1829], 'appears': [1832], 'lack': [1834, 2284], 'such': [1835], 'an': [1836], 'exon.': [1837], 'Instead,': [1838, 2579], 'there': [1839], 'extension': [1843], 'Also,': [1851], 'corresponding': [1853, 2209, 2392, 2840], '6,': [1856], 'part': [1859, 2446], 'heparin': [1862], 'VEGF145,': [1867], 'VEGF165,': [1868], 'VEGF189,': [1869], 'PlGF152': [1871], 'missing': [1873], '(22Tischer': [1876, 1997, 2543, 2638], '33Poltorak': [1902], 'Z.': [1903], 'Sivan': [1906], 'Kandelis': [1908], 'Spira': [1910], 'Vlodavsky': [1912], 'Keshet': [1914, 3114], '272:': [1922], '7151-7158Abstract': [1923], '(447)': [1931], 'Scholar).All': [1933], 'VEGFs': [1934, 2143, 2441], 'terminus.': [1939], 'extended': [1949], 'repeated': [1952], 'motif': [1953, 3215], 'divided': [1955], 'exons.': [1958], '5–7': [1960], 'significant': [1963, 2493, 3239], 'C6C10CRC': [1969], 'motifs,': [1971], 'related': [1984], 'CXCXC6C11CRC': [1987], 'pattern': [1988], 'distributed': [1989], '8': [1994, 2288], 'Scholar)': [2022, 2196, 2613], '6A': [2024], 'VEGF-B': [2028], '(34Lagercrantz': [2029], 'Larsson': [2031], 'Grimmond': [2033], 'Fredriksson': [2035], 'Weber': [2037], 'Piehl': [2039], 'F.': [2040], 'Biochem.': [2041, 2697], 'Biophys.': [2042], 'Commun.': [2044], '220:': [2046], '147-152Crossref': [2047], '(21)': [2050], 'Scholar,35Olofsson': [2052], 'Euler': [2058], 'Pettersson': [2066], 'Eriksson': [2070, 2879, 3318], '93:': [2080, 2190, 3383], '2576-2581Crossref': [2081], '(619)': [2084], 'distribution': [2088], 'functional': [2090, 3436], 'extent': [2099], 'PDGF-B': [2103], 'gene,': [2104, 3044], 'N-': [2107], 'cleaved': [2113], 'off': [2114], 'after': [2115, 2257], 'polypeptide': [2116], 'biosynthesis': [2117], '(36Heldin': [2118], 'Trends': [2122], 'Genet.': [2123], '1989;': [2124, 2986], '108-111Abstract': [2126], '(130)': [2132], 'striking': [2136], 'concern': [2144], 'potential': [2146], 'variants.': [2149], '2.4': [2159], '2.0–2.2': [2161], 'kb': [2162], 'probe.': [2166], 'Lee': [2167], 'et': [2168], 'al.': [2169], '(37Lee': [2170], 'Gray': [2172], 'Yuan': [2174], 'Luoh': [2176], 'S.-M.': [2177], 'Avraham': [2178], 'Wood': [2180], 'W.I.': [2181], '1988-1992Crossref': [2191], '(329)': [2194], 'two': [2198], 'cDNA': [2200], 'clones': [2201], 'deletions': [2203], '152': [2205], '557': [2207], 'nucleotides': [2208], '2–4,': [2215], 'respectively.': [2216], 'These': [2217], 'variant': [2218, 2341], 'cDNAs': [2219], 'considered': [2221, 3152], 'result': [2225, 2247], 'similar,': [2233], 'version': [2236], 'Deletion': [2242], 'would': [2246, 2267, 2283], 'premature': [2250], 'stop': [2251], 'codon': [2252], 'caused': [2253], 'frameshift': [2256], 'splice': [2260], 'acceptor': [2261], '5.': [2264], 'not': [2268, 3050, 3232], '(amino': [2274], 'acids': [2275], '228)': [2278], '2': [2285], 'Cys': [2290], '(18Joukov': [2297], 'Indeed,': [2325], 'recombinant': [2327], 'expected': [2331], 'size': [2332], 'baculovirus': [2337], 'vector': [2338], 'cDNA,': [2342], 'preliminary': [2345, 3223], 'experiments,': [2346], 'we': [2347, 2823], 'unable': [2350], 'this': [2354, 2445, 2851, 2916, 3217, 3268], 'capable': [2357], 'stimulating': [2359], 'autophosphorylation': [2361], 'VEGFR-3.': [2363], '2D.': [2364], 'Chilov,': [2365, 3024], 'Kukk,': [2367, 3026], 'Taira,': [2369, 3028], 'Jeltsch,': [2371, 3030], 'Kaukonen,': [2373, 3032], 'Palotie,': [2375, 3034], 'Joukov,': [2377, 3036], 'Kari': [2379, 3038], 'Alitalo,': [2380, 3039], 'unpublished': [2381, 3040], 'data.': [2382], 'Studies': [2383], 'crystal': [2386], 'receptor': [2396], 'involved': [2403], 'inter-': [2405], 'intrachain': [2407], 'bonding': [2409], '(38Muller': [2410], 'Li': [2412], 'Christinger': [2414], 'Wels': [2416], 'Cunningham': [2418], 'Devos': [2420], '94:': [2430], '7192-7197Crossref': [2431], '(363)': [2434], 'All': [2437], 'isoforms': [2438], 'earlier': [2443, 3454], 'Furthermore,': [2450], 'RT-PCR': [2451, 2508], 'analysis': [2452, 2509], 'suggested': [2453], 'PC-3': [2456], 'HT-1080': [2458, 2480], 'well': [2461], 'several': [2463, 2624], 'express': [2465], 'only': [2466], 'Therefore,': [2472], 'detected': [2477], 'cell': [2481], 'library': [2482], 'represent': [2484], 'transcript': [2487], 'unlikely': [2490], 'biological': [2494], 'relevance': [2495], 'analyzed.': [2501], 'similar': [2503, 3433], 'conclusion': [2504], 'made': [2506], 'region.The': [2515], 'starts': [2522], 'bp': [2524], 'before': [2525], 'first': [2527, 2913], 'base;': [2529], 'thus,': [2530], 'long': [2535, 2616], 'untranslated': [2536], '5′-leader.': [2537], 'As': [2538], 'lacks': [2573], 'consensus': [2574, 2742], 'CCAAT': [2577], 'ubiquitous': [2588], 'nuclear': [2589], 'can': [2592, 2766], 'initiate': [2593], '(39Pugh': [2598], 'B.F.': [2599], 'Tjian': [2600, 2808], '1990;': [2603], '61:': [2604], '1187-1197Abstract': [2605], '(733)': [2611], 'GC-rich': [2617], '5′-untranslated': [2618], 'region,': [2619], 'postulated': [2630], 'translational': [2636], 'regulation': [2637, 3077, 3258], 'Scholar,23Shima': [2663], '28Bonthron': [2691], 'Orkin': [2693], 'S.H.': [2694], 'Eur': [2695], '171:': [2699], '51-57Crossref': [2700], '(22)': [2703], '40Rao': [2706], 'C.D.': [2707], 'Igarashi': [2708], 'Chiu': [2710, 2772], 'I.-M.': [2711], 'Robbins': [2712], 'Aaronson': [2714], 'S.A.': [2715], '1986;': [2720], '83:': [2721], '2392-2396Crossref': [2722], '(79)': [2725], 'addition,': [2729], 'factor.': [2749], 'cAMP-dependent': [2754], 'kinase': [2756], 'TGF-α': [2758], 'activators': [2760], 'regulate': [2767], '(41Imagawa': [2770], 'Karin': [2774], '1987;': [2777, 2811], '51:': [2778], '251-260Abstract': [2779], '(1029)': [2785], '42Gille': [2788], 'Swerlick': [2790], 'Caughman': [2792], '750-759Crossref': [2798], '(250)': [2801], '43Mitchell': [2804], 'P.J.': [2805], 'Wang': [2806], '50:': [2812], '847-861Abstract': [2813], '(627)': [2819], 'Besides,': [2822], 'approximately': [2833], '2-fold': [2834], 'induced': [2835, 2949], 'serum': [2837], 'stimulation.': [2838], 'increase': [2842, 2852], '2–5-fold': [2844], 'different': [2846], 'could': [2853], 'attributed': [2855], '(32Enholm': [2859], 'Paavonen': [2861, 3300], 'Ristimaki': [2863, 3302], 'Gunji': [2867, 3306], 'Klefstrom': [2869, 3308], 'Kivinen': [2871, 3310], 'Laiho': [2873, 3312], 'Olofsson': [2875, 3314], 'Oncogene.': [2883, 3322, 3410], '14:': [2885, 3324], '2475-2483Crossref': [2886, 3325], '(385)': [2889, 3328], 'Thus,': [2892, 3236], 'important': [2893, 2926], 'serum-responsive': [2894], 'outside': [2899], 'work,': [2908], 'example': [2910], 'intron': [2914], 'large': [2917], 'gene.Potential': [2918], 'lymphoid': [2929], 'immune': [2931], 'systems': [2932], 'found.': [2935], 'associated': [2938], 'rapid': [2940], 'response': [2941], 'activation': [2942], 'mechanisms': [2943], 'known': [2946], 'variety': [2952], 'stimuli,': [2955], 'being': [2956], 'mediator': [2958], 'tissue-specific': [2960], '(44Baeuerle': [2963], 'Baltimore': [2965, 2983], '87:': [2969], '13-20Abstract': [2970], '(2917)': [2978], '45Lenardo': [2981], 'M.J.': [2982], '58:': [2987], '227-229Abstract': [2988], '(1253)': [2994], 'presence': [2998, 3158], 'interleukin-1': [3016], 'factor-α.': [3020], '3A.': [3021], 'Ristimaki,': [3022], 'data.Unlike': [3041], 'does': [3049], 'factors.': [3057], 'Numerous': [3058], 'another': [3063], 'control': [3065], 'point': [3066], 'hypoxic': [3069], 'steady-state': [3080, 3229], 'level': [3081], '46Shweiki': [3108], 'Itin': [3110], 'Soffer': [3112], 'Nature.': [3116], '359:': [3118], '843-845Crossref': [3119], '(4124)': [3122], '47Levy': [3125], '2746-2753Abstract': [3136], '(557)': [3144], 'stability': [3150], 'determined': [3155], 'protein-binding': [3160], '3′-untranslated': [3165, 3206], '(5Klagsburn': [3167], '25Levy': [3183], 'type,': [3218], 'at': [3220], 'least': [3221], 'our': [3222], 'analyses': [3224], 'indicate': [3225], 'levels': [3230], 'increased': [3233], 'hypoxia.': [3235], 'besides': [3237], 'domains,': [3248], 'interesting': [3254], 'function': [3260], 'prototype': [3266], '32Enholm': [3298], 'Interestingly,': [3331], 'if': [3332], 'gaps': [3333], 'introduced': [3334], 'purposes': [3342], 'alignment': [3344], 'ignored': [3346], 'calculations,': [3348], 'cloned': [3351], 'FIGF/VEGF-D': [3352], 'about': [3354, 3361], '48%': [3355], 'identical': [3356, 3363], '31%': [3362], '(48Orlandini': [3367], 'Marconcini': [3369], 'Ferruzzi': [3371], 'Oliviero': [3373], '11675-11680Crossref': [3384], '(262)': [3387], '52Maglione': [3390], 'Guerriore': [3392], 'Viglietto': [3394], 'Ferraro': [3396], 'Vecchio': [3402], 'S.D.': [3403], 'Lie': [3404], 'K.-J.': [3405], 'Chou': [3406], 'J.Y.': [3407], '8:': [3412], '925-931PubMed': [3413], 'On': [3416], 'basis': [3418], 'their': [3420], 'alignments,': [3425], 'VEGF-D': [3428], 'likely': [3430], 'structural': [3434], 'properties': [3437], 'structures.': [3440], 'Perhaps': [3441], 'PDGF-A/PDGF-B': [3443], 'VEGF-C/VEGF-D': [3445], 'diverged': [3448], 'VEGF/VEGF-B': [3450], 'than': [3455], 'evolution.': [3460], 'Amino': [4058]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2140283135', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-13T02:07:43.331756', 'created_date': '2016-06-24'}