Publication Information

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'abstract_inverted_index': {'Stem': [0, 196], 'cell': [1, 25, 197, 221, 394, 403, 455, 489, 541, 1690, 1730, 1816, 1880, 3866, 3875, 3927, 3961, 4013], 'factor': [2, 198, 395, 470, 482, 556, 568, 707, 812, 1326, 1534, 3867, 3942, 3954, 4028, 4040, 4179, 4284], '(SCF)': [3, 199, 396, 3868], 'and': [4, 17, 23, 53, 60, 69, 89, 161, 200, 213, 219, 249, 256, 265, 285, 357, 411, 441, 497, 527, 690, 708, 789, 815, 827, 928, 941, 1091, 1131, 1227, 1246, 1331, 1387, 1556, 1567, 1571, 1624, 1711, 1726, 1818, 1845, 1854, 1871, 1903, 1911, 1960, 1968, 1987, 2002, 2028, 2151, 2245, 2261, 2296, 2314, 2457, 2460, 2589, 2622, 2690, 2781, 2829, 2911, 2982, 3346, 3408, 3457, 3502, 3543, 3559, 3590, 3728, 3762, 3784, 3787, 3801, 3823, 3883, 3913, 3969, 3999, 4162, 4180, 4261, 4287, 4299], 'its': [5, 201, 772, 922, 3242, 4244], 'tyrosine': [6, 54, 126, 202, 250, 322, 785, 1082, 1141, 1195, 1329, 1447, 1715, 1840, 1961, 2026, 2051, 2119, 2243, 2448, 2617, 2687, 2765, 2947, 2976, 3051, 3131, 3243, 3304, 3314, 4257], 'kinase': [7, 127, 142, 203, 323, 338, 427, 513, 786, 1448, 2015, 2120, 2527, 2590, 2695, 2948, 3899, 3985, 4258], 'receptor,': [8, 204, 820, 2760, 2933, 3737, 4292], 'c-Kit,': [9, 205, 2188], 'play': [10, 206, 1092, 1661, 2801], 'a': [11, 29, 137, 141, 207, 225, 333, 337, 422, 431, 508, 517, 573, 692, 1093, 1194, 1211, 1320, 1531, 1597, 1627, 1662, 1679, 1712, 1756, 1858, 1892, 1924, 2011, 2137, 2140, 2248, 2627, 2802, 2930, 3048, 3233, 3293, 3535, 3894, 3903, 3980, 3989, 4045, 4164], 'crucial': [12, 208, 3758], 'role': [13, 209, 1663, 1758, 1893, 1925, 2123, 2804, 3837], 'in': [14, 98, 147, 189, 210, 294, 343, 385, 572, 790, 1444, 1535, 1604, 1626, 1761, 1807, 1812, 1819, 1847, 1855, 1876, 1886, 1894, 1930, 1991, 1997, 2003, 2118, 2127, 2154, 2192, 2194, 2455, 2458, 2465, 2585, 2693, 2805, 2825, 2869, 2945, 3023, 3050, 3057, 3087, 3133, 3312, 3357, 3362, 3412, 3488, 3732, 3740, 3782, 3857, 4044, 4262], 'regulating': [15, 211, 1762], 'migration': [16, 212], 'proliferation': [18, 214, 713, 1691, 1731, 4185], 'of': [19, 31, 41, 56, 62, 81, 101, 121, 129, 185, 191, 215, 227, 237, 252, 258, 277, 297, 317, 325, 381, 387, 413, 435, 445, 499, 521, 531, 575, 714, 771, 775, 795, 805, 823, 832, 931, 1098, 1121, 1126, 1133, 1231, 1322, 1411, 1629, 1631, 1668, 1683, 1714, 1717, 1759, 1765, 1803, 1842, 1896, 1918, 1921, 1932, 1942, 1953, 1963, 1973, 2045, 2124, 2144, 2187, 2241, 2253, 2368, 2376, 2541, 2576, 2636, 2698, 2754, 2758, 2764, 2772, 2776, 2786, 2789, 2796, 2821, 2865, 2956, 2971, 3019, 3027, 3130, 3137, 3321, 3327, 3344, 3374, 3378, 3415, 3451, 3547, 3567, 3656, 3667, 3672, 3710, 3750, 3752, 3770, 3778, 3792, 3799, 3805, 3835, 3885, 3907, 3917, 3971, 3993, 4003, 4047, 4186, 4243, 4247, 4267, 4277, 4295, 4304], 'melanoblasts,': [20, 216], 'germ': [21, 217], 'cells,': [22, 218, 774, 3742, 4246], 'hemopoietic': [24, 220, 700, 716, 4172, 4188], 'progenitors': [26, 222, 717, 4189], 'by': [27, 223, 765, 1369, 2578, 3701, 3725, 3839, 4237], 'activating': [28, 224], 'number': [30, 226, 574, 1628, 4046], 'intracellular': [32, 183, 228, 379, 2822, 2877, 3351], 'signaling': [33, 229, 1095, 1449, 2129, 2807, 3849], 'molecules.': [34, 230], 'Here': [35, 231], 'we': [36, 232, 1799, 1949, 3286, 3647, 3808], 'report': [37, 233], 'that': [38, 153, 181, 234, 349, 377, 696, 1084, 1138, 1327, 1601, 1658, 1678, 1834, 2019, 2183, 2234, 2271, 2315, 2525, 2574, 2626, 2752, 2906, 2929, 3047, 3116, 3292, 3341, 3398, 3487, 3553, 3649, 3677, 3689, 3720, 3747, 3775, 3788, 3810, 4168], 'SCF': [39, 78, 235, 274, 761, 780, 919, 1771, 1810, 1835, 1954, 1994, 2226, 2908, 3180, 3650, 3812, 4233, 4252], 'stimulation': [40, 236, 1145, 1811, 1995, 2021, 2041, 2158, 3181, 3651, 3813], 'myeloid': [42, 238, 1879, 1999], 'cells': [43, 239, 1769, 1821, 1848, 1856, 2001, 3733], 'or': [44, 113, 240, 309, 1205, 1415, 1503, 1827, 2222, 2378, 2630, 3619, 3660, 3821], 'fibroblasts': [45, 241, 439, 525, 2870, 3911, 3997], 'ectopically': [46, 242], 'expressing': [47, 243, 1822, 1849, 1857, 2871, 3734], 'c-Kit': [48, 186, 244, 382, 423, 448, 509, 534, 1830, 1922, 1974, 2699, 2777, 3148, 3352, 3779, 3793, 3895, 3920, 3981, 4006], 'induces': [49, 245, 1202, 2042], 'physical': [50, 246, 1957, 2029], 'association': [51, 247, 1958, 2030], 'with': [52, 248, 699, 802, 1417, 1672, 1891, 1959, 2010, 2031, 2136, 2265, 2276, 2453, 2536, 2780, 2919, 2924, 3359, 3569, 3663, 3819, 4171, 4274], 'phosphorylation': [55, 251, 1142, 1330, 1841, 1962, 2027, 2052, 2583, 2977, 3315], 'three': [57, 253, 3077], 'signal': [58, 254, 409, 495, 2217, 3060, 3332, 3881, 3967], 'transducers': [59, 255, 410, 496, 1130, 3882, 3968], 'activators': [61, 257, 412, 498, 1132, 3884, 3970], 'transcription': [63, 259, 1533, 3120], '(STATs)': [64, 260], 'as': [65, 111, 261, 307, 704, 809, 935, 1319, 1413, 1422, 1452, 1530, 1569, 3172, 3232, 3512, 3617, 4176, 4281], 'follows:': [66, 262, 3173], 'STAT1α,': [67, 96, 263, 292, 1843, 1901, 1985], 'STAT5A,': [68, 264, 1244, 1844, 1902, 1986], 'STAT5B.': [70, 266], 'Other': [71, 267], 'STAT': [72, 134, 148, 194, 268, 330, 344, 390, 1127, 1238, 1419, 1442, 1804, 1865, 1964, 1982, 2025, 2050, 2128, 2219, 2235, 2620, 2783, 2797, 2806, 2957, 3313, 3452, 3571], 'proteins': [73, 269, 933, 1128, 1137, 1239, 1564, 2047, 2126, 2236, 2798, 3237, 3339, 3572, 3727], 'are': [74, 187, 270, 383, 763, 1079, 1085, 1874, 2268, 3081, 3605, 3780, 4235], 'not': [75, 271, 2131, 2229, 2372, 2520, 2685, 2923, 3283, 3336, 3366, 3688, 3739, 3804], 'recruited': [76, 272], 'upon': [77, 273, 1088, 1328, 2225, 3179, 3811], 'stimulation.': [79, 275], 'Recruitment': [80, 276], 'STATs': [82, 278, 3400, 3842], 'leads': [83, 279, 924, 3652], 'to': [84, 91, 104, 117, 167, 280, 287, 300, 313, 363, 711, 783, 792, 921, 925, 1198, 1223, 1334, 1404, 1406, 1687, 1770, 1809, 1838, 1888, 1908, 1913, 1926, 1939, 1955, 1993, 2023, 2049, 2148, 2156, 2218, 2223, 2260, 2380, 2533, 2778, 2792, 2800, 2935, 3089, 3151, 3159, 3238, 3277, 3331, 3333, 3337, 3460, 3494, 3564, 3588, 3597, 3612, 3653, 3681, 3691, 3829, 3852, 3859, 4183, 4255, 4264], 'their': [85, 175, 281, 371, 1203, 3405], 'dimerization,': [86, 282, 926], 'nuclear': [87, 162, 283, 358], 'translocation,': [88, 284], 'binding': [90, 286, 920, 930, 1090, 1216, 2635, 2785, 3465, 3545, 3611, 3670], 'specific': [92, 288, 1224, 1598, 1914, 3536], 'promoter-responsive': [93, 289], 'elements.': [94, 290, 1916], 'Whereas': [95, 291], 'possibly': [97, 293], 'the': [99, 118, 122, 155, 192, 295, 314, 318, 351, 388, 426, 446, 512, 532, 766, 769, 776, 784, 793, 806, 816, 821, 1124, 1199, 1220, 1229, 1335, 1407, 1445, 1536, 1605, 1666, 1676, 1718, 1763, 1796, 1801, 1823, 1850, 1877, 1899, 1906, 1927, 1946, 1951, 2007, 2014, 2032, 2036, 2122, 2184, 2232, 2254, 2269, 2366, 2374, 2446, 2523, 2526, 2537, 2613, 2637, 2694, 2755, 2759, 2770, 2773, 2790, 2793, 2835, 2920, 2925, 2946, 3017, 3024, 3028, 3128, 3134, 3138, 3144, 3157, 3239, 3290, 3322, 3325, 3328, 3342, 3360, 3370, 3375, 3413, 3416, 3454, 3461, 3489, 3496, 3509, 3565, 3598, 3608, 3613, 3654, 3668, 3678, 3682, 3692, 3707, 3718, 3721, 3735, 3744, 3748, 3753, 3771, 3789, 3824, 3830, 3836, 3848, 3860, 3898, 3918, 3984, 4004, 4238, 4241, 4248, 4256, 4265, 4278, 4288, 4293], 'form': [100, 296, 2143, 3817], 'homodimers,': [102, 298], 'binds': [103, 299, 1333, 3828], 'thesis-inducible': [105, 301], 'DNA': [106, 302, 1215, 1915, 3464, 3544, 3669], 'element,': [107, 303], 'STAT5': [108, 170, 304, 366, 1526, 1563, 1659, 1684, 1724, 1760, 1933, 2577, 2638, 2827, 2866, 2912, 3013, 3059, 3085, 3236, 3338, 3347, 3364, 3498, 3548, 3554, 3603, 3726], 'proteins,': [109, 171, 305, 367, 1866, 1934, 1983, 2913, 3499, 3555], 'either': [110, 306], 'STAT5A/STAT5B': [112, 308, 3620], 'STAT5/STAT1α': [114, 310], 'heterodimers,': [115, 311, 3560], 'bind': [116, 312, 1222, 1405, 1912, 3596], 'prolactin-inducible': [119, 315, 419, 505, 3891, 3977], 'element': [120, 316, 1409], 'β-casein': [123, 319, 1606, 3614, 3683], 'promoter.': [124, 320], 'The': [125, 321, 392, 3665, 3864], 'activity': [128, 324, 799, 2252, 2757, 3546, 3671, 4271], 'Kit': [130, 326], 'appears': [131, 327, 1938, 2625], 'essential': [132, 328, 3795], 'for': [133, 329, 443, 529, 830, 2258, 2634, 2769, 2834, 2940, 2953, 2963, 2975, 3083, 3169, 3299, 3448, 3458, 3463, 3515, 3759, 3796, 3915, 4001, 4302], 'activation': [135, 160, 190, 331, 356, 386, 1125, 1806, 1885, 1931, 1937, 2044, 2153, 2575, 2830, 2864, 2984, 3014, 3086, 3368, 3798], 'since': [136, 332], 'kinase-defective': [138, 334, 2926], 'mutant': [139, 152, 335, 348, 424, 434, 510, 520, 1861, 2186, 2775, 3140, 3330, 3896, 3906, 3982, 3992], 'lacking': [140, 336, 425, 511, 2013, 2875, 3897, 3983], 'insert': [143, 339, 428, 514, 2016, 2528, 2591, 2696, 3900, 3986], 'domain': [144, 340, 826, 1201, 2640, 2697, 2795, 3407, 3418, 4298], 'was': [145, 165, 341, 361, 1527, 1685, 1836, 2867], 'inactive': [146, 342, 2142], 'signaling.': [149, 345], 'However,': [150, 346, 1863, 2516, 3164, 3285], 'another': [151, 347, 1418], 'lacked': [154, 350], 'carboxyl-terminal': [156, 352, 432, 518, 1928, 3904, 3990], 'region': [157, 353, 1929, 3373, 3685, 3695, 3791], 'retained': [158, 354], 'STAT1α': [159, 355, 1936, 2910, 3334, 3345, 3516, 3729, 3814], 'translocation': [163, 359, 3459], 'but': [164, 360, 1560, 2922, 3154, 3335, 3365, 3687, 3738, 3803], 'unable': [166, 362, 2147, 3150, 3276], 'fully': [168, 364], 'activate': [169, 365, 2262, 2782], 'although': [172, 368], 'it': [173, 369, 800, 2461, 2624, 4272], 'mediated': [174, 370, 764, 4236], 'transient': [176, 372], 'phosphorylation.': [177, 373], 'These': [178, 374, 1593], 'results': [179, 375, 2008, 2904, 3769], 'indicate': [180, 376], 'different': [182, 378, 1237, 1559, 1829, 1970, 1981, 3020, 3078, 3350, 3712, 3776], 'domains': [184, 380, 836, 2592, 4308], 'involved': [188, 384, 3781], 'various': [193, 389, 3840], 'proteins.': [195, 391, 1670, 1965, 3163], 'stem': [393, 402, 488, 3865, 3874, 3960], '1The': [397, 483, 3869, 3955], 'abbreviations': [398, 484, 3870, 3956], 'used': [399, 485, 3871, 3957], 'are:': [400, 486, 3872, 3958], 'SCF,': [401, 487, 3873, 3959], 'factor;': [404, 490, 3876, 3962], 'IL-3,': [405, 491, 3877, 3963], 'interleukin-3;': [406, 492, 3878, 3964], 'STATs,': [407, 493, 3879, 3965], 's': [408, 494, 3880, 3966], 'transcription;': [414, 500, 3886, 3972], 'SIE,': [415, 501, 3887, 3973], 'serum-inducible': [416, 502, 1408, 3888, 3974], 'element;': [417, 420, 503, 506, 3889, 3892, 3975, 3978], 'PIE,': [418, 504, 3890, 3976], 'ΔKI,': [421, 507, 3893, 3979], 'domain;': [429, 515, 3901, 3987], 'ΔCT,': [430, 516, 3902, 3988], 'deletion': [433, 519, 1971, 3905, 3991], 'c-Kit;': [436, 522, 3908, 3994], 'HRS,': [437, 523, 3909, 3995], 'NIH-3T3': [438, 524, 3910, 3996], 'transfected': [440, 526, 1820, 3912, 3998], 'selected': [442, 528, 3914, 4000], 'overexpression': [444, 530, 3916, 4002], 'human': [447, 451, 533, 537, 1878, 1998, 3919, 3923, 4005, 4009], 'cDNA;': [449, 535, 3921, 4007], 'MO7e,': [450, 536, 1882, 3922, 4008], 'growth': [452, 465, 469, 481, 538, 551, 555, 567, 811, 1813, 3862, 3924, 3937, 3941, 3953, 4010, 4023, 4027, 4039, 4283], 'factor-dependent': [453, 539, 1814, 3925, 4011], 'megakaryoblastic': [454, 540, 3926, 4012], 'line;': [456, 542, 3928, 4014], 'Pipes,': [457, 543, 3929, 4015], '1,4-piperazinediethanesulfonic': [458, 544, 3930, 4016], 'acid;': [459, 545, 3931, 4017], 'PAGE,': [460, 546, 3932, 4018], 'polyacrylamide': [461, 547, 3933, 4019], 'gel': [462, 548, 3934, 4020], 'electrophoresis;': [463, 549, 3935, 4021], 'GH,': [464, 550, 3936, 4022], 'hormone;': [466, 552, 3938, 4024], 'PDGFR,': [467, 553, 3939, 4025], 'platelet-derived': [468, 554, 810, 3940, 4026, 4282], 'receptor;': [471, 557, 3943, 4029], 'CSF,': [472, 558, 3944, 4030], 'colony-stimulating': [473, 559, 701, 706, 817, 3945, 4031, 4173, 4178, 4289], 'factor-1;': [474, 560, 3946, 4032], 'SH2,': [475, 561, 3947, 4033], 'Src': [476, 562, 833, 3948, 4034, 4305], 'homology': [477, 563, 834, 3949, 4035, 4306], '2;': [478, 564, 3950, 4036], 'EGF,': [479, 565, 3951, 4037], 'epidermal': [480, 566, 3952, 4038], 'has': [569, 1315, 1772, 2570, 2831, 2960, 3550, 4041], 'been': [570, 1249, 1316, 1773, 2571, 2832, 2961, 3551, 4042], 'implicated': [571, 1443, 3311, 4043], 'important': [576, 4048], 'developmental': [577, 4049], 'processes': [578, 4050], '(1Zsebo': [579, 718, 4051, 4190], 'K.M.': [580, 719, 4052, 4191], 'Wypych': [581, 720, 4053, 4192], 'J.': [582, 625, 669, 721, 853, 859, 883, 909, 1003, 1042, 1155, 1277, 1395, 1547, 1584, 1615, 1648, 1703, 1784, 2079, 2285, 2304, 2328, 2349, 2389, 2427, 2478, 2647, 2664, 2715, 2721, 2846, 2887, 2995, 3099, 3194, 3475, 3630, 4054, 4097, 4141, 4193, 4325, 4331], 'Mc': [583, 722, 4055, 4194], 'Niece': [584, 723, 4056, 4195], 'I.K.': [585, 724, 4057, 4196], 'Lu': [586, 725, 4058, 4197], 'H.S.': [587, 641, 726, 4059, 4113, 4198], 'Smith': [588, 727, 4060, 4199], 'K.A.': [589, 728, 4061, 4200], 'Karkare': [590, 729, 4062, 4201], 'S.B.': [591, 730, 4063, 4202], 'Sachdev': [592, 731, 4064, 4203], 'R.K.': [593, 732, 4065, 4204], 'Yuschenkoff': [594, 733, 4066, 4205], 'V.N.': [595, 601, 734, 740, 4067, 4073, 4206, 4212], 'Birkett': [596, 735, 4068, 4207], 'N.C.': [597, 736, 2166, 2405, 4069, 4208], 'Williams': [598, 737, 947, 4070, 4209], 'L.R.': [599, 738, 4071, 4210], 'Satyagal': [600, 739, 4072, 4211], 'Tung': [602, 741, 4074, 4213], 'W.': [603, 742, 2340, 4075, 4214], 'Bosselman': [604, 743, 4076, 4215], 'R.A.': [605, 744, 4077, 4216], 'Mendiaz': [606, 745, 4078, 4217], 'E.A.': [607, 746, 4079, 4218], 'Langley': [608, 747, 4080, 4219], 'K.E.': [609, 748, 4081, 4220], 'Cell.': [610, 648, 678, 749, 958, 1020, 2170, 2409, 2435, 3432, 4082, 4120, 4150, 4221], '1990;': [611, 649, 679, 750, 4083, 4121, 4151, 4222], '63:': [612, 650, 680, 751, 4084, 4122, 4152, 4223], '195-201Abstract': [613, 752, 4085, 4224], 'Full': [614, 652, 682, 753, 1009, 1048, 1110, 1182, 1184, 1260, 1304, 1306, 2062, 2106, 2108, 2355, 2357, 2670, 2672, 2852, 2854, 2893, 2895, 3001, 3003, 3105, 3107, 3200, 3436, 3636, 3638, 4086, 4124, 4154, 4225], 'Text': [615, 653, 683, 754, 1010, 1049, 1111, 1183, 1185, 1261, 1305, 1307, 2063, 2107, 2109, 2356, 2358, 2671, 2673, 2853, 2855, 2894, 2896, 3002, 3004, 3106, 3108, 3201, 3437, 3637, 3639, 4087, 4125, 4155, 4226], 'PDF': [616, 654, 684, 755, 1011, 1050, 1112, 1186, 1262, 1308, 2064, 2110, 2359, 2674, 2856, 2897, 3005, 3109, 3202, 3438, 3640, 4088, 4126, 4156, 4227], 'PubMed': [617, 655, 685, 756, 863, 887, 914, 963, 984, 1012, 1025, 1051, 1075, 1113, 1159, 1171, 1187, 1263, 1281, 1293, 1309, 1359, 1382, 1401, 1435, 1470, 1498, 1519, 1551, 1588, 1619, 1652, 1750, 2065, 2083, 2095, 2111, 2175, 2211, 2310, 2334, 2360, 2395, 2414, 2440, 2485, 2560, 2607, 2653, 2675, 2725, 2746, 2815, 2857, 2898, 3006, 3110, 3203, 3227, 3269, 3439, 3479, 3530, 3581, 3641, 4089, 4127, 4157, 4228, 4335], 'Scopus': [618, 656, 686, 757, 864, 888, 902, 915, 964, 985, 1026, 1114, 1160, 1172, 1188, 1264, 1282, 1294, 1310, 1360, 1383, 1436, 1471, 1499, 1520, 1552, 1589, 1620, 1653, 1707, 1751, 2066, 2084, 2096, 2112, 2176, 2212, 2361, 2415, 2441, 2486, 2561, 2608, 2676, 2726, 2747, 2816, 2858, 2899, 3007, 3111, 3270, 3440, 3480, 3531, 3582, 3642, 4090, 4128, 4158, 4229, 4336], '(654)': [619, 758, 4091, 4230], 'Google': [620, 658, 688, 759, 866, 890, 904, 917, 966, 987, 1013, 1028, 1052, 1076, 1116, 1162, 1174, 1190, 1266, 1284, 1296, 1312, 1362, 1385, 1402, 1438, 1473, 1501, 1522, 1554, 1591, 1622, 1655, 1709, 1753, 1794, 2068, 2086, 2098, 2114, 2178, 2214, 2294, 2311, 2335, 2363, 2396, 2417, 2443, 2488, 2514, 2563, 2610, 2654, 2678, 2728, 2749, 2818, 2860, 2901, 3009, 3044, 3074, 3113, 3204, 3228, 3272, 3394, 3442, 3482, 3533, 3584, 3644, 4092, 4130, 4160, 4231, 4338], 'Scholar,': [621, 659, 867, 891, 905, 967, 988, 1014, 1029, 1053, 1163, 1175, 1267, 1285, 1297, 2069, 2087, 2099, 2336, 2397, 2489, 2655, 2729, 3205, 4093, 4131, 4339], '2Williams': [622, 4094], 'D.E.': [623, 948, 2431, 4095], 'Eismman': [624, 4096], 'Baird': [626, 4098], 'A.': [627, 857, 895, 956, 980, 1355, 1466, 1483, 1494, 1582, 1646, 1701, 1746, 2207, 2495, 2556, 2661, 2719, 2742, 2880, 3092, 3625, 3627, 4099, 4329], 'Rauch': [628, 4100], 'C.': [629, 998, 1339, 1782, 2476, 4101], 'van-Ness': [630, 4102], 'K.': [631, 663, 873, 1457, 1508, 2281, 2596, 2992, 3258, 3262, 3420, 4103, 4135, 4345], 'March': [632, 4104], 'C.J.': [633, 2843, 3034, 3064, 3384, 4105], 'Park': [634, 4106], 'L.S.': [635, 4107], 'Martin': [636, 4108], 'U.': [637, 855, 978, 1353, 1464, 1492, 1744, 2205, 2554, 2717, 2740, 3623, 4109, 4327], 'Mochizuki': [638, 4110], 'D.Y.': [639, 4111], 'Boswell': [640, 4112], 'Burgess': [642, 4114], 'G.S.': [643, 2472, 4115], 'Cosman': [644, 4116], 'D.': [645, 673, 971, 1070, 2164, 2198, 2403, 2547, 2733, 3222, 3428, 4117, 4145], 'Lyman': [646, 949, 4118], 'S.D.': [647, 950, 4119], '167-174Abstract': [651, 4123], '(770)': [657, 4129], '3Huang': [660, 4132], 'E.': [661, 851, 2713, 4133, 4323], 'Nocka': [662, 4134], 'Beier': [664, 4136], 'D.R.': [665, 4137], 'Chu': [666, 4138], 'T.Y.': [667, 4139], 'Buck': [668, 4140], 'Lahm': [670, 4142], 'H.W.': [671, 4143], 'Wellner': [672, 4144], 'Leder': [674, 4146], 'P.': [675, 677, 871, 881, 4147, 4149, 4343], 'Besmer': [676, 880, 4148], '225-233Abstract': [681, 4153], '(939)': [687, 4159], 'Scholar)': [689, 1386, 1403, 1623, 2295, 2312, 4161], 'is': [691, 1123, 1524, 1602, 1675, 2130, 2146, 2256, 2451, 2531, 2580, 2632, 2942, 2987, 3149, 3177, 3356, 3446, 3714, 3757, 3794, 4163], 'potent': [693, 4165], 'co-stimulating': [694, 4166], 'protein': [695, 1081, 1805, 4167], 'acts': [697, 4169], 'synergistically': [698, 4170], 'factors,': [702, 4174], 'such': [703, 808, 934, 1119, 1451, 4175, 4280], 'granulocyte-macrophage': [705, 4177], 'interleukin-3': [709, 4181], '(IL-3),': [710, 4182], 'promote': [712, 4184], 'early': [715, 4187], 'Scholar).': [760, 918, 1117, 1191, 1313, 1363, 1439, 1592, 1754, 2115, 2179, 2364, 2444, 2515, 2611, 2679, 2819, 2861, 2902, 3010, 3075, 3273, 3443, 3483, 3585, 3645, 4232], 'effects': [762, 3856, 4234], 'presence,': [767, 4239], 'on': [768, 1193, 2582, 2915, 3016, 3122, 3349, 4240], 'surface': [770, 4242], 'target': [773, 1232, 4245], 'transmembrane': [777, 4249], 'receptor': [778, 781, 787, 813, 923, 1446, 1720, 1826, 1853, 1944, 2038, 2242, 2255, 2791, 2837, 2873, 2927, 2949, 2958, 2968, 3030, 3240, 3380, 3455, 3537, 4250, 4253, 4259, 4285], 'c-Kit.': [779, 2034, 4251], 'belongs': [782, 4254], 'family,': [788, 807, 4260, 4279], 'addition': [791, 4263], 'presence': [794, 822, 3018, 4266, 4294], 'an': [796, 824, 1323, 4268, 4296], 'intrinsic': [797, 4269], 'enzymatic': [798, 2251, 4270], 'shares': [801, 4273], 'other': [803, 1633, 1664, 1864, 3165, 3306, 3570, 3609, 4275], 'members': [804, 4276], '(PDGFR)': [814, 4286], 'factor-1': [818, 4290], '(CSF-1)': [819, 4291], 'interkinase': [825, 4297], 'consensus': [828, 2628, 2682, 4300], 'sequences': [829, 1337, 2614, 4301], 'recognition': [831, 4303], '2': [835, 4307], '(SH2)': [837, 4309], '(4Yarden': [838, 2700, 4310], 'Y.': [839, 893, 907, 973, 1039, 2200, 2549, 2701, 2735, 3191, 3246, 3260, 4311], 'Kuang': [840, 2702, 4312], 'W.J.': [841, 1739, 2703, 4313], 'Yang-Feng': [842, 2704, 4314], 'T.': [843, 954, 990, 1000, 1016, 1343, 1481, 1697, 1699, 2279, 2501, 2705, 3250, 3256, 3264, 4315], 'Coussens': [844, 2706, 4316], 'L.': [845, 1041, 1514, 2602, 2707, 3193, 3629, 4317], 'Munemitsu': [846, 2708, 4318], 'S.': [847, 877, 969, 979, 1057, 1149, 1271, 1354, 1455, 1459, 1465, 1493, 1506, 1745, 2073, 2196, 2206, 2346, 2421, 2545, 2555, 2594, 2659, 2709, 2731, 2741, 3209, 3469, 4319, 4349], 'Dull': [848, 2710, 4320], 'T.J.': [849, 2711, 4321], 'Chen': [850, 1456, 2712, 4322], 'Schlessinger': [852, 908, 2426, 2714, 4324], 'Francke': [854, 2716, 4326], 'Ullrich': [856, 894, 2660, 2718, 4328], 'EMBO': [858, 882, 1546, 1583, 1614, 1647, 1702, 2720, 4330], '1987;': [860, 911, 2722, 4332], '6:': [861, 2723, 4333], '3341-3351Crossref': [862, 2724, 4334], '(1317)': [865, 2727, 4337], '5Qiu': [868, 4340], 'F.': [869, 1543, 1611, 2882, 3094, 4341], 'Ray': [870, 4342], 'Brown': [872, 4344], 'Barker': [874, 4346], 'P.E.': [875, 4347], 'Jhanwar': [876, 4348], 'Ruddle': [878, 4350], 'F.H.': [879, 4351], '1988;': [884, 899], '7:': [885, 1180, 1302, 2104], '1003-1011Crossref': [886], '(566)': [889], '6Yarden': [892], 'Annu.': [896], 'Rev.': [897], 'Biochem.': [898], '57:': [900], '433-478Crossref': [901], '(1384)': [903], '7Yarden': [906], 'Biochemistry.': [910], '26:': [912], '1434-1442Crossref': [913], '(376)': [916], 'transphosphorylation,': [927], 'increased': [929], 'SH2-containing': [932], 'phospholipase': [936], 'C-γ,': [937], 'phosphatidylinositol': [938, 2542], '3-kinase,': [939], 'Syp,': [940], 'JAK2': [942, 2224, 3174], '(8Rottapel': [943], 'R.': [944, 996, 1345, 2480, 2491, 2497, 2507], 'Reedijk': [945], 'M.': [946, 2283, 2289, 2886, 3098, 3248, 3252], 'Anderson': [951], 'D.M.': [952], 'Pawson': [953, 999], 'Bernstein': [955], 'Mol.': [957, 1019, 2169, 2408, 2434, 3039, 3069, 3389], 'Biol.': [959, 1004, 1021, 1043, 2171, 2350, 2410, 2436, 2665, 2847, 2888, 2996, 3100, 3195, 3631], '1991;': [960], '11:': [961, 1108, 1258, 2060], '3043-3051Crossref': [962], '(201)': [965], '9Lev': [968, 2730], 'Givol': [970, 2197, 2546, 2732], 'Yarden': [972, 1038, 2199, 2548, 2734, 3190], 'Proc.': [974, 1349, 1460, 1488, 1740, 2201, 2550, 2736], 'Natl.': [975, 1350, 1461, 1489, 1741, 2202, 2551, 2737], 'Acad.': [976, 1351, 1462, 1490, 1742, 2203, 2552, 2738], 'Sci.': [977, 1352, 1463, 1491, 1743, 2204, 2553, 2739], '1992;': [981, 1356, 2208, 2557, 2743], '89:': [982, 1357, 2209, 2558, 2744], '678-682Crossref': [983, 2210, 2559, 2745], '(90)': [986, 2213, 2562, 2748], '10Tauchi': [989], 'Feng': [991], 'G.-S.': [992], 'Marshall': [993], 'M.S.': [994], 'Shen': [995], 'Mantel': [997], 'Broxmeyer': [1001], 'H.E.': [1002, 1394, 2303, 2327, 2388, 2646], 'Chem.': [1005, 1044, 2351, 2666, 2848, 2889, 2997, 3101, 3196, 3632], '1994;': [1006, 1045, 1379, 1432, 1548, 1616, 3197, 3433], '269:': [1007, 1046, 2483, 3198], '25206-25211Abstract': [1008], '11Yi': [1015], 'Ihle': [1017, 2347], 'J.N.': [1018, 1102, 1252, 2054, 2348], '1993;': [1022, 3578], '13:': [1023, 1549, 1617], '3350-3358Crossref': [1024], '(234)': [1027, 3583], '12Brizzi': [1030], 'M.F.': [1031, 3183], 'Zini': [1032, 3184], 'M.G.': [1033, 1035, 3185, 3187], 'Aronica': [1034, 3186], 'Blechman': [1036, 3188], 'J.M.': [1037, 3189], 'Pegoraro': [1040, 3192], '31680-31684Abstract': [1047, 3199], '13Weiler': [1054, 3206], 'S.R.': [1055, 3207], 'Mou': [1056, 3208], 'De': [1058, 3210], 'Berry': [1059, 3211], 'C.S.': [1060, 3212], 'Keller': [1061, 3213], 'J.R.': [1062, 3214], 'Ruscetti': [1063, 3215], 'F.W.': [1064, 2338, 3216], 'Ferris': [1065, 3217], 'D.K.': [1066, 3218], 'Longo': [1067, 3219], 'D.L.': [1068, 3220], 'Linnekin': [1069, 3221], 'Blood.': [1071, 3223], '1996;': [1072, 1156, 1278, 1495, 1747, 2080, 2172, 2291, 2411, 2437, 2849, 3041, 3071, 3224, 3391, 3476, 3633], '87:': [1073, 3225], '3688-3693Crossref': [1074, 3226], 'Scholar).The': [1077], 'JAKs': [1078, 1122, 2370], 'non-transmembrane': [1080], 'kinases': [1083], 'rapidly': [1086], 'tyrosine-phosphorylated': [1087, 3021, 3079, 3124, 3399], 'ligand': [1089, 2020, 2040], 'critical': [1094], 'function': [1096, 1120, 3231], 'downstream': [1097], 'cytokine': [1099, 1144, 2037], 'receptors': [1100, 2313, 2317], '(14Ihle': [1101, 1251, 2053], 'Kerr': [1103, 1253, 2055, 2428, 3519], 'I.M.': [1104, 1254, 2056, 2429, 3520], 'Trends': [1105, 1255, 2057], 'Genet.': [1106, 1256, 2058], '1995;': [1107, 1257, 1467, 1585, 1649, 1704, 2059, 2352, 2482, 2667, 2998, 3527], '69-74Abstract': [1109, 1259, 2061], '(818)': [1115, 1265, 2067, 2487], 'One': [1118], '(signal': [1129], 'transcription),': [1134], 'latent': [1135], 'cytoplasmic': [1136, 2973, 3025, 3135, 3376], 'undergo': [1139, 1909, 3401], 'rapid': [1140, 2043], 'following': [1143, 2907], '(15Leaman': [1146, 3466], 'D.W.': [1147, 1269, 2071, 2419, 3467], 'Leung': [1148, 1270, 2072, 3468], 'Li': [1150, 1272, 2074, 3470], 'X.': [1151, 1273, 2075, 2841, 3032, 3062, 3382, 3471], 'Stark': [1152, 1274, 2076, 2432, 3472, 3521], 'G.R.': [1153, 1275, 2077, 2433, 3473, 3522], 'FASEB': [1154, 1276, 2078, 3474], '10:': [1157, 1279, 2081, 3042, 3072, 3392, 3477], '1578-1588Crossref': [1158, 1280, 2082, 3478], '(271)': [1161, 1283, 2085, 3481], '16Darnell': [1164, 1286, 2088], 'Jr.,': [1165, 1287, 1347, 1376, 1429, 2089, 2809, 3430, 3524], 'J.E.': [1166, 1288, 1348, 1377, 1430, 2090, 2810, 3431, 3525], 'Science.': [1167, 1289, 1378, 1431, 2091, 2481, 2811, 3526], '1997;': [1168, 1179, 1290, 1301, 1791, 2092, 2103, 2511, 2812, 2890, 3102, 3266], '277:': [1169, 1291, 2093, 2813], '1630-1635Crossref': [1170, 1292, 2094, 2814], '(3346)': [1173, 1295, 2097, 2817], "17O'Shea": [1176, 1298, 2100], 'J.J.': [1177, 1299, 1776, 2101, 2845, 3038, 3068, 3388], 'Immunity.': [1178, 1300, 2102], '1-11Abstract': [1181, 1303, 2105], '(343)': [1189, 1311, 2113], 'Phosphorylation': [1192], 'immediately': [1196], 'distal': [1197], 'SH2': [1200, 2639, 2794, 3406, 3417], 'homo-': [1204, 3558], 'heterodimerization': [1206], 'through': [1207, 3241, 3404], 'phosphotyrosine-SH2': [1208], 'interactions.': [1209], 'As': [1210], 'consequence': [1212], 'they': [1213], 'acquire': [1214], 'activity,': [1217], 'translocate': [1218], 'into': [1219, 3847], 'nucleus,': [1221], 'promoter': [1225, 1607, 3600, 3615, 3684, 3694], 'elements,': [1226], 'control': [1228], 'expression': [1230], 'genes.': [1233], 'So': [1234], 'far': [1235, 3716], 'seven': [1236], '(STAT1,': [1240], 'STAT2,': [1241, 1868], 'STAT3,': [1242, 1869], 'STAT4,': [1243, 1870], 'STAT5B,': [1245, 3822], 'STAT6)': [1247], 'have': [1248], 'cloned': [1250], '15Leaman': [1268, 2070], 'STAT1': [1314, 1364, 2150, 2272, 2382, 2981, 3367], 'originally': [1317, 1528], 'identified': [1318], 'component': [1321], 'interferon-activated': [1324], 'transcriptional': [1325, 1594, 3764], 'homodimerization': [1332], 'GAS': [1336], '(18Schindler': [1338], 'Fu': [1340], 'X.Y.': [1341], 'Improte': [1342], 'Aebersold': [1344], 'Darnell': [1346, 1375, 1428, 3429, 3523], '7836-7839Crossref': [1358], '(541)': [1361], 'can': [1365, 2273, 2318, 2462, 2978, 3141, 3167, 3505, 3815], 'also': [1366, 1625, 2565, 2943, 3540, 3562, 3746, 3816], 'be': [1367, 1940, 3055, 3310, 3506, 3698], 'activated': [1368, 1990, 3178, 3755, 3767, 3841], 'EGF': [1370, 1453, 2277, 2377], '(19Zhong': [1371, 1424], 'Z.': [1372, 1374, 1425, 1427], 'Wen': [1373, 1426], '264:': [1380, 1433], '95-98Crossref': [1381, 1434], '(1692)': [1384, 1437], 'PDGF': [1388, 1504, 2157, 2297, 2379, 2579, 3591], '(20Choudhury': [1389, 2298, 2322, 2383, 2641], 'G.G.': [1390, 2299, 2323, 2384, 2642], 'Ghosh-Choudhury': [1391, 2300, 2324, 2385, 2643], 'N.': [1392, 1580, 1644, 2301, 2325, 2386, 2644], 'Abbound': [1393, 2302, 2326, 2387, 2645], 'Clin.': [1396, 2305, 2329, 2390, 2648], 'Invest.': [1397, 2306, 2330, 2391, 2649], '1998;': [1398, 1516, 2307, 2331, 2392, 2604, 2650], '101:': [1399, 2308, 2332, 2393, 2651], '2751-2760Crossref': [1400, 2309, 2333, 2394, 2652], '(SIE)': [1410], 'c-Fos': [1412, 3599, 3693], 'homodimers': [1414, 3604, 3618], 'heterodimers': [1416, 3568, 3594, 3621, 3657, 3818], 'member': [1420], 'defined': [1421, 1568], 'STAT3': [1423, 2152, 2454, 2464, 2983], 'A': [1440, 2680], 'third': [1441], 'pathway,': [1450, 2139], '(21Ruff-Jamison': [1454], 'Cohen': [1458, 2345], '92:': [1468], '4215-4218Crossref': [1469], '(134)': [1472], 'Scholar),': [1474, 1502, 1523, 1555, 1656, 1710, 2215, 2564, 2750, 3045, 3114, 3229, 3534], 'ErbB-1': [1475], '(22Mellitzer': [1476], 'G.': [1477], 'Wessely': [1478], 'O.': [1479, 1510, 2598], 'Decker': [1480], 'Meinke': [1482], 'Hayman': [1484], 'M.J.': [1485], 'Beug': [1486], 'H.': [1487, 1541, 1576, 1609, 1640, 1695, 1778, 3254], '93:': [1496, 1748], '9600-9605Crossref': [1497], '(34)': [1500], '(23Valgeirsdottir': [1505, 2593], 'Paukku': [1507, 2595], 'Silvennoinen': [1509, 2597], 'Heldin': [1511, 2599], 'C.-H.': [1512, 2600], 'Claesson-Welsh': [1513, 2601], 'Oncogene.': [1515, 2290, 2603, 3265], '16:': [1517, 2173, 2412, 2438, 2605], '505-515Crossref': [1518, 2606], '(68)': [1521, 2609], 'STAT5.': [1525], 'described': [1529, 3513], 'prolactin-responsive': [1532], 'mammary': [1537, 1635], 'gland': [1538], 'epithelium': [1539], '(24Wakao': [1540, 1608], 'Gouilleux': [1542, 1610], 'Groner': [1544, 1612], 'B.': [1545, 1613, 2344], '2182-2191Crossref': [1550, 1618], '(712)': [1553, 1621], 'subsequently': [1557], 'two': [1558, 1828, 1919, 1969], 'highly': [1561], 'homologous': [1562], 'were': [1565, 1975, 1989, 3275, 3730], 'isolated': [1566], 'STAT5A': [1570, 3659, 3800, 3820], 'STAT5B': [1572, 1846, 1904, 1988, 3661, 3802], '(25Mui': [1573, 1637], 'A.L.-F.': [1574, 1638, 1693], 'Wakao': [1575, 1639, 1694], "O'Farrell": [1577, 1641], 'A.M.': [1578, 1642], 'Harada': [1579, 1643], 'Miyajima': [1581, 1645, 1700, 3626], '14:': [1586, 1650, 3267], '1166-1175Crossref': [1587, 1651], '(537)': [1590, 1654], 'factors': [1595], 'recognize': [1596], 'palindromic': [1599], 'sequence': [1600, 2683, 3679], 'found': [1603, 1833, 1978, 3648], 'promoters': [1630], 'genes': [1632, 1636], 'than': [1634, 1665, 2762, 3307], 'suggesting': [1657, 2751, 3115], 'may': [1660, 2237, 2767, 3054, 3230, 3297, 3309, 3539, 3561, 3843], 'induction': [1667], 'milk': [1669], 'Consistent': [1671, 1890, 2135, 2264], 'this': [1673, 1943, 2266, 3300], 'hypothesis': [1674, 2267], 'observation': [1677, 2518, 3171, 3719], 'dominant': [1680, 2803], 'negative': [1681], 'variant': [1682], 'able': [1686, 1837, 2934], 'inhibit': [1688], 'IL-3-mediated': [1689], '(26Mui': [1692], 'Kinoshita': [1696], 'Kitamura': [1698], '15:': [1705], '2425-2433Crossref': [1706], '(375)': [1708], 'mutation': [1713], 'residues': [1716, 2618, 2788, 2824, 3022, 3080, 3132, 3244], 'IL-2': [1719], 'β': [1721, 2587], 'chain,': [1722], 'mediating': [1723, 2619, 2826], 'docking': [1725, 2621, 2828, 2938, 3125], 'activation,': [1727, 2623], 'strongly': [1728], 'reduced': [1729], '(27Friedmann': [1732], 'M.C.': [1733], 'Migone': [1734], 'T.S.': [1735], 'Russell': [1736], 'S.M.': [1737], 'Leonard': [1738], '2077-2082Crossref': [1749], '(168)': [1752], 'Moreover,': [1755, 2006, 2365, 3807], 'potential': [1757], 'response': [1764, 1808, 1887, 1992, 2155, 3088, 3587, 3858], 'bone': [1766], 'marrow-derived': [1767], 'mast': [1768], 'reported': [1774, 2833, 2962, 3552], '(28Ryan': [1775], 'Huang': [1777, 3423], 'McReynolds': [1779], 'L.J.': [1780], 'Shelburne': [1781], 'Hu-Li': [1783], 'Huff': [1785], 'T.F.': [1786], 'Paul': [1787], 'W.E.': [1788], 'Exp.': [1789], 'Hematol.': [1790], '25:': [1792], '357-362PubMed': [1793], 'Scholar).In': [1795], 'present': [1797, 1875, 1947, 3411, 3772], 'study': [1798, 1948, 3773], 'investigated': [1800, 1950], 'pattern': [1802], 'MO7e': [1815, 2000], 'line': [1817, 1881], 'wild': [1824, 1851], 'type': [1825, 1852, 1967], 'mutants.': [1831], 'We': [1832, 1977, 3274], 'induce': [1839, 1956, 2024], 'carboxyl-terminally': [1859], 'deleted': [1860, 3147], '(ΔCT).': [1862], 'e.g.': [1867], 'STAT6,': [1872], 'which': [1873, 2189, 2530, 3176, 3363, 3492], 'underwent': [1883], 'no': [1884, 3500], 'SCF.': [1889], 'regulation': [1895], 'gene': [1897, 3119], 'expression,': [1898], 'modified': [1900], 'acquired': [1905], 'ability': [1907, 1952, 2375, 3158, 3326], 'dimerization': [1910, 3403, 3445, 3542], 'Analysis': [1917], 'mutants': [1920, 1972, 2874, 2969], 'attributed': [1923], 'whereas': [1935, 3602], 'independent': [1941], 'domain.DISCUSSIONIn': [1945], 'Wild': [1966], 'examined.': [1976], 'that,': [1979, 2246, 3511], 'among': [1980], 'only': [1984], 'both': [1996], 'c-Kit-transfected': [2004], 'fibroblasts.': [2005], 'obtained': [2009], 'mutant,': [2012, 3491], 'domain,': [2017, 2529], 'demonstrated': [2018], 'failed': [2022], 'mutated': [2033], 'In': [2035, 2965, 3011, 3586], 'family': [2039], 'JAK': [2046, 2125], 'leading': [2048], 'By': [2116], 'contrast,': [2117, 3012], 'receptors,': [2121], 'yet': [2132], 'clearly': [2133], 'defined.': [2134], 'JAK-independent': [2138], 'catalytically': [2141, 2931], 'PDGFR': [2145, 2586], 'stimulate': [2149], '(36Vignais': [2159], 'M.L.': [2160, 2399], 'Sadowski': [2161, 2400], 'H.B.': [2162, 2401, 3574], 'Watling': [2163, 2402], 'Rogers': [2165, 2404], 'Gilman': [2167, 2406, 3575], 'M.Z.': [2168, 2407, 3576], '1759-1769Crossref': [2174, 2413], '(218)': [2177, 2416], 'Likewise,': [2180, 3076], 'our': [2181, 2517, 3170], 'finding': [2182], 'ΔKI': [2185, 2774], 'displayed': [2190], 'reduction': [2191, 2753], 'autophosphorylation': [2193], 'vitro(9Lev': [2195], 'cannot': [2216, 3287], '(Fig.': [2220], '2)': [2221], 'treatment': [2227], '(data': [2228, 3282], 'shown),': [2230], 'supports': [2231, 3743], 'possibility': [2233, 2524, 3291, 3510, 3745], 'represent': [2238], 'direct': [2239], 'substrates': [2240], 'kinases,': [2244, 3305], 'indeed,': [2247], 'full': [2249, 3117, 3797], 'functional': [2250], 'required': [2257, 2633, 2944, 3082, 3447, 3851], 'coupling': [2259], 'STATs.': [2263], 'observations': [2270], 'directly': [2274], 'interact': [2275, 2535, 2779], '(37Okimoto': [2278], 'Kohno': [2280], 'Kuwano': [2282], 'Gopas': [2284], 'Kung': [2286], 'H.F.': [2287], 'Ono': [2288], '12:': [2292], '1625-1633PubMed': [2293], 'these': [2316, 3162, 3673, 3702, 3711], 'phosphorylate': [2319, 2381, 2463, 3161], 'STAT1in': [2320], 'vitro': [2321, 2466], '38Quelle': [2337], 'Thierfelder': [2339], 'Witthuhn': [2341], 'B.A.': [2342], 'Tang': [2343], '270:': [2353, 2668, 2999], '20775-20780Abstract': [2354], '(137)': [2362], 'absence': [2367], 'any': [2369, 3279], 'does': [2371, 2519, 2684], 'affect': [2373], '36Vignais': [2398], 'Scholar,39Leaman': [2418], 'Pisharody': [2420], 'Flickinger': [2422], 'T.W.': [2423], 'Commane': [2424], 'M.A.': [2425], 'Levy': [2430], '369-375Crossref': [2439], '(206)': [2442], 'Furthermore,': [2445, 2951], 'non-receptor': [2447, 3303], 'kinase,': [2449], 'Src,': [2450], 'associated': [2452], 'vivo': [2456], 'vitro,': [2459], '(40Yu': [2467], 'C.L.': [2468, 2493], 'Meyer': [2469], 'D.J.': [2470, 2503], 'Campbell': [2471], 'Larner': [2473], 'A.C.': [2474], 'Carter-Su': [2475], 'Schwartz': [2477], 'Jove': [2479, 2506], '81-83Crossref': [2484], '41Garcia': [2490], 'Yu': [2492], 'Hundnall': [2494], 'Catlett': [2496], 'Nelson': [2498], 'K.L.': [2499], 'Smithgall': [2500], 'Fijita': [2502], 'Ethier': [2504], 'S.P.': [2505], 'Cell': [2508], 'Growth': [2509], 'Differ.': [2510], '8:': [2512], '1267-1276PubMed': [2513], 'rule': [2521, 3288], 'out': [2522, 3289], 'known': [2532], 'selectively': [2534], 'p85': [2538], 'regulatory': [2539], 'subunit': [2540], '3-kinase': [2543], '(9Lev': [2544], 'contains': [2566], 'STAT-binding': [2567], 'sites.': [2568, 3126], 'It': [2569], 'recently': [2572], 'shown': [2573], 'dependent': [2581], 'sites': [2584, 2974], 'juxtamembrane': [2588], 'Comparing': [2612], 'surrounding': [2615], "receptor's": [2616], 'YVDP': [2629], 'YLDP': [2631], '42Lebrun': [2656], 'J.-J.': [2657], 'Ali': [2658], 'Kelly': [2662, 2883, 3095], 'P.A': [2663], '10664-10670Abstract': [2669], '(159)': [2677], 'similar': [2681], 'surround': [2686], 'residue': [2688, 3052], '721': [2689], '730': [2691], 'contained': [2692], 'catalytic': [2756], 'rather': [2761], 'loss': [2763], 'residues,': [2766], 'account': [2768, 3168, 3298], 'inability': [2771], 'proteins.Tight': [2784], 'phosphotyrosine': [2787, 2823, 3410], 'seems': [2799], '(16Darnell': [2808], 'Requirement': [2820], 'GH': [2836, 2967, 2986, 3029, 3379], '(43Xu': [2838], 'B.C.': [2839, 3036, 3066, 3386], 'Wang': [2840], 'Darus': [2842, 3033, 3063, 3383], 'Kopchick': [2844, 3037, 3067, 3387], '271:': [2850, 3634], '19768-19773Abstract': [2851], '(46)': [2859], 'Similarly,': [2862, 3646], 'PRL-induced': [2863], 'abolished': [2868], 'PRL': [2872, 3090], 'all': [2876, 2972], 'tyrosines': [2878], '(44Pezet': [2879, 3091], 'Ferrag': [2881, 3093], 'P.A.': [2884, 3096], 'Edery': [2885, 3097], '272:': [2891, 3103], '25043-25050Abstract': [2892, 3104], '(76)': [2900, 3112], 'Our': [2903, 3484], 'demonstrate': [2905, 3774, 3809], 'stimulation,': [2909, 3592], 'phosphorylated': [2914, 2937, 3497], 'tyrosine,': [2916], 'physically': [2917], 'associate': [2918], 'full-length': [2921, 3736], 'indicating': [2928, 3046], 'active': [2932], 'provide': [2936, 3844], 'site': [2939], 'STAT,': [2941], 'family.': [2950], 'evidence': [2952, 3396], 'alternative': [2954], 'mechanisms': [2955], 'interaction': [2959, 3281, 3296, 3538, 3786], 'GH.': [2964], 'particular,': [2966], 'devoid': [2970], 'nonetheless': [2979], 'support': [2980], 'when': [2985], 'provided': [2988], '(45Wang': [2989], 'Y.-D.': [2990], 'Wong': [2991], 'Wood': [2993], 'W.I.': [2994], '7021-7024Abstract': [3000], '(77)': [3008], 'relies': [3015], 'tail': [3026, 3136, 3377], '(46Wang': [3031, 3061, 3381], 'Xu': [3035, 3065, 3385], 'Endocrinol.': [3040, 3070, 3390], '1249-1260PubMed': [3043, 3073, 3393], 'redundancy': [3049], 'requirement': [3053], 'employed': [3056], 'GH-mediated': [3058], 'maximal': [3084], 'STAT5-mediated': [3118], 'depends': [3121, 3348], 'several': [3123], 'Therefore,': [3127], 'lack': [3129], 'ΔCT': [3139, 3329, 3490], 'explain': [3142], 'why': [3143], 'SCF-activated': [3145], 'COOH-terminally': [3146], 'recruit': [3152, 3495], 'STAT5s': [3153], 'still': [3155], 'retains': [3156], 'transiently': [3160], 'models': [3166], 'itself,': [3175], '(12Brizzi': [3182], 'bridge,': [3234], 'bringing': [3235], '(47Fjetani': [3245], 'Hibi': [3247], 'Fukada': [3249], 'Takahashi': [3251], 'Hioshyda': [3253], 'Himaguchi': [3255], 'Sugiyama': [3257], 'Hiamanaka': [3259], 'Nakajima': [3261], 'Hirano': [3263], '751-761Crossref': [3268], '(141)': [3271], 'detect': [3278], 'JAK2-STAT5': [3280], 'shown).': [3284], 'weak': [3294], 'molecular': [3295], 'result.': [3301], 'Alternatively,': [3302], 'JAK2,': [3308], 'and/or': [3316], 'STAT-receptor': [3317], 'interaction.': [3318], 'Nevertheless,': [3319], 'independently': [3320], 'exact': [3323], 'mechanism,': [3324], 'suggests': [3340, 3397], 'recruitment': [3343], 'domains.': [3353], 'This': [3354, 3444], 'interpretation': [3355], 'agreement': [3358], 'model': [3361], 'requires': [3369], 'box': [3371], '3': [3372], 'Scholar).Accumulating': [3395], 'intermolecular': [3402], 'conserved': [3409], 'COOH-terminal': [3414, 3790], '(48Shuai': [3419], 'Horvath': [3421], 'C.M.': [3422], 'L.H.T.': [3424], 'Quereshi': [3425], 'S.A.': [3426], 'Cowburn': [3427], '76:': [3434], '821-828Abstract': [3435], '(677)': [3441], 'subsequent': [3449], 'release': [3450], 'from': [3453, 3766], 'complex': [3456, 3504, 3825], 'nucleus': [3462], 'result': [3485], 'demonstrates': [3486], 'fails': [3493], 'dimer': [3501, 3760], 'PIE': [3503, 3831], 'formed,': [3507], 'supporting': [3508], 'previously': [3514], '(49Heim': [3517], 'M.H.': [3518], '267:': [3528], '1347-1349Crossref': [3529], '(347)': [3532], 'dictate': [3541], 'proteins.It': [3549], 'besides': [3556], 'forming': [3557], 'contribute': [3563], 'formation': [3566, 3655, 3761], '(33Sadowski': [3573], 'Nature.': [3577], '362:': [3579], '79-83Crossref': [3580], 'CSF-1': [3589], 'STAT5/STAT3': [3593], 'apparently': [3595], 'region,': [3601], 'inactive.': [3606], 'On': [3607], 'hand,': [3610], 'occurs': [3616], '(35Novak': [3622], 'Mui': [3624], 'Paradiso': [3628], '18350-18354Abstract': [3635], '(53)': [3643], 'containing': [3658], 'together': [3662], 'STAT1α.': [3664, 3806], 'analysis': [3666], 'heterodimeric': [3674, 3704, 3722], 'complexes': [3675, 3723], 'revealed': [3676], 'corresponding': [3680, 3690], '(PIE),': [3686], '(SIE),': [3696], 'could': [3697], 'specifically': [3699, 3827], 'recognized': [3700], 'STAT5s/STAT1α': [3703], 'complexes.': [3705], 'Although': [3706], 'biological': [3708, 3855], 'significance': [3709], 'dimers': [3713], 'thus': [3715], 'unclear,': [3717], 'formed': [3724, 3826], 'detected': [3731], 'ΔCT-expressing': [3741], 'rate': [3749], 'dephosphorylation': [3751], 'already': [3754], 'molecules': [3756], 'final': [3763], 'output': [3765], 'STATs.The': [3768], 'regions': [3777], 'STAT1α-': [3783], 'STAT5-receptor': [3785], 'sequence.': [3832], 'Better': [3833], 'understanding': [3834], 'played': [3838], 'new': [3845], 'insights': [3846], 'pathways': [3850], 'achieve': [3853], 'divergent': [3854], 'same': [3861], 'factor.': [3863]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2134511166', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-10T10:12:03.676876', 'created_date': '2016-06-24'}