Publication Information

{'id': 'https://openalex.org/W2138313512', 'doi': 'https://doi.org/10.1021/bi049320b', 'title': 'Effect of Salt on the Urea-Unfolded Form of Barstar Probed by <i>m</i> Value Measurements', 'display_name': 'Effect of Salt on the Urea-Unfolded Form of Barstar Probed by <i>m</i> Value Measurements', 'publication_year': 2004, 'publication_date': '2004-08-20', 'ids': {'openalex': 'https://openalex.org/W2138313512', 'doi': 'https://doi.org/10.1021/bi049320b', 'mag': '2138313512', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15350126'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi049320b', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5047773816', 'display_name': 'Lovy Pradeep', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I194223965', 'display_name': 'National Centre for Biological Sciences', 'ror': 'https://ror.org/03gf8rp76', 'country_code': 'IN', 'type': 'facility', 'lineage': ['https://openalex.org/I11947397', 'https://openalex.org/I194223965', 'https://openalex.org/I2799351866', 'https://openalex.org/I3149292468']}, {'id': 'https://openalex.org/I11947397', 'display_name': 'Tata Institute of Fundamental Research', 'ror': 'https://ror.org/03ht1xw27', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I11947397', 'https://openalex.org/I2799351866', 'https://openalex.org/I3149292468']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Lovy Pradeep', 'raw_affiliation_strings': ['National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK campus, Bangalore 560 065, India'], 'affiliations': [{'raw_affiliation_string': 'National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK campus, Bangalore 560 065, India', 'institution_ids': ['https://openalex.org/I194223965', 'https://openalex.org/I11947397']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5057549416', 'display_name': 'Jayant B. Udgaonkar', 'orcid': 'https://orcid.org/0000-0002-7005-224X'}, 'institutions': [{'id': 'https://openalex.org/I194223965', 'display_name': 'National Centre for Biological Sciences', 'ror': 'https://ror.org/03gf8rp76', 'country_code': 'IN', 'type': 'facility', 'lineage': ['https://openalex.org/I11947397', 'https://openalex.org/I194223965', 'https://openalex.org/I2799351866', 'https://openalex.org/I3149292468']}, {'id': 'https://openalex.org/I11947397', 'display_name': 'Tata Institute of Fundamental Research', 'ror': 'https://ror.org/03ht1xw27', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I11947397', 'https://openalex.org/I2799351866', 'https://openalex.org/I3149292468']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Jayant B. Udgaonkar', 'raw_affiliation_strings': ['National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK campus, Bangalore 560 065, India'], 'affiliations': [{'raw_affiliation_string': 'National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK campus, Bangalore 560 065, India', 'institution_ids': ['https://openalex.org/I194223965', 'https://openalex.org/I11947397']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.95, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.688016, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '43', 'issue': '36', 'first_page': '11393', 'last_page': '11402'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure and Dynamics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure and Dynamics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11162', 'display_name': 'Enzyme Structure and Function', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11124', 'display_name': 'Protein purification and stability', 'score': 0.9886, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/wild-type', 'display_name': 'Wild type', 'score': 0.5245086}], 'concepts': [{'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.83678794}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6955063}, {'id': 'https://openalex.org/C8010536', 'wikidata': 'https://www.wikidata.org/wiki/Q160398', 'display_name': 'Crystallography', 'level': 1, 'score': 0.642411}, {'id': 'https://openalex.org/C139447449', 'wikidata': 'https://www.wikidata.org/wiki/Q14633900', 'display_name': 'Unfolded protein response', 'level': 3, 'score': 0.6341949}, {'id': 'https://openalex.org/C2780365088', 'wikidata': 'https://www.wikidata.org/wiki/Q48318', 'display_name': 'Urea', 'level': 2, 'score': 0.5425535}, {'id': 'https://openalex.org/C207583985', 'wikidata': 'https://www.wikidata.org/wiki/Q128723', 'display_name': 'Wild type', 'level': 4, 'score': 0.5245086}, {'id': 'https://openalex.org/C204328495', 'wikidata': 'https://www.wikidata.org/wiki/Q847556', 'display_name': 'Protein folding', 'level': 2, 'score': 0.45324627}, {'id': 'https://openalex.org/C16318435', 'wikidata': 'https://www.wikidata.org/wiki/Q149299', 'display_name': 'Mutagenesis', 'level': 4, 'score': 0.4292518}, {'id': 'https://openalex.org/C47701112', 'wikidata': 'https://www.wikidata.org/wiki/Q735188', 'display_name': 'Protein structure', 'level': 2, 'score': 0.42626935}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.40557498}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.26715437}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.120616704}, {'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.09187582}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011189', 'descriptor_name': 'Potassium Chloride', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D017510', 'descriptor_name': 'Protein Folding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012492', 'descriptor_name': 'Salts', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D013816', 'descriptor_name': 'Thermodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014508', 'descriptor_name': 'Urea', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014644', 'descriptor_name': 'Genetic Variation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008956', 'descriptor_name': 'Models, Chemical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016297', 'descriptor_name': 'Mutagenesis, Site-Directed', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011189', 'descriptor_name': 'Potassium Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011489', 'descriptor_name': 'Protein Denaturation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011489', 'descriptor_name': 'Protein Denaturation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012492', 'descriptor_name': 'Salts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013050', 'descriptor_name': 'Spectrometry, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055672', 'descriptor_name': 'Static Electricity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014508', 'descriptor_name': 'Urea', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi049320b', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15350126', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Affordable and clean energy', 'score': 0.68, 'id': 'https://metadata.un.org/sdg/7'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 70, 'referenced_works': ['https://openalex.org/W111310851', 'https://openalex.org/W1486842453', 'https://openalex.org/W1525462137', 'https://openalex.org/W1526669805', 'https://openalex.org/W1588812136', 'https://openalex.org/W1592479770', 'https://openalex.org/W1593425281', 'https://openalex.org/W1594541410', 'https://openalex.org/W1605936672', 'https://openalex.org/W1911813246', 'https://openalex.org/W1965834031', 'https://openalex.org/W1967328861', 'https://openalex.org/W1970343235', 'https://openalex.org/W1974146961', 'https://openalex.org/W1978870059', 'https://openalex.org/W1986113059', 'https://openalex.org/W1987992424', 'https://openalex.org/W1989400985', 'https://openalex.org/W1990107377', 'https://openalex.org/W1992637173', 'https://openalex.org/W1992829924', 'https://openalex.org/W1996222219', 'https://openalex.org/W1996518756', 'https://openalex.org/W1998456451', 'https://openalex.org/W2000490321', 'https://openalex.org/W2000577749', 'https://openalex.org/W2004360551', 'https://openalex.org/W2006747142', 'https://openalex.org/W2007078611', 'https://openalex.org/W2009857351', 'https://openalex.org/W2015746898', 'https://openalex.org/W2017505620', 'https://openalex.org/W2027959500', 'https://openalex.org/W2034601153', 'https://openalex.org/W2040001997', 'https://openalex.org/W2045585638', 'https://openalex.org/W2051833772', 'https://openalex.org/W2057885453', 'https://openalex.org/W2059873045', 'https://openalex.org/W2060690425', 'https://openalex.org/W2063685939', 'https://openalex.org/W2066510869', 'https://openalex.org/W2067130595', 'https://openalex.org/W2071615629', 'https://openalex.org/W2073833271', 'https://openalex.org/W2076141666', 'https://openalex.org/W2086507809', 'https://openalex.org/W2086951107', 'https://openalex.org/W2089674076', 'https://openalex.org/W2094560356', 'https://openalex.org/W2095891762', 'https://openalex.org/W2097791955', 'https://openalex.org/W2107543794', 'https://openalex.org/W2108630920', 'https://openalex.org/W2114304598', 'https://openalex.org/W2117747873', 'https://openalex.org/W2118456132', 'https://openalex.org/W2118864235', 'https://openalex.org/W2119853361', 'https://openalex.org/W2120643825', 'https://openalex.org/W2122805799', 'https://openalex.org/W2123331319', 'https://openalex.org/W2129005052', 'https://openalex.org/W2129388900', 'https://openalex.org/W2137203917', 'https://openalex.org/W2148953672', 'https://openalex.org/W2171414493', 'https://openalex.org/W2321129318', 'https://openalex.org/W4285719527', 'https://openalex.org/W611537134'], 'related_works': ['https://openalex.org/W4390033782', 'https://openalex.org/W337913160', 'https://openalex.org/W3006942156', 'https://openalex.org/W2773112660', 'https://openalex.org/W2484122801', 'https://openalex.org/W2150032734', 'https://openalex.org/W2115706326', 'https://openalex.org/W2090107439', 'https://openalex.org/W2083382121', 'https://openalex.org/W1965514223'], 'abstract_inverted_index': {'To': [0, 185], 'probe': [1], 'for': [2, 105, 133], 'residual': [3, 179, 263], 'structure': [4, 28, 180, 264, 298], 'present': [5, 192, 220], 'in': [6, 88, 163, 181, 193, 221, 251, 265, 279], 'the': [7, 11, 31, 34, 46, 65, 68, 76, 85, 93, 107, 129, 134, 143, 154, 169, 182, 188, 194, 198, 201, 205, 208, 211, 218, 222, 233, 237, 247, 252, 260, 266, 280, 292, 297, 303, 310, 313], 'urea-unfolded': [8], 'form': [9, 87, 156, 196, 224, 268], 'of': [10, 33, 45, 67, 80, 82, 142, 178, 190, 200, 207, 236, 254, 286, 294, 302, 312], 'small': [12], 'protein': [13, 48, 136, 282, 305], 'barstar,': [14], 'to': [15, 24, 90, 125, 246, 306, 309], 'determine': [16, 25], 'how': [17, 26], 'salt': [18, 202, 261, 295], 'might': [19, 29], 'modulate': [20], 'such': [21, 27], 'structure,': [22], 'and': [23, 146, 210, 240, 276, 299], 'affect': [30], 'stability': [32, 311], 'protein,': [35], 'mutant': [36, 53, 115, 121, 127, 148, 212, 242], 'variants': [37], 'that': [38, 44, 91, 232, 259, 273], 'display': [39], 'm': [40, 72, 108, 130, 170, 234, 249], 'values': [41, 109, 235], 'different': [42, 151], 'from': [43, 98, 160], 'wild-type': [47, 135, 209, 248], 'have': [49], 'been': [50, 173], 'studied.': [51, 138, 228], 'The': [52, 71, 139, 284], 'proteins': [54, 104, 149, 243], 'were': [55, 110, 137, 226], 'obtained': [56], 'by': [57, 269], 'site-directed': [58], 'mutagenesis': [59], 'at': [60], 'residue': [61], 'positions': [62], 'located': [63], 'on': [64, 204, 217, 296], 'surface': [66, 166], 'folded': [69, 94], 'protein.': [70, 314], 'value,': [73], 'which': [74, 106, 158], 'represents': [75], 'preferential': [77], 'free': [78, 287, 300], 'energy': [79, 288, 301], 'interaction': [81], 'urea': [83], 'with': [84, 92], 'unfolded': [86, 140, 155, 183, 195, 223, 267, 281, 304], 'comparison': [89], 'state,': [95], 'was': [96, 230], 'determined': [97, 132], 'equilibrium': [99], 'urea-induced': [100], 'unfolding': [101], 'curves.': [102], 'Mutant': [103], 'significantly': [111, 117], 'greater': [112], 'than': [113, 119], '(m+': [114], 'forms),': [116, 122], 'smaller': [118], '(m-': [120], 'or': [123], 'similar': [124], '(m0': [126], 'forms)': [128], 'value': [131, 171, 250], 'forms': [141], 'm0,': [144, 238], 'm+': [145, 239], 'm-': [147, 241], 'represent': [150], 'components': [152, 278], 'within': [153], 'ensemble,': [157, 197, 225], 'differ': [159], 'each': [161], 'other': [162], 'their': [164], 'solvent-exposed': [165], 'areas.': [167], 'Hence,': [168], 'has': [172, 290], 'used': [174], 'as': [175, 214, 216], 'a': [176], 'measure': [177], 'form.': [184], 'further': [186], 'understand': [187], 'nature': [189], 'structures': [191, 219], 'effects': [199], 'KCl': [203], 'stabilities': [206], 'proteins,': [213], 'well': [215], 'also': [227], 'It': [229], 'found': [231], 'all': [244], 'converge': [245], 'presence': [253], 'KCl.': [255], 'This': [256], 'result': [257], 'indicates': [258], 'modulates': [262], 'screening': [270], 'electrostatic': [271], 'interactions': [272], 'maintain': [274], 'compact': [275], 'expanded': [277], 'ensemble.': [283], 'use': [285], 'cycles': [289], 'allowed': [291], 'effect': [293], 'be': [307], 'related': [308]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2138313512', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-08T05:06:22.730288', 'created_date': '2016-06-24'}