Title: Recent Advances in the Development of Small-molecule CCR5 Inhibitors for HIV
Abstract: CCR5 (C-C chemokine receptor type 5) is a chemokine receptor that has been identified as a major HIV co-receptor in viral entry and therefore is a highly validated target for the development of new anti-HIV drugs. Here, we discuss the insights gained so far relevant to the development of small-molecule CCR5 inhibitors for the treatment of HIV, and highlight small-molecule CCR5 inhibitors that are currently under preclinical and clinical trials.
Publication Year: 2010
Publication Date: 2010-11-01
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 8
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