Foxa1 and Foxa2 Interact with the Androgen Receptor to Regulate Prostate and Epididymal Genes Differentially

Name: Work Video:
Duration: 3 min 30 s
Xiuping Yu; Aparna Gupta; Yongqing Wang; Kichiya Suzuki; Janni Mirosevich; Marie‐Claire Orgebin‐Crist; Robert J. Matusik
{'id': 'https://openalex.org/W2134170971', 'doi': 'https://doi.org/10.1196/annals.1336.009', 'title': 'Foxa1 and Foxa2 Interact with the Androgen Receptor to Regulate Prostate and Epididymal Genes Differentially', 'display_name': 'Foxa1 and Foxa2 Interact with the Androgen Receptor to Regulate Prostate and Epididymal Genes Differentially', 'publication_year': 2005, 'publication_date': '2005-12-01', 'ids': {'openalex': 'https://openalex.org/W2134170971', 'doi': 'https://doi.org/10.1196/annals.1336.009', 'mag': '2134170971', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16467259'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1196/annals.1336.009', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8802318', 'display_name': 'Annals of the New York Academy of Sciences', 'issn_l': '0077-8923', 'issn': ['0077-8923', '1749-6632'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048260193', 'display_name': 'Xiuping Yu', 'orcid': 'https://orcid.org/0000-0003-2844-7026'}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'XIUPING YU', 'raw_affiliation_strings': ['Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110563201', 'display_name': 'Aparna Gupta', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'APARNA GUPTA', 'raw_affiliation_strings': ['Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100673729', 'display_name': 'Yongqing Wang', 'orcid': 'https://orcid.org/0000-0001-8340-6003'}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'YONGQING WANG', 'raw_affiliation_strings': ['Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042556561', 'display_name': 'Kichiya Suzuki', 'orcid': 'https://orcid.org/0000-0001-5997-6567'}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'KICHIYA SUZUKI', 'raw_affiliation_strings': ['Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082583438', 'display_name': 'Janni Mirosevich', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}, {'id': 'https://openalex.org/I4387156432', 'display_name': 'Beckman Research Institute', 'ror': 'https://ror.org/05fazth07', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4387156432']}, {'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'JANNI MIROSEVICH', 'raw_affiliation_strings': ['Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Molecular Medicine, Beckman Research Institute at the City of Hope, Duarte, California 91010, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Molecular Medicine, Beckman Research Institute at the City of Hope, Duarte, California 91010, USA', 'institution_ids': ['https://openalex.org/I4387156432', 'https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110100370', 'display_name': 'Marie‐Claire Orgebin‐Crist', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'MARIE‐CLAIRE ORGEBIN‐CRIST', 'raw_affiliation_strings': ['Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5087285670', 'display_name': 'Robert J. Matusik', 'orcid': 'https://orcid.org/0000-0003-2057-9892'}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'ROBERT J. MATUSIK', 'raw_affiliation_strings': ['Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA'], 'affiliations': [{'raw_affiliation_string': 'Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}, {'raw_affiliation_string': 'Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA', 'institution_ids': ['https://openalex.org/I200719446']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5087285670'], 'corresponding_institution_ids': ['https://openalex.org/I200719446'], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.242, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 94, 'citation_normalized_percentile': {'value': 0.941183, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '1061', 'issue': '1', 'first_page': '77', 'last_page': '93'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12835', 'display_name': 'FOXO transcription factor regulation', 'score': 0.9848, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/foxa2', 'display_name': 'FOXA2', 'score': 0.990008}, {'id': 'https://openalex.org/keywords/foxa1', 'display_name': 'FOXA1', 'score': 0.96793723}, {'id': 'https://openalex.org/keywords/chromatin-immunoprecipitation', 'display_name': 'Chromatin immunoprecipitation', 'score': 0.7304579}], 'concepts': [{'id': 'https://openalex.org/C148397407', 'wikidata': 'https://www.wikidata.org/wiki/Q21107432', 'display_name': 'FOXA2', 'level': 4, 'score': 0.990008}, {'id': 'https://openalex.org/C154456304', 'wikidata': 'https://www.wikidata.org/wiki/Q18027046', 'display_name': 'FOXA1', 'level': 4, 'score': 0.96793723}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.73240215}, {'id': 'https://openalex.org/C134320426', 'wikidata': 'https://www.wikidata.org/wiki/Q901026', 'display_name': 'Chromatin immunoprecipitation', 'level': 5, 'score': 0.7304579}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5002065}, {'id': 'https://openalex.org/C2781254305', 'wikidata': 'https://www.wikidata.org/wiki/Q1973610', 'display_name': 'Epididymis', 'level': 3, 'score': 0.44416213}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.4172504}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.4161945}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.41503382}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.39162496}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3865052}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.37423378}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.32610375}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.2785187}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.19524652}, {'id': 'https://openalex.org/C2781087480', 'wikidata': 'https://www.wikidata.org/wiki/Q17145', 'display_name': 'Sperm', 'level': 2, 'score': 0.093609095}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.08573422}], 'mesh': [{'descriptor_ui': 'D004822', 'descriptor_name': 'Epididymis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D051541', 'descriptor_name': 'Hepatocyte Nuclear Factor 3-alpha', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D051542', 'descriptor_name': 'Hepatocyte Nuclear Factor 3-beta', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011467', 'descriptor_name': 'Prostate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011944', 'descriptor_name': 'Receptors, Androgen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000728', 'descriptor_name': 'Androgens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000728', 'descriptor_name': 'Androgens', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047369', 'descriptor_name': 'Chromatin Immunoprecipitation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004822', 'descriptor_name': 'Epididymis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051541', 'descriptor_name': 'Hepatocyte Nuclear Factor 3-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051542', 'descriptor_name': 'Hepatocyte Nuclear Factor 3-beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051542', 'descriptor_name': 'Hepatocyte Nuclear Factor 3-beta', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011467', 'descriptor_name': 'Prostate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011944', 'descriptor_name': 'Receptors, Androgen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018168', 'descriptor_name': 'Receptors, Retinoic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018168', 'descriptor_name': 'Receptors, Retinoic Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018168', 'descriptor_name': 'Receptors, Retinoic Acid', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D054839', 'descriptor_name': 'Retinol-Binding Proteins, Plasma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1196/annals.1336.009', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8802318', 'display_name': 'Annals of the New York Academy of Sciences', 'issn_l': '0077-8923', 'issn': ['0077-8923', '1749-6632'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16467259', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W140444695', 'https://openalex.org/W1489622884', 'https://openalex.org/W1920180838', 'https://openalex.org/W1931597824', 'https://openalex.org/W1964787551', 'https://openalex.org/W1986859673', 'https://openalex.org/W1990283480', 'https://openalex.org/W1991320426', 'https://openalex.org/W1993243592', 'https://openalex.org/W2003264741', 'https://openalex.org/W2005144583', 'https://openalex.org/W2009624062', 'https://openalex.org/W2011780626', 'https://openalex.org/W2030996195', 'https://openalex.org/W2043861102', 'https://openalex.org/W2045706913', 'https://openalex.org/W2047203795', 'https://openalex.org/W2050846683', 'https://openalex.org/W2060116181', 'https://openalex.org/W2064773277', 'https://openalex.org/W2065849075', 'https://openalex.org/W2071707735', 'https://openalex.org/W2083872949', 'https://openalex.org/W2100715279', 'https://openalex.org/W2115010303', 'https://openalex.org/W2116301885', 'https://openalex.org/W2122229386', 'https://openalex.org/W2128737197', 'https://openalex.org/W2134101564', 'https://openalex.org/W2145211396', 'https://openalex.org/W2145290390', 'https://openalex.org/W2154226543', 'https://openalex.org/W2163458728', 'https://openalex.org/W2396242620', 'https://openalex.org/W2469040080', 'https://openalex.org/W4255746720'], 'related_works': ['https://openalex.org/W2900421498', 'https://openalex.org/W2159228663', 'https://openalex.org/W2134170971', 'https://openalex.org/W2043861102', 'https://openalex.org/W2025594599', 'https://openalex.org/W2024386947', 'https://openalex.org/W2009793017', 'https://openalex.org/W1994946944', 'https://openalex.org/W1980330982', 'https://openalex.org/W1977015059'], 'abstract_inverted_index': {'A': [0], 'bstract': [1], ':': [2], 'Previous': [3], 'studies': [4], 'from': [5], 'our': [6], 'group': [7], 'have': [8, 196], 'shown': [9], 'that': [10, 39, 113, 176, 192], 'Foxa1': [11, 43, 115, 177], 'is': [12, 44], 'expressed': [13, 45, 182], 'in': [14, 46, 105, 167, 184, 202], 'the': [15, 20, 47, 53, 57, 73, 92, 121, 126, 168, 185, 193], 'prostate': [16, 186], 'and': [17, 33, 80, 116, 133, 158, 178, 187], 'interacts': [18, 51], 'with': [19, 52, 99, 120], 'androgen': [21, 89], 'receptor': [22], '(AR)': [23], 'to': [24, 55, 72, 146, 162], 'regulate': [25, 56], 'prostate‐specific': [26, 30, 100], 'genes': [27, 201], 'such': [28], 'as': [29], 'antigen': [31], '(PSA)': [32], 'probasin': [34], '(PB).': [35], 'We': [36], 'report': [37], 'here': [38], 'Foxa2': [40, 50, 71, 87, 98, 117, 179], 'but': [41], 'not': [42, 156], 'epididymis.': [48], 'Further,': [49], 'AR': [54, 134, 147, 159, 172], 'mouse': [58], 'epididymal': [59], 'retinoic': [60], 'acid': [61], 'binding': [62, 123, 148, 153, 164, 173], 'protein': [63, 143], '(mE‐RABP)': [64], 'gene,': [65], 'an': [66, 106, 171], 'epididymis‐specific': [67], 'gene.': [68], 'Binding': [69], 'of': [70, 86, 91, 97, 125, 170], 'mE‐RABP': [74, 93], 'promoter': [75, 94], 'was': [76, 135, 144, 160], 'confirmed': [77, 137], 'by': [78, 138], 'gel‐shift': [79, 139], 'chromatin': [81], 'immunoprecipitation': [82], '(ChIP)': [83], 'assays.': [84], 'Overexpression': [85], 'suppresses': [88], 'activation': [90], 'while': [95], 'overexpression': [96], 'promoters': [101], 'activates': [102], 'gene': [103], 'expression': [104], 'androgen‐independent': [107], 'manner.': [108], 'GST': [109], 'pull‐down': [110], 'assays': [111, 140], 'determined': [112], 'both': [114], 'physically': [118], 'interact': [119], 'DNA': [122], 'domain': [124], 'AR.': [127], 'The': [128], 'interaction': [129], 'between': [130], 'Foxa': [131, 142, 152, 163, 194], 'proteins': [132, 180, 195], 'further': [136], 'where': [141], 'recruited': [145, 161], 'oligomers': [149, 165], 'even': [150, 166], 'when': [151], 'sites': [154], 'were': [155], 'present,': [157], 'absence': [169], 'site.': [174], 'Given': [175], 'are': [181], 'differentially': [183], 'epididymis,': [188], 'these': [189], 'data': [190], 'suggest': [191], 'distinct': [197], 'effects': [198], 'on': [199], 'AR‐regulated': [200], 'different': [203], 'male': [204], 'reproductive': [205], 'accessory': [206], 'organs.': [207]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2134170971', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2025-01-21T02:14:05.159890', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
