Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2137886140', 'doi': 'https://doi.org/10.3109/00016487209128443', 'title': 'Cytoplasmic Processes in Normal and in Malignant Oral Epithelium', 'display_name': 'Cytoplasmic Processes in Normal and in Malignant Oral Epithelium', 'publication_year': 1972, 'publication_date': '1972-01-01', 'ids': {'openalex': 'https://openalex.org/W2137886140', 'doi': 'https://doi.org/10.3109/00016487209128443', 'mag': '2137886140', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/5080254'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/00016487209128443', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S198335345', 'display_name': 'Acta Oto-Laryngologica', 'issn_l': '0001-6489', 'issn': ['0001-6489', '1651-2251'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081577252', 'display_name': 'Lars Frithiof', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': True, 'raw_author_name': 'L. Frithiof', 'raw_affiliation_strings': ['Department of Oral Surgery, Faculty of Dentistry, Karolinska Institutet, Stockholm, Sweden', 'King Gustaf V Research Institute and the Department of Otolaryngology, Karolinska Sjukhuset, Stockholm, Sweden'], 'affiliations': [{'raw_affiliation_string': 'King Gustaf V Research Institute and the Department of Otolaryngology, Karolinska Sjukhuset, Stockholm, Sweden', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Oral Surgery, Faculty of Dentistry, Karolinska Institutet, Stockholm, Sweden', 'institution_ids': ['https://openalex.org/I28166907']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5081577252'], 'corresponding_institution_ids': ['https://openalex.org/I28166907'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.769, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.775922, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '74', 'issue': '1-6', 'first_page': '212', 'last_page': '229'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12793', 'display_name': 'Caveolin-1 and cellular processes', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12793', 'display_name': 'Caveolin-1 and cellular processes', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11131', 'display_name': 'Proteoglycans and glycosaminoglycans research', 'score': 0.9917, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11452', 'display_name': 'Oral Health Pathology and Treatment', 'score': 0.987, 'subfield': {'id': 'https://openalex.org/subfields/3506', 'display_name': 'Periodontics'}, 'field': {'id': 'https://openalex.org/fields/35', 'display_name': 'Dentistry'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cell-type', 'display_name': 'Cell type', 'score': 0.42566726}], 'concepts': [{'id': 'https://openalex.org/C2776193487', 'wikidata': 'https://www.wikidata.org/wiki/Q32846', 'display_name': 'Basement membrane', 'level': 2, 'score': 0.87086034}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.84020555}, {'id': 'https://openalex.org/C529295009', 'wikidata': 'https://www.wikidata.org/wiki/Q41301', 'display_name': 'Epithelium', 'level': 2, 'score': 0.80646634}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.6275808}, {'id': 'https://openalex.org/C518705261', 'wikidata': 'https://www.wikidata.org/wiki/Q25615', 'display_name': 'Connective tissue', 'level': 2, 'score': 0.6253581}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.56792235}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.43383786}, {'id': 'https://openalex.org/C189014844', 'wikidata': 'https://www.wikidata.org/wiki/Q189118', 'display_name': 'Cell type', 'level': 3, 'score': 0.42566726}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.36697912}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.31426448}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.14727384}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002278', 'descriptor_name': 'Carcinoma in Situ', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004428', 'descriptor_name': 'Ear Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001485', 'descriptor_name': 'Basement Membrane', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001485', 'descriptor_name': 'Basement Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002278', 'descriptor_name': 'Carcinoma in Situ', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003238', 'descriptor_name': 'Connective Tissue', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003238', 'descriptor_name': 'Connective Tissue', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003896', 'descriptor_name': 'Desmosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004423', 'descriptor_name': 'Ear', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D004423', 'descriptor_name': 'Ear', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D004423', 'descriptor_name': 'Ear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004428', 'descriptor_name': 'Ear Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/00016487209128443', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S198335345', 'display_name': 'Acta Oto-Laryngologica', 'issn_l': '0001-6489', 'issn': ['0001-6489', '1651-2251'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/5080254', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/15', 'score': 0.4, 'display_name': 'Life on land'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W14401474', 'https://openalex.org/W1465281865', 'https://openalex.org/W1474899338', 'https://openalex.org/W1517431460', 'https://openalex.org/W1573011249', 'https://openalex.org/W1573866362', 'https://openalex.org/W1582796640', 'https://openalex.org/W1619294685', 'https://openalex.org/W1749233240', 'https://openalex.org/W1947825090', 'https://openalex.org/W1965206206', 'https://openalex.org/W1981251933', 'https://openalex.org/W1997182014', 'https://openalex.org/W1999527192', 'https://openalex.org/W2001655987', 'https://openalex.org/W2002673623', 'https://openalex.org/W2007677089', 'https://openalex.org/W2009431843', 'https://openalex.org/W2012544113', 'https://openalex.org/W2015525665', 'https://openalex.org/W2027325645', 'https://openalex.org/W2027417773', 'https://openalex.org/W2028133309', 'https://openalex.org/W2030326481', 'https://openalex.org/W2032872652', 'https://openalex.org/W2044350649', 'https://openalex.org/W2055214702', 'https://openalex.org/W2067563956', 'https://openalex.org/W2069145546', 'https://openalex.org/W2072684357', 'https://openalex.org/W2075579443', 'https://openalex.org/W2079345637', 'https://openalex.org/W2093884083', 'https://openalex.org/W2094437917', 'https://openalex.org/W2097997775', 'https://openalex.org/W2102632795', 'https://openalex.org/W2106462555', 'https://openalex.org/W2125170171', 'https://openalex.org/W2129125401', 'https://openalex.org/W2149239195', 'https://openalex.org/W2161898659', 'https://openalex.org/W2212207049', 'https://openalex.org/W2291019245', 'https://openalex.org/W2342694851', 'https://openalex.org/W2409009789', 'https://openalex.org/W2410873400', 'https://openalex.org/W2417255179', 'https://openalex.org/W2417287018', 'https://openalex.org/W2430203822', 'https://openalex.org/W2434105298', 'https://openalex.org/W252728737', 'https://openalex.org/W2972603276', 'https://openalex.org/W36495337'], 'related_works': ['https://openalex.org/W4245677458', 'https://openalex.org/W2465986824', 'https://openalex.org/W2317944091', 'https://openalex.org/W2171117751', 'https://openalex.org/W2067652211', 'https://openalex.org/W2012917028', 'https://openalex.org/W2011405657', 'https://openalex.org/W1994795620', 'https://openalex.org/W1991124285', 'https://openalex.org/W1966475075'], 'abstract_inverted_index': {'The': [0, 55, 156], 'cytoplasmic': [1, 28, 59, 86, 100, 160], 'processes': [2, 29, 60, 87, 101], 'in': [3, 31, 80, 90, 103, 118, 176], 'preinvasive': [4, 71], 'and': [5, 15, 38, 45, 51, 72, 96, 112, 126, 140, 189, 215, 223], 'invasive': [6, 73, 207], 'carcinoma': [7, 135], 'of': [8, 21, 27, 35, 57, 67, 85, 99, 129, 152, 158, 220, 230], 'the': [9, 18, 22, 32, 47, 58, 63, 68, 104, 109, 113, 119, 127, 141, 169, 177, 180, 198, 206, 227, 231], 'human': [10], 'oral': [11], 'epithelium': [12], 'were': [13], 'examined': [14], 'compared': [16], 'with': [17, 53], 'corresponding': [19], 'structures': [20], 'normal': [23, 37, 69, 120, 181], 'epithelium.': [24, 40], 'Two': [25], 'types': [26, 84, 98], 'occur': [30], 'intercellular': [33, 105], 'space': [34], 'both': [36, 83], 'pathologic': [39], 'One': [41], 'type': [42], 'is': [43, 77, 116, 138, 187, 201], 'long': [44], 'slender,': [46], 'other': [48], 'wide-based,': [49], 'tonofilament-containing': [50], 'associated': [52], 'desmosomes.': [54], 'distribution': [56], 'varies': [61], 'between': [62, 108], 'different': [64], 'cellular': [65], 'strata': [66], 'epithelium.In': [70], 'carcinoma,': [74], 'where': [75], 'there': [76], 'great': [78], 'variation': [79], 'stratification': [81], 'regularity,': [82, 125], 'vary': [88], 'widely': [89], 'number': [91], 'from': [92], 'cell': [93, 111], 'to': [94, 168], 'cell,': [95], 'additional': [97], 'appear': [102], 'space.The': [106], 'border': [107, 137], 'basal': [110], 'connective': [114], 'tissue': [115], 'characterized,': [117], 'tissue,': [121], 'by': [122, 184, 191], 'a': [123, 130, 164], 'certain': [124], 'presence': [128, 157], 'continuous': [131], 'basement': [132, 142, 165], 'membrane.': [133], 'In': [134], 'this': [136], 'irregular,': [139], 'membrane': [143], 'may': [144, 218], 'be': [145, 219], 'absent,': [146], 'extremely': [147], 'thin,': [148], 'multilayered': [149], 'or': [150], 'composed': [151], 'an': [153, 202], 'atypical': [154], 'material.': [155], 'various': [159], 'processes,': [161], 'all': [162], 'without': [163], 'membrane,': [166], 'contributes': [167], 'irregular': [170], 'pattern.': [171], 'There': [172], 'are': [173], 'also': [174], 'changes': [175, 217], 'subepithelial': [178], 'tissue:': [179], 'pattern,': [182], 'dominated': [183], 'collagen': [185], 'fibrils,': [186], 'destroyed': [188], 'replaced': [190], 'electron-lucent': [192], 'areas.': [193], 'It': [194, 209], 'was': [195, 210], 'suggested': [196], 'that': [197, 212], 'destructive': [199], 'activity': [200, 229], 'early': [203], 'feature': [204], 'preceding': [205], 'process.': [208], 'concluded': [211], 'these': [213], 'prevailing': [214], 'well-defined': [216], 'diagnostic': [221], 'importance': [222], 'provide': [224], 'information': [225], 'on': [226], 'migratory': [228], 'malignant': [232], 'cell.': [233]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2137886140', 'counts_by_year': [], 'updated_date': '2024-12-10T18:02:50.724501', 'created_date': '2016-06-24'}