Publication Information

{'id': 'https://openalex.org/W2137463654', 'doi': 'https://doi.org/10.1093/nar/gkl300', 'title': 'Kinetics of error generation in homologous B-family DNA polymerases', 'display_name': 'Kinetics of error generation in homologous B-family DNA polymerases', 'publication_year': 2006, 'publication_date': '2006-05-10', 'ids': {'openalex': 'https://openalex.org/W2137463654', 'doi': 'https://doi.org/10.1093/nar/gkl300', 'mag': '2137463654', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16687658', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1459414'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkl300', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/34/9/2528/7129448/gkl300.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://academic.oup.com/nar/article-pdf/34/9/2528/7129448/gkl300.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044457209', 'display_name': 'Matthew Hogg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Hogg', 'raw_affiliation_strings': ['Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, 05405, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, 05405, USA.', 'institution_ids': ['https://openalex.org/I111236770']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081704621', 'display_name': 'W. Grant Cooper', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'W. Cooper', 'raw_affiliation_strings': ['Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont 05405 and'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont 05405 and', 'institution_ids': ['https://openalex.org/I111236770']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031007485', 'display_name': 'Linda J. Reha-Krantz', 'orcid': 'https://orcid.org/0000-0003-4497-423X'}, 'institutions': [{'id': 'https://openalex.org/I154425047', 'display_name': 'University of Alberta', 'ror': 'https://ror.org/0160cpw27', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I154425047']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'L. Reha-Krantz', 'raw_affiliation_strings': ['Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada', 'institution_ids': ['https://openalex.org/I154425047']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051791551', 'display_name': 'Susan S. Wallace', 'orcid': 'https://orcid.org/0000-0002-3906-0321'}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S. S. Wallace', 'raw_affiliation_strings': ['Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont 05405 and'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont 05405 and', 'institution_ids': ['https://openalex.org/I111236770']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3630, 'currency': 'USD', 'value_usd': 3630, 'provenance': 'doaj'}, 'apc_paid': {'value': 3630, 'currency': 'USD', 'value_usd': 3630, 'provenance': 'doaj'}, 'fwci': 1.074, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 23, 'citation_normalized_percentile': {'value': 0.769205, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '34', 'issue': '9', 'first_page': '2528', 'last_page': '2535'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10432', 'display_name': 'DNA and Nucleic Acid Chemistry', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9884, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777501222', 'wikidata': 'https://www.wikidata.org/wiki/Q411664', 'display_name': 'Exonuclease', 'level': 4, 'score': 0.8543515}, {'id': 'https://openalex.org/C2756471', 'wikidata': 'https://www.wikidata.org/wiki/Q206286', 'display_name': 'DNA polymerase', 'level': 3, 'score': 0.80496}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.72225505}, {'id': 'https://openalex.org/C82381507', 'wikidata': 'https://www.wikidata.org/wiki/Q416878', 'display_name': 'Polymerase', 'level': 3, 'score': 0.6082746}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.5704905}, {'id': 'https://openalex.org/C185581394', 'wikidata': 'https://www.wikidata.org/wiki/Q145911', 'display_name': 'Base pair', 'level': 3, 'score': 0.48019087}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.45499027}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.40698212}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.37883157}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.37285548}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.10631549}], 'mesh': [{'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D004259', 'descriptor_name': 'DNA-Directed DNA Polymerase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020137', 'descriptor_name': 'Base Pair Mismatch', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020029', 'descriptor_name': 'Base Pairing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D004259', 'descriptor_name': 'DNA-Directed DNA Polymerase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004259', 'descriptor_name': 'DNA-Directed DNA Polymerase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004259', 'descriptor_name': 'DNA-Directed DNA Polymerase', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D003838', 'descriptor_name': 'Deoxyadenine Nucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003838', 'descriptor_name': 'Deoxyadenine Nucleotides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D005663', 'descriptor_name': 'Furans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005663', 'descriptor_name': 'Furans', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013941', 'descriptor_name': 'Thymine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013941', 'descriptor_name': 'Thymine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014764', 'descriptor_name': 'Viral Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkl300', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/34/9/2528/7129448/gkl300.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1459414', 'pdf_url': 'https://europepmc.org/articles/pmc1459414?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459414', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16687658', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkl300', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/34/9/2528/7129448/gkl300.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 37, 'referenced_works': ['https://openalex.org/W1493170168', 'https://openalex.org/W1497215682', 'https://openalex.org/W1497895255', 'https://openalex.org/W1518934584', 'https://openalex.org/W1530517085', 'https://openalex.org/W1541696918', 'https://openalex.org/W1597138031', 'https://openalex.org/W1602417853', 'https://openalex.org/W1902420624', 'https://openalex.org/W1983358133', 'https://openalex.org/W1993452701', 'https://openalex.org/W1994546938', 'https://openalex.org/W1997862281', 'https://openalex.org/W1998657111', 'https://openalex.org/W2002578927', 'https://openalex.org/W2008554680', 'https://openalex.org/W2009442572', 'https://openalex.org/W2017626786', 'https://openalex.org/W2017950533', 'https://openalex.org/W2019981881', 'https://openalex.org/W2034035353', 'https://openalex.org/W2035834598', 'https://openalex.org/W2040512695', 'https://openalex.org/W2043070639', 'https://openalex.org/W2057979557', 'https://openalex.org/W2060553286', 'https://openalex.org/W2065999793', 'https://openalex.org/W2068130878', 'https://openalex.org/W2076058601', 'https://openalex.org/W2079527280', 'https://openalex.org/W2093177397', 'https://openalex.org/W2107119563', 'https://openalex.org/W2107520545', 'https://openalex.org/W2131566401', 'https://openalex.org/W2134259738', 'https://openalex.org/W255996521', 'https://openalex.org/W47123523'], 'related_works': ['https://openalex.org/W4285393835', 'https://openalex.org/W2398277866', 'https://openalex.org/W2137463654', 'https://openalex.org/W2077167296', 'https://openalex.org/W2076445634', 'https://openalex.org/W2074011169', 'https://openalex.org/W2031882707', 'https://openalex.org/W2014466457', 'https://openalex.org/W1936051282', 'https://openalex.org/W1510369003'], 'abstract_inverted_index': {'The': [0, 85, 121, 156], 'kinetics': [1], 'of': [2, 35, 70, 100, 116, 210], 'forming': [3], 'a': [4, 141], 'proper': [5], 'Watson–Crick': [6], 'base': [7], 'pair': [8], 'as': [9, 78, 80, 110, 112], 'well': [10, 21, 79, 111], 'incorporating': [11], 'bases': [12], 'opposite': [13, 103, 108, 169], 'furan,': [14, 170], 'an': [15, 101, 106], 'abasic': [16], 'site': [17], 'analog,': [18], 'have': [19, 39], 'been': [20, 41], 'characterized': [22], 'for': [23, 88, 93, 98, 113, 158, 201], 'the': [24, 44, 53, 67, 71, 114, 133, 147, 175, 188, 207, 211], 'B': [25], 'Family': [26], 'replicative': [27], 'DNA': [28, 203, 213], 'polymerase': [29, 204], 'from': [30, 47, 56], 'bacteriophage': [31, 48], 'T4.': [32], 'Structural': [33], 'studies': [34], 'these': [36], 'reactions,': [37], 'however,': [38], 'only': [40], 'performed': [42], 'with': [43, 167], 'homologous': [45, 54], 'enzyme': [46, 95], 'RB69.': [49], 'In': [50], 'this': [51], 'work,': [52], 'enzymes': [55, 190], 'RB69': [57, 135, 177, 212], 'and': [58, 105, 118, 150], 'T4': [59, 122, 162, 202], 'were': [60, 96, 125, 163], 'compared': [61, 166], 'in': [62, 146], 'parallel': [63], 'reactions': [64], 'to': [65, 74, 81, 128, 197], 'determine': [66], 'relative': [68], 'abilities': [69], 'two': [72, 189], 'polymerases': [73], 'incorporate': [75], 'correct': [76], 'nucleotides': [77], 'form': [82], 'improper': [83], 'pairings.': [84], 'kinetic': [86, 185], 'rates': [87, 157], 'three': [89], 'different': [90], 'exonuclease': [91, 123, 136, 152], 'mutants': [92, 124, 137], 'each': [94], 'measured': [97], 'incorporation': [99, 168], 'A': [102, 107], 'T': [104, 142], 'furan': [109, 144], 'formation': [115, 160], 'A:C': [117], 'T:T': [119], 'mismatches.': [120], 'all': [126], '∼2-': [127], '7-fold': [129], 'more': [130, 172], 'efficient': [131], 'than': [132, 174], 'corresponding': [134, 176], 'depending': [138], 'on': [139, 206], 'whether': [140], 'or': [143], 'was': [145, 154], 'templating': [148], 'position': [149], 'which': [151], 'mutant': [153], 'used.': [155], 'mismatch': [159], 'by': [161], 'significantly': [164], 'reduced': [165], 'much': [171], 'so': [173], 'mutant.': [178], 'These': [179], 'results': [180], 'show': [181], 'that': [182], 'there': [183], 'are': [184, 193], 'differences': [186], 'between': [187], 'but': [191], 'they': [192], 'not': [194], 'large': [195], 'enough': [196], 'preclude': [198], 'structural': [199], 'assumptions': [200], 'based': [205], 'known': [208], 'structure': [209], 'polymerase.': [214]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2137463654', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-05T09:46:32.818202', 'created_date': '2016-06-24'}