Title: Effects of substitution of dietary fish oil with a blend of vegetable oils on liver and peripheral blood leucocyte fatty acid composition, plasma prostaglandin E<sub>2</sub>and immune parameters in three strains of Atlantic salmon (<i>Salmo salar</i>)
Abstract: Aquaculture NutritionVolume 15, Issue 6 p. 596-607 Effects of substitution of dietary fish oil with a blend of vegetable oils on liver and peripheral blood leucocyte fatty acid composition, plasma prostaglandin E2 and immune parameters in three strains of Atlantic salmon (Salmo salar) I.K. PETROPOULOS, I.K. PETROPOULOS Present address: Nireus S.A.Xiliadou 33056, Fokida, Greece Search for more papers by this authorK.D. THOMPSON, K.D. THOMPSON Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorA. MORGAN, A. MORGAN Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorJ.R. DICK, J.R. DICK Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorD.R. TOCHER, D.R. TOCHER Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorJ. G BELL, J. G BELL Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this author I.K. PETROPOULOS, I.K. PETROPOULOS Present address: Nireus S.A.Xiliadou 33056, Fokida, Greece Search for more papers by this authorK.D. THOMPSON, K.D. THOMPSON Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorA. MORGAN, A. MORGAN Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorJ.R. DICK, J.R. DICK Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorD.R. TOCHER, D.R. TOCHER Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this authorJ. G BELL, J. G BELL Institute of Aquaculture, University of Stirling, Stirling, Scotland, UKSearch for more papers by this author First published: 04 November 2009 https://doi.org/10.1111/j.1365-2095.2008.00627.xCitations: 36 Dr J.G. Bell, Nutrition Group, Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, Scotland, UK. E-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Duplicate groups of three genetic strains of Atlantic salmon smolts were cultured on diets containing either fish oil (FO) or a blend of vegetable oils (VO). Fatty acid compositions of liver and peripheral blood leucocytes were compared. The effect of different strains and diets on innate immune parameters and plasma prostaglandin E2 were also measured. Two strains were selected as being either ‘fat’ or ‘lean’ in terms of muscle adiposity. The third strain was a commercial stock (MH). Total replacement of dietary FO with VO resulted in reduced docosahexaenoic (DHA; 22:6n-3) and eicosapentaenoic acids (EPA; 20:5n-3) in liver, while oleic (18:1n-9), linoleic (18:2n-6) and α-linolenic (18:3n-3) acids were all increased in VO-fed fish. Fatty acid compositions of blood leucocytes showed similar changes. Evaluation of innate immune function showed that in the fat strain, circulating leucocytes were significantly lower in VO fish. The lean strain also had significantly higher serum lysozyme activity than MH fish. Reduced haematocrit was seen in VO lean fish compared with FO lean fish. 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